A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

Authors: Hunter, David J, Kraft, Peter, Jacobs, Kevin B, Cox, David G, Yeager, Meredith, Hankinson, Susan E, Wacholder, Sholom, Wang, Zhaoming, Welch, Robert, Hutchinson, Amy, Wang, Junwen, Yu, Kai, Chatterjee, Nilanjan, Orr, Nick, Willett, Walter C, Colditz, Graham A, Ziegler, Regina G, Berg, Christine D, Buys, Saundra S, McCarty, Catherine A, Feigelson, Heather Spencer, Calle, Eugenia E, Thun, Michael J, Hayes, Richard B, Tucker, Margaret, Gerhard, Daniela S, Fraumeni, Joseph F, Jr, Hoover, Robert N, Thomas, Gilles, Chanock, Stephen J

Source: Hunter, David J and Kraft, Peter and Jacobs, Kevin B and Cox, David G and Yeager, Meredith and Hankinson, Susan E and Wacholder, Sholom and Wang, Zhaoming and Welch, Robert and Hutchinson, Amy and Wang, Junwen and Yu, Kai and Chatterjee, Nilanjan and Orr, Nick and Willett, Walter C and Colditz, Graham A and Ziegler, Regina G and Berg, Christine D and Buys, Saundra S and McCarty, Catherine A and Feigelson, Heather Spencer and Calle, Eugenia E and Thun, Michael J and Hayes, Richard B and Tucker, Margaret and Gerhard, Daniela S and Fraumeni, Joseph F, Jr and Hoover, Robert N and Thomas, Gilles and Chanock, Stephen J (2007) A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nature Genetics, 39. pp. 870-874.

Relation: http://www.nature.com/ng/journal/v39/n7/full/ng2075.html; http://health-equity.pitt.edu/706/

Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma

Authors: Thomas, Nicole, Dreval, Kostiantyn, Gerhard, Daniela S., Hilton, Laura K., Abramson, Jeremy S., Ambinder, Richard F., Barta, Stefan, Bartlett, Nancy L., Bethony, Jeffrey, Bhatia, Kishor, Bowen, Jay, Bryan, Anthony C., Cesarman, Ethel, Casper, Corey, Chadburn, Amy, Cruz, Manuela, Dittmer, Dirk P., Dyer, Maureen A., Farinha, Pedro, Gastier-Foster, Julie M., Gerrie, Alina S., Grande, Bruno M., Greiner, Timothy, Griner, Nicholas B., Gross, Thomas G., Harris, Nancy L., Irvin, John D., Jaffe, Elaine S., Henry, David, Huppi, Rebecca, Leal, Fabio E., Lee, Michael S., Martin, Jean Paul, Martin, Marie-Reine, Mbulaiteye, Sam M., Mitsuyasu, Ronald, Morris, Vivian, Mullighan, Charles G., Mungall, Andrew J., Mungall, Karen, Mutyaba, Innocent, Nokta, Mostafa, Namirembe, Constance, Noy, Ariela, Ogwang, Martin D., Omoding, Abraham, Orem, Jackson, Ott, German, Petrello, Hilary, Pittaluga, Stefania, Phelan, James D., Ramos, Juan Carlos, Ratner, Lee, Reynolds, Steven J., Rubinstein, Paul G., Sissolak, Gerhard, Slack, Graham, Soudi, Shaghayegh, Swerdlow, Steven H., Traverse-Glehen, Alexandra, Wilson, Wyndham H., Wong, Jasper, Yarchoan, Robert, ZenKlusen, Jean C., Marra, Marco A., Staudt, Louis M., Scott, David W., Morin, Ryan D.

Source: In Blood 23 February 2023 141(8):904-916

An expanded universe of cancer targets

Authors: Dancik, Vlado, Gill, Shubhroz, Hua, Bruce, Sharifnia, Tanaz, Viswanathan, Vasanthi, Zou, Yilong, Dela Cruz, Filemon, Kung, Andrew, Stockwell, Brent, Boehm, Jesse, Dempster, Josh, Manguso, Robert, Vazquez, Francisca, Cooper, Lee A.D., Du, Yuhong, Ivanov, Andrey, Lonial, Sagar, Moreno, Carlos S., Niu, Qiankun, Owonikoko, Taofeek, Ramalingam, Suresh, Reyna, Matthew, Zhou, Wei, Grandori, Carla, Shmulevich, Ilya, Swisher, Elizabeth, Cai, Jitong, Chan, Issac S., Dunworth, Matthew, Ge, Yuchen, Georgess, Dan, Grasset, Eloïse M., Henriet, Elodie, Knútsdóttir, Hildur, Lerner, Michael G., Padmanaban, Veena, Perrone, Matthew C., Suhail, Yasir, Tsehay, Yohannes, Warrier, Manisha, Morrow, Quin, Nechiporuk, Tamilla, Long, Nicola, Saultz, Jennifer, Kaempf, Andy, Minnier, Jessica, Tognon, Cristina E., Kurtz, Stephen E., Agarwal, Anupriya, Brown, Jordana, Watanabe-Smith, Kevin, Vu, Tania Q., Jacob, Thomas, Yan, Yunqi, Robinson, Bridget, Lind, Evan F., Kosaka, Yoko, Demir, Emek, Estabrook, Joseph, Grzadkowski, Michael, Nikolova, Olga, Chen, Ken, Deneen, Ben, Liang, Han, Bassik, Michael C., Bhattacharya, Asmita, Brennan, Kevin, Curtis, Christina, Gevaert, Olivier, Ji, Hanlee P., Karlsson, Kasper A.J., Karagyozova, Kremena, Lo, Yuan-Hung, Liu, Katherine, Nakano, Michitaka, Sathe, Anuja, Smith, Amber R., Spees, Kaitlyn, Wong, Wing Hing, Yuki, Kanako, Hangauer, Matt, Kaufman, Dan S., Balmain, Allan, Bollam, Saumya R., Chen, Wei-Ching, Fan, QiWen, Kersten, Kelly, Krummel, Matthew, Li, Yun Rose, Menard, Marie, Nasholm, Nicole, Schmidt, Christin, Serwas, Nina K., Yoda, Hiroyuki, Ashworth, Alan, Bandyopadhyay, Sourav, Bivona, Trevor, Eades, Gabriel, Oberlin, Stefan, Tay, Neil, Wang, Yuhao, Weissman, Jonathan, Hahn, William C., Bader, Joel S., Braun, Theodore P., Califano, Andrea, Clemons, Paul A., Druker, Brian J., Ewald, Andrew J., Fu, Haian, Jagu, Subhashini, Kemp, Christopher J., Kim, William, Kuo, Calvin J., McManus, Michael T., B. Mills, Gordon, Mo, Xiulei, Sahni, Nidhi, Schreiber, Stuart L., Talamas, Jessica A., Tamayo, Pablo, Tyner, Jeffrey W., Wagner, Bridget K., Weiss, William A., Gerhard, Daniela S.

Source: In Cell 4 March 2021 184(5):1142-1155

Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration

Authors: Chun, Hye-Jung E., Johann, Pascal D., Milne, Katy, Zapatka, Marc, Buellesbach, Annette, Ishaque, Naveed, Iskar, Murat, Erkek, Serap, Wei, Lisa, Tessier-Cloutier, Basile, Lever, Jake, Titmuss, Emma, Topham, James T., Bowlby, Reanne, Chuah, Eric, Mungall, Karen L., Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Taylor, Michael D., Gerhard, Daniela S., Jones, Steven J.M., Korshunov, Andrey, Gessler, Manfred, Kerl, Kornelius, Hasselblatt, Martin, Frühwald, Michael C., Perlman, Elizabeth J., Nelson, Brad H., Pfister, Stefan M., Marra, Marco A., Kool, Marcel

Source: In Cell Reports 19 November 2019 29(8):2338-2354

Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons’ Data

Authors: Gao, Galen F., Parker, Joel S., Reynolds, Sheila M., Silva, Tiago C., Wang, Liang-Bo, Zhou, Wanding, Akbani, Rehan, Bailey, Matthew, Balu, Saianand, Berman, Benjamin P., Brooks, Denise, Chen, Hu, Cherniack, Andrew D., Demchok, John A., Ding, Li, Felau, Ina, Gaheen, Sharon, Gerhard, Daniela S., Heiman, David I., Hernandez, Kyle M., Hoadley, Katherine A., Jayasinghe, Reyka, Kemal, Anab, Knijnenburg, Theo A., Laird, Peter W., Mensah, Michael K.A., Mungall, Andrew J., Robertson, A. Gordon, Shen, Hui, Tarnuzzer, Roy, Wang, Zhining, Wyczalkowski, Matthew, Yang, Liming, Zenklusen, Jean C., Zhang, Zhenyu, Liang, Han, Noble, Michael S.

Source: In Cell Systems 24 July 2019 9(1):24-34

Genome-wide discovery of somatic coding and noncoding mutations in pediatric endemic and sporadic Burkitt lymphoma

Authors: Grande, Bruno M. ^*, Gerhard, Daniela S. ^*, Jiang, Aixiang, Griner, Nicholas B., Abramson, Jeremy S., Alexander, Thomas B., Allen, Hilary, Ayers, Leona W., Bethony, Jeffrey M., Bhatia, Kishor, Bowen, Jay, Casper, Corey, Choi, John Kim, Culibrk, Luka, Davidsen, Tanja M., Dyer, Maureen A., Gastier-Foster, Julie M., Gesuwan, Patee, Greiner, Timothy C., Gross, Thomas G., Hanf, Benjamin, Harris, Nancy Lee, He, Yiwen, Irvin, John D., Jaffe, Elaine S., Jones, Steven J.M., Kerchan, Patrick, Knoetze, Nicole, Leal, Fabio E., Lichtenberg, Tara M., Ma, Yussanne, Martin, Jean Paul, Martin, Marie-Reine, Mbulaiteye, Sam M., Mullighan, Charles G., Mungall, Andrew J., Namirembe, Constance, Novik, Karen, Noy, Ariela, Ogwang, Martin D., Omoding, Abraham, Orem, Jackson, Reynolds, Steven J., Rushton, Christopher K., Sandlund, John T., Schmitz, Roland, Taylor, Cynthia, Wilson, Wyndham H., Wright, George W., Zhao, Eric Y., Marra, Marco A., Morin, Ryan D. ^*, Staudt, Louis M. ^**

Source: In Blood 21 March 2019 133(12):1313-1324

A Mouse Atlas of Gene Expression: Large-Scale Digital Gene-Expression Profiles from Precisely Defined Developing C57BL/6J Mouse Tissues and Cells

Authors: Khattra, Jaswinder, Barber, Sarah, Gerhard, Daniela S., Holt, Robert A., Mayo, Michael, McDonald, Helen, Riggins, Gregory J., Wong, David, Hirst, Martin, Helgason, Cheryl D., Simpson, Elizabeth M., Marra, Marco A., Waterston, Robert H.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2005 Dec . 102(51), 18485-18490.

Access URL: https://www.jstor.org/stable/4152643

Transcriptional Maps of 10 Human Chromosomes at 5-Nucleotide Resolution

Authors: Cheng, Jill, Kapranov, Philipp, Drenkow, Jorg, Dike, Sujit, Brubaker, Shane, Patel, Sandeep, Long, Jeffrey, Stern, David, Tammana, Hari, Helt, Gregg, Sementchenko, Victor, Piccolboni, Antonio, Bekiranov, Stefan, Bailey, Dione K., Ganesh, Madhavan, Ghosh, Srinka, Bell, Ian, Gerhard, Daniela S., Gingeras, Thomas R.

Source: Science, 2005 May . 308(5725), 1149-1154.

Access URL: https://www.jstor.org/stable/3842098

A High-Resolution Physical Map of Human Chromosome 11

Authors: Qin, Shizhen, Nowak, Norma J., Zhang, Jialu, Mayers, Peter G., Higgins, Michael J., Cheng, Yi-Jun, Munroe, David J., Gerhard, Daniela S., Weber, Bernhard H., Bric, Eva, Housman, David E., Evans, Glen A., Shows, Thomas B.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1996 Apr 01. 93(7), 3149-3154.

Access URL: https://www.jstor.org/stable/39131

Genome-Wide Profiles of Extra-cranial Malignant Rhabdoid Tumors Reveal Heterogeneity and Dysregulated Developmental Pathways

Authors: Chun, Hye-Jung E., Lim, Emilia L., Heravi-Moussavi, Alireza, Saberi, Saeed, Mungall, Karen L., Bilenky, Mikhail, Carles, Annaick, Tse, Kane, Shlafman, Inna, Zhu, Kelsey, Qian, Jenny Q., Palmquist, Diana L., He, An, Long, William, Goya, Rodrigo, Ng, Michelle, LeBlanc, Veronique G., Pleasance, Erin, Thiessen, Nina, Wong, Tina, Chuah, Eric, Zhao, Yong-Jun, Schein, Jacquie E., Gerhard, Daniela S., Taylor, Michael D., Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Jones, Steven J.M., Perlman, Elizabeth J., Hirst, Martin, Marra, Marco A.

Source: In Cancer Cell 14 March 2016 29(3):394-406

Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors

Authors: Walz, Amy L., Ooms, Ariadne, Gadd, Samantha, Gerhard, Daniela S., Smith, Malcolm A., Guidry Auvil, Jaime M., Meerzaman, Daoud, Chen, Qing-Rong, Hsu, Chih Hao, Yan, Chunhua, Nguyen, Cu, Hu, Ying, Bowlby, Reanne, Brooks, Denise, Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Schein, Jacqueline, Marra, Marco A., Huff, Vicki, Dome, Jeffrey S., Chi, Yueh-Yun, Mullighan, Charles G., Ma, Jing, Wheeler, David A., Hampton, Oliver A., Jafari, Nadereh, Ross, Nicole, Gastier-Foster, Julie M., Perlman, Elizabeth J.

Source: In Cancer Cell 9 February 2015 27(2):286-297

A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults

Authors: Perez-Andreu, Virginia, Roberts, Kathryn G., Xu, Heng, Smith, Colton, Zhang, Hui, Yang, Wenjian, Harvey, Richard C., Payne-Turner, Debbie, Devidas, Meenakshi, Cheng, I-Ming, Carroll, William L., Heerema, Nyla A., Carroll, Andrew J., Raetz, Elizabeth A., Gastier-Foster, Julie M., Marcucci, Guido, Bloomfield, Clara D., Mrózek, Krzysztof, Kohlschmidt, Jessica, Stock, Wendy, Kornblau, Steven M., Konopleva, Marina, Paietta, Elisabeth, Rowe, Jacob M., Luger, Selina M., Tallman, Martin S., Dean, Michael, Burchard, Esteban G., Torgerson, Dara G., Yue, Feng, Wang, Yanli, Pui, Ching-Hon, Jeha, Sima, Relling, Mary V., Evans, William E., Gerhard, Daniela S., Loh, Mignon L., Willman, Cheryl L., Hunger, Stephen P., Mullighan, Charles G. ^*, Yang, Jun J. ^*

Source: In Blood 22 January 2015 125(4):680-686

Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival.

Authors: Kim, Jung, Vaksman, Zalman, Egolf, Laura E, Kaufman, Rebecca, Evans, J Perry, Conkrite, Karina L, Danesh, Arnavaz, Lopez, Gonzalo, Randall, Michael P, Dent, Maiah H, Farra, Lance M, Menghani, Neil L, Dymek, Malwina, Desai, Heena, Hausler, Ryan, Hicks, Belynda, Auvil, Jaime Guidry, Gerhard, Daniela S, Hakonarson, Hakon, Maxwell, Kara N

Source: JNCI: Journal of the National Cancer Institute; Jan2024, Vol. 116 Issue 1, p149-159, 11p

Subject Terms: NEUROBLASTOMA, GERM cells, DNA copy number variations, NEURAL development, SYMPATHETIC nervous system, CANCER genes

DNA Methylation-Based Burkitt Lymphoma Epitypes Have Distinct Molecular and Clinical Features

Authors: Thomas, Nicole ^*, Dreval, Kostiantyn ^*, Gerhard, Daniela S. ^*, Hilton, Laura K ^*, Abramson, Jeremy S., Bartlett, Nancy L., Bethony, Jeffrey ^*, Bowen, Jay ^*, Bryan, Anthony ^*, Casper, Corey ^*, Dyer, Maureen ^*, Esteller, Manel ^*, Garcia-Prieto, Carlos ^*, Gastier-Foster, Julie M, Gerrie, Alina S., Grande, Bruno M. ^*, Greiner, Timothy C., Griner, Nicholas B. ^*, Gross, Thomas G., Harris, Nancy Lee, Irvin, John D. ^*, Jaffe, Elaine S., Leal, Fabio ^*, Martin, Jean Paul ^*, Martin, Marie-Reine ^*, Mbulaiteye, Sam M. ^*, Mullighan, Charles G., Mungall, Andrew J. ^*, Mungall, Karen ^*, Namirembe, Constance ^*, Noy, Ariela, Ogwang, Martin D ^*, Orem, Jackson, Ott, German ^*, Petrello, Hilary ^*, Reynolds, Steven J ^*, Swerdlow, Steven H., Traverse-Glehen, Alexandra ^*, Wilson, Wyndham H., Marra, Marco A., Staudt, Louis M., Scott, David W., Morin, Ryan D.

Source: In Blood 15 November 2022 140 Supplement 1:1734-1736

Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia

Authors: Roberts, Kathryn G., Morin, Ryan D., Zhang, Jinghui, Hirst, Martin, Zhao, Yongjun, Su, Xiaoping, Chen, Shann-Ching, Payne-Turner, Debbie, Churchman, Michelle L., Harvey, Richard C., Chen, Xiang, Kasap, Corynn, Yan, Chunhua, Becksfort, Jared, Finney, Richard P., Teachey, David T., Maude, Shannon L., Tse, Kane, Moore, Richard, Jones, Steven, Mungall, Karen, Birol, Inanc, Edmonson, Michael N., Hu, Ying, Buetow, Kenneth E., Chen, I-Ming, Carroll, William L., Wei, Lei, Ma, Jing, Kleppe, Maria, Levine, Ross L., Garcia-Manero, Guillermo, Larsen, Eric, Shah, Neil P., Devidas, Meenakshi, Reaman, Gregory, Smith, Malcolm, Paugh, Steven W., Evans, William E., Grupp, Stephan A., Jeha, Sima, Pui, Ching-Hon, Gerhard, Daniela S., Downing, James R., Willman, Cheryl L., Loh, Mignon, Hunger, Stephen P., Marra, Marco A., Mullighan, Charles G.

Source: In Cancer Cell 14 August 2012 22(2):153-166

The Genetic Landscape of the Childhood Cancer Medulloblastoma

Authors: Parsons, D. Williams, Li, Meng, Zhang, Xiaosong, Jones, Siân, Leary, Rebecca J., Lin, Jimmy Cheng-Ho, Boca, Simina M., Carter, Hannah, Samayoa, Josue, Bettegowda, Chetan, Gallia, Gary L., Jallo, George I., Binder, Zev A., Nikolsky, Yuri, Hartigan, James, Smith, Doug R., Gerhard, Daniela S., Fults, Daniel W., VandenBerg, Scott, Berger, Mitchel S., Marie, Suely Kazue Nagahashi, Shinjo, Sueli Mieko Oba, Clara, Carlos, Phillips, Peter C., Minturn, Jane E., Biegel, Jaclyn A., Judkins, Alexander R., Resnick, Adam C., Storm, Phillip B., Curran, Tom, He, Yiping, Rasheed, B. Ahmed, Friedman, Henry S., Keir, Stephen T., McLendon, Roger, Northcott, Paul A., Taylor, Michael D., Burger, Peter C., Riggins, Gregory J., Karchin, Rachel, Parmigiani, Giovanni, Bigner, Darell D., Yan, Hai, Papadopoulos, Nick, Vogelstein, Bert, Kinzler, Kenneth W., Velculescu, Victor E.

Source: Science, 2011 Jan . 331(6016), 435-439.

Access URL: http://dx.doi.org/10.1126/science.1198056

The Genome of the Western Clawed Frog Xenopus tropicalis

Authors: Hellsten, Uffe, Harland, Richard M., Gilchrist, Michael J., Hendrix, David, Jurka, Jerzy, Kapitonov, Vladimir, Ovcharenko, Ivan, Putnam, Nicholas H., Shu, Shengqiang, Taher, Leila, Blitz, Ira L., Blumberg, Bruce, Dichmann, Darwin S., Dubchak, Inna, Amaya, Enrique, Detter, John C., Fletcher, Russell, Gerhard, Daniela S., Goodstein, David, Graves, Tina, Grigoriev, Igor V., Grimwood, Jane, Kawashima, Takeshi, Lindquist, Erika, Lucas, Susan M., Mead, Paul E., Mitras, Therese, Ogino, Hajime, Ohta, Yuko, Poliakov, Alexander V., Pollet, Nicolas, Robert, Jacques, Salamov, Asaf, Sater, Amy K., Schmutz, Jeremy, Terry, Astrid, Vize, Peter D., Warren, Wesley C., Wells, Dan, Wills, Andrea, Wilson, Richard K., Zimmerman, Lyle B., Zorn, Aaron M., Grainger, Robert, Grammer, Timothy, Khokha, Mustafa K., Richardson, Paul M., Rokhsar, Daniel S.

Source: Science, 2010 Apr . 328(5978), 633-636.

Access URL: https://www.jstor.org/stable/40655841

JAK Mutations in High-Risk Childhood Acute Lymphoblastic Leukemia

Authors: Mullighan, Charles G., Zhang, Jinghui, Harvey, Richard C., Collins-Underwood, J. Racquel, Schulman, Brenda A., Phillips, Letha A., Tasian, Sarah K., Loh, Mignon L., Su, Xiaoping, Liu, Wei, Devidas, Meenakshi, Atlas, Susan R., Chen, I-Ming, Clifford, Robert J., Gerhard, Daniela S., Carroll, William L., Reaman, Gregory H., Smith, Malcolm, Downing, James R., Hunger, Stephen P., Willman, Cheryl L., Rowley, Janet D.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2009 Jun 01. 106(23), 9414-9418.

Access URL: https://www.jstor.org/stable/40483229

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group

Authors: Zhang, Jinghui ^*, Mullighan, Charles G. ^*, Harvey, Richard C., Wu, Gang, Chen, Xiang, Edmonson, Michael, Buetow, Kenneth H., Carroll, William L., Chen, I-Ming, Devidas, Meenakshi, Gerhard, Daniela S., Loh, Mignon L., Reaman, Gregory H., Relling, Mary V., Camitta, Bruce M., Bowman, W. Paul, Smith, Malcolm A., Willman, Cheryl L., Downing, James R., Hunger, Stephen P.

Source: In Blood 15 September 2011 118(11):3080-3087

Identification of a Recent Recombination Event within the Human β -globin Gene Cluster

Authors: Gerhard, Daniela S., Kidd, Kenneth K., Kidd, Judith R., Egeland, Janice A., Housman, David E.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1984 Dec . 81(24), 7875-7879.

Access URL: https://www.jstor.org/stable/24443