Effects of a ciliary neurotrophic factor (CNTF) small-molecule peptide mimetic in an in vitro and in vivo model of CDKL5 deficiency disorder

Authors: Nicola Mottolese, Manuela Loi, Stefania Trazzi, Marianna Tassinari, Beatrice Uguagliati, Giulia Candini, Khalid Iqbal, Giorgio Medici, Elisabetta Ciani

Source: Journal of Neurodevelopmental Disorders, Vol 16, Iss 1, Pp 1-19 (2024)

Subject Terms: Cdkl5 KO mice, CNTF, Brain development, Dendritic pathology, Neuronal survival, Neuroinflammation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/1866-1955

Access URL: https://doaj.org/article/32c9a83d8a9f412dab4164af5108f5ca

Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder

Authors: Marianna Tassinari, Beatrice Uguagliati, Stefania Trazzi, Camilla Bruna Cerchier, Ottavia Vera Cavina, Nicola Mottolese, Manuela Loi, Giulia Candini, Giorgio Medici, Elisabetta Ciani

Source: Neurobiology of Disease, Vol 182, Iss , Pp 106146- (2023)

Subject Terms: Cdkl5 KO mice, Brain development, Dendritic pathology, Neuronal survival, Neuroinflammation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996123001602; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/e4716d25c1e3418cbbfe63ef6ef10df1

Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder

Authors: Giuseppe Galvani, Nicola Mottolese, Laura Gennaccaro, Manuela Loi, Giorgio Medici, Marianna Tassinari, Claudia Fuchs, Elisabetta Ciani, Stefania Trazzi

Source: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-21 (2021)

Subject Terms: CDKL5, Neuroinflammation, Neuronal survival, Luteolin, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/3c91c0c420e84054b26876a55fdb9ad0

Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder

Authors: Nicola Mottolese, Beatrice Uguagliati, Marianna Tassinari, Camilla Bruna Cerchier, Manuela Loi, Giulia Candini, Roberto Rimondini, Giorgio Medici, Stefania Trazzi, Elisabetta Ciani

Source: Biomolecules, Vol 13, Iss 9, p 1396 (2023)

Subject Terms: Cdkl5 KO mice, voluntary exercise, brain development, dendritic pathology, neuronal survival, neuroinflammation, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/13/9/1396; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/3c06ae11e7254c588b29d066cc75346f

A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder

Authors: Laura Gennaccaro, Claudia Fuchs, Manuela Loi, Vincenzo Roncacè, Stefania Trazzi, Yassine Ait-Bali, Giuseppe Galvani, Anna Cecilia Berardi, Giorgio Medici, Marianna Tassinari, Elisa Ren, Roberto Rimondini, Maurizio Giustetto, Giorgio Aicardi, Elisabetta Ciani

Source: Neurobiology of Disease, Vol 153, Iss , Pp 105304- (2021)

Subject Terms: CDKL5, Synaptic plasticity, Dendritic pattern, Perirhinal cortex, GABAergic transmission, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S096999612100053X; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/3f1b1ea45f95440d9995c30bfaff2f22

Functional and Structural Impairments in the Perirhinal Cortex of a Mouse Model of CDKL5 Deficiency Disorder Are Rescued by a TrkB Agonist

Authors: Elisa Ren, Vincenzo Roncacé, Stefania Trazzi, Claudia Fuchs, Giorgio Medici, Laura Gennaccaro, Manuela Loi, Giuseppe Galvani, Keqiang Ye, Roberto Rimondini, Giorgio Aicardi, Elisabetta Ciani

Source: Frontiers in Cellular Neuroscience, Vol 13 (2019)

Subject Terms: CDKL5, synaptic plasticity, TrkB, PLCγ1, dendritic pattern, GluA2, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fncel.2019.00169/full; https://doaj.org/toc/1662-5102

Access URL: https://doaj.org/article/584f8066f1ce452582de3934e4f1aaf7

Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder

Authors: Claudia Fuchs, Laura Gennaccaro, Stefania Trazzi, Stefano Bastianini, Simone Bettini, Viviana Lo Martire, Elisa Ren, Giorgio Medici, Giovanna Zoccoli, Roberto Rimondini, Elisabetta Ciani

Source: Neural Plasticity, Vol 2018 (2018)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2090-5904; https://doaj.org/toc/1687-5443

Access URL: https://doaj.org/article/c4b1c22d6839485b9661f85875aa0f86

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Josephine la nuit

Authors: Giorgio Medici, Nidia di.

Access URL: http://hdl.handle.net/2027/mdp.39015074048938

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