Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development.

Authors: Samper, Natalie, Hardardottir, Lilja, Depierreux, Delphine M., Song, Soomin C., Nakazawa, Ayano, Gando, Ivan, Nakamura, Tomoe Y., Sharkey, Andrew M., Nowosad, Carla R., Feske, Stefan, Colucci, Francesco, Coetzee, William A.

Source: Frontiers in Immunology; 2024, p1-19, 19p

Subject Terms: KILLER cells, POTASSIUM channels, ION channels, BONE cells, NATURAL immunity

A distinct molecular mechanism by which phenytoin rescues a novel long QT 3 variant

Authors: Gando, Ivan, Campana, Chiara, Tan, Reina Bianca, Cecchin, Frank, Sobie, Eric A., Coetzee, William A.

Source: In Journal of Molecular and Cellular Cardiology July 2020 144:1-11

Functional characterization of SCN10A variants in several cases of sudden unexplained death

Authors: Gando, Ivan, Williams, Nori, Fishman, Glenn I., Sampson, Barbara A., Tang, Yingying, Coetzee, William A.

Source: Forensic science international. 301:289-298

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083620955.0x000001&indx=1&recIds=ETOCvdc_100083620955.0x000001

Functional characterization of ABCC9 variants identified in sudden unexpected natural death

Authors: Subbotina, Ekaterina, Yang, Hua-Qian, Gando, Ivan, Williams, Nori, Sampson, Barbara A., Tang, Yingying, Coetzee, William A.

Source: Forensic science international. 298:80-87

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100081883352.0x000001&indx=1&recIds=ETOCvdc_100081883352.0x000001

KATP channels contribute to NK cell cytotoxicity

Authors: Samper, Natalie, Gando, Ivan, Wang, Liwei, Tao, Anthony, Feske, Stefan, Coetzee, William A.

Source: Biophysical journal. 122(S1):523a-524a

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185938445.0x000001&indx=1&recIds=ETOCvdc_100185938445.0x000001

Functional significance of channelopathy gene variants in unexplained death

Authors: Gando, Ivan, Yang, Hua-Qian, Coetzee, William A.

Source: Forensic science, medicine and pathology. 15(3):437-444

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128529417.0x000001&indx=1&recIds=ETOCvdc_100128529417.0x000001

A novel KIR-specific KATP channel opener

Authors: Gando, Ivan, Becerra-Flores, Manuel, Chen, I-Shan, Yang, Hua-Qian, Shyng, Show-Ling, Nakamura, Tomoe Y., Cardozo, Timothy J., Coetzee, William A.

Source: Biophysical journal. 122(S1):257a-257a

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185964282.0x000001&indx=1&recIds=ETOCvdc_100185964282.0x000001

The Transition of the 37-Kda Laminin Receptor (Rpsa) to Higher Molecular Weight Species: Sumoylation or Artifact?

Authors: Digiacomo, Vincent, Gando, Ivan A., Venticinque, Lisa, Hurtado, Alicia, Meruelo, Daniel

Source: Cellular & molecular biology letters. 20(4):571-585

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191528443.0x000001&indx=1&recIds=ETOCvdc_100191528443.0x000001

13 - Functional Characterization of Ion Channel Gene Variants in Sudden Unexplained Natural Death

Authors: Gando, Ivan, Yang, Hua-Qian, Coetzee, William A.

Source: In Zipes and Jalife's Cardiac Electrophysiology Edition: Eighth Edition. 2022:143-154

CL-705G: a novel chemical Kir6.2-specific KATP channel opener.

Authors: Gando, Ivan, Flores, Manuel Becerra, I.-Shan Chen, Hua-Qian Yang, Nakamura, Tomoe Y., Cardozo, Timothy J., Coetzee, William A.

Source: Frontiers in Pharmacology; 2023, p1-17, 17p

Subject Terms: ISCHEMIC preconditioning, MOLECULAR docking, INSULIN regulation, CHEMICAL libraries, BLOOD flow, ION channels, POTASSIUM channels, SODIUM channels, PURINERGIC receptors

The cardioprotective role of sirtuins is mediated in part by regulating KATP channel surface expression.

Authors: Tuncay, Erkan¹, Gando, Ivan², Jian-Yi Huo³, Yepuri, Gautham⁴, Sampler, Natalie², Turan, Belma⁵, Hua-Qian Yang³, Ramasamy, Ravichandran^4,6, Coetzee, William A.^2,6,7 william.coetzee@nyu.edu

Source: American Journal of Physiology: Cell Physiology. May2023, Vol. 324 Issue 5, pC1017-C1027. 11p.

Subject Terms: *SIRTUINS, *NAD (Coenzyme), *TYPE 2 diabetes, *PANCREATIC beta cells, *DEACETYLASES

A homozygous SCN5A mutation associated with atrial standstill and sudden death.

Authors: Tan, Reina Bianca¹, Gando, Ivan¹, Cecchin, Frank¹, Coetzee, William^1,2, Lei Bu³

Source: Pacing & Clinical Electrophysiology. Aug2018, Vol. 41 Issue 8, p1036-1042. 7p.

Subject Terms: *CARDIAC arrest, *SICK sinus syndrome, *ATRIAL arrhythmias, *ELECTRIC capacity, *ELECTROPHYSIOLOGY, *FAMILIES, *MEDICAL screening, *GENETIC mutation, *DATA analysis software, *DESCRIPTIVE statistics, *GENETICS, *DIAGNOSIS

Infant sudden death: Mutations responsible for impaired Nav1.5 channel trafficking and function.

Authors: Gando, Ivan¹, Morganstein, Jace¹, Jana, Kundan¹, McDonald, Thomas V.², Tang, Yingying³, Coetzee, William A.^1,4,5 william.coetzee@med.nyu.edu

Source: Pacing & Clinical Electrophysiology. Jun2017, Vol. 40 Issue 6, p703-712. 10p.

Subject Terms: *SUDDEN infant death syndrome, *BRUGADA syndrome, *CELL culture, *ELECTROPHYSIOLOGY, *FLUORESCENT antibody technique, *GENETIC techniques, *GENETIC mutation, *POLYMERASE chain reaction, *SODIUM, *MEMBRANE transport proteins, *GENETICS

Subcellular trafficking and endocytic recycling of KATP channels.

Authors: Hua-Qian Yang, Echeverry, Fabio A., ElSheikh, Assmaa, Gando, Ivan, Arredondo, Sophia Anez, Samper, Natalie, Cardozo, Timothy, Delmar, Mario, Show-Ling Shyng, Coetzee, William A.

Source: American Journal of Physiology: Cell Physiology; Jun2022, Vol. 322 Issue 6, pC1230-C1247, 18p

Subject Terms: CELL physiology, HEART cells, PANCREATIC beta cells, DRUG therapy, SMOOTH muscle, MYOCARDIUM, POTASSIUM channels, ENDOCYTOSIS

Contributors

Authors: Abrams, Dominic, Abriel, Hugues, Adkisson, Wayne O., Ajijola, Olujimi A., Alvarado, Francisco J., Amin, Ahmad S., André, Clémentine, Anter, Elad, Antzelevitch, Charles, Ariga, Rina, Arora, Rishi, Arya, Arash, Asirvatham, Samuel, Atienza, Felipe, Atluri, Pavan, Balse, Elise, Basso, Cristina, Benditt, David G., Bennett, Richard, Berenfeld, Omer, Berruezo, Antonio, Bers, Donald M., Bhaskaran, Ashwin, Bogun, Frank, Bose, Rupan, Botzer, Lior, Boyle, Patrick M., Bradfield, Jason S., Brini, Marisa, Brugada, Pedro, Caldwell, Jessica L., Calkins, Hugh, Poindexter, Catherine Ellen, Callans, David J., Carafoli, Ernesto, Catterall, William A., Cerrone, Marina, Chandler, Stephanie, Chauvel, Remi, Chen, Lan S., Chen, Peng-Sheng, Cheniti, Ghassen, Cheung, Christopher C., Chiamvimonvat, Nipavan, Chiang, David Y., Chorin, Ehud, Christini, David J., Christoffels, Vincent M., Christoph, Jan, Clancy, Colleen E., Climent, Andreu M., Cochet, Hubert, Coetzee, William A., Crossley, George H., Crotti, Lia, Cuculich, Phillip S., Curtis, Anne B., Dagradi, Federica, Damiano, Ralph J., Jr, Darbar, Dawood, Das, Mithilesh K., Delmar, Mario, Delpón, Eva, Derval, Nicolas, Deshmukh, Abhishek, Dherange, Parinita, Dickfeld, Timm M., Dierckx, Hans, Dinov, Borislav, Divakaran, Sanjay, Dixit, Sanjay, Dubois, Rémi, Duchateau, Josselin, Edwards, Andrew G., Ellenbogen, Kenneth A., Ellinor, Patrick T., Ellis, Christopher R., Enriquez, Andres, Estes III, N.A. Mark, Etheridge, Susan P., Everett, Thomas H., Fedorov, Vadim V., Filgueiras-Rama, David, Fishbein, Michael, Fishman, Glenn I., Fradley, Michael, Gami, Apoor S., Gando, Ivan, Garabelli, Paul James, Garcia, Fermin, George, Alfred L., Jr, Gerstenfeld, Edward P., Goldberger, Jeffrey J., Gourdie, Robert G., Grace, Andrew, Grubb, Blair P., Guerrier, Karine, Guillem, María S., Györke, Sándor, Haines, David E., Halperin, Henry R., Hatem, Stéphane, Haïssaguerre, Michel, Herron, Todd J., Hindricks, Gerhard, Hocini, Mélèze, Hoffman, Jacob, Hund, Thomas J., Hutchinson, Mathew D., Iliceto, Sabino, Ilkhanoff, Leonard, Ingles, Jodie, Ip, James E., Jackman, Warren M., Jalife, Jose, Jaïs, Pierre, Jhun, Bong Sook, Restrepo, Alejandro Jimenez, John, Roy M., Johnson, Jason, Jongbloed, Monique, Jáuregui, Beatriz, Kalman, Jonathan M., Kalyanasundaram, Anuradha, Kamp, Timothy J., Kanagasundram, Arvindh N., Kang, Po Wei, Kanj, Mohamed H., Kapa, Suraj, Kapur, Sunil, Karabin, Beverly, Kernik, Divya C., Klein, George J., Kléber, André G., Knight, Bradley P., Koenig, Sara N., Kohl, Peter, Konecny, Thomas, Koneru, Jayanthi N., Krahn, Andrew D., Krishnappa, Darshan, Krogh-Madsen, Trine, Kumar, Saurabh, Kusayama, Takashi, Kushnir, Alexander, Kwak, Brenda R., Lador, Adi, Lakatta, Edward G., Laksman, Zachary W.M., Latchamsetty, Rakesh, Lau, Dennis H., Lee, Byron K., Lenaeus, Michael J., Lerman, Bruce B., Li, Ning, Lin, Shien-Fong, Link, Mark S., Liu, Bin, Liu, Christopher F., Lockwood, Deborah J., Loeys, Bart, Lubitz, Steven A., Prof-Dr, Stefan Luther, Lyon, Aurore, MacGregor, Robert M., MacRae, Calum A., Maher, Timothy, Maltsev, Victor, Man, Joyce C.K., Marchlinski, Francis E., Markowitz, Steven M., Maron, Barry J., Maron, Martin S., Marra, Martina Perazzolo, Marx, Steven O., Mazzanti, Andrea, McCulloch, Andrew D., Mehta, Nishaki K., Melby, Spencer J., Mellor, Greg, Michaud, Gregory F., Miles, William M., Miller, Jennifer C., Miller, John M., Mitrani, Raul D., Mohler, Peter J., Montgomery, Jay A., Moreno, Jonathan D., Murray, Katherine T., Myerburg, Robert J., Nakagawa, Hiroshi, Naksuk, Niyada, Nalliah, Chrishan Joseph, Napolitano, Carlo, Narayan, Sanjiv M., Nazarian, Saman, Nerbonne, Jeanne M., Nery, Pablo B., Nguyen, Thao P., Nichols, Colin G., Nielsen, Morten S., Nogami, Akihiko, Noujaim, Sami F., Nubret, Karine, O-Uchi, Jin, Olgin, Jeffrey E., Olshansky, Brian, Ozcan, Cevher, Pambrun, Thomas, Panfilov, Alexander V., Pang, Paul D., Park, David S., Parlitz, Ulrich, Patocskai, Bence, Pauziene, Neringa, Pauža, Dainius H., Penela, Diego, Peyronnet, Rémi, Pfenniger, Anna, Phillips, S. Tyler, Picard, François, Ploux, Sylvain, Po, Sunny S., Poelzing, Steven, Polina, Iuliia, Porta-Sánchez, Andreu, Prasad, Abhiram, Priori, Silvia G., Pérez-Hernández, Marta, Qian, Pierre C., Quintanilla, MScEng, Jorge G., Radwański, Przemysław B., Ramirez, F. Daniel, Rappel, Wouter-Jan, Richardson, Travis D., Ripplinger, Crystal M., Robinson, Clifford G., Roden, Dan M., Rodrigo, Miguel, Rodriguez, Blanca, Rosso, Raphael, Rowin, Ethan J., Rudy, Yoram, Rysevaite-Kyguoliene, Kristina, Sacher, Frédéric, Sadek, Mouhannad M., Sanders, Prashanthan, Satin, Jonathan, Sauer, William H., Saxon, Leslie A., Schalij, Martin Jan, Schepers, Dorien, Scherlag, Benjamin J., Schleifer, J. William, Schmidt, Ehud J., Schröder-Schetelig, Johannes, Schuessler, Richard B., Schwartz, Peter J., Semsarian, Christopher, Shaw, Robin M., Shen, Win-Kuang, Sheu, Shey-Shing, Shivkumar, Kalyanam, Sieliwonczyk, Ewa, Silva, Jonathan R., Skanes, Allan C., Smyth, James W., Sobie, Eric A., Soejima, Kyoko, Somers, Virend K., Sorajja, Dan, Sroubek, Jakub, Stavrakis, Stavros, Steinberg, Christian, Stevenson, William G., Supple, Gregory E., Swerdlow, Charles, Tandri, Harikrishna, Tedrow, Usha, Thai, Phung N., Thiene, Gaetano, Tixier, Romain, Tomaselli, Gordon F., Towbin, Jeffrey A., Trayanova, Natalia A., Tristani-Firouzi, Martin, Tseng, Zian H., Tung, Roderick, Ueda, Akiko, Upadhyay, Gaurav A., Valderrábano, Miguel, Valdivia, Héctor H., van den Brink, Jonas, van der Werf, Christian, van Opbergen, Chantal J.M., Vaseghi, Marmar, Vautier, R. Ashton, Vera Pedrosa, Maria Linarejos, Verma, Nishant, Vermij, Sarah H., Virk, Sohaib, Viskin, Sami, Vlachos, Konstantinos, Walsh, Edward P., Wang, Paul J., Welte, Nicolas, Wilde, Arthur A.M., Wilkoff, Bruce L., Wu, Joseph C., Yang, Hua-Qian, Yee, Raymond, Zaman, Junaid A.B., Zeppenfeld, Katja, Zghaib, Tarek, Zhang, Jianhua, Zhang, Xiao-Dong, Zimetbaum, Peter

Source: In Zipes and Jalife's Cardiac Electrophysiology Edition: Eighth Edition. 2022:vii-xix

Sirtuins Positively Regulate KATP Channels, Which Contributes to their Cardioprotective Role

Authors: Tuncay, Erkan, Yang, Hua-Qian, Gando, Ivan, Turan, Belma, Ramasamy, Ravichandran, Coetzee, William A.

Source: Biophysical journal. 116(S1):250a-250a

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100076351785.0x000001&indx=1&recIds=ETOCvdc_100076351785.0x000001

Functional significance of channelopathy gene variants in unexplained death.

Authors: Gando, Ivan¹ (AUTHOR), Yang, Hua-Qian¹ (AUTHOR), Coetzee, William A.^1,2,3 (AUTHOR) william.coetzee@nyu.edu

Source: Forensic Science, Medicine & Pathology. Sep2019, Vol. 15 Issue 3, p437-444. 8p.

Subject Terms: *CO-sleeping, *AUTOPSY, *GENES, *SUDDEN infant death syndrome, *GENETIC testing, *DEATH

Population-Based Mathematical Modeling to Deduce Disease-Causing Cardiac Na+ Channel Gating Defects

Authors: Campana, Chiara, Gando, Ivan, Bianca Tan, Reina, Cecchin, Frank, Coetzee, William A., Sobie, Eric A.

Source: In Biophysical Journal 2 February 2018 114(3) Supplement 1:634a-635a

KATPchannels contribute to NK cell cytotoxicity

Authors: Samper, Natalie, Gando, Ivan, Wang, Liwei, Tao, Anthony, Feske, Stefan, Coetzee, William A.

Source: Biophysical Journal; February 2023, Vol. 122 Issue: 3, Number 3 Supplement 1 p523a-524a, 2p

A novel KIR-specific KATPchannel opener

Authors: Gando, Ivan, Becerra-Flores, Manuel, Chen, I-Shan, Yang, Hua-Qian, Shyng, Show-Ling, Nakamura, Tomoe Y., Cardozo, Timothy J., Coetzee, William A.

Source: Biophysical Journal; February 2023, Vol. 122 Issue: 3, Number 3 Supplement 1 p257a-257a, 1p