BacMam production and crystal structure of nonglycosylated apo human furin at 1.89 Å resolution

Authors: Pearce, Kenneth H., Overton, Laurie K., Gampe, Robert T., Barrett, George B., Taylor, J. David, McKee, David D., Campobasso, Nino, Nolte, Robert T., Reid, Robert A.

Source: Acta crystallographica.Section F.Structural biology communications. 75(4):239-245

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083089476.0x000001&indx=1&recIds=ETOCvdc_100083089476.0x000001

Structural Determinants of Ligand Binding Selectivity between the Peroxisome Proliferator-Activated Receptors

Authors: Xu, H. Eric, Lambert, Millard H., Montana, Valerie G., Plunket, Kelli D., Moore, Linda B., Collins, Jon L., Oplinger, Jeffery A., Kliewer, Steven A., Gampe, Robert T., McKee, David D., Moore, John T., Willson, Timothy M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2001 Nov . 98(24), 13919-13924.

Access URL: https://www.jstor.org/stable/3057195

Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors

Authors: Davis, Stephen T., Benson, Bill G., Bramson, H. Neal, Chapman, Dennis E., Dickerson, Scott H., Dold, Karen M., Eberwein, Derek J., Edelstein, Mark, Frye, Stephen V., Gampe, Robert T., Griffin, Robert J., Harris, Philip A., Hassell, Anne M., Holmes, William D., Hunter, Robert N., Knick, Victoria B., Lackey, Karen, Lovejoy, Brett, Luzzio, Michael J., Murray, Doris, Parker, Patricia, Rocque, Warren J., Shewchuk, Lisa, Veal, James M., Walker, Duncan H., Kuyper, Lee F.

Source: Science, 2001 Jan 01. 291(5501), 134-137.

Access URL: https://www.jstor.org/stable/3082192

A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1, 2-a]pyridine-6-carboxamide H-PGDS inhibitors

Authors: Schulte, Christie A., Deaton, David N., Diaz, Elsie, Do, Young, Gampe, Robert T., Guss, Jeffrey H., Hancock, Ashley P., Hobbs, Heather, Hodgson, Simon T., Holt, Jason, Jeune, Michael R., Kahler, Kirsten M., Kramer, H. Fritz, Le, Joelle, Mortenson, Paul N., Musetti, Caterina, Nolte, Robert T., Orband-Miller, Lisa A., Peckham, Gregory E., Petrov, Kim G., Pietrak, Beth L., Poole, Chuck, Price, Daniel J., Saxty, Gordon, Shillings, Anthony, Smalley, Terrence L., Somers, Don O., Stewart, Eugene L., Stuart, J. Darren, Thomson, Stephen A.

Source: Bioorganic & medicinal chemistry letters. 47

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134252871.0x000001&indx=1&recIds=ETOCvdc_100134252871.0x000001

A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors

Authors: Schulte, Christie A., Deaton, David N., Diaz, Elsie, Do, Young, Gampe, Robert T., Guss, Jeffrey H., Hancock, Ashley P., Hobbs, Heather, Hodgson, Simon T., Holt, Jason, Jeune, Michael R., Kahler, Kirsten M., Kramer, H. Fritz, Le, Joelle, Mortenson, Paul N., Musetti, Caterina, Nolte, Robert T., Orband-Miller, Lisa A., Peckham, Gregory E., Petrov, Kim G., Pietrak, Beth L., Poole, Chuck, Price, Daniel J., Saxty, Gordon, Shillings, Anthony, Smalley, Terrence L., Jr., Somers, Don O., Stewart, Eugene L., Stuart, J. Darren, Thomson, Stephen A.

Source: In Bioorganic & Medicinal Chemistry Letters 1 September 2021 47

Modulation of Androgen Receptor Activation Function 2 by Testosterone and Dihydrotestosterone

Authors: Askew, Emily B., Gampe, Robert T., Jr., Stanley, Thomas B., Faggart, Jonathan L., Wilson, Elizabeth M. ^**

Source: In Journal of Biological Chemistry 31 August 2007 282(35):25801-25816

Probing the Functional Link between Androgen Receptor Coactivator and Ligand-binding Sites in Prostate Cancer and Androgen Insensitivity

Authors: He, Bin ^{‡, 1}, Gampe, Robert T., Jr. ^§, Hnat, Andrew T. ^‡, Faggart, Jonathan L. ^‡, Minges, John T. ^‡, French, Frank S. ^‡, Wilson, Elizabeth M. ^{‡, 2}

Source: In Journal of Biological Chemistry 10 March 2006 281(10):6648-6663

Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix.

Authors: Gampe, Robert T. Jr, Montana, Valerie G., Lambert, Millard H.

Source: Genes & Development; September 1 2000, Vol. 14 Issue 17, p2229-2241, 13p

Total assignment of the 13C NMR spectrum of the cembranoid diterpene eunicin through the use of two-dimensional proton-carbon chemical shift correlation.

Authors: Gampe, Robert T. Jr, Alam, Maktoob, Weinheimer, Alfred J.

Source: Journal of the American Chemical Society; March 21 1984, Vol. 106, p1823-1826, 4p

Structural Basis for Androgen Receptor Interdomain and Coactivator Interactions Suggests a Transition in Nuclear Receptor Activation Function Dominance

Authors: He, Bin, Gampe, Robert T., Jr., Kole, Adam J., Hnat, Andrew T., Stanley, Thomas B., An, Gang, Stewart, Eugene L., Kalman, Rebecca I., Minges, John T., Wilson, Elizabeth M. ^*

Source: In Molecular Cell 2004 16(3):425-438

Catalytic activity of the SH2 domain of human pp60c-src; evidence from NMR, mass spectrometry, site-directed mutagenesis and kinetic studies for an inherent phosphatase activity.

Authors: Boerner, Renee J., Consler, Thomas G., Gampe, Robert T. Jr

Source: Biochemistry; November 21 1995, Vol. 34, p15351-15358, 8p

Asymmetry in the PPARγ/RXRα Crystal Structure Reveals the Molecular Basis of Heterodimerization among Nuclear Receptors

Authors: Gampe, Robert T., Jr., Montana, Valerie G., Lambert, Millard H., Miller, Aaron B., Bledsoe, Randy K., Milburn, Michael V., Kliewer, Steven A., Willson, Timothy M., Xu, H.Eric ^*

Source: In Molecular Cell March 2000 5(3):545-555

Retraction

Authors: Davis, Stephen T., Benson, Bill G., Bramson, H. Neal, Chapman, Dennis E., Dickerson, Scott H., Dold, Karen M., Eberwein, Derek J., Edelstein, Mark, Frye, Stephen V., Gampe, Robert T., Griffin, Robert J., Harris, Philip A., Hassell, Anne M., Holmes, William D., Hunter, Robert N., Knick, Victoria B., Lackey, Karen, Lovejoy, Brett, Luzzio, Michael J., Murray, Doris, Parker, Patricia, Rocque, Warren J., Shewchuk-Chapman, Lisa, Veal, James M., Walker, Duncan H., Kuyper, Lee F.

Source: Science, 2002 Dec . 298(5602), 2327-2327.

Access URL: https://www.jstor.org/stable/3833156

Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction.

Authors: Phelan, Caroline A.¹, Gampe, Robert T.², Lambert, Millard H.², Parks, Derek J.³, Montana, Valerie², Bynum, Jane³, Broderick, Timothy M.³, Xiao Hu¹, Williams, Shawn P.², Nolte, Robert T.² robert.t.nolte@gsk.com, Lazar, Mitchell A.¹ lazar@mail.med.upenn.edu

Source: Nature Structural & Molecular Biology. Jul2010, Vol. 17 Issue 7, p808-814. 7p. 4 Diagrams, 1 Chart, 1 Graph.

Subject Terms: *GENETIC transcription, *NUCLEAR receptors (Biochemistry), *CIRCADIAN rhythms, *HEMOPROTEINS, *LEWY body dementia

Heteronuclear three-dimensional NMR spectroscopy. Natural abundance 13C chemical shift editing of 1H-1H COSY spectra.

Authors: Fesik, Stephen W., Gampe, Robert T. Jr, Zuiderweg, Erik R. P.

Source: Journal of the American Chemical Society; January 18 1989, Vol. 111, p770-772, 3p

Synthesis and biological activities of novel indole derivatives as potent and selective PPARγ modulators

Authors: Lamotte, Yann, Martres, Paul, Faucher, Nicolas, Laroze, Alain, Grillot, Didier, Ancellin, Nicolas, Saintillan, Yannick, Beneton, Véronique, Gampe, Robert T., Jr.

Source: In Bioorganic & Medicinal Chemistry Letters 2010 20(4):1399-1404

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?

Authors: Adkison, Kim K., Barrett, David G., Deaton, David N., Gampe, Robert T., Hassell, Anne M., Long, Stacey T., McFadyen, Robert B., Miller, Aaron B., Miller, Larry R., Payne, J. Alan, Shewchuk, Lisa M., Wells-Knecht, Kevin J., Willard, Derril H., Jr., Wright, Lois L.

Source: In Bioorganic & Medicinal Chemistry Letters 2006 16(4):978-983

This result is not displayed to guests.
Login for full access.