Heterogeneity and viral replication fitness of HSV-1 clinical isolates with mutations in the thymidine kinase and DNA polymerase

Authors: Schalkwijk, Hanna Helena, Gillemot, Sarah, Reynders, Marijke, Selleslag, Dominik, Andrei, Graciela, Snoeck, Robert

Source: Journal of antimicrobial chemotherapy. 77(11):3153-3162

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163727206.0x000001&indx=1&recIds=ETOCvdc_100163727206.0x000001

Viral fitness of MHV-68 viruses harboring drug resistance mutations in the protein kinase or thymidine kinase

Authors: Trompet, Erika, Topalis, Dimitrios, Gillemot, Sarah, Snoeck, Robert, Andrei, Graciela

Source: In Antiviral Research October 2020 182

Persistent primary cytomegalovirus infection in a kidney transplant recipient: Multi-drug resistant and compartmentalized infection leading to graft loss

Authors: Andrei, Graciela, Van Loon, Elisabet, Lerut, Evelyne, Victoor, Jasper, Meijers, Björn, Bammens, Bert, Sprangers, Ben, Gillemot, Sarah, Fiten, Pierre, Opdenakker, Ghislain, Lagrou, Katrien, Kuypers, Dirk, Snoeck, Robert, Naesens, Maarten

Source: In Antiviral Research August 2019 168:203-209

Synchronous diversification of Sulawesi’s iconic artiodactyls driven by recent geological events

Authors: Frantz, Laurent A. F., Rudzinski, Anna, Nugraha, Abang Mansyursyah Surya, Evin, Allowen, Burton, James, Hulme-Beaman, Ardern, Linderholm, Anna, Barnett, Ross, Vega, Rodrigo, Irving-Pease, Evan K., Haile, James, Allen, Richard, Leus, Kristin, Shephard, Jill, Hillyer, Mia, Gillemot, Sarah, van den Hurk, Jeroen, Ogle, Sharron, Atofanei, Cristina, Thomas, Mark G., Johansson, Friederike, Mustari, Abdul Haris, Williams, John, Mohamad, Kusdiantoro, Damayanti, Chandramaya Siska, Wiryadik, Ita Djuwita, Obbles, Dagmar, Mona, Stephano, Day, Hally, Yasin, Muhammad, Meker, Stefan, McGuire, Jimmy A., Evans, Ben J., von Rintelen, Thomas, Ho, Simon Y. W., Searle, Jeremy B., Kitchener, Andrew C., Macdonald, Alastair A., Shaw, Darren J., Hall, Robert, Galbusera, Peter, Larson, Greger

Source: Proceedings: Biological Sciences, 2018 Apr 01. 285(1876), 1-8.

Access URL: https://www.jstor.org/stable/26545161

Thymidine kinase and protein kinase in drug-resistant herpesviruses: Heads of a Lernaean Hydra

Authors: Topalis, Dimitri, Gillemot, Sarah, Snoeck, Robert, Andrei, Graciela

Source: In Drug Resistance Updates March 2018 37:1-16

The Anti–Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase

Authors: Andrei, Graciela, Gillemot, Sarah, Topalis, Dimitrios, Snoeck, Robert

Source: The Journal of Infectious Diseases, 2018 Mar 01. 217(5), 790-801.

Access URL: https://www.jstor.org/stable/26494773

A European multi-centre External Quality Assessment (EQA) study on phenotypic and genotypic methods used for Herpes Simplex Virus (HSV) drug resistance testing

Authors: Afshar, Baharak, Bibby, David F., Piorkowska, Renata, Ohemeng-Kumi, Natasha, Snoeck, Robert, Andrei, Graciela, Gillemot, Sarah, Morfin, Florence, Frobert, Emilie, Burrel, Sonia, Boutolleau, David, Crowley, Brendan, Mbisa, Jean L.

Source: In Journal of Clinical Virology November 2017 96:89-93

Multidrug-resistant cytomegalovirus infection in a pediatric stem cell transplantation patient

Authors: Bauters, Tiene, Bordon, Victoria, Florin, Lisa, Padalko, Elizaveta, Andrei, Graciela, Gillemot, Sarah, Fiten, Pierre, Opdenakker, Ghislain, Snoeck, Robert, Laureys, Geneviève

Source: In Antiviral Research August 2016 132:149-153

A Herpes Simplex Virus 1 DNA Polymerase Multidrug Resistance Mutation Identified in a Patient With Immunodeficiency and Confirmed by Gene Editing.

Authors: Schalkwijk, Hanna Helena, Georgala, Aspasia, Gillemot, Sarah, Temblador, Arturo, Topalis, Dimitri, Wittnebel, Sebastian, Andrei, Graciela, Snoeck, Robert

Source: Journal of Infectious Diseases; Dec2023, Vol. 228 Issue 11, p1505-1515, 11p

Subject Terms: MULTIDRUG resistance, GENOME editing, DNA polymerases, GAIN-of-function mutations, DNA viruses, SEVERE combined immunodeficiency, STEM cell transplantation

Congenital cytomegalovirus infection despite valaciclovir secondary prevention: should we fear antiviral resistance?

Authors: Scohy, Anaïs ^⁎, Gillemot, Sarah, Dirix, Brecht, Bernard, Pierre, Andrei, Graciela, Snoeck, Robert, Kabamba Mukadi, Benoît

Source: In European Journal of Obstetrics & Gynecology and Reproductive Biology December 2024 303:367-368

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An MHV-68 Mutator Phenotype Mutant Virus, Confirmed by CRISPR/Cas9-Mediated Gene Editing of the Viral DNA Polymerase Gene, Shows Reduced Viral Fitness.

Authors: Trompet, Erika, Temblador, Arturo, Gillemot, Sarah, Topalis, Dimitrios, Snoeck, Robert, Andrei, Graciela

Source: Viruses (1999-4915); Jun2021, Vol. 13 Issue 6, p985, 1p

Subject Terms: DNA polymerases, PHENOTYPES, VIRAL genes, CRISPRS, VIRAL mutation, GENOME editing, HERPESVIRUSES, KAPOSI'S sarcoma-associated herpesvirus

Polymorphic microsatellite markers for the endangered goldenheaded lion tamarin, Leontopithecus chrysomelas (Callitrichidae).

Authors: Galbusera, Peter H. A., Gillemot, Sarah

Source: Conservation Genetics; Jun2008, Vol. 9 Issue 3, p731-733, 3p, 1 Chart

Subject Terms: ENDANGERED species, LION tamarins, TAMARINS, GENETIC polymorphisms, MICROSATELLITE repeats, WILDLIFE conservation, NATURE conservation, DEFORESTATION

Antiviral Drug-Resistance Typing Reveals Compartmentalization and Dynamics of Acyclovir-Resistant Herpes Simplex Virus Type-2 (HSV-2) in a Case of Neonatal Herpes.

Authors: Bache, Manon, Andrei, Graciela, Bindl, Lutz, Bofferding, Léon, Bottu, Jean, Géron, Christine, Neuhäuser, Christoph, Gillemot, Sarah, Fiten, Pierre, Opdenakker, Ghislain, Snoeck, Robert

Source: Journal of the Pediatric Infectious Diseases Society; Jun2014, Vol. 3 Issue 2, pe24-e27, 1p

Subject Terms: ANTIVIRAL agents, ACYCLOVIR, DRUG therapy, THERAPEUTICS