Survival Outcomes with Regorafenib and/or Trifluridine/Tipiracil Sequencing to Rechallenge with Third-Line Regimens in Metastatic Colorectal Cancer: A Multicenter Retrospective Real-World Subgroup Comparison from the ReTrITA Study

Authors: Carlo Signorelli, Maria Alessandra Calegari, Annunziato Anghelone, Alessandro Passardi, Giovanni Luca Frassineti, Alessandro Bittoni, Jessica Lucchetti, Lorenzo Angotti, Emanuela Di Giacomo, Ina Valeria Zurlo, Cristina Morelli, Emanuela Dell’Aquila, Adele Artemi, Donatello Gemma, Domenico Cristiano Corsi, Alessandra Emiliani, Marta Ribelli, Federica Mazzuca, Giulia Arrivi, Federica Zoratto, Mario Giovanni Chilelli, Marta Schirripa, Maria Grazia Morandi, Fiorenza Santamaria, Manuela Dettori, Antonella Cosimati, Rosa Saltarelli, Alessandro Minelli, Emanuela Lucci-Cordisco, Michele Basso

Source: Current Oncology, Vol 31, Iss 12, Pp 7793-7808 (2024)

Subject Terms: metastatic colorectal cancer, rechallenge therapy, regorafenib, trifluridine/tipiracil, third-line therapy, real-world study, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/31/12/574; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/8ade5cd6afea4533954c4a90ced7bae3

Assessment of circulating tumor DNA in patients with locally advanced rectal cancer treated with neoadjuvant therapy

Authors: Chiara Molinari, Giorgia Marisi, George Laliotis, Erik Spickard, Ilario Giovanni Rapposelli, Elisabetta Petracci, Giby V. George, Punashi Dutta, Shruti Sharma, Meenakshi Malhotra, Andrea Prochowski Iamurri, Giacomo Feliciani, Minetta C. Liu, Paola Ulivi, Matteo Canale, Luca Saragoni, Graziana Gallo, Giovanni Luca Frassineti, Margherita Muratore, Antonino Romeo, Adham Jurdi, Giovanni Martinelli, Alessandro Passardi

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: Circulating tumor DNA, Locally advanced rectal cancer, Biomarker, Neoadjuvant therapy, NAR score, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/197e169f752440c5991a9a45abdaf52b

Impact of metformin, statin, aspirin and insulin on the prognosis of uHCC patients receiving first line Lenvatinib or Atezolizumab plus Bevacizumab

Authors: Margherita Rimini, Margarida Montes, Elisabeth Amadeo, Francesco Vitiello, Masatoshi Kudo, Toshifumi Tada, Goki Suda, Shigeo Shimose, Sara Lonardi, Fabian Finkelmeier, Francesca Salani, Lorenzo Antonuzzo, Fabio Marra, Massimo Iavarone, Giuseppe Cabibbo, Francesco Giuseppe Foschi, Marianna Silletta, Rodolfo Sacco, Ilario Giovanni Rapposelli, Mario Scartozzi, Pella Nicoletta, Luca Aldrighetti, Mara Persano, Silvia Camera, Federico Rossari, Silvia Foti, Takashi Kumada, Atsushi Hiraoka, Hideki Iwamoto, Mario Domenico Rizzato, Vera Himmelsbach, Gianluca Masi, Mattia Corradi, Ciro Celsa, Conti Fabio, Giovanni Luca Frassineti, Stefano Cascinu, Andrea Casadei-Gardini, Jose Presa

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Subject Terms: Advanced HCC, Atezolizumab, Bevacizumab, Lenvatinib BMI, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/41799d524b5a43689733a5a5474189a2

Squamous cell carcinoma of the stomach: focus on a heterogeneous disease at diagnosis. Case report and literature review

Authors: Manlio Monti, Francesco Limarzi, Devil Oboldi, Monica Sbrancia, Maria Caterina Pallotti, Giulia Miserocchi, Virginia Ghini, Sofia Zanuccoli, Sara Cagnazzo, Giovanni Luca Frassineti

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: primary squamous cell carcinoma of the stomach, gastric cancer, clinical characteristics, criteria for the diagnosis, immunohistochemistry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1419923/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/a6d80f65167c44e7ae0613f5f04af7f0

Prospective validation of VEGF and eNOS polymorphisms as predictors of first-line bevacizumab efficacy in patients with metastatic colorectal cancer

Authors: Giorgia Marisi, Irene Azzali, Alessandro Passardi, Francesca Rebuzzi, Giulia Bartolini, Milena Urbini, Matteo Canale, Chiara Molinari, Laura Matteucci, Francesco Giulio Sullo, Silvia Angela Debonis, Chiara Gallio, Graziana Gallo, Giovanni Luca Frassineti, Paola Ulivi

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/5cd50be5ac614657802f9ea9af386002

Serum Biomarkers to Dynamically Predict the Risk of Cardiovascular Events in Patients under Oncologic Therapy. A Multicenter Observational Study

Authors: Nicoletta Provinciali, Marco Piccininno, Giacomo Siri, Alessandra Gennari, Giancarlo Antonucci, Damiano Ricci, Emmanuela Devoto, Roberta Miceli, Pietro Cortesi, Chiara Pazzi, Oriana Nanni, Francesca Mannozzi, Ilaria Pastina, Luciana Messuti, Carmelo Bengala, Giovanni Luca Frassineti, Carlo Cattrini, Marianna Fava, Tania Buttiron Webber, Irene Maria Briata, Davide Corradengo, Andrea DeCensi, Matteo Puntoni

Source: Reviews in Cardiovascular Medicine, Vol 25, Iss 7, p 256 (2024)

Subject Terms: cardio-oncology, anticancer therapies, cardiovascular toxicity, stepp analysis, oxidative stress biomarkers, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.imrpress.com/journal/RCM/25/7/10.31083/j.rcm2507256; https://doaj.org/toc/1530-6550

Access URL: https://doaj.org/article/91d1f5ff789a46eebfeceec88c5656dd

Analysis of EVs from patients with advanced pancreatic cancer identifies antigens and miRNAs with predictive value

Authors: Ivan Vannini, Tania Rossi, Mattia Melloni, Martina Valgiusti, Milena Urbini, Alessandro Passardi, Giulia Bartolini, Chiara Gallio, Irene Azzali, Sara Bandini, Valentina Ancarani, Lorenzo Montanaro, Giovanni Luca Frassineti, Francesco Fabbri, Ilario Giovanni Rapposelli

Source: Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 473-482 (2023)

Subject Terms: extracellular vesicles, advanced pancreatic cancer, antigens, miRNAs, gemcitabine + nab-paclitaxel, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050123000712; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/f4b2d8528b39499baa2321b0ae8b0da0

Inflammatory indices as prognostic markers in metastatic colorectal cancer patients treated with chemotherapy plus Bevacizumab

Authors: Alessandro Passardi, Irene Azzali, Alessandro Bittoni, Giorgia Marisi, Francesca Rebuzzi, Chiara Molinari, Giulia Bartolini, Laura Matteucci, Francesco Giulio Sullo, Silvia Angela Debonis, Chiara Gallio, Manlio Monti, Martina Valgiusti, Margherita Muratore, Ilario Giovanni Rapposelli, Paola Ulivi, Giovanni Luca Frassineti

Source: Therapeutic Advances in Medical Oncology, Vol 15 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/7c76b2cc5c08402fb671d3dfe99c2c81

Hemophagocytic lymphohistiocytosis in gastric cancer: A rare syndrome for the oncologist. Case report and brief review

Authors: Manlio Monti, Giovanni Marconi, Andrea Ambrosini-Spaltro, Chiara Gallio, Virginia Ghini, Luca Esposito, Stefano Antonini, Daniela Montanari, Giovanni Luca Frassineti

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: hemophagocytic lymphohistiocytosis, gastric cancer, secondary hemophagocytic lymphohistiocytosis, disseminated intravascular coagulation, case report, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1010561/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/8d586ae4d3864deaad0359371b7d6d3e

Comprehensive analysis of DNA damage repair genes reveals pathogenic variants beyond BRCA and suggests the need for extensive genetic testing in pancreatic cancer

Authors: Ilario Giovanni Rapposelli, Valentina Zampiga, Ilaria Cangini, Valentina Arcangeli, Mila Ravegnani, Martina Valgiusti, Sara Pini, Stefano Tamberi, Giulia Bartolini, Alessandro Passardi, Giovanni Martinelli, Daniele Calistri, Giovanni Luca Frassineti, Fabio Falcini, Rita Danesi

Source: BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)

Subject Terms: Pancreatic cancer, DNA damage repair, Gene panel, Cancer susceptibility, Targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/eb588727dceb41739f721cc956da76f5

Takotsubo Syndrome (TTS) in Onco-Hematologic Patients: Retrospective Analysis and Focus on the Correlation or Not With Anticancer Drugs. Case Reports and Review of the Literature

Authors: Manlio Monti, Pietro Cortesi, Roberto Vespignani, Ilaria Bronico, Chiara Gallio, Michele Flospergher, Laura Matteucci, Giovanni Luca Frassineti

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: Takotsubo syndrome, monoclonal antibody, cancer, cardiovascular toxicity, adverse drug reactions, case report, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.875391/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/4f312b355ccc415692e9cd3673a666a6

Conversion Surgery in Gastric Cancer Carcinomatosis

Authors: Paolo Morgagni, Leonardo Solaini, Luca Saragoni, Manlio Monti, Martina Valgiusti, Giovanni Vittimberga, Giovanni Luca Frassineti, Massimo Framarini, Giorgio Ercolani

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: gastric cancer, conversion surgery, HIPEC, positive peritoneal cytology, metastatic disease, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.852559/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/e47ab252159a412e9c5d0c9d34829482

An Integrated Model to Improve Medication Reconciliation in Oncology: Prospective Interventional Study

Authors: Alessandro Passardi, Patrizia Serra, Caterina Donati, Federica Fiori, Sabrina Prati, Roberto Vespignani, Gabriele Taglioni, Patrizia Farfaneti Ghetti, Giovanni Martinelli, Oriana Nanni, Mattia Altini, Giovanni Luca Frassineti, Martina Vittoria Minguzzi

Source: Journal of Medical Internet Research, Vol 23, Iss 12, p e31321 (2021)

Subject Terms: Computer applications to medicine. Medical informatics, R858-859.7, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.jmir.org/2021/12/e31321; https://doaj.org/toc/1438-8871

Access URL: https://doaj.org/article/cfc82a1e9e4847f78202ac63c00860ff

Randomized phase II trial of avelumab alone or in combination with cetuximab for patients with previously treated, locally advanced, or metastatic squamous cell anal carcinoma: the CARACAS study

Authors: Matteo Fassan, Fotios Loupakis, Sara Lonardi, Federica Morano, Mariaelena Casagrande, Filippo Pietrantonio, Gianluca Masi, Marco Messina, Andrea Sartore-Bianchi, Paola Del Bianco, Francesca Bergamo, Angela Buonadonna, Vittorina Zagonel, Massimiliano Spada, Monica Ronzoni, Salvatore Corallo, Michele Prisciandaro, Giovanni Luca Frassineti, Alessandra Anna Prete, Vincenzo Formica, Domenico Cristiano Corsi, Corrado Orciuolo, Maria Giulia Zampino, Mario Scartozzi, Stefania Mosconi, Margherita Ratti, Emiliano Tamburini, Valentina Vettore

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/11/e002996.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/d2055ec40a69404eb78acf9876dff918

Case Report: The Added Value of Liquid Biopsy in Advanced Colorectal Cancer From Clinical Case Experiences

Authors: Paola Ulivi, Alessandro Passardi, Giorgia Marisi, Elisa Chiadini, Chiara Molinari, Matteo Canale, Luigi Pasini, Fabio Ferroni, Giovanni Luca Frassineti, Giulia Bartolini, Manlio Monti

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: CtDNA, metastatic colorectal cancer, RAS, mutations, case report, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.745701/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/83b520a2d9594b96bbf750402e9697ce

Case Report: Stevens-Johnson Syndrome and Hepatotoxicity Induced by Osimertinib Sequential to Pembrolizumab in a Patient With EGFR-Mutated Lung Adenocarcinoma

Authors: Caterina Gianni, Giuseppe Bronte, Angelo Delmonte, Marco Angelo Burgio, Kalliopi Andrikou, Manlio Monti, Cecilia Menna, Giovanni Luca Frassineti, Lucio Crinò

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: non-small cell lung cancer, pembrolizumab, osimertinib, stevens johnson syndrome, liver toxicity, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.672233/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/0f1b7f03c86348ed874f72983a9e218e

Melanoma metastasis mimicking gastric cancer: a challenge that starts from diagnosis

Authors: Manlio Monti, Massimo Guidoboni, Devil Oboldi, Giulia Bartolini, Federica Pieri, Silvia Ruscelli, Alessandro Passardi, Laura Ridolfi, Francesco De Rosa, Francesco Giulio Sullo, Giovanni Luca Frassineti

Source: Therapeutic Advances in Gastroenterology, Vol 14 (2021)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1756-2848

Access URL: https://doaj.org/article/2f3e3ead1a8c4b39a78b768f9283dac3

Neoadjuvant treatment (FOLFOX4 plus hypofractionated tomotherapy) for patients with locally advanced rectal cancer: a multicenter phase II trial

Authors: Alessandro Passardi, Ilario Giovanni Rapposelli, Emanuela Scarpi, Elisa Neri, Elisabetta Parisi, Giulia Ghigi, Giorgio Ercolani, Andrea Avanzolini, Davide Cavaliere, Britt Rudnas, Martina Valgiusti, Domenico Barone, Fabio Ferroni, Giovanni Luca Frassineti, Antonino Romeo

Source: Therapeutic Advances in Medical Oncology, Vol 12 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/4aa74caed7cc40f1ab6abc4f16776b35

Prognostic role of a new index (multi inflammatory index) in patients with metastatic colorectal cancer: results from the randomized ITACa trial

Authors: Andrea Casadei Gardini, Emanuela Scarpi, Martina Valgiusti, Manlio Monti, Silvia Ruscelli, Laura Matteucci, Giulia Bartolini, Bernadette Vertogen, Flavia Pagan, Giulia Rovesti, Giovanni Luca Frassineti, Alessandro Passardi

Source: Therapeutic Advances in Medical Oncology, Vol 12 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/3ad6aa8eecc44bb6918971f086096379

Effectiveness of bevacizumab in first- and second-line treatment for metastatic colorectal cancer: ITACa randomized trial

Authors: Elisabetta Petracci, Emanuela Scarpi, Alessandro Passardi, Annibale Biggeri, Carlo Milandri, Stefano Vecchia, Fabio Gelsomino, Davide Tassinari, Stefano Tamberi, Ilaria Bernardini, Caterina Accettura, Giovanni Luca Frassineti, Dino Amadori, Oriana Nanni

Source: Therapeutic Advances in Medical Oncology, Vol 12 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/f2076c860f5b400f8b894c34d14186f5