Concepts for agonistic targeting of CD40 in immuno-oncology

Authors: Richards, David M., Sefrin, Julian P., Gieffers, Christian, Hill, Oliver, Merz, Christian

Source: Human vaccines & immunotherapeutics. 16(2):377-387

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112997445.0x000001&indx=1&recIds=ETOCvdc_100112997445.0x000001

Anaphase-Promoting Complex/Cyclosome-Dependent Proteolysis of Human Cyclin a Starts at the Beginning of Mitosis and Is Not Subject to the Spindle Assembly Checkpoint

Authors: Geley, Stephan, Kramer, Edgar, Gieffers, Christian, Gannon, Julian, Peters, Jan-Michael, Hunt, Tim

Source: The Journal of Cell Biology, 2001 Apr 01. 153(1), 137-147.

Access URL: https://www.jstor.org/stable/1620429

Characterization of Vertebrate Cohesin Complexes and Their Regulation in Prophase

Authors: Sumara, Izabela, Vorlaufer, Elisabeth, Gieffers, Christian, Peters, Beate H., Peters, Jan-Michael

Source: The Journal of Cell Biology, 2000 Nov . 151(4), 749-761.

Access URL: https://www.jstor.org/stable/1620108

The RING-H2 Finger Protein APC11 and the E2 Enzyme UBC4 Are Sufficient to Ubiquitinate Substrates of the Anaphase-Promoting Complex

Authors: Gmachl, Michael, Gieffers, Christian, Podtelejnikov, Alexandre V., Mann, Matthias, Peters, Jan-Michael

Source: Proceedings of the National Academy of Sciences of the United States of America, 2000 Aug 01. 97(16), 8973-8978.

Access URL: https://www.jstor.org/stable/123114

The novel TRAIL-receptor agonist APG350 exerts superior therapeutic activity in pancreatic cancer cells

Authors: Legler, Karen, Hauser, Charlotte, Egberts, Jan-Hendrik, Willms, Anna, Heneweer, Carola, Boretius, Susann, Röcken, Christoph, Glüer, Claus-Christian, Becker, Thomas, Kluge, Michael, Hill, Oliver, Gieffers, Christian, Fricke, Harald, Kalthoff, Holger, Lemke, Johannes, Trauzold, Anna

Source: Cell death and disease. 9(5):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132430853.0x000001&indx=1&recIds=ETOCvdc_100132430853.0x000001

The Hexavalent CD40 Agonist HERA-CD40L Induces T-Cell–mediated Antitumor Immune Response Through Activation of Antigen-presenting Cells

Authors: Merz, Christian, Sykora, Jaromir, Marschall, Viola, Richards, David M., Heinonen, Karl, Redondo Müller, Mauricio, Thiemann, Meinolf, Schnyder, Tim, Fricke, Harald, Hill, Oliver, Gieffers, Christian

Source: Journal of immunotherapy. 41(9):385-398

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100069101720.0x000001&indx=1&recIds=ETOCvdc_100069101720.0x000001

Correction: CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells

Authors: Drachsler, Moritz, Kleber, Susanne, Mateos, Alvaro, Volk, Katrin, Mohr, Nadine, Chen, Si, Cirovic, Branko, Tüttenberg, Jochen, Gieffers, Christian, Sykora, Jaromir, Wirtz, Christian, Mueller, Wolf, Synowitz, Michael, Martin-Villalba, Ana

Source: Cell death and disease. 11(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174649990.0x000001&indx=1&recIds=ETOCvdc_100174649990.0x000001

Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro

Authors: Merz, Christian, Strecker, Alexander, Sykora, Jaromir, Hill, Oliver, Fricke, Harald, Angel, Peter, Gieffers, Christian, Peterziel, Heike

Source: Anti-cancer drugs. 26(7):716-727

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100037045379.0x000001&indx=1&recIds=ETOCvdc_100037045379.0x000001

HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality

Authors: Richards, David M., Marschall, Viola, Billian-Frey, Katharina, Heinonen, Karl, Merz, Christian, Redondo Müller, Mauricio, Sefrin, Julian P., Schröder, Matthias, Sykora, Jaromir, Fricke, Harald, Hill, Oliver, Gieffers, Christian, Thiemann, Meinolf

Source: Journal for immunotherapy of cancer. 7(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130995239.0x000001&indx=1&recIds=ETOCvdc_100130995239.0x000001

The CD40 agonist HERA-CD40L results in enhanced activation of antigen presenting cells, promoting an anti-tumor effect alone and in combination with radiotherapy.

Authors: Frankish, Jamie, Mukherjee, Debayan, Romano, Erminia, Billian-Frey, Katharina, Schröder, Matthias, Heinonen, Karl, Merz, Christian, Müller, Mauricio Redondo, Gieffers, Christian, Hill, Oliver, Thiemann, Meinolf, Honeychurch, Jamie, Illidge, Tim, Sykora, Jaromir

Source: Frontiers in Immunology; 2023, p1-16, 16p

Subject Terms: ANTIGEN presenting cells, TUMOR necrosis factors, MYELOID cells, IMMUNOREGULATION, DENDRITIC cells

The Death Receptor CD95 Activates Adult Neural Stem Cells for Working Memory Formation and Brain Repair

Authors: Corsini, Nina S., Sancho-Martinez, Ignacio, Laudenklos, Sabrina, Glagow, Désirée, Kumar, Sachin, Letellier, Elisabeth, Koch, Philipp, Teodorczyk, Marcin, Kleber, Susanne, Klussmann, Stefan, Wiestler, Benedict, Brüstle, Oliver, Mueller, Wolf, Gieffers, Christian, Hill, Oliver, Thiemann, Meinolf, Seedorf, Matthias, Gretz, Norbert, Sprengel, Rolf, Celikel, Tansu, Martin-Villalba, Ana

Source: In Cell Stem Cell 2009 5(2):178-190

Molecular Characterization of NDP52, A Novel Protein of the Nuclear Domain 10, Which Is Redistributed upon Virus Infection and Interferon Treatment

Authors: Korioth, Frank, Gieffers, Christian, Maul, Gerd G., Frey, Jürgen

Source: The Journal of Cell Biology, 1995 Jul 01. 130(1), 1-13.

Access URL: https://www.jstor.org/stable/1616994

Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma

Authors: Kleber, Susanne, Sancho-Martinez, Ignacio, Wiestler, Benedict, Beisel, Alexandra, Gieffers, Christian, Hill, Oliver, Thiemann, Meinolf, Mueller, Wolf, Sykora, Jaromir, Kuhn, Andreas, Schreglmann, Nina, Letellier, Elisabeth, Zuliani, Cecilia, Klussmann, Stefan, Teodorczyk, Marcin, Gröne, Hermann-Josef, Ganten, Tom M., Sültmann, Holger, Tüttenberg, Jochen, von Deimling, Andreas, Regnier-Vigouroux, Anne, Herold-Mende, Christel, Martin-Villalba, Ana

Source: In Cancer Cell 2008 13(3):235-248

Fusion proteins forming trimers

Compounds for treating beta-amyloidoses

Multimeric TNF receptor fusion proteins and nucleic acids encoding same

TNF superfamily member light fusion proteins

TNF Superfamily Fusion Proteins

CD95L or trail fusion proteins

FUSION PROTEINS FORMING TRIMERS