Chemosensory assessment and impact on quality of life in neurosensorial cluster of the post COVID 19 syndrome

Authors: Elisa Gentilotti, Anna Gorska, Maria Paola Cecchini, Massimo Mirandola, Marco Meroi, Pasquale De Nardo, Andrea Sartori, Chiara Konishi De Toffoli, Samir Kumar-Singh, Gianluigi Zanusso, Salvatore Monaco, Evelina Tacconelli, the ORCHESTRA-UNIVR Study Group

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Subject Terms: Chemosensory impairment, Post-COVID syndrome, SARS-CoV-2 long-term sequelae, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f1ab2f90ad2b49a3ad79b0d42c7c25d6

Enhanced quantitation of pathological α-synuclein in patient biospecimens by RT-QuIC seed amplification assays.

Authors: Ankit Srivastava, Qinlu Wang, Christina D Orrù, Manel Fernandez, Yaroslau Compta, Bernardino Ghetti, Gianluigi Zanusso, Wen-Quan Zou, Byron Caughey, Catherine A A Beauchemin

Source: PLoS Pathogens, Vol 20, Iss 9, p e1012554 (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/7e7fff4ad6e84eaf8f60096f97bc039f

Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces.

Authors: Christina D Orrú, Bradley R Groveman, Andrew G Hughson, Tomás Barrio, Kachi Isiofia, Brent Race, Natalia C Ferreira, Pierluigi Gambetti, David A Schneider, Kentaro Masujin, Kohtaro Miyazawa, Bernardino Ghetti, Gianluigi Zanusso, Byron Caughey

Source: PLoS Pathogens, Vol 20, Iss 4, p e1012175 (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012175&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/e41f9f194a98464797ac114a7b488335

Sporadic Creutzfeldt–Jakob disease infected human cerebral organoids retain the original human brain subtype features following transmission to humanized transgenic mice

Authors: Bradley R. Groveman, Brent Race, Simote T. Foliaki, Katie Williams, Andrew G. Hughson, Chase Baune, Gianluigi Zanusso, Cathryn L. Haigh

Source: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)

Subject Terms: Sporadic CJD, Subtype, Prion, PrP, Cerebral organoid, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/3c5bd4382a434ac5b0e23d8a75101206

Olfactory swab sampling optimization for α-synuclein aggregate detection in patients with Parkinson’s disease

Authors: Matilde Bongianni, Mauro Catalan, Daniela Perra, Elena Fontana, Francesco Janes, Claudio Bertolotti, Luca Sacchetto, Stefano Capaldi, Matteo Tagliapietra, Paola Polverino, Valentina Tommasini, Giulia Bellavita, Elham Ataie Kachoie, Roberto Baruca, Andrea Bernardini, Mariarosaria Valente, Michele Fiorini, Erika Bronzato, Stefano Tamburin, Laura Bertolasi, Lorenzo Brozzetti, Maria Paola Cecchini, Gianluigi Gigli, Salvatore Monaco, Paolo Manganotti, Gianluigi Zanusso

Source: Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-11 (2022)

Subject Terms: Parkinson disease, Alpha-synuclein, Real-time quaking-induced conversion assay, Olfactory mucosa, Cerebrospinal fluid, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9158

Access URL: https://doaj.org/article/e4db3ec8ee7a4112bd5090655fa77fc5

Corrigendum: PMCA-based detection of prions in the olfactory mucosa of patients with sporadic Creutzfeldt–Jakob disease

Authors: Federico Angelo Cazzaniga, Edoardo Bistaffa, Chiara Maria Giulia De Luca, Sara Maria Portaleone, Marcella Catania, Veronica Redaelli, Irene Tramacere, Giuseppe Bufano, Martina Rossi, Paola Caroppo, Anna Rita Giovagnoli, Pietro Tiraboschi, Giuseppe Di Fede, Roberto Eleopra, Grazia Devigili, Antonio Emanuele Elia, Roberto Cilia, Michele Fiorini, Matilde Bongianni, Giulia Salzano, Luigi Celauro, Federico Giuseppe Quarta, Angela Mammana, Giuseppe Legname, Fabrizio Tagliavini, Piero Parchi, Gianluigi Zanusso, Giorgio Giaccone, Fabio Moda

Source: Frontiers in Aging Neuroscience, Vol 15 (2023)

Subject Terms: Creutzfeldt–Jakob disease, olfactory mucosa, protein misfolding cyclic amplification, neurodegeneration, prion, peripheral biomarker, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1073356/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/f36d14b05e854b90b710f3688c676a6c

Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt–Jakob disease

Authors: Bradley R. Groveman, Natalia C. Ferreira, Simote T. Foliaki, Ryan O. Walters, Clayton W. Winkler, Brent Race, Andrew G. Hughson, Gianluigi Zanusso, Cathryn L. Haigh

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/349388bbff72452db46c3047ea9cc10f

Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD

Authors: Christina D. Orrú, Bradley R. Groveman, Aaron Foutz, Matilde Bongianni, Franco Cardone, Neil McKenzie, Audrey Culeux, Anna Poleggi, Katarina Grznarova, Daniela Perra, Michele Fiorini, Xiaoqin Liu, Anna Ladogana, Marco Sbriccoli, Andrew G. Hughson, Stéphane Haïk, Alison J. Green, Michael D. Geschwind, Maurizio Pocchiari, Jiri G. Safar, Gianluigi Zanusso, Byron Caughey

Source: Annals of Clinical and Translational Neurology, Vol 7, Iss 11, Pp 2262-2271 (2020)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2328-9503

Access URL: https://doaj.org/article/bb5874f625804d7ba24ed64e6f1053e6

Transmission of CJD from nasal brushings but not spinal fluid or RT‐QuIC product

Authors: Gregory J. Raymond, Brent Race, Christina D. Orrú, Lynne D. Raymond, Matilde Bongianni, Michele Fiorini, Bradley R. Groveman, Sergio Ferrari, Luca Sacchetto, Andrew G. Hughson, Salvatore Monaco, Maurizio Pocchiari, Gianluigi Zanusso, Byron Caughey

Source: Annals of Clinical and Translational Neurology, Vol 7, Iss 6, Pp 932-944 (2020)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2328-9503

Access URL: https://doaj.org/article/5a35bd9fe3b8478e84663fd9e528c5a1

Transmission characteristics of heterozygous cases of Creutzfeldt-Jakob disease with variable abnormal prion protein allotypes

Authors: Anne Ward, Jason R. Hollister, Kristin McNally, Diane L. Ritchie, Gianluigi Zanusso, Suzette A. Priola

Source: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)

Subject Terms: Prion, Creutzfeldt-Jakob disease, CJD, PrPSc allotype, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-020-00958-x; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/52a3312ba504400f8ed988df193ecc1e

PMCA-Based Detection of Prions in the Olfactory Mucosa of Patients With Sporadic Creutzfeldt–Jakob Disease

Authors: Federico Angelo Cazzaniga, Edoardo Bistaffa, Chiara Maria Giulia De Luca, Sara Maria Portaleone, Marcella Catania, Veronica Redaelli, Irene Tramacere, Giuseppe Bufano, Martina Rossi, Paola Caroppo, Anna Rita Giovagnoli, Pietro Tiraboschi, Giuseppe Di Fede, Roberto Eleopra, Grazia Devigili, Antonio Emanuele Elia, Roberto Cilia, Michele Fiorini, Matilde Bongianni, Giulia Salzano, Luigi Celauro, Federico Giuseppe Quarta, Angela Mammana, Giuseppe Legname, Fabrizio Tagliavini, Piero Parchi, Gianluigi Zanusso, Giorgio Giaccone, Fabio Moda

Source: Frontiers in Aging Neuroscience, Vol 14 (2022)

Subject Terms: Creutzfeldt–Jakob disease, olfactory mucosa, protein misfolding cyclic amplification, neurodegeneration, prion, peripheral biomarker, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2022.848991/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/4a98baad86204ee3be173b36f764ec46

Evidence of SARS-CoV-2 in nasal brushings and olfactory mucosa biopsies of COVID-19 patients

Authors: Carlotta Pipolo, Daniele Bottai, Emanuela Fuccillo, Eleonora Aronica, Fabio Bruschi, Antonio Mario Bulfamante, Luca Castellani, Maria Paola Canevini, Davide Chiumello, Sergio Ferrari, Carla Martinelli, Stefano Muttini, Alberto Priori, Alberto Maria Saibene, Chiara Spoldi, Delfina Tosi, Gianluigi Zanusso, Gaetano Pietro Bulfamante, Giovanni Felisati

Source: PLoS ONE, Vol 17, Iss 4 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9004784/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/692522f23aba4446aca63ff3fb5e235a

A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases

Authors: Michael A. Metrick, Natália do Carmo Ferreira, Eri Saijo, Allison Kraus, Kathy Newell, Gianluigi Zanusso, Michele Vendruscolo, Bernardino Ghetti, Byron Caughey

Source: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)

Subject Terms: RT-QuIC, Tau, Pick disease, Alzheimer disease, Chronic traumatic encephalopathy, Neurodegeneration, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-020-0887-z; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/a4d5a6e3f1d74090b4a3020b237af203

α‐Synuclein RT‐QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies

Authors: Matilde Bongianni, Anna Ladogana, Stefano Capaldi, Sigrid Klotz, Simone Baiardi, Annachiara Cagnin, Daniela Perra, Michele Fiorini, Anna Poleggi, Giuseppe Legname, Tatiana Cattaruzza, Francesco Janes, Massimo Tabaton, Bernardino Ghetti, Salvatore Monaco, Gabor G. Kovacs, Piero Parchi, Maurizio Pocchiari, Gianluigi Zanusso

Source: Annals of Clinical and Translational Neurology, Vol 6, Iss 10, Pp 2120-2126 (2019)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2328-9503

Access URL: https://doaj.org/article/f4deb6fe7ffd42969999bc511093e3f8

Sporadic Creutzfeldt-Jakob disease prion infection of human cerebral organoids

Authors: Bradley R. Groveman, Simote T. Foliaki, Christina D. Orru, Gianluigi Zanusso, James A. Carroll, Brent Race, Cathryn L. Haigh

Source: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)

Subject Terms: Prion, CJD, Human cerebral organoid, Induced pluripotent stem cells, RT-QuIC, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-019-0742-2; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/9d2522f5b8ef46879d6c6efd4b996b79

Correction: Olfactory swab sampling optimization for α-synuclein aggregate detection in patients with Parkinson’s disease

Authors: Matilde Bongianni, Mauro Catalan, Daniela Perra, Elena Fontana, Francesco Janes, Claudio Bertolotti, Luca Sacchetto, Stefano Capaldi, Matteo Tagliapietra, Paola Polverino, Valentina Tommasini, Giulia Bellavita, Elham Ataie Kachoie, Roberto Baruca, Andrea Bernardini, Mariarosaria Valente, Michele Fiorini, Erika Bronzato, Stefano Tamburin, Laura Bertolasi, Lorenzo Brozzetti, Maria Paola Cecchini, Gianluigi Gigli, Salvatore Monaco, Paolo Manganotti, Gianluigi Zanusso

Source: Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-1 (2022)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9158

Access URL: https://doaj.org/article/42c356c5411345358107a3b0369a30a4

Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer’s disease

Authors: Mirta Borin, Claudia Saraceno, Marcella Catania, Erika Lorenzetto, Valeria Pontelli, Anna Paterlini, Silvia Fostinelli, Anna Avesani, Giuseppe Di Fede, Gianluigi Zanusso, Luisa Benussi, Giuliano Binetti, Simone Zorzan, Roberta Ghidoni, Mario Buffelli, Silvia Bolognin

Source: Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-17 (2018)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-018-0567-4; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/11d0fb5036e34d868ddf83de50c56590

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

Authors: Bradley R. Groveman, Christina D. Orrù, Andrew G. Hughson, Lynne D. Raymond, Gianluigi Zanusso, Bernardino Ghetti, Katrina J. Campbell, Jiri Safar, Douglas Galasko, Byron Caughey

Source: Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-10 (2018)

Subject Terms: Parkinson, Lewy body, Alzheimer, Diagnosis, Synuclein, Amplification, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-018-0508-2; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/0d9bd34d07954635a1bb8e7f7cbb63e7

Correction to: Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

Authors: Bradley R. Groveman, Christina D. Orrù, Andrew G. Hughson, Lynne D. Raymond, Gianluigi Zanusso, Bernardino Ghetti, Katrina J. Campbell, Jiri Safar, Douglas Galasko, Byron Caughey

Source: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-2 (2020)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-020-01052-y; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/d8d3b2642583429faa27361600113b29

Neurodegeneration-Associated Proteins in Human Olfactory Neurons Collected by Nasal Brushing

Authors: Lorenzo Brozzetti, Luca Sacchetto, Maria Paola Cecchini, Anna Avesani, Daniela Perra, Matilde Bongianni, Corinne Portioli, Maria Scupoli, Bernardino Ghetti, Salvatore Monaco, Mario Buffelli, Gianluigi Zanusso

Source: Frontiers in Neuroscience, Vol 14 (2020)

Subject Terms: olfactory neurons, olfactory neuroepithelium, olfactory brushing, neurodegenerative diseases, misfolded proteins, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnins.2020.00145/full; https://doaj.org/toc/1662-453X

Access URL: https://doaj.org/article/f468805d3770426a8e777867a70faca5