Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Authors: Zhao, Yaqi, Short, Nicholas J., Kantarjian, Hagop M., Chang, Ti-Cheng, Ghate, Pankaj S., Qu, Chunxu, Macaron, Walid, Jain, Nitin, Thakral, Beenu, Phillips, Aaron H., Khoury, Joseph, Garcia-Manero, Guillermo, Zhang, Wenchao, Fan, Yiping, Yang, Hui, Garris, Rebecca S., Nasr, Lewis F., Kriwacki, Richard W., Roberts, Kathryn G., Konopleva, Marina, Jabbour, Elias J., Mullighan, Charles G.

Source: In Blood 4 July 2024 144(1):61-73

The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Authors: Gao, Qingsong, Ryan, Sarra L., Iacobucci, Ilaria, Ghate, Pankaj S., Cranston, Ruth E., Schwab, Claire, Elsayed, Abdelrahman H., Shi, Lei, Pounds, Stanley, Lei, Shaohua, Baviskar, Pradyuamna, Pei, Deqing, Cheng, Cheng, Bashton, Matthew, Sinclair, Paul, Bentley, David R., Ross, Mark T., Kingsbury, Zoya, James, Terena, Roberts, Kathryn G., Devidas, Meenakshi, Fan, Yiping, Chen, Wenan, Chang, Ti-Cheng, Wu, Gang, Carroll, Andrew, Heerema, Nyla, Valentine, Virginia, Valentine, Marcus, Yang, Wenjian, Yang, Jun J., Moorman, Anthony V., Harrison, Christine J., Mullighan, Charles G.

Source: In Blood 24 August 2023 142(8):711-723

The orally bioavailable GSPT1/2 degrader SJ6986 exhibits in vivo efficacy in acute lymphoblastic leukemia

Authors: Chang, Yunchao, Keramatnia, Fatemeh, Ghate, Pankaj S., Nishiguchi, Gisele, Gao, Qingsong, Iacobucci, Ilaria, Yang, Lei, Chepyala, Divyabharathi, Mishra, Ashutosh, High, Anthony A., Goto, Hiroaki, Akahane, Koshi, Peng, Junmin, Yang, Jun J., Fischer, Marcus, Rankovic, Zoran, Mullighan, Charles G.

Source: In Blood 17 August 2023 142(7):629-642

The Warburg micro syndrome protein RAB3GAP1 modulates neuronal morphogenesis and interacts with axon elongation end ER-Golgi trafficking factors

Authors: Ghate, Pankaj S., Vacharasin, Janay M., Ward, Joseph A., Nowling, Duncan, Kay, Valerie, Cowen, Mara H., Lawlor, Mary-Kate, McCord, Mikayla, Xu, Hailey, Carmona, Esteban, Cheon, Seon-Hye, Chukwurah, Evelyn, Walla, Mike, Lizarraga, Sofia B.

Source: In Neurobiology of Disease August 2023 184

Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia

Authors: Park, Chun Shik, Yoshihara, Hiroki, Gao, Qingsong, Qu, Chunxu, Iacobucci, Ilaria, Ghate, Pankaj S., Connelly, Jon P., Pruett-Miller, Shondra M., Wagner, Ben, Robinson, Camenzind G., Mishra, Ashutosh, Peng, Junmin, Yang, Lei, Rankovic, Zoran, Finkelstein, David, Luger, Selina, Litzow, Mark, Paietta, Elisabeth M., Hebbar, Nikhil, Velasquez, M. Paulina, Mullighan, Charles G.

Source: In Cell Reports 25 July 2023 42(7)

The genomic basis of childhood T-lineage acute lymphoblastic leukaemia

Authors: Pölönen, Petri, Di Giacomo, Danika, Seffernick, Anna Eames, Elsayed, Abdelrahman, Kimura, Shunsuke, Benini, Francesca, Montefiori, Lindsey E., Wood, Brent L., Xu, Jason, Chen, Changya, Cheng, Zhongshan, Newman, Haley, Myers, Jason, Iacobucci, Ilaria, Li, Elizabeth, Sussman, Jonathan, Hedges, Dale, Hui, Yawei, Diorio, Caroline, Uppuluri, Lahari, Frank, David, Fan, Yiping, Chang, Yunchao, Meshinchi, Soheil, Ries, Rhonda, Shraim, Rawan, Li, Alexander, Bernt, Kathrin M., Devidas, Meenakshi, Winter, Stuart S., Dunsmore, Kimberly P., Inaba, Hiroto, Carroll, William L., Ramirez, Nilsa C., Phillips, Aaron H., Kriwacki, Richard W., Yang, Jun J., Vincent, Tiffaney L., Zhao, Yaqi, Ghate, Pankaj S., Wang, Jian, Reilly, Colleen, Zhou, Xin, Sanders, Mathijs A., Takita, Junko, Kato, Motohiro, Takasugi, Nao, Chang, Bill H., Press, Richard D., Loh, Mignon, Rampersaud, Evadnie, Raetz, Elizabeth, Hunger, Stephen P., Tan, Kai, Chang, Ti-Cheng, Wu, Gang, Pounds, Stanley B., Mullighan, Charles G., Teachey, David T.

Source: Nature; 20240101, Issue: Preprints p1-10, 10p

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Generation, annotation, and analysis of ESTs from midgut tissue of adult female Anopheles stephensi mosquitoes

Authors: Bhagwat Bhakti, Gupta Neha, Dayananda Kannayakanahalli M, Srivastav Abhishek, Ghate Pankaj S, Kulkarni Girish J, Chandode Rakesh K, Walujkar Sandeep A, Mahajan Vineet S, Anantharam D, Dhotre Dhiraj P, Atanur Santosh, Patil Deepak P, Joshi Rajendra R, Mourya Devendra T, Patole Milind S, Shouche Yogesh S

Source: BMC Genomics, Vol 10, Iss 1, p 386 (2009)

Subject Terms: Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.biomedcentral.com/1471-2164/10/386; https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/db996ace402b4de7a3b299258f23b284

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A Novel Anticancer Agent, 8-Methoxypyrimido[4′,5′:4,5]thieno(2,3-b) Quinoline-4(3H)-One Induces Neuro 2a Neuroblastoma Cell Death through p53-Dependent, Caspase-Dependent and -Independent Apoptotic Pathways.

Authors: Sahu, Upasana, Sidhar, Himakshi, Ghate, Pankaj S., Advirao, Gopal M., Raghavan, Sathees C., Giri, Ranjit K.

Source: PLoS ONE; Jun2013, Vol. 8 Issue 6, p1-18, 18p

Subject Terms: ANTINEOPLASTIC agents, QUINOLINE, NEUROBLASTOMA, CELL death, CASPASES, APOPTOSIS, CHILDHOOD cancer

Generation, annotation, and analysis of ESTs from midgut tissue of adult female Anopheles stephensi mosquitoes.

Authors: Patil, Deepak P., Atanur, Santosh, Dhotre, Dhiraj P., Anantharam, D., Mahajan, Vineet S., Walujkar, Sandeep A., Chandode, Rakesh K., Kulkarni, Girish J., Ghate, Pankaj S., Srivastav, Abhishek, Dayananda, Kannayakanahalli M., Gupta, Neha, Bhagwat, Bhakti, Joshi, Rajendra R., Mourya, Devendra T., Patole, Milind S., Shouche, Yogesh S.

Source: BMC Genomics; 2009, Vol. 10, p386-397, 12p, 6 Charts, 2 Graphs

Subject Terms: MOSQUITO genetics, GENOMES, GENES, GENE expression, GENETIC regulation