High immunoproteasome and low constitutive proteasome subunit levels correlate with sensitivity to bortezomib-containing chemotherapy: update from the Children’s Oncology Group AALL1231 trial

Authors: Margot S. F. Roeten, Johan van Meerloo, Suzanne N. van Dijk, Zinia Kwidama, Gaye Jenkins, David T. Teachey, Meenakshi Devidas, Mignon L. Loh, Gertjan J. L. Kaspers, Sonja Zweegman, Gerrit Jansen, Terzah M. Horton, Jacqueline Cloos

Source: Haematologica, Vol 999, Iss 1 (2025)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11922; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/790dae2aa02c4dd79da29d72a2a02093

Prehospital anesthesia in postcardiac arrest patients: a multicenter retrospective cohort study

Authors: Gerrit Jansen, Eugen Latka, Michael Bernhard, Martin Deicke, Daniel Fischer, Annika Hoyer, Yacin Keller, André Kobiella, Bernd Strickmann, Lisa Marie Strototte, Karl-Christian Thies, Kai Johanning

Source: European Journal of Medical Research, Vol 29, Iss 1, Pp 1-10 (2024)

Subject Terms: CPR, Emergency medicine, Resuscitation, Postarrest care, Management, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2047-783X

Access URL: https://doaj.org/article/1f6c2b4478724d5182c01a781fb04811

Effectiveness and safety of prehospital analgesia with nalbuphine and paracetamol versus morphine by paramedics - an observational study

Authors: Marvin Deslandes, Martin Deicke, Julia Johanna Grannemann, Jochen Hinkelbein, Annika Hoyer, Matthias Kalmbach, André Kobiella, Bernd Strickmann, Thomas Plappert, Gerrit Jansen

Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 32, Iss 1, Pp 1-8 (2024)

Subject Terms: Prehospital, Pain, Therapy, Emergency, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1757-7241

Access URL: https://doaj.org/article/09d60f42cd71463d9fb596e3cb542b64

Advancements in Public First Responder Programs for Out-of-Hospital Cardiac Arrest: An Updated Literature Review

Authors: Michael Kern, Gerrit Jansen, Bernd Strickmann, Thoralf Kerner

Source: Reviews in Cardiovascular Medicine, Vol 26, Iss 1, p 26140 (2025)

Subject Terms: out-of-hospital cardiac arrest, volunteer first responder, aed, smartphone alert, drones, covid-19, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM26140; https://doaj.org/toc/1530-6550

Access URL: https://doaj.org/article/75ef438220a040ebab31ffbc40dbd3c5

Unveiling the Anti-Angiogenic Potential of Small-Molecule (Kinase) Inhibitors for Application in Rheumatoid Arthritis

Authors: Fatemeh Khodadust, Eva M. L. Philippon, Maarten M. Steinz, Jan Piet van Hamburg, Johan van Meerloo, Judy R. van Beijnum, Gerrit Jansen, Sander W. Tas, Conny J. van der Laken

Source: Cells, Vol 14, Iss 2, p 102 (2025)

Subject Terms: angiogenesis, rheumatoid arthritis, 3D model, spheroid, small-molecule inhibitors, endothelial cells, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/14/2/102; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/8e4767acdf474081af07393acce6c5b2

The role of l-leucovorin uptake and metabolism in the modulation of 5-fluorouracil efficacy and antifolate toxicity

Authors: Godefridus J. Peters, Ietje Kathmann, Elisa Giovannetti, Kees Smid, Yehuda G. Assaraf, Gerrit Jansen

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: leucovorin stereo-isomers, l-leucovorin, thymidylate synthase, 5-fluorouracil, antifolates, pemetrexed, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1450418/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/f181d697131a47c99e405f990bc122f8

Enhancing prehospital analgesia – advantages and further indications of nalbuphin

Authors: Gerrit Jansen, Marvin Deslandes, Martin Deicke, Julia Johanna Grannemann, Annika Hoyer, Matthias Kalmbach, André Kobiella, Thomas Plappert, Bernd Strickmann, Jochen Hinkelbein

Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 32, Iss 1, Pp 1-2 (2024)

Subject Terms: Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1757-7241

Access URL: https://doaj.org/article/a196567d18244884a489f2a7ae848d36

Impact of COVID-19-adapted guidelines using different airway management strategies on resuscitation quality in out-of-hospital-cardiac-arrest – a randomised manikin study

Authors: Sean S. Scholz, Sissy Linder, Eugen Latka, Tobias Bartnick, Daniel Karla, Daniel Thaemel, Marlena Wolff, Odile Sauzet, Sebastian W. Rehberg, Karl-Christian Thies, Gerrit Jansen

Source: BMC Emergency Medicine, Vol 23, Iss 1, Pp 1-11 (2023)

Subject Terms: Aerosol liberation, CPR, Extraglottic airway, Supraglottic airway, Chest compression, Special situations and conditions, RC952-1245, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1471-227X

Access URL: https://doaj.org/article/3b5bdd22de44463cb5a732e6120dc6a8

GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate

Authors: Israel Ríos, Baltasar López-Navarro, Mónica Torres-Torresano, Blanca Soler Palacios, Miriam Simón-Fuentes, Ángeles Domínguez-Soto, Ittai B. Muller, Gerrit Jansen, Ángel L. Corbí, Amaya Puig-Kröger

Source: Journal of Innate Immunity, Pp 1-14 (2022)

Subject Terms: methotrexate, macrophages, macrophage reprogramming, Medicine, Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/526622; https://doaj.org/toc/1662-811X; https://doaj.org/toc/1662-8128

Access URL: https://doaj.org/article/2e2410ee239c488892b15234b443fcdb

P329: HIGH IMMUNOPROTEASOME ACTIVITY AS NOVEL INDICATOR FOR SENSITIVITY TO BORTEZOMIB-CONTAINING CHEMOTHERAPY IN ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS FROM CHILDREN’S ONCOLOGY GROUP TRIAL AALL1231

Authors: Margot Roeten, Suzanne van Dijk, Johan van Meerloo, Zinia Kwidama, Gaya Jenkins, David Teachey, Meenakshi Devidas, Mignon Loh, Gertjan Kaspers, Sonja Zweegman, Gerrit Jansen, Terzah Horton, Jacqueline Cloos

Source: HemaSphere, Vol 7, p e81299a0 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/01.HS9.0000968228.81299.a0; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/40d3b42d44514f25bb8ba0bffe07ecbd

Computational comparison of common event-based differential splicing tools: practical considerations for laboratory researchers

Authors: Ittai B. Muller, Stijn Meijers, Peter Kampstra, Steven van Dijk, Michel van Elswijk, Marry Lin, Anna M. Wojtuszkiewicz, Gerrit Jansen, Robert de Jonge, Jacqueline Cloos

Source: BMC Bioinformatics, Vol 22, Iss 1, Pp 1-15 (2021)

Subject Terms: Alternative splicing, RNA-sequencing, Computational performance, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/48488cd6dac8446990ad9680a93d0264

Mortality in septic patients treated with vitamin C: a systematic meta-analysis

Authors: Sean S. Scholz, Rainer Borgstedt, Nicole Ebeling, Leoni C. Menzel, Gerrit Jansen, Sebastian Rehberg

Source: Critical Care, Vol 25, Iss 1, Pp 1-10 (2021)

Subject Terms: Ascorbic acid, Septic shock, Mortality, Sepsis, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1364-8535

Access URL: https://doaj.org/article/09461b4f36aa40edb5b6f90cfc181701

Evolution and current state of global research on paediatric resuscitation: a systematic scientometric analysis

Authors: Sean S. Scholz, Rainer Borgstedt, Leoni C. Menzel, Sebastian Rehberg, Gerrit Jansen

Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 28, Iss 1, Pp 1-9 (2020)

Subject Terms: Cardiopulmonary resuscitation, Pediatric, Gender disparities, Critical care, Infant mortality, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13049-020-00780-3; https://doaj.org/toc/1757-7241

Access URL: https://doaj.org/article/8de2f7cef6b44fb492bf44f70f557ca1

Validation of a Prognostic Multivariable Prediction Model for Insufficient Clinical Response to Methotrexate in Early Rheumatoid Arthritis and Its Clinical Application in Evidencio

Authors: Helen R. Gosselt, Maxime M. A. Verhoeven, Maurits C. F. J. de Rotte, Saskia M. F. Pluijm, Ittai B. Muller, Gerrit Jansen, Janneke Tekstra, Maja Bulatović-Ćalasan, Sandra G. Heil, Floris P. J. G. Lafeber, Johanna M. W. Hazes, Robert de Jonge

Source: Rheumatology and Therapy, Vol 7, Iss 4, Pp 837-850 (2020)

Subject Terms: Arthritis, Health care, Methotrexate, Outcome assessment, Rheumatoid, Therapeutics, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/2198-6576; https://doaj.org/toc/2198-6584

Access URL: https://doaj.org/article/30416e6757fd4ef68ed9fc2301287f9b

Activation of LXR Nuclear Receptors Impairs the Anti-Inflammatory Gene and Functional Profile of M-CSF-Dependent Human Monocyte-Derived Macrophages

Authors: Arturo González de la Aleja, Cristina Herrero, Mónica Torres-Torresano, Juan Vladimir de la Rosa, Bárbara Alonso, Enrique Capa-Sardón, Ittai B. Muller, Gerrit Jansen, Amaya Puig-Kröger, Miguel A. Vega, Antonio Castrillo, Ángel L. Corbí

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: innate immunity, macrophage, macrophage polarization, LXR, inflammation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.835478/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/74a9cd2489134bd39bba68edb1a38025

Folate Receptor Beta for Macrophage Imaging in Rheumatoid Arthritis

Authors: Maarten M. Steinz, Aiarpi Ezdoglian, Fatemeh Khodadust, Carla F. M. Molthoff, Madduri Srinivasarao, Philip S. Low, Gerben J. C. Zwezerijnen, Maqsood Yaqub, Wissam Beaino, Albert D. Windhorst, Sander W. Tas, Gerrit Jansen, Conny J. van der Laken

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: PET imaging, folate receptor beta, rheumatoid arthritis, macrophage, antigen-induced arthritis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.819163/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/029857162ef5491a9e59a32e5a1d6081

The Macrophage Reprogramming Ability of Antifolates Reveals Soluble CD14 as a Potential Biomarker for Methotrexate Response in Rheumatoid Arthritis

Authors: Sara Fuentelsaz-Romero, Celia Barrio-Alonso, Raquel García Campos, Mónica Torres Torresano, Ittai B. Muller, Ana Triguero-Martínez, Laura Nuño, Alejandro Villalba, Rosario García-Vicuña, Gerrit Jansen, María-Eugenia Miranda-Carús, Isidoro González-Álvaro, Amaya Puig-Kröger

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: macrophages, methotrexate, pemetrexed, sCD14, predictor biomarker, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.776879/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/0c17ff55e2564e3295c528665d899119

Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis

Authors: Yingwen Hu, Bingbing Wang, Jiayin Shen, Stewart A. Low, Karson S. Putt, Hans W. M. Niessen, Eric L. Matteson, Linda Murphy, Clemens Ruppert, Gerrit Jansen, Stephen J. Oliver, Yang Feng, Dimiter S. Dimitrov, Cheryl Nickerson-Nutter, Philip S. Low

Source: Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)

Subject Terms: Folate receptor beta, Activated macrophages, Inflammatory disease, Autoimmune disease, Rheumatoid arthritis, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13075-019-1912-0; https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/1dc2d4681dd3423db7d7c71fbd322d51

Schedule-Dependent Synergy Between the Histone Deacetylase Inhibitor Belinostat and the Dihydrofolate Reductase Inhibitor Pralatrexate in T-and B-cell Lymphoma Cells in vitro

Authors: Godefridus J. Peters, Frank P. A. van Gemert, Ietje Kathmann, Guru Reddy, Saskia A. G. M. Cillessen, Gerrit Jansen

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Subject Terms: antifolates, pralatrexate, histone deacetylase inhibitors, belinostat, peripheral T-cell lymphoma, diffuse B-cell lymphoma, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fcell.2020.577215/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/3e3291e8ac454216bc476996dc1f37dc

Folate receptors and transporters: biological role and diagnostic/therapeutic targets in cancer and other diseases

Authors: Barbara Frigerio, Claudia Bizzoni, Gerrit Jansen, Christopher P. Leamon, Godefridus J. Peters, Philip S. Low, Larry H. Matherly, Mariangela Figini

Source: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)

Subject Terms: Folate, Folate receptors, Folate transporters, Cancer targeting, Inflammation targeting, One-carbon metabolism, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13046-019-1123-1; https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/f4b18e0bfe5141bba02c239297005075