Heterogeneity of ferrous iron‐containing endolysosomes and effects of endolysosome iron on endolysosome numbers, sizes, and localization patterns

Authors: Halcrow, Peter W., Kumar, Nirmal, Afghah, Zahra, Fischer, Jalyn P., Khan, Nabab, Chen, Xuesong, Meucci, Olimpia, Geiger, Jonathan D.

Source: Journal of neurochemistry. 161(1):69-83

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Role of endolysosome function in iron metabolism and brain carcinogenesis

Authors: Halcrow, Peter W., Lynch, Miranda L., Geiger, Jonathan D., Ohm, Joyce E. ^*

Source: In Seminars in Cancer Biology November 2021 76:74-85

A common approach for fighting tuberculosis and leprosy: controlling endoplasmic reticulum stress in myeloid-derived suppressor cells

Authors: Kumar, Nirmal, Khan, Nabab, Cleveland, Dawn, Geiger, Jonathan D

Source: Immunotherapy. 13(18):1555-1563

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191698291.0x000001&indx=1&recIds=ETOCvdc_100191698291.0x000001

Janus sword actions of chloroquine and hydroxychloroquine against COVID-19

Authors: Chen, Xuesong, Geiger, Jonathan D.

Source: In Cellular Signalling September 2020 73

Bioenergetic adaptations to HIV infection. Could modulation of energy substrate utilization improve brain health in people living with HIV-1?

Authors: Deme, Pragney, Rojas, Camilo, Slusher, Barbara S., Rais, Raina, Afghah, Zahra, Geiger, Jonathan D., Haughey, Norman J.

Source: In Experimental Neurology May 2020 327

Role of endolysosomes and inter-organellar signaling in brain disease

Authors: Afghah, Zahra, Chen, Xuesong, Geiger, Jonathan D.

Source: In Neurobiology of Disease February 2020 134

Circulating levels of ATP is a biomarker of HIV cognitive impairment

Authors: Velasquez, Stephani, Prevedel, Lisa, Valdebenito, Silvana, Gorska, Anna Maria, Golovko, Mikhail, Khan, Nabab, Geiger, Jonathan, Eugenin, Eliseo A.

Source: In EBioMedicine January 2020 51

Involvement of organelles and inter-organellar signaling in the pathogenesis of HIV-1 associated neurocognitive disorder and Alzheimer’s disease

Authors: Khan, Nabab, Haughey, Norman J., Nath, Avindra, Geiger, Jonathan D.

Source: In Brain Research 1 November 2019 1722

Two‐pore channels regulate Tat endolysosome escape and Tat‐mediated HIV‐1 LTR transactivation

Authors: Khan, Nabab, Halcrow, Peter W., Lakpa, Koffi L., Afghah, Zahra, Miller, Nicole M., Dowdy, Steven F., Geiger, Jonathan D., Chen, Xuesong

Source: FASEB journal. 34(3):4147-4162

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Readily Releasable Stores of Calcium in Neuronal Endolysosomes: Physiological and Pathophysiological Relevance

Authors: Lakpa, Koffi L., Halcrow, Peter W., Chen, Xuesong, Geiger, Jonathan D.

Source: Advances in experimental medicine and biology. 1131(2):681-698

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622248747&indx=1&recIds=ETOCRN622248747

Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model

Authors: Vacano, Guido N., Gibson, David S., Turjoman, Abdullah Arif, Gawryluk, Jeremy W., Geiger, Jonathan D., Duncan, Mark, Patterson, David

Source: In Neurobiology of Aging March 2018 63:96-109

HIV‐1 Tat endocytosis and retention in endolysosomes affects HIV‐1 Tat‐induced LTR transactivation in astrocytes

Authors: Khan, Nabab, Halcrow, Peter W., Afghah, Zahra, Baral, Aparajita, Geiger, Jonathan D., Chen, Xuesong

Source: FASEB journal. 36(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142199647.0x000001&indx=1&recIds=ETOCvdc_100142199647.0x000001

Doping-Control Urinalysis of a Ginseng Extract, Cold-FX®, in Athletes.

Alternate Title: With appendix

Authors: Goel, Danny P., Geiger, Jonathan D., Shan, Jacqueline J.

Source: International Journal of Sport Nutrition & Exercise Metabolism; August 2004, Vol. 14 Issue 4, p473-480, 8p

Involvement of Endolysosomes and Aurora Kinase A in the Regulation of Amyloid β Protein Levels in Neurons.

Authors: Afghah, Zahra, Khan, Nabab, Datta, Gaurav, Halcrow, Peter W., Geiger, Jonathan D., Chen, Xuesong

Source: International Journal of Molecular Sciences; Jun2024, Vol. 25 Issue 11, p6200, 11p

Subject Terms: AURORA kinases, CATHEPSIN D, AMYLOID, NEURONS, AMYLOID plaque, TUBULINS, AMYLOID beta-protein precursor

HERV-K (HML-2) Envelope Protein Induces Mitochondrial Depolarization and Neurotoxicity via Endolysosome Iron Dyshomostasis.

Authors: Halcrow, Peter W., Quansah, Darius N. K., Kumar, Nirmal, Steiner, Joseph P., Nath, Avindra, Geiger, Jonathan D.

Source: Journal of Neuroscience; 4/3/2024, Vol. 44 Issue 14, p1-16, 16p

Subject Terms: MOTOR neuron diseases, MITOCHONDRIAL proteins, HUMAN endogenous retroviruses, AMYOTROPHIC lateral sclerosis, CELL death, NEUROTOXICOLOGY, CHELATING agents, REACTIVE oxygen species, CELL culture

Apolipoprotein E isoform dependently affects Tat-mediated HIV-1 LTR transactivation

Authors: Khan, Nabab, Datta, Gaurav, Geiger, Jonathan, Chen, Xuesong

Source: Journal of neuroinflammation. 15(1):1-11

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Weak base drug-induced endolysosome iron dyshomeostasis controls the generation of reactive oxygen species, mitochondrial depolarization, and cytotoxicity.

Authors: Halcrow, Peter W., Quansah, Darius N. K., Kumar, Nirmal, Solloway, Rebecca L., Teigen, Kayla M., Lee, Kasumi A., Liang, Braelyn, Geiger, Jonathan D.

Source: NeuroImmune Pharmacology & Therapeutics; Mar2024, Vol. 3 Issue 1, p33-46, 14p

Subject Terms: HOMEOSTASIS, REACTIVE oxygen species, MITOCHONDRIAL DNA, LYSOSOMES, PHARMACOLOGY

Release of calcium from endolysosomes increases calcium influx through N-type calcium channels: Evidence for acidic store-operated calcium entry in neurons

Authors: Hui, Liang, Geiger, Nicholas H., Bloor-Young, Duncan, Churchill, Grant C., Geiger, Jonathan D., Chen, Xuesong

Source: In Cell Calcium December 2015 58(6):617-627

Ketogenic diet sensitizes glucose control of hippocampal excitability

Authors: Kawamura, Masahito, Jr. ^*, Ruskin, David N. ^†, Geiger, Jonathan D. ^§, Boison, Detlev ^**, Masino, Susan A. ^†

Source: In Journal of Lipid Research November 2014 55(11):2254-2260

Endolysosome involvement in HIV-1 transactivator protein-induced neuronal amyloid beta production

Authors: Chen, Xuesong, Hui, Liang, Geiger, Nicholas H., Haughey, Norman J., Geiger, Jonathan D.

Source: In Neurobiology of Aging October 2013 34(10):2370-2378