Decompensated Liver Cirrhosis Research Network (UK-CLIF): Building consensus for hepatology trials in the UK [version 1; peer review: 2 approved]

Authors: Yvanne Enever, Oliver Tavabie, Juan Acevedo, Richard Allen, Brian Hogan, Abhishek Chauhan, Rajeshwar Mookerjee, Vishal Patel, Richard Aspinall, Gavin Wright, Andrew Cook, Stuart McPherson, Gautam Mehta, Rajiv Jalan, Milton Silverman, Helen Crisp

Source: NIHR Open Research, Vol 4 (2024)

Subject Terms: Liver cirrhosis, clinical trials, alcohol, eng, Medicine

File Description: electronic resource

Relation: https://openresearch.nihr.ac.uk/articles/4-69/v1; https://doaj.org/toc/2633-4402

Access URL: https://doaj.org/article/1c3faf7cd73741bc972c240581f2c21a

Systematic review and meta-analysis of biomarkers predicting decompensation in patients with compensated cirrhosis

Authors: Gautam Mehta, Kohilan Gananandan, Rabiah Singh

Source: BMJ Open Gastroenterology, Vol 11, Iss 1 (2024)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://bmjopengastro.bmj.com/content/11/1/e001430.full; https://doaj.org/toc/2054-4774

Access URL: https://doaj.org/article/7cd71212f755451d879cc1e0eb933dbb

Binge-pattern alcohol consumption and genetic risk as determinants of alcohol-related liver disease

Authors: Chengyi Ding, Linda Ng Fat, Annie Britton, Pek Kei Im, Kuang Lin, Anya Topiwala, Liming Li, Zhengming Chen, Iona Y. Millwood, Steven Bell, Gautam Mehta

Source: Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/dcafe0e689764fa7be18ce55e256937a

AlcoChange: A digital therapeutic for patients with alcohol-related liver disease

Authors: Gautam Mehta, Su Lin, Aida Nadar, Bharadwaj PV, Ravi Kumar, Anu Balaji, Stewart Macdonald, Mohammed F. Sheikh, MohammadMahdi Saeidinejad, Shiv-Raj Sharma, Ji J. King, Rajeshwar P. Mookerjee, Lorraine McDonagh, Sarah A. Afuwape, Kevin Moore, Rajiv Jalan

Source: JHEP Reports, Vol 6, Iss 4, Pp 100993- (2024)

Subject Terms: Alcohol-related liver disease, alcohol, digital health, digital therapeutic, smartphone, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923003245; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/8ffcdaf7fc364e668a44cd461e54e77e

Vaccination in liver diseases and liver transplantation: Recommendations, implications and opportunities in the post-COVID eraKey points

Authors: Maria Pilar Ballester, Rajiv Jalan, Gautam Mehta

Source: JHEP Reports, Vol 5, Iss 8, Pp 100776- (2023)

Subject Terms: Vaccination, COVID-19, hepatitis, cirrhosis, liver transplant, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923001076; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/ddf698f50678439e8fb6e6ad5d2c3024

Editorial: Advances in platforms for disease modelling

Authors: Leonardo Romorini, Sukriti Baweja, Rosa Maria Martin Mateos, Gautam Mehta, Nidhi Jalan-Sakrikar

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: big data, sequencing, artificial intelligence, CRISPR, biomarker, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.1190492/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/6c5d5d6a33bc4c0b9acc646a11745153

The role of RIPK1 mediated cell death in acute on chronic liver failure

Authors: Takayuki Kondo, Stewart Macdonald, Cornelius Engelmann, Abeba Habtesion, Jane Macnaughtan, Gautam Mehta, Rajeshwar P. Mookerjee, Nathan Davies, Marco Pavesi, Richard Moreau, Paolo Angeli, Vicente Arroyo, Fausto Andreola, Rajiv Jalan

Source: Cell Death and Disease, Vol 13, Iss 1, Pp 1-12 (2021)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/2491ace6c56640c794f84a8922eb4c18

A permeability assay for mouse intestinal organoids

Authors: Stijn Aaron den Daas, Ugo Soffientini, Shilpa Chokshi, Gautam Mehta

Source: STAR Protocols, Vol 3, Iss 2, Pp 101365- (2022)

Subject Terms: Health Sciences, Model Organisms, Organoids, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166722002453; https://doaj.org/toc/2666-1667

Access URL: https://doaj.org/article/4369f827ef8449949132af4ed9032454

The Lipopolysaccharide-Sensing Caspase(s)-4/11 Are Activated in Cirrhosis and Are Causally Associated With Progression to Multi-Organ Injury

Authors: Ugo Soffientini, Nigel Beaton, Sukriti Baweja, Emmanuel Weiss, Chhagan Bihari, Abeba Habtesion, Vishal Patel, Valerie Paradis, Archana Sharma, Tu Vinh Luong, Andrew Hall, Aida Nadar, Shiv Sarin, Shilpa Chokshi, Roger Williams, Benedicte Py, Richard Moreau, Rajiv Jalan, Gautam Mehta

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: cirrhosis, lipopolysaccharide, caspase, liver failure, endotoxin, dysbiosis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.668459/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/57a35ab6ce234be49771b0d60ea019f8

Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF

Authors: Emmanuel Weiss, Pierre de la Grange, Mylène Defaye, Juan José Lozano, Ferrán Aguilar, Pushpa Hegde, Ariane Jolly, Lucile Moga, Sukriti Sukriti, Banwari Agarwal, Haqeeqat Gurm, Marion Tanguy, Johanne Poisson, Joan Clària, Paer-Selim Abback, Axel Périanin, Gautam Mehta, Rajiv Jalan, Claire Francoz, Pierre-Emmanuel Rautou, Sophie Lotersztajn, Vicente Arroyo, François Durand, Richard Moreau

Source: Frontiers in Immunology, Vol 11 (2021)

Subject Terms: myeloid cells, innate lymphoid cells, adaptive immune cells, sepsis, organ failure, immunotherapies, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.619039/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/08bb7077b5d446efbff237f3b2fd3c80

Disulfiram use is associated with lower risk of COVID-19: A retrospective cohort study

Authors: Nathanael Fillmore, Steven Bell, Ciyue Shen, Vinh Nguyen, Jennifer La, Maureen Dubreuil, Judith Strymish, Mary Brophy, Gautam Mehta, Hao Wu, Judy Lieberman, Nhan Do, Chris Sander

Source: PLoS ONE, Vol 16, Iss 10 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553043/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/694be54517884332bd8562bdd372b525

Correction: The role of RIPK1 mediated cell death in acute on chronic liver failure

Authors: Takayuki Kondo, Stewart Macdonald, Cornelius Engelmann, Abeba Habtesion, Jane Macnaughtan, Gautam Mehta, Rajeshwar P. Mookerjee, Nathan Davies, Marco Pavesi, Richard Moreau, Paolo Angeli, Vicente Arroyo, Fausto Andreola, Rajiv Jalan

Source: Cell Death and Disease, Vol 13, Iss 4, Pp 1-1 (2022)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/286e62507fa646dc82ec6581043b920d

Regulation of Monocyte-Macrophage Responses in Cirrhosis—Role of Innate Immune Programming and Checkpoint Receptors

Authors: Antonio Riva, Gautam Mehta

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: cirrhosis, ACLF, ARLD, ALD, alcoholic hepatitis, innate immune cell, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00167/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/73cf8a5aee2e465e9a64288f012bfe08

Suspected Intestinal Tuberculosis Might Be Crohn's Disease

Authors: Semiu Eniola Folaranmi, Gautam Mehta, Debasis Datta, Greg Holdstock

Source: Case Reports in Medicine, Vol 2010 (2010)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1687-9627; https://doaj.org/toc/1687-9635

Access URL: https://doaj.org/article/5fc55dc3036847e3add0a6352abb5603

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The transcription factor BACH2 promotes tumor immunosuppression.

Authors: Roychoudhuri, Rahul, Eil, Robert L., Clever, David, Klebanoff, Christopher A., Sukumar, Madhusudhanan, Grant, Francis M., Zhiya Yu, Gautam Mehta, Hui Liu, Ping Jin, Yun Ji, Palmer, Douglas C., Pan, Jenny H., Chichura, Anna, Crompton, Joseph G., Patel, Shashank J., Stroncek, David, Ena Wang, Marincola, Francesco M., Okkenhaug, Klaus

Source: Journal of Clinical Investigation. Feb2016, Vol. 126 Issue 2, p599-604. 6p. 3 Graphs.

Subjects: TUMOR prevention, IMMUNOSUPPRESSION, TRANSCRIPTION factors, KILLER cells, LABORATORY mice, ANIMAL experimentation, ANIMALS, IMMUNITY, INTERFERONS, MICE, PROTEINS, RESEARCH funding, T cells, TUMORS