Microbial impact to environmental toxicants Ni(II) and Co(II): Joint toxicity and cellular response in Paramecium

Authors: Garza Amaya, Diana Laura, Thiel, Alicia, Möller, Melanie, Gasparoni, Gilles, Pirritano, Marcello, Drews, Franziska, Bornhorst, Julia, Simon, Martin

Source: In Chemosphere December 2023 345

Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood

Authors: Ferrari, Raffaele, Hernandez, Dena G., Nalls, Michael A., Rohrer, Jonathan D., Ramasamy, Adaikalavan, Kwok, John B.J., Dobson-Stone, Carol, Brooks, William S., Schofield, Peter R., Halliday, Glenda M., Hodges, John R., Piguet, Olivier, Bartley, Lauren, Thompson, Elizabeth, Haan, Eric, Hernández, Isabel, Ruiz, Agustín, Boada, Mercè, Borroni, Barbara, Padovani, Alessandro, Cruchaga, Carlos, Cairns, Nigel J., Benussi, Luisa, Binetti, Giuliano, Ghidoni, Roberta, Forloni, Gianluigi, Galimberti, Daniela, Fenoglio, Chiara, Serpente, Maria, Scarpini, Elio, Clarimón, Jordi, Lleó, Alberto, Blesa, Rafael, Waldö, Maria Landqvist, Nilsson, Karin, Nilsson, Christer, Mackenzie, Ian R.A., Hsiung, Ging-Yuek R., Mann, David M.A., Grafman, Jordan, Morris, Christopher M., Attems, Johannes, Griffiths, Timothy D., McKeith, Ian G., Thomas, Alan J., Pietrini, P., Huey, Edward D., Wassermann, Eric M., Baborie, Atik, Jaros, Evelyn, Tierney, Michael C., Pastor, Pau, Razquin, Cristina, Ortega-Cubero, Sara, Alonso, Elena, Perneczky, Robert, Diehl-Schmid, Janine, Alexopoulos, Panagiotis, Kurz, Alexander, Rainero, Innocenzo, Rubino, Elisa, Pinessi, Lorenzo, Rogaeva, Ekaterina, St. George-Hyslop, Peter, Rossi, Giacomina, Tagliavini, Fabrizio, Giaccone, Giorgio, Rowe, James B., Schlachetzki, Johannes C.M., Uphill, James, Collinge, John, Mead, Simon, Danek, Adrian, Van Deerlin, Vivianna M., Grossman, Murray, Trojanowski, John Q., van der Zee, Julie, Deschamps, William, Van Langenhove, Tim, Cruts, Marc, Van Broeckhoven, Christine, Cappa, Stefano F., Le Ber, Isabelle, Hannequin, Didier, Golfier, Véronique, Vercelletto, Martine, Brice, Alexis, Nacmias, Benedetta, Sorbi, Sandro, Bagnoli, Silvia, Piaceri, Irene, Nielsen, Jørgen E., Hjermind, Lena E., Riemenschneider, Matthias, Mayhaus, Manuel, Ibach, Bernd, Gasparoni, Gilles, Pichler, Sabrina, Gu, Wei, Rossor, Martin N., Fox, Nick C., Warren, Jason D., Spillantini, Maria Grazia, Morris, Huw R., Rizzu, Patrizia, Heutink, Peter, Snowden, Julie S., Rollinson, Sara, Richardson, Anna, Gerhard, Alexander, Bruni, Amalia C., Maletta, Raffaele, Frangipane, Francesca, Cupidi, Chiara, Bernardi, Livia, Anfossi, Maria, Gallo, Maura, Conidi, Maria Elena, Smirne, Nicoletta, Rademakers, Rosa, Baker, Matt, Dickson, Dennis W., Graff-Radford, Neill R., Petersen, Ronald C., Knopman, David, Josephs, Keith A., Boeve, Bradley F., Parisi, Joseph E., Seeley, William W., Miller, Bruce L., Karydas, Anna M., Rosen, Howard, van Swieten, John C., Dopper, Elise G.P., Seelaar, Harro, Pijnenburg, Yolande A.L., Scheltens, Philip, Logroscino, Giancarlo, Capozzo, Rosa, Novelli, Valeria, Puca, Annibale A., Franceschi, Massimo, Postiglione, Alfredo, Milan, Graziella, Sorrentino, Paolo, Kristiansen, Mark, Chiang, Huei-Hsin, Graff, Caroline, Pasquier, Florence, Rollin, Adeline, Deramecourt, Vincent, Lebert, Florence, Kapogiannis, Dimitrios, Ferrucci, Luigi, Pickering-Brown, Stuart, Singleton, Andrew B., Hardy, John, Momeni, Parastoo, Ge, Yi-Jun, Ou, Ya-Nan, Deng, Yue-Ting, Wu, Bang-Sheng, Yang, Liu, Zhang, Ya-Ru, Chen, Shi-Dong, Huang, Yu-Yuan, Dong, Qiang, Tan, Lan, Yu, Jin-Tai

Source: In Biological Psychiatry 1 May 2023 93(9):770-779

Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells

Authors: Nell, Patrick, Kattler, Kathrin, Feuerborn, David, Hellwig, Birte, Rieck, Adrian, Salhab, Abdulrahman, Lepikhov, Konstantin, Gasparoni, Gilles, Thomitzek, Antonia, Belgasmi, Katharina, Blüthgen, Nils, Morkel, Markus, Küppers-Munther, Barbara, Godoy, Patricio, Hay, David C., Cadenas, Cristina, Marchan, Rosemarie, Vartak, Nachiket, Edlund, Karolina, Rahnenführer, Jörg, Walter, Jörn, Hengstler, Jan G.

Source: In Journal of Hepatology November 2022 77(5):1386-1398

Resident memory CD4+ T lymphocytes mobilize from bone marrow to contribute to a systemic secondary immune reaction

Authors: Cendón, Carla, Du, Weijie, Durek, Pawel, Liu, Yuk‐Chien, Alexander, Tobias, Serene, Lindsay, Yang, Xinyi, Gasparoni, Gilles, Salhab, Abdulrahman, Nordström, Karl, Lai, Tina, Schulz, Axel R., Rao, Anna, Heinz, Gitta A., Stefanski, Ana L., Claußnitzer, Anne, Siewert, Katherina, Dörner, Thomas, Chang, Hyun‐Dong, Volk, Hans‐Dieter, Romagnani, Chiara, Qin, Zhihai, Hardt, Sebastian, Perka, Carsten, Reinke, Simon, Walter, Jörn, Mashreghi, Mir‐Farzin, Thurley, Kevin, Radbruch, Andreas, Dong, Jun

Source: European journal of immunology. 52(5):737-752

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100150378440.0x000001&indx=1&recIds=ETOCvdc_100150378440.0x000001

Dysregulation of cholesterol homeostasis in human lung cancer tissue and tumour-associated macrophages

Authors: Hoppstädter, Jessica, Dembek, Anna, Höring, Marcus, Schymik, Hanna S., Dahlem, Charlotte, Sultan, Afnan, Wirth, Natalie, Al-Fityan, Salma, Diesel, Britta, Gasparoni, Gilles, Walter, Jörn, Helms, Volkhard, Huwer, Hanno, Simon, Martin, Liebisch, Gerhard, Schulz, Marcel H., Kiemer, Alexandra K.

Source: In eBioMedicine October 2021 72

Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria

Authors: Gianmoena, Kathrin, Gasparoni, Nina, Jashari, Adelina, Gabrys, Philipp, Grgas, Katharina, Ghallab, Ahmed, Nordström, Karl, Gasparoni, Gilles, Reinders, Jörg, Edlund, Karolina, Godoy, Patricio, Schriewer, Alexander, Hayen, Heiko, Hudert, Christian A., Damm, Georg, Seehofer, Daniel, Weiss, Thomas S., Boor, Peter, Anders, Hans-Joachim, Motrapu, Manga, Jansen, Peter, Schiergens, Tobias S., Falk-Paulsen, Maren, Rosenstiel, Philip, Lisowski, Clivia, Salido, Eduardo, Marchan, Rosemarie, Walter, Jörn, Hengstler, Jan G., Cadenas, Cristina

Source: In Cell Reports 24 August 2021 36(8)

Gene Expression Imputation Across Multiple Tissue Types Provides Insight Into the Genetic Architecture of Frontotemporal Dementia and Its Clinical Subtypes

Authors: Ferrari, Raffaele, Hernandez, Dena G., Nalls, Michael A., Rohrer, Jonathan D., Ramasamy, Adaikalavan, Kwok, John B.J., Dobson-Stone, Carol, Brooks, William S., Schofield, Peter R., Halliday, Glenda M., Hodges, John R., Piguet, Olivier, Bartley, Lauren, Thompson, Elizabeth, Hernández, Isabel, Ruiz, Agustín, Boada, Mercè, Borroni, Barbara, Padovani, Alessandro, Cruchaga, Carlos, Cairns, Nigel J., Benussi, Luisa, Binetti, Giuliano, Ghidoni, Roberta, Forloni, Gianluigi, Galimberti, Daniela, Fenoglio, Chiara, Serpente, Maria, Scarpini, Elio, Clarimón, Jordi, Lleó, Alberto, Blesa, Rafael, Waldö, Maria Landqvist, Nilsson, Karin, Nilsson, Christer, Mackenzie, Ian R.A., Hsiung, Ging-Yuek R., Mann, David M.A., Grafman, Jordan, Morris, Christopher M., Attems, Johannes, Griffiths, Timothy D., McKeith, Ian G., Thomas, Alan J., Pietrini, Pietro, Huey, Edward D., Wassermann, Eric M., Baborie, Atik, Jaros, Evelyn, Tierney, Michael C., Pastor, Pau, Razquin, Cristina, Ortega-Cubero, Sara, Alonso, Elena, Perneczky, Robert, Diehl-Schmid, Janine, Alexopoulos, Panagiotis, Kurz, Alexander, Rainero, Innocenzo, Rubino, Elisa, Pinessi, Lorenzo, Rogaeva, Ekaterina, St. George-Hyslop, Peter, Rossi, Giacomina, Tagliavini, Fabrizio, Giaccone, Giorgio, Rowe, James B., Schlachetzki, Johannes C.M., Uphill, James, Collinge, John, Mead, Simon, Danek, Adrian, Van Deerlin, Vivianna M., Grossman, Murray, Trojanowski, John Q., van der Zee, Julie, Van Broeckhoven, Christine, Cappa, Stefano F., Le Ber, Isabelle, Hannequin, Didier, Golfier, Véronique, Vercelletto, Martine, Brice, Alexis, Nacmias, Benedetta, Sorbi, Sandro, Bagnoli, Silvia, Piaceri, Irene, Nielsen, Jørgen E., Hjermind, Lena E., Riemenschneider, Matthias, Mayhaus, Manuel, Ibach, Bernd, Gasparoni, Gilles, Pichler, Sabrina, Gu, Wei, Rossor, Martin N., Fox, Nick C., Warren, Jason D., Spillantini, Maria Grazia, Morris, Huw R., Rizzu, Patrizia, Heutink, Peter, Snowden, Julie S., Rollinson, Sara, Richardson, Anna, Gerhard, Alexander, Bruni, Amalia C., Maletta, Raffaele, Frangipane, Francesca, Cupidi, Chiara, Bernardi, Livia, Anfossi, Maria, Gallo, Maura, Conidi, Maria Elena, Smirne, Nicoletta, Rademakers, Rosa, Baker, Matt, Dickson, Dennis W., Graff-Radford, Neill R., Petersen, Ronald C., Knopman, David, Josephs, Keith A., Boeve, Bradley F., Parisi, Joseph E., Seeley, William W., Miller, Bruce L., Karydas, Anna M., Rosen, Howard, van Swieten, John C., Dopper, Elise G.P., Seelaar, Harro, Pijnenburg, Yolande A.L., Scheltens, Philip, Logroscino, Giancarlo, Capozzo, Rosa, Novelli, Valeria, Puca, Annibale A., Franceschi, Massimo, Postiglione, Alfredo, Milan, Graziella, Sorrentino, Paolo, Kristiansen, Mark, Chiang, Huei-Hsin, Graff, Caroline, Pasquier, Florence, Rollin, Adeline, Deramecourt, Vincent, Lebert, Florence, Kapogiannis, Dimitrios, Ferrucci, Luigi, Pickering-Brown, Stuart, Singleton, Andrew B., Hardy, John, Momeni, Parastoo, Reus, Lianne M., Pasaniuc, Bogdan, Posthuma, Danielle, Boltz, Toni, Ophoff, Roel A.

Source: In Biological Psychiatry 15 April 2021 89(8):825-835

Two Piwis with Ago-like functions silence somatic genes at the chromatin level

Authors: Drews, Franziska, Karunanithi, Sivarajan, Götz, Ulrike, Marker, Simone, deWijn, Raphael, Pirritano, Marcello, Rodrigues-Viana, Angela M., Jung, Martin, Gasparoni, Gilles, Schulz, Marcel H., Simon, Martin

Source: RNA biology. 18(S2):757-769

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139436704.0x000001&indx=1&recIds=ETOCvdc_100139436704.0x000001

Epigenetic control of region‐specific transcriptional programs in mouse cerebellar and cortical astrocytes

Authors: Welle, Anna, Kasakow, Carmen V., Jungmann, Annemarie M., Gobbo, Davide, Stopper, Laura, Nordström, Karl, Salhab, Abdulrahman, Gasparoni, Gilles, Scheller, Anja, Kirchhoff, Frank, Walter, Jörn

Source: Glia. 69(9):2160-2177

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123866230.0x000001&indx=1&recIds=ETOCvdc_100123866230.0x000001

Antisense Oligonucleotide- and CRISPR-Cas9-Mediated Rescue of mRNA Splicing for a Deep Intronic CLRN1 Mutation

Authors: Panagiotopoulos, Anna-Lena, Karguth, Nina, Pavlou, Marina, Böhm, Sybille, Gasparoni, Gilles, Walter, Jörn, Graf, Alexander, Blum, Helmut, Biel, Martin, Riedmayr, Lisa Maria, Becirovic, Elvir

Source: In Molecular Therapy - Nucleic Acids 4 September 2020 21:1050-1061

A Monoclonal Human Alveolar Epithelial Cell Line ('Arlo') with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections

Authors: Carius, Patrick, Jungmann, Annemarie, Bechtel, Marco, Grißmer, Alexander, Boese, Annette, Gasparoni, Gilles, Salhab, Abdulrahman, Seipelt, Ralf, Urbschat, Klaus, Richter, Clémentine, Meier, Carola, Bojkova, Denisa, Cinatl, Jindrich, Walter, Jörn, Schneider‐Daum, Nicole, Lehr, Claus‐Michael

Source: Advanced science. 10(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181443672.0x000001&indx=1&recIds=ETOCvdc_100181443672.0x000001

Neuronal deficiency of p38α‐MAPK ameliorates symptoms and pathology of APP or Tau‐transgenic Alzheimer's mouse models

Authors: Schnöder, Laura, Gasparoni, Gilles, Nordström, Karl, Schottek, Andrea, Tomic, Inge, Christmann, Anne, Schäfer, Karl H., Menger, Michael D., Walter, Jörn, Fassbender, Klaus, Liu, Yang

Source: FASEB journal. 34(7):9628-9649

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107522190.0x000001&indx=1&recIds=ETOCvdc_100107522190.0x000001

Shedding light on starvation in darkness in the plastid-bearing sea slug Elysia viridis (Montagu, 1804).

Authors: Frankenbach, Silja¹, Melo Clavijo, Jenny², Brück, Michael², Bleidißel, Sabrina², Simon, Martin³, Gasparoni, Gilles⁴, Lo Porto, Christina⁴, Laetz, Elise M. J.⁵, Greve, Carola⁶, Donath, Alexander⁷, Pütz, Laura⁸, Sickinger, Corinna², Serôdio, João¹, Christa, Gregor², christa@uni-wuppertal.de

Source: Marine Biology; Jul2023, Vol. 170 Issue 7, p1-15, 15p

Lack of H3K27 trimethylation is associated with 1p/19q codeletion in diffuse gliomas

Authors: Filipski, Katharina, Braun, Yannick, Zinke, Jenny, Roller, Bastian, Baumgarten, Peter, Wagner, Marlies, Senft, Christian, Zeiner, Pia S., Ronellenfitsch, Michael W., Steinbach, Joachim P., Plate, Karl H., Gasparoni, Gilles, Mittelbronn, Michel, Capper, David, Harter, Patrick N.

Source: Acta neuropathologica. 138(2):331-334

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141525832.0x000001&indx=1&recIds=ETOCvdc_100141525832.0x000001

DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

Authors: Souren, Nicole, Gerdes, Lisa, Lutsik, Pavlo, Gasparoni, Gilles, Beltrán, Eduardo, Salhab, Abdulrahman, Kümpfel, Tania, Weichenhan, Dieter, Plass, Christoph, Hohlfeld, Reinhard, Walter, Jörn

Source: Nature communications. 10(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138177708.0x000001&indx=1&recIds=ETOCvdc_100138177708.0x000001

Mo1517: LONGITUDINAL MULTI-OMICS ANALYSIS IDENTIFIES EARLY BLOODBASED PREDICTORS OF ANTI-TNF THERAPY RESPONSE IN INFLAMMATORY BOWEL DISEASE

Authors: Mishra, Neha, Aden, Konrad, Blase, Johanna I., Bordoni, Dora, Conrad, Claudio C., Avalos, Diana, Jaeckel, Charlot, Baran, Nathan, Scherer, Michael, Sørensen, Signe Bek, Overgaard, Silja H., Nikolaus, Susanna, Rey, Guillaume, Gasparoni, Gilles, Lyons, Paul, Schultze, Joachim, Walter, Jörn, Andersen, Vibeke, Dermitzakis, Emmanouil T, Schreiber, Stefan, Rosenstiel, Philip

Source: Gastroenterology. 162(7):S-800-S-800

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167644097.0x000001&indx=1&recIds=ETOCvdc_100167644097.0x000001

Immunomodulation by glucocorticoid-induced leucine zipper in macrophages: enhanced phagocytosis, protection from pyroptosis, and altered mitochondrial function.

Authors: Legroux, Thierry M., Schymik, Hanna S., Gasparoni, Gilles, Mohammadi, Saeed, Walter, Jörn, Libert, Claude, Diesel, Britta, Hoppstädter, Jessica, Kiemer, Alexandra K.

Source: Frontiers in Immunology; 2024, p1-16, 16p

Subject Terms: LEUCINE zippers, PHAGOCYTOSIS, MACROPHAGES, PYROPTOSIS, IMMUNOREGULATION

Next Generation Sequencing Analysis of Total Small Noncoding RNAs from Low Input RNA from Dried Blood Sampling

Authors: Pirritano, Marcello, Fehlmann, Tobias, Laufer, Thomas, Ludwig, Nicole, Gasparoni, Gilles, Li, Yongping, Meese, Eckart, Keller, Andreas, Simon, Martin

Source: Analytical chemistry. 90(20):11791-11796

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN617888809&indx=1&recIds=ETOCRN617888809

Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters

Authors: Behjati Ardakani, Fatemeh, Kattler, Kathrin, Nordström, Karl, Gasparoni, Nina, Gasparoni, Gilles, Fuchs, Sarah, Sinha, Anupam, Barann, Matthias, Ebert, Peter, Fischer, Jonas, Hutter, Barbara, Zipprich, Gideon, Imbusch, Charles, Felder, Bärbel, Eils, Jürgen, Brors, Benedikt, Lengauer, Thomas, Manke, Thomas, Rosenstiel, Philip, Walter, Jörn, Schulz, Marcel

Source: Epigenetics & chromatin. 11(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185402184.0x000001&indx=1&recIds=ETOCvdc_100185402184.0x000001

A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

Authors: Salhab, Abdulrahman, Nordström, Karl, Gasparoni, Gilles, Kattler, Kathrin, Ebert, Peter, Ramirez, Fidel, Arrigoni, Laura, Müller, Fabian, Polansky, Julia, Cadenas, Cristina, G.Hengstler, Jan, Lengauer, Thomas, Manke, Thomas, Walter, Jörn

Source: Genome biology. 19(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184304161.0x000001&indx=1&recIds=ETOCvdc_100184304161.0x000001