A novel synthetised sulphonylhydrazone coumarin (E)‐4‐methyl‐N′‐(1‐(3‐oxo‐3H‐benzo[f]chromen‐2‐ yl)ethylidene)benzenesulphonohydrazide protect against isoproterenol‐induced myocardial infarction in rats by attenuating oxidative damage, biological changes and electrocardiogram

Authors: Ghazouani, Lakhdar, Khdhiri, Emna, Elmufti, Afoua, Zarei, Armin, Feriani, Anouar, Baaziz, Intissar, Hajji, Raouf, Abid, Majdi, Ammar, Houcine, Abid, Souhir, Allouche, Noureddine, Mnafgui, Kais, Ramazani, Ali, Tlili, Nizar

Source: Clinical and experimental pharmacology and physiology. 49(9):1010-1026

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162250452.0x000001&indx=1&recIds=ETOCvdc_100162250452.0x000001

Phytochemical Profiling of Ephedra alata subsp. alenda Seeds by High-Performance Liquid Chromatography—Electrospray Ionization—Quadrupole-Time-of-Flight-Mass Spectrometry (HPLC-ESI-QTOF-MS), Molecular Docking, and Antioxidant, Anti-diabetic, and Acetylcholinesterase Inhibition

Authors: Mufti, Afoua, Tir, Meriam, Zarei, Armin, Contreras, María del Mar, Gómez-Cruz, Irene, Feriani, Anouar, Ghazouani, Lakhdar, Saadaoui, Ezzeddine, Allagui, Mohamed Salah, Harrath, Abdel Halim, Ramazani, Ali, Tlili, Nizar

Source: Analytical letters. 55(15):2450-2466

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Anti-embolic and anti-oxidative effects of a novel (E)-4-amino-N′-(1-(7-hydroxy-2-oxo-2H-chromen-3-yl) ethylidene) benzohydrazide against isoproterenol and vitamin-K induced ischemic stroke

Authors: Mnafgui, Kais, Khdhiri, Emna, Ghazouani, Lakhdar, Ncir, Marwa, Zaafouri, Zouhaier, Allouche, Noureddine, Elfeki, Abdelfattah, Ammar, Houcine, Abid, Souhir, Hajji, Raouf

Source: Archives of physiology and biochemistry. 127(6):527-540

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(E)-N’-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide protecting rat heart tissues from isoproterenol toxicity: Evidence from in vitro and in vivo tests

Authors: Khdhiri, Emna, Mnafgui, Kais, Ghazouani, Lakhdar, Feriani, Anouar, Hajji, Raouf, Bouzanna, Walid, Allouche, Noureddine, Bazureau, Jean-Pierre, Ammar, Houcine, Abid, Souhir

Source: In European Journal of Pharmacology 15 August 2020 881

Zygophyllum album saponins prevent atherogenic effect induced by deltamethrin via attenuating arterial accumulation of native and oxidized LDL in rats

Authors: Feriani, Anouar, Tir, Meriam, Hachani, Rafik, Gómez-Caravaca, Ana María, Contreras, María del Mar, Taamalli, Amani, Talhaoui, Nassima, Segura-Carretero, Antonio, Ghazouani, Lakhdar, Mufti, Afoua, Tlili, Nizar, El Feki, Abdelfattah, Harrath, Abdel Halim, Allagui, Mohamed Salah

Source: In Ecotoxicology and Environmental Safety 15 April 2020 193

Toxic effect of alpha cypermethrin, an environmental pollutant, on myocardial tissue in male wistar rats

Authors: Ghazouani, Lakhdar, Feriani, Anouar, Mufti, Afoua, Tir, Meriam, Baaziz, Intissar, Mansour, Hedi Ben, Mnafgui, Kais

Source: Environmental science and pollution research international. 27(6):5709-5717

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164217593.0x000001&indx=1&recIds=ETOCvdc_100164217593.0x000001

Bifenthrin exerts proatherogenic effects via arterial accumulation of native and oxidized LDL in rats: the beneficial role of vitamin E and selenium

Authors: Feriani, Anouar, Hachani, Rafik, Tir, Meriam, Ghazouani, Lakhdar, Mufti, Afoua, Borgi, Mohamed Ali, Allagui, Mohamed Salah

Source: Environmental science and pollution research international. 27(6):5651-5660

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164217589.0x000001&indx=1&recIds=ETOCvdc_100164217589.0x000001

Structural Characterization and Cardioprotective Effect of Water-Soluble Polysaccharides Extracted from Clematis flammula.

Authors: Baaziz, Intissar¹, Ghazouani, Lakhdar¹, Rjeibi, Ilhem¹, Feriani, Anouar¹, Mnafgui, Kais², Mufti, Afoua¹, Traikia, Mounir³, Le Cerf, Didier⁴, Michaud, Philippe⁵, Pierre, Guillaume⁵, guillaume.pierre@uca.fr, Cherif, Slim⁶

Source: Applied Sciences (2076-3417); Nov2022, Vol. 12 Issue 21, p10818, 18p

Protective effect of Globularia alypum leaves against deltamethrin-induced nephrotoxicity in rats and determination of its bioactive compounds using high-performance liquid chromatography coupled with electrospray ionization tandem quadrupole–time-of-flight mass spectrometry

Authors: Feriani, Anouar, del Mar Contreras, María, Talhaoui, Nassima, Gómez-Caravaca, Ana María, Taamalli, Amani, Segura-Carretero, Antonio, Ghazouani, Lakhdar, El Feki, Abdelfatteh, Allagui, Mohamed Salah

Source: In Journal of Functional Foods May 2017 32:139-148

Cardiopreventive capacity of a novel (E)‐Nʹ‐(1‐(7‐methoxy‐2‐oxo‐2H‐chromen‐3‐yl) ethylidene)‐4‐methylbenzenesulfonohydrazide against isoproterenol‐induced myocardial infarction by moderating biochemical, oxidative stress, and histological parameters

Authors: Khdhiri, Emna, Mnafgui, Kais, Ncir, Marwa, Feriani, Anouar, Ghazouani, Lakhdar, Hajji, Raouf, Jallouli, Dana, Abid, Majdi, Jamoussi, Kamel, Allouche, Noureddine, Ammar, Houcine, Abid, Souhir

Source: Journal of biochemical and molecular toxicology. 35(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122774763.0x000001&indx=1&recIds=ETOCvdc_100122774763.0x000001

Persistent plasticizers and bisphenol in the cheese of Tunisian markets induced biochemical and histopathological alterations in male BALB/c mice

Authors: Beltifa, Asma, Feriani, Anouar, Macherki, Monia, Ghorbel, Asma, Ghazouani, Lakhdar, Di Bella, Giuseppa, Sire, Olivier, Van Loco, Joris, Reyns, Tim, Mansour, Hedi Ben

Source: Environmental science and pollution research international. 25(7):6545-6557

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HPLC-DAD-ESI-QTOF-MS/MS profiling of Zygophyllum album roots extract and assessment of its cardioprotective effect against deltamethrin-induced myocardial injuries in rat, by suppression of oxidative stress-related inflammation and apoptosis via NF-κB signaling pathway

Authors: Feriani, Anouar, Tir, Meriam, Gómez-Caravaca, Ana María, Contreras, María del Mar, Talhaoui, Nassima, Taamalli, Amani, Segura-Carretero, Antonio, Ghazouani, Lakhdar, Mufti, Afoua, Tlili, Nizar, Allagui, Mohamed Salah

Source: Journal of ethnopharmacology. 247

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100091150004.0x000001&indx=1&recIds=ETOCvdc_100091150004.0x000001

Cardioprotective effects of (E)-4-hydroxy-N′-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide: a newly synthesized coumarin hydrazone against isoproterenol-induced myocardial infarction in a rat model.

Authors: Ghazouani, Lakhdar¹ (AUTHOR) ghazouani2005@yahoo.fr, Khdhiri, Emna² (AUTHOR), Elmufti, Afoua^1,3 (AUTHOR), Feriani, Anouar^1,4 (AUTHOR), Tir, Meriam^3,5 (AUTHOR), Baaziz, Intissar^1,6 (AUTHOR), Hajji, Raouf^4,7 (AUTHOR), Ben Mansour, Hedi^1,5 (AUTHOR), Ammar, Houcine² (AUTHOR), Abid, Souhir^1,2,6 (AUTHOR), Mnafgui, Kais^3,7 (AUTHOR)

Source: Canadian Journal of Physiology & Pharmacology. 2019, Vol. 97 Issue 10, p989-998. 10p.

Subject Terms: *MYOCARDIAL infarction, *RAYLEIGH waves, *BENZOPYRENE, *ALANINE aminotransferase, *LACTATE dehydrogenase, *HEART beat, *ANTHRACYCLINES, *MICROFILAMENT proteins

Company/Entity: INTERNATIONAL Organization for Standardization

174G>C interleukin-6 gene polymorphism in Tunisian patients with coronary artery disease

Authors: Ghazouani Lakhdar, Abboud Nesrine, Khalifa Sonia, Added Faouzi, Khalfallah Ali, Nsiri Brahim, Mediouni Mounira, Mahjoub Touhami

Source: Annals of Saudi Medicine, Vol 31, Iss 1, Pp 40-44 (2011)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://www.saudiannals.net/article.asp?issn=0256-4947;year=2011;volume=31;issue=1;spage=40;epage=44;aulast=Ghazouani; https://doaj.org/toc/0256-4947; https://doaj.org/toc/0975-4466

Access URL: https://doaj.org/article/28d900a32b0d4208a73cc86ddfaa05cc

TNF-α −308G > A and IL-6 −174G > C polymorphisms in Tunisian patients with coronary artery disease

Authors: Ghazouani, Lakhdar, Hadj Khalifa, Sonia Ben, Abboud, Nesrine, Hamda, Khaldoun Ben, Khalfallah, Ali Ben, Brahim, Nsiri, Almawi, Wassim Youssef, Mahjoub, Touhami

Source: In Clinical Biochemistry 2010 43(13):1085-1089

Oleuropein Protects Against Cerebral Ischemia Injury in Rats: Molecular Docking, Biochemical and Histological Findings.

Authors: Mnafgui, Kais¹ (AUTHOR) kaismnafgui@gmail.com, Ghazouani, Lakhdar² (AUTHOR), Hajji, Raouf³ (AUTHOR), Tlili, Abir⁴ (AUTHOR), Derbali, Fatma³ (AUTHOR), da Silva, Francisco Ivan⁵ (AUTHOR), Araújo, Joabe Lima⁶ (AUTHOR), de Oliveira Schinoff, Bianca⁷ (AUTHOR), Bachega, José Fernando Ruggiero^7,8 (AUTHOR), da Silva Santos, Antônia Laíres⁵ (AUTHOR), Allouche, Noureddine⁹ (AUTHOR)

Source: Neurochemical Research. Aug2021, Vol. 46 Issue 8, p2131-2142. 12p.

Subject Terms: *ANGIOTENSIN converting enzyme, *CEREBRAL ischemia, *PROTEIN disulfide isomerase, *LABORATORY rats, *ISCHEMIC stroke, *MOLECULAR docking, *CEREBRAL arteries

Zygophyllum album leaves extract prevented hepatic fibrosis in rats, by reducing liver injury and suppressing oxidative stress, inflammation, apoptosis and the TGF-β1/Smads signaling pathways. Exploring of bioactive compounds using HPLC–DAD–ESI–QTOF-MS/MS

Authors: Feriani, Anouar, Tir, Meriam, Gómez-Caravaca, Ana María, del Mar Contreras, María, Taamalli, Amani, Segura-Carretero, Antonio, Ghazouani, Lakhdar, Mufti, Afoua, Tlili, Nizar, El Feki, Abdelfattah, Harrath, Abdel Halim, Allagui, Mohamed Salah

Source: Inflammopharmacology; Dec2020, Vol. 28 Issue 6, p1735-1750, 16p

Subject Terms: HEPATIC fibrosis, OXIDATIVE stress, BIOACTIVE compounds, LIVER injuries, APOPTOSIS

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(E)-N′-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis.

Authors: Feriani, Anouar, Khdhiri, Emna, Tir, Meriam, Elmufti, Afoua, Tlili, Nizar, Hajji, Raouf, Ammar, Houcine, Allouche, Noureddine, Abid, Souhir, Ghazouani, Lakhdar, Mnafgui, Kais

Source: Oxidative Medicine & Cellular Longevity; 3/6/2020, p1-15, 15p