5-Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapy

Authors: Masao Fukumura, Naosuke Nonoguchi, Shinji Kawabata, Ryo Hiramatsu, Gen Futamura, Koji Takeuchi, Takuya Kanemitsu, Takushi Takata, Hiroki Tanaka, Minoru Suzuki, Oltea Sampetrean, Naokado Ikeda, Toshihiko Kuroiwa, Hideyuki Saya, Ichiro Nakano, Masahiko Wanibuchi

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/4606578ef6c3434ea625581fa0014279

Efficacy of Boron Neutron Capture Therapy in Primary Central Nervous System Lymphoma: In Vitro and In Vivo Evaluation

Authors: Kohei Yoshimura, Shinji Kawabata, Hideki Kashiwagi, Yusuke Fukuo, Koji Takeuchi, Gen Futamura, Ryo Hiramatsu, Takushi Takata, Hiroki Tanaka, Tsubasa Watanabe, Minoru Suzuki, Naonori Hu, Shin-Ichi Miyatake, Masahiko Wanibuchi

Source: Cells, Vol 10, Iss 12, p 3398 (2021)

Subject Terms: boron neutron capture therapy (BNCT), malignant brain tumor, primary central nervous system lymphoma (PCNSL), radiation therapy, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/12/3398; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/e995583d3cec4ad3b931fd49e4cea653

The Therapeutic Effects of Dodecaborate Containing Boronophenylalanine for Boron Neutron Capture Therapy in a Rat Brain Tumor Model

Authors: Yusuke Fukuo, Yoshihide Hattori, Shinji Kawabata, Hideki Kashiwagi, Takuya Kanemitsu, Koji Takeuchi, Gen Futamura, Ryo Hiramatsu, Tsubasa Watanabe, Naonori Hu, Takushi Takata, Hiroki Tanaka, Minoru Suzuki, Shin-Ichi Miyatake, Mitsunori Kirihata, Masahiko Wanibuchi

Source: Biology, Vol 9, Iss 12, p 437 (2020)

Subject Terms: boron neutron capture therapy (BNCT), malignant glioma, survival prolongation, boronophenylalanine–amide alkyl dodecaborate (BADB), Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2079-7737/9/12/437; https://doaj.org/toc/2079-7737

Access URL: https://doaj.org/article/6032a14f3f784825b7d76a81461a3189

Synthesis and Evaluation of Dodecaboranethiol Containing Kojic Acid (KA-BSH) as a Novel Agent for Boron Neutron Capture Therapy

Authors: Koji Takeuchi, Yoshihide Hattori, Shinji Kawabata, Gen Futamura, Ryo Hiramatsu, Masahiko Wanibuchi, Hiroki Tanaka, Shin-ichiro Masunaga, Koji Ono, Shin-Ichi Miyatake, Mitsunori Kirihata

Source: Cells, Vol 9, Iss 6, p 1551 (2020)

Subject Terms: boron neutron capture therapy (BNCT), F98 rat glioma model, kojic acid, boron compound, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/6/1551; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/9ad46844f331468b87ffb73bbbf9084b

Two reports of iatrogenic pseudoaneurysms intraoperatively induced by an ultrasonic surgical aspirator: A rare intraoperative complication.

Authors: Hirokuni Hashikata, Yasunori Nagai, Gen Futamura, Naokado Ikeda, Masanori Goto, Yoshinori Maki, Hiroki Toda, Koichi Iwasaki

Source: Surgical Neurology International; 2024, Vol. 15, p1-6, 6p

Subject Terms: BASILAR artery, INTRACRANIAL tumors, ASPIRATORS, SUBARACHNOID hemorrhage, SURGICAL complications, CRANIOPHARYNGIOMA, FALSE aneurysms, CEREBRAL angiography

Evaluation of a novel sodium borocaptate-containing unnatural amino acid as a boron delivery agent for neutron capture therapy of the F98 rat glioma.

Authors: Gen Futamura¹, Shinji Kawabata¹ neu046@osaka-med.ac.jp, Naosuke Nonoguchi¹, Ryo Hiramatsu¹, Taichiro Toho¹, Hiroki Tanaka², Shin-Ichiro Masunaga², Yoshihide Hattori³, Mitsunori Kirihata³, Koji Ono², Toshihiko Kuroiwa¹, Shin-Ichi Miyatake⁴, Futamura, Gen¹ (AUTHOR), Kawabata, Shinji¹ (AUTHOR), Nonoguchi, Naosuke¹ (AUTHOR), Hiramatsu, Ryo¹ (AUTHOR), Toho, Taichiro¹ (AUTHOR), Tanaka, Hiroki² (AUTHOR), Masunaga, Shin-Ichiro² (AUTHOR), Hattori, Yoshihide³ (AUTHOR)

Source: Radiation Oncology. 1/23/2017, Vol. 12, p1-11. 11p.

Subject Terms: *GLIOMA treatment, *BORON, *BORON-neutron capture therapy, *THERAPEUTIC use of boron isotopes, *CANCER radiotherapy, *THERAPEUTICS, *ANIMAL experimentation, *BLOOD-brain barrier, *BORON compounds, *BRAIN tumors, *COMPARATIVE studies, *DRUG delivery systems, *GLIOMAS, *RESEARCH methodology, *MEDICAL cooperation, *RADIOTHERAPY, *RATS, *RESEARCH, *SULFUR compounds, *EVALUATION research, *CANCER cell culture

A case of radiation-induced osteosarcoma treated effectively by boron neutron capture therapy.

Authors: Gen Futamura¹ neu130@poh.osaka-med.ac.jp, Shinji Kawabata¹ neu046@poh.osaka-med.ac.jp, Hiroyuki Siba¹ shibatti_nimitz@yahoo.co.jp, Toshihiko Kuroiwa¹ neu040@poh.osaka-med.ac.jp, Minoru Suzuki² msuzuki@rri.kyoto-u.ac.jp, Natsuko Kondo² nkondo@rri.kyoto-u.ac.jp, Koji Ono² onokoji@rri.kyoto-u.ac.jp, Yoshinori Sakurai³ yosakura@rri.kyoto-u.ac.jp, Minoru Tanaka⁴ mntanaka-neu@umin.ac.jp, Tomoki Todo⁴ toudou-nsu@umin.ac.jp, Shin-Ichi Miyatake⁵ neu070@poh.osaka-med.ac.jp

Source: Radiation Oncology. 2014, Vol. 9 Issue 1, p1-11. 11p.

Subject Terms: *OSTEOSARCOMA, *BORON-neutron capture therapy, *RADIOTHERAPY, *CEREBELLAR ataxia, *RADIATION damage, *THERAPEUTICS