Safety and Patient-Reported outcomes of atezolizumab plus chemotherapy with or without bevacizumab in stage IIIB/IV non-squamous non-small cell lung cancer with EGFR mutation, ALK rearrangement or ROS1 fusion progressing after targeted therapies (GFPC 06–2018 study)

Authors: Amari, Lyria, Tomasini, Pascale, Dantony, Emmanuelle, Rousseau-Bussac, Gaelle, Ricordel, Charles, Bigay-Game, Laurence, Arpin, Dominique, Morel, Hugues, Veillon, Remi, Justeau, Grégoire, Huchot, Eric, Fournel, Pierre, Vergnenegre, Alain, Bizeux, Acya, Subtil, Fabien, Clarisse, Bénédicte, Decroisette, Chantal, Chouaid, Christos, Greillier, Laurent, Bylicki, Olivier

Source: In Lung Cancer July 2024 193

Atezolizumab with or without bevacizumab and platinum-pemetrexed in patients with stage IIIB/IV non-squamous non-small cell lung cancer with EGFR mutation, ALK rearrangement or ROS1 fusion progressing after targeted therapies: A multicentre phase II open-label non-randomised study GFPC 06-2018

Authors: Bylicki, Olivier, Tomasini, Pascale, Radj, Gervais, Guisier, Florian, Monnet, Isabelle, Ricordel, Charles, Bigay-Game, Laurence, Geier, Margaux, Chouaid, Christos, Daniel, Catherine, Swalduz, Aurelie, Toffart, Anne-Claire, Doubre, Helene, Peloni, Jean-Michel, Moreau, Diane, Subtil, Fabien, Grellard, Jean-Michel, Castera, Marie, Clarisse, Benedicte, Martins-Lavinas, Pedro-Henrique, Decroisette, Chantal, Greillier, Laurent

Source: European journal of cancer. 183:38-48

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Injury primes mutation-bearing astrocytes for dedifferentiation in later life

Authors: Simpson Ragdale, Holly, Clements, Melanie, Tang, Wenhao, Deltcheva, Elitza, Andreassi, Catia, Lai, Alvina G., Chang, Wai Hoong, Pandrea, Maria, Andrew, Ivan, Game, Laurence, Uddin, Imran, Ellis, Michael, Enver, Tariq, Riccio, Antonella, Marguerat, Samuel, Parrinello, Simona

Source: In Current Biology 27 March 2023 33(6):1082-1098

Management of patients with synchronous head-and-neck and lung cancers: SYNCHRON GFPC 15-01 study

Authors: Paleiron, Nicolas, Gervais, Radj, Rousseau-Bussac, Gaelle, Game, Laurence, Chiappa, Anne, Lamy, Regine, Guisier, Florian, Le Caer, Hervé, Robinet, Gilles, Bizieux, Acya, Chouaïd, Christos

Source: Journal of Cancer Research and Therapeutics. 18(9):160-164

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167885935.0x000001&indx=1&recIds=ETOCvdc_100167885935.0x000001

PECATI: A Multicentric, Open-Label, Single-Arm Phase II Study to Evaluate the Efficacy and Safety of Pembrolizumab and Lenvatinib in Pretreated B3-Thymoma and Thymic Carcinoma Patients

Authors: Remon, Jordi, Girard, Nicolas, Novello, Silvia, de Castro, Javier, Bigay-Game, Laurence, Bernabé, Reyes, Greillier, Laurent, Mosquera, Joaquin, Cousin, Sophie, Juan, Oscar, Sampayo, Miguel, Besse, Benjamin

Source: Clinical lung cancer. 23(3):e243-e246

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165206037.0x000001&indx=1&recIds=ETOCvdc_100165206037.0x000001

Treatment strategies for thymic carcinoma in a real-life setting. Insights from the RYTHMIC network

Authors: Petat, Arthur, Dansin, Eric, Calcagno, Fabien, Greillier, Laurent, Pichon, Eric, Kerjouan, Mallorie, Clement-Duchene, Christelle, Mennecier, Bertrand, Westeel, Virginie, Thillays, François, Quantin, Xavier, Oulkhouir, Youssef, Thiberville, Luc, Ricordel, Charles, Thomas De Montpreville, Vincent, Chalabreysse, Lara, Hofman, Véronique, Molina, Thierry, Fournel, Pierre, Bigay Game, Laurence, Besse, Benjamin, Girard, Nicolas

Source: European journal of cancer. 162:118-127

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154776109.0x000001&indx=1&recIds=ETOCvdc_100154776109.0x000001

Prospective Multicenter Validation of the Detection of ALK Rearrangements of Circulating Tumor Cells for Noninvasive Longitudinal Management of Patients With Advanced NSCLC

Authors: Israel-Biet, Dominique, Pison, Christophe, Moro-Sibilot, Denis, Lantuejoul, Sylvie, Stephanov, Olivier, Juliette, Meyzenc, Mendozat, Christophe, Zaidi, Manel, Coulouvrat, Sandra, Col, Edwige, Chanez, Pascal, Greillier, Laurent, Tomasini, Pascale, Barlesi, Fabrice, Mascaux, Céline, Jourdan, Sandrine, Roger, Aurélie, Biemar, Julie, Randriamampionona, Rondro, Chabot, François, Tiotiu, Angélica, Clement-Duchene, Christelle, Vignaud, Jean-Michel, Lacomme, Stéphanie, Lomazzi, Sandra, Laurent, Carine, Bulsei, Xavier, Bischoff, Laura, Rakotonirina, Raymond, Layouni, Mehdi, Deslee, Gaëtan, Mal, Hervé, Kessler, Romain, Vergnon, Jean-Michel, Pelissier, Isabelle, Cuvelier, Antoine, Bourdin, Arnaud, Jounieaux, Vincent, Roche, Nicolas, Jouneau, Stéphane, Bonniaud, Philippe, Scherpereel, Arnaud, Mornex, Jean François, Steenhouwer, François, Leroy, Sylvie, Marquette, Charles Hugo, Benzaquen, Jonathan, Mazzette, Andrea, Padovani, Bernard, Hofman, Paul, Ilié, Marius, Hofman, Véronique, Fayada, Julien, Long-Mira, Elodie, Lassalle, Sandra, Pradelli, Johanna, Martinez, Estelle, Habault, Marine, Bonnard, Mélanie, Moutarde, Julie, Yatimi, Rachida, Labsi, Hakima, Gazoppi, Loïc, Lpce, Tumorothèque, Griffonnet, Jennifer, Fontaine, Maureen, Guillemart, Ariane, Butori, Catherine, Selva, Eric, Poudenx, Michel, Otto, Josiane, Hebert, Christophe, Botchiellini, Delphine, Boudouf, Soukaina, Menier, Margaux, Occeli, Estelle, Bellentani, Sophie, Pion, Carine, Fournier, Elodie, Thariat, Juliette, Gervais, Radj, Hamond, Karim, Marchand-Adam, Sylvain, Plantier, Laurent, Fajolle, Gaelle, Rayez, Mélanie, Cadranel, Jacques, Fallet, Vincent, Wislez, Marie, Antoine, Martine, Cote, Jean-François, Chaabane, Nouha, Ruppert, Anne Marie, Bertrand, Eliane, Rodenas, Anita, Pontdeme, Gwenaëlle, Mathiot, Nathalie, Ribert, Tamazouzt, Mazières, Julien, Guibert, Nicolas, Rouviere, Damien, Bousquet, Emilie, Bigay-Game, Laurence, Hermant, Christophe, Plat, Gavin, Rouquette, Isabelle, Evrard, Solène, Gouin, Sandrine, Clermont, Estelle Taranchon, Dormoy, Inge, Coulomb, Christelle, Pradine, Anne, Lambert, Véronique, Laborde, Lilian, Castelnau, Olivier, Chamorey, Emmanuel, Heeke, Simon, Thamphya, Brice, Boutros, Jacques, Clément-Duchêne, Christelle, Marquette, Charles-Hugo

Source: In Journal of Thoracic Oncology May 2021 16(5):807-816

Lung cancer survivors and employment: A systematic review

Authors: Vayr, Flora, Savall, Frédéric, Bigay-Game, Laurence, Soulat, Jean-Marc, Chouaid, Christos, Herin, Fabrice

Source: In Lung Cancer May 2019 131:31-39

Incidence of thyroid dysfunctions during treatment with nivolumab for non-small cell lung cancer: Retrospective study of 105 patients

Alternate Title: Incidence des effets indésirables thyroïdiens chez les patients ayant un cancer bronchique non à petites cellules au cours d’un traitement par nivolumab (French)

Authors: Campredon, Pauline, Mouly, Céline, Lusque, Amélie, Bigay-Game, Laurence, Bousquet, Emilie, Mazières, Julien, Caron, Philippe

Source: In La Presse Médicale April 2019 48(4):e199-e207

Continuous Infusion of Cilengitide Plus Chemoradiotherapy for Patients With Stage III Non–Small-cell Lung Cancer: A Phase I Study

Authors: Massabeau, Carole, Khalifa, Jonathan, Filleron, Thomas, Modesto, Anouchka, Bigay-Gamé, Laurence, Plat, Gavin, Dierickx, Lawrence, Aziza, Richard, Rouquette, Isabelle, Gomez-Roca, Carlos, Mounier, Muriel, Delord, Jean-Pierre, Toulas, Christine, Olivier, Pascale, Chatelut, Etienne, Mazières, Julien, Cohen-Jonathan Moyal, Elizabeth

Source: In Clinical Lung Cancer May 2018 19(3):e277-e285

Correction: Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within Minutes.

Authors: Mollet, Inês G., Patel, Dilipkumar, Govani, Fatima S., Giess, Adam, Paschalaki, Koralia, Periyasamy, Manikandan, Lidington, Elaine C., Mason, Justin C., Jones, Michael D., Game, Laurence, Ali, Simak, Shovlin, Claire L.

Source: PLoS ONE; 12/19/2024, Vol. 19 Issue 12, p1-3, 3p

Subject Terms: DNA repair, P53 protein, ENDOTHELIAL cells, STANDARD deviations, WESTERN immunoblotting

Single-cell imaging and RNA sequencing reveal patterns of gene expression heterogeneity during fission yeast growth and adaptation

Authors: Saint, Malika, Bertaux, François, Tang, Wenhao, Sun, Xi-Ming, Game, Laurence, Köferle, Anna, Bähler, Jürg, Shahrezaei, Vahid, Marguerat, Samuel

Source: Nature microbiology. 4(3):480-491

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130017296.0x000001&indx=1&recIds=ETOCvdc_100130017296.0x000001

Subclonal mutation selection in mouse lymphomagenesis identifies known cancer loci and suggests novel candidates

Authors: Webster, Philip, Dawes, Joanna, Dewchand, Hamlata, Takacs, Katalin, Iadarola, Barbara, Bolt, Bruce, Caceres, Juan, Kaczor, Jakub, Dharmalingam, Gopuraja, Dore, Marian, Game, Laurence, Adejumo, Thomas, Elliott, James, Naresh, Kikkeri, Karimi, Mohammad, Rekopoulou, Katerina, Tan, Ge, Paccanaro, Alberto, Uren, Anthony

Source: Nature communications. 9(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129121098.0x000001&indx=1&recIds=ETOCvdc_100129121098.0x000001

Safety of oral hydration after cisplatin infusion in an outpatient lung cancer unit

Authors: Puisset, Florent, Bigay-Game, Laurence, Paludetto, Marie Noëlle, Martel, Audrey, Perriat, Sophie, Rabeau, Audrey, Canonge, Jean Marie, Mazieres, Julien

Source: Supportive care in cancer. 27(5):1679-1686

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125295748.0x000001&indx=1&recIds=ETOCvdc_100125295748.0x000001

Three-Year Overall Survival of Patients With Advanced Non–Small-Cell Lung Cancers With ≥50% PD-L1 Expression Treated With First-Line Pembrolizumab Monotherapy in a Real-World Setting (ESCKEYP GFPC Study).

Authors: Decroisette, Chantal, Greillier, Laurent, Curcio, Hubert, Pérol, Maurice, Ricordel, Charles, Auliac, Jean-Bernard, Falchero, Lionel, Veillon, Remi, Vieillot, Sabine, Guisier, Florian, Marcq, Marie, Justeau, Grégoire, Bigay-Game, Laurence, Bernardi, Marie, Doubre, Hélène, Pinsolle, Julian, Amrane, Karim, Chouaïd, Christos, Descourt, Renaud

Source: Journal of Immunotherapy; Jan2024, Vol. 47 Issue 1, p16-20, 5p

Brief Report: Severe Sotorasib-Related Hepatotoxicity and Non-Liver Adverse Events Associated With Sequential Anti–Programmed Cell Death (Ligand)1 and Sotorasib Therapy in KRASG12C-Mutant Lung Cancer

Authors: Chour, Ali, Denis, Julie, Mascaux, Céline, Zysman, Maeva, Bigay-Game, Laurence, Swalduz, Aurélie, Gounant, Valérie, Cortot, Alexis, Darrason, Marie, Fallet, Vincent, Auclin, Edouard, Basse, Clémence, Tissot, Claire, Decroisette, Chantal, Bombaron, Pierre, Giroux-Leprieur, Etienne, Odier, Luc, Brosseau, Solenn, Creusot, Quentin, Gueçamburu, Marina, Meersseman, Corentin, Rochand, Adrien, Costantini, Adrien, Gaillard, Claire Marine, Wasielewski, Eric, Girard, Nicolas, Cadranel, Jacques, Lafitte, Claire, Lebossé, Fanny, Duruisseaux, Michaël

Source: In Journal of Thoracic Oncology October 2023 18(10):1408-1415

Kcnn4 Is a Regulator of Macrophage Multinucleation in Bone Homeostasis and Inflammatory Disease

Authors: Kang, Heeseog, Kerloc’h, Audrey, Rotival, Maxime, Xu, Xiaoqing, Zhang, Qing, D’Souza, Zelpha, Kim, Michael, Scholz, Jodi Carlson, Ko, Jeong-Hun, Srivastava, Prashant K., Genzen, Jonathan R., Cui, Weiguo, Aitman, Timothy J., Game, Laurence, Melvin, James E., Hanidu, Adedayo, Dimock, Janice, Zheng, Jie, Souza, Donald, Behera, Aruna K., Nabozny, Gerald, Cook, H. Terence, Bassett, J.H. Duncan, Williams, Graham R., Li, Jun, Vignery, Agnès, Petretto, Enrico, Behmoaras, Jacques

Source: In Cell Reports 21 August 2014 8(4):1210-1224

Venous thrombotic events and impact on outcomes in patients treated with first-line single-agent pembrolizumab in PD-L1 ≥ 50% advanced non small cell lung cancer.

Authors: Doubre, Hélène, Greillier, Laurent, Justeau, Grégoire, Ricordel, Charles, Swalduz, Aurélie, Curcio, Hubert, Bylicki, Olivier, Auliac, Jean-Bernard, Guisier, Florian, Bigay-Game, Laurence, Bernardi, Marie, Pinsolle, Julian, Amrane, Karim, Decroisette, Chantal, Descourt, Renaud, Chouaid, Christos, Geier, Margaux

Source: Journal of Cancer Research & Clinical Oncology; Nov2023, Vol. 149 Issue 16, p15095-15102, 8p

Subject Terms: NON-small-cell lung carcinoma, PROGRAMMED death-ligand 1, PEMBROLIZUMAB

Geographic Terms: FRANCE

The use of next-generation sequencing in clinical diagnosis of familial hypercholesterolemia

Authors: Vandrovcova, Jana, Thomas, Ellen R.A., Atanur, Santosh S., Norsworthy, Penny J., Neuwirth, Clare, Tan, Yvonne, Kasperaviciute, Dalia, Biggs, Jennifer, Game, Laurence, Mueller, Michael, Soutar, Anne K., Aitman, Timothy J.

Source: In Genetics in Medicine December 2013 15(12):948-957

A randomised trial comparing preoperative to perioperative chemotherapy in early-stage non-small-cell lung cancer (IFCT 0002 trial)

Authors: Westeel, Virginie, Quoix, Elisabeth, Puyraveau, Marc, Lavolé, A., Braun, Denis, Laporte, Silvy, Bigay-Game, Laurence, Pujol, Jean-Louis, Ozenne, Gervais, Rivière, Alain, Douillard, Jean-Yves, Lebeau, Bernard, Debieuvre, Didier, Poudenx, Michel, David, Philippe, Molinier, Olivier, Zalcman, Gérard, Lemarié, Etienne, Morin, Franck, Depierre, Alain, Milleron, Bernard

Source: In European Journal of Cancer August 2013 49(12):2654-2664