Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis

Authors: Tanaka, Kosuke, Yu, Helena A., Yang, Shaoyuan, Han, Song, Selcuklu, S. Duygu, Kim, Kwanghee, Ramani, Shriram, Ganesan, Yogesh Tengarai, Moyer, Allison, Sinha, Sonali, Xie, Yuchen, Ishizawa, Kota, Osmanbeyoglu, Hatice U., Lyu, Yang, Roper, Nitin, Guha, Udayan, Rudin, Charles M., Kris, Mark G., Hsieh, James J., Cheng, Emily H.

Source: In Cancer Cell 13 September 2021 39(9):1245-1261

ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival

Authors: Wang, Gary X., Tu, Ho-Chou, Dong, Yiyu, Skanderup, Anders Jacobsen, Wang, Yufeng, Takeda, Shugaku, Ganesan, Yogesh Tengarai, Han, Song, Liu, Han, Hsieh, James J., Cheng, Emily H.

Source: In Cell Reports 5 December 2017 21(10):2926-2939

An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway

Authors: Garner, Thomas P., Reyna, Denis E., Priyadarshi, Amit, Chen, Hui-Chen, Li, Sheng, Wu, Yang, Ganesan, Yogesh Tengarai, Malashkevich, Vladimir N., Cheng, Emily H., Gavathiotis, Evripidis

Source: In Molecular Cell 4 August 2016 63(3):485-497

A sandwich ELISA for the conformation-specific quantification of the activated form of human Bax

Authors: Teijido, Oscar, Ganesan, Yogesh Tengarai, Llanos, Raul, Peton, Ashley, Urtecho, Jean-Baptiste, Soprani, Adauri, Villamayor, Aimee, Antonsson, Bruno, Manon, Stéphen, Dejean, Laurent

Source: In Analytical Biochemistry 15 March 2016 497:90-94

Bcl-xL stimulates Bax relocation to mitochondria and primes cells to ABT-737

Authors: Renault, Thibaud T., Teijido, Oscar, Missire, Florent, Ganesan, Yogesh Tengarai, Velours, Gisèle, Arokium, Hubert, Beaumatin, Florian, Llanos, Raul, Athané, Axel, Camougrand, Nadine, Priault, Muriel, Antonsson, Bruno, Dejean, Laurent M., Manon, Stéphen

Source: In International Journal of Biochemistry and Cell Biology July 2015 64:136-146

An interconnected hierarchical model of cell death regulation by the BCL-2 family.

Authors: Hsieh, James J., Cheng, Emily H., Chen, Hui-Chen¹, Kanai, Masayuki¹, Inoue-Yamauchi, Akane¹, Tu, Ho-Chou¹, Huang, Yafen¹, Takeda, Shugaku¹, Chan, Po M.¹, Ganesan, Yogesh Tengarai¹, Liao, Chung-Ping¹, Ren, Decheng², Kim, Hyungjin³, Reyna, Denis E.⁴, Gavathiotis, Evripidis⁴

Source: Nature Cell Biology; Oct2015, Vol. 17 Issue 10, p1270-1281, 12p, 2 Diagrams, 1 Chart, 12 Graphs

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Interactions Between Bcl-2, Bcl-xl, and Bax at the Mitochondria: Keep Your Friends Close but Your Enemies Closer

Authors: Dejean, Laurent, Hermida, Oscar Teijido, Ganesan, Yogesh Tengarai, Renault, Thibaud, Antonsson, Bruno, Manon, Stephen

Source: In Biophysical Journal 2011 100(3) Supplement 1:40a-40a

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