Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation

Authors: Gastaldi, Simone, Rocca, Carmine, Gianquinto, Eleonora, Granieri, Maria Concetta, Boscaro, Valentina, Blua, Federica, Rolando, Barbara, Marini, Elisabetta, Gallicchio, Margherita, De Bartolo, Anna, Romeo, Naomi, Mazza, Rosa, Fedele, Francesco, Pagliaro, Pasquale, Penna, Claudia, Spyrakis, Francesca, Bertinaria, Massimo, Angelone, Tommaso

Subject Terms: Physics - Biological Physics, Physics - Medical Physics

Access URL: http://arxiv.org/abs/2309.07939

The curious case of type I interferon signaling in cancer

Authors: Chhipa, Abu Sufiyan, Boscaro, Valentina, Gallicchio, Margherita, Patel, Snehal

Source: In BBA - Reviews on Cancer November 2024 1879(6)

Novel NLRP3 inhibitor INF195: Low doses provide effective protection against myocardial ischemia/reperfusion injury

Authors: Gastaldi, Simone ^{a, 1}, Giordano, Magalì ^{b, 1}, Blua, Federica ^a, Rubeo, Chiara ^b, Boscaro, Valentina ^a, Femminò, Saveria ^b, Comità, Stefano ^b, Gianquinto, Eleonora ^a, Landolfi, Vanessa ^b, Marini, Elisabetta ^a, Gallicchio, Margherita ^a, Spyrakis, Francesca ^a, Pagliaro, Pasquale ^{b, c, ⁎, 2}, Bertinaria, Massimo ^{a, b, ⁎}, Penna, Claudia ^{b, c, 2}

Source: In Vascular Pharmacology September 2024 156

Discovery of a novel 1, 3, 4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation

Authors: Gastaldi, Simone, Rocca, Carmine, Gianquinto, Eleonora, Granieri, Maria Concetta, Boscaro, Valentina, Blua, Federica, Rolando, Barbara, Marini, Elisabetta, Gallicchio, Margherita, De Bartolo, Anna, Romeo, Naomi, Mazza, Rosa, Fedele, Francesco, Pagliaro, Pasquale, Penna, Claudia, Spyrakis, Francesca, Bertinaria, Massimo, Angelone, Tommaso

Source: European journal of medicinal chemistry. 257

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194170659.0x000001&indx=1&recIds=ETOCvdc_100194170659.0x000001

Portable Voltammetry: A Rapid and Efficient Technique for Determining UV Filters in Cosmetics: A Comparative Study with HPLC-PDA and HPLC-MS/MS.

Authors: Inaudi, Paolo, Perrucci, Miryam, Velocci, Francesco, Giacomino, Agnese, Boscaro, Valentina, Gallicchio, Margherita, Ugazio, Elena, Abollino, Ornella, Protti, Michele, Lumini, Nadia, Locatelli, Marcello, Mandrioli, Roberto, Mercolini, Laura

Source: Analytical Chemistry; 8/27/2024, Vol. 96 Issue 34, p14004-14010, 7p

EPR and photophysical characterization of six bioactive oxidovanadium(IV) complexes in the conditions of in vitro cell tests

Authors: Lovisari, Marta, Volpi, Giorgio, Marabello, Domenica, Cadamuro, Silvano, Deagostino, Annamaria, Diana, Eliano, Barge, Alessandro, Gallicchio, Margherita, Boscaro, Valentina, Ghibaudi, Elena

Source: In Journal of Inorganic Biochemistry May 2017 170:55-62

Cell Membrane Fragment-Wrapped Parenteral Nanoemulsions: A New Drug Delivery Tool to Target Gliomas.

Authors: Dianzani, Chiara, Bozza, Annalisa, Bordano, Valentina, Cangemi, Luigi, Ferraris, Chiara, Foglietta, Federica, Monge, Chiara, Gallicchio, Margherita, Pizzimenti, Stefania, Marini, Elisabetta, Muntoni, Elisabetta, Valsania, Maria Carmen, Battaglia, Luigi

Source: Cells (2073-4409); Apr2024, Vol. 13 Issue 7, p641, 22p

Subject Terms: GLIOMAS, CELL membranes, BLOOD-brain barrier, ION pairs, DRUGS, SURGICAL excision

Synthesis, characterization and cell viability test of six vanadyl complexes with acetylacetonate derivatives

Authors: Sgarbossa, Speranza, Diana, Eliano, Marabello, Domenica, Deagostino, Annamaria, Cadamuro, Silvano, Barge, Alessandro, Laurenti, Enzo, Gallicchio, Margherita, Boscaro, Valentina, Ghibaudi, Elena

Source: In Journal of Inorganic Biochemistry November 2013 128:26-37

Replacement of Normal with Mutant Alleles in the Genome of Normal Human Cells Unveils Mutation-Specific Drug Responses

Authors: Di Nicolantonio, Federica, Arena, Sabrina, Gallicchio, Margherita, Zecchin, Davide, Martini, Miriam, Flonta, Simona Emilia, Stella, Giulia Maria, Lamba, Simona, Cancelliere, Carlotta, Russo, Mariangela, Geuna, Massimo, Appendino, Giovanni, Fantozzi, Roberto, Medico, Enzo, Bardelli, Alberto

Source: Proceedings of the National Academy of Sciences of the United States of America, 2008 Dec . 105(52), 20864-20869.

Access URL: https://www.jstor.org/stable/25464999

Generation of endogenous hydrogen sulfide by cystathionine γ-lyase limits renal ischemia/reperfusion injury and dysfunction

Authors: Tripatara, Pinpat, SA Patel, Nimesh, Collino, Massimo, Gallicchio, Margherita, Kieswich, Julius, Castiglia, Sara, Benetti, Elisa, Stewart, Keith N, Brown, Paul AJ, Yaqoob, Mohammed M, Fantozzi, Roberto, Thiemermann, Christoph

Source: In Laboratory Investigation October 2008 88(10):1038-1048

Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: Effects of the PPAR-α agonist WY14643

Authors: Collino, Massimo, Aragno, Manuela, Mastrocola, Raffaella, Benetti, Elisa, Gallicchio, Margherita, Dianzani, Chiara, Danni, Oliviero, Thiemermann, Christoph, Fantozzi, Roberto

Source: In Free Radical Biology and Medicine 2006 41(4):579-589

Modulation of the oxidative stress and inflammatory response by PPAR-γ agonists in the hippocampus of rats exposed to cerebral ischemia/reperfusion

Authors: Collino, Massimo, Aragno, Manuela, Mastrocola, Raffaella, Gallicchio, Margherita, Rosa, Arianna Carolina, Dianzani, Chiara, Danni, Oliviero, Thiemermann, Christopher, Fantozzi, Roberto

Source: In European Journal of Pharmacology 2006 530(1):70-80

Inhibition of vascular endothelial growth factor receptor 2–mediated endothelial cell activation by Axl tyrosine kinase receptor

Authors: Gallicchio, Margherita ^*, Mitola, Stefania, Valdembri, Donatella, Fantozzi, Roberto, Varnum, Brian, Avanzi, Gian Carlo, Bussolino, Federico

Source: In Blood 1 March 2005 105(5):1970-1976

Regulation of Ca 2+ movements by cyclovirobuxine D in ECV304 endothelial cells

Authors: Grossini, Elena ^*, Avanzi, Giancarlo, Gallicchio, Margherita, Molinari, Claudio, Vacca, Giovanni, Bellomo, Giorgio

Source: In Pharmacological Research 2005 52(2):154-161

Effects of anti-inflammatory [1, 2, 4]triazolo[4, 3-a] [1, 8]naphthyridine derivatives on human stimulated PMN and endothelial cells: an in vitro study

Authors: Roma Giorgio, Di Braccio Mario, Gallicchio Margherita, Collino Massimo, Dianzani Chiara, Fantozzi Roberto

Source: Journal of Inflammation, Vol 3, Iss 1, p 4 (2006)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.journal-inflammation.com/content/3/1/4; https://doaj.org/toc/1476-9255

Access URL: https://doaj.org/article/7ae77a11f72844749bad3a31468d5e49

Molecular characterization of HHV-8 positive primary effusion lymphoma reveals pathogenetic and histogenetic features of the disease

Authors: Gaidano, Gianluca ^*, Capello, Daniela, Fassone, Lucia, Gloghini, Annunziata, Cilia, Anna Maria, Ariatti, Cristiano, Buonaiuto, Daniela, Vivenza, Daniela, Gallicchio, Margherita, Avanzi, Gian Carlo, Prat, Maria, Carbone, Antonino

Source: In Journal of Clinical Virology 2000 16(3):215-224

Substance P-induced cyclooxygenase-2 expression in human umbilical vein endothelial cells.

Authors: Gallicchio, Margherita¹ margherita.gallicchio@unito.it, Rosa, Arianna Carolina¹, Benetti, Elisa¹, Collino, Massimo¹, Dianzani, Chiara¹, Fantozzi, Roberto¹

Source: British Journal of Pharmacology. Mar2006, Vol. 147 Issue 6, p681-689. 9p. 2 Diagrams, 10 Graphs.

Subject Terms: *CYCLOOXYGENASE 2, *SUBSTANCE P, *UMBILICAL cord, *CELLS, *VEINS, *PROTEIN kinases

This result is not displayed to guests.
Login for full access.

Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3.

Authors: Lolli, Marco L., Carnovale, Irene M., Pippione, Agnese C., Wahlgren, Weixiao Y., Bonanni, Davide, Marini, Elisabetta, Zonari, Daniele, Gallicchio, Margherita, Boscaro, Valentina, Goyal, Parveen, Friemann, Rosmarie, Rolando, Barbara, Bagnati, Renzo, Adinolfi, Salvatore, Oliaro-Bosso, Simonetta, Boschi, Donatella

Source: ACS Medicinal Chemistry Letters; 2019, Vol. 10 Issue 4, p437-443, 7p

Analyzing Cysteine Site Neighbors in Proteins to Reveal Dimethyl Fumarate Targets.

Authors: Rosa, Arianna Carolina, Benetti, Elisa, Gallicchio, Margherita, Boscaro, Valentina, Cangemi, Luigi, Dianzani, Chiara, Miglio, Gianluca

Source: Proteomics; Feb2019, Vol. 19 Issue 4, p1-7, 7p