The interactions between host genome and gut microbiome increase the risk of psychiatric disorders: Mendelian randomization and biological annotation

Authors: Xiao, Liling, Liu, Siyi, Wu, Yulu, Huang, Yunqi, Tao, Shiwan, Liu, Yunjia, Tang, Yiguo, Xie, Min, Ma, Qianshu, Yin, Yubing, Dai, Minhan, Zhang, Mengting, Llamocca, Elyse, Gui, Hongsheng, Wang, Qiang

Source: In Brain Behavior and Immunity October 2023 113:389-400

MAP3K19 regulatory variation in populations with African ancestry may increase COVID-19 severity

Authors: Cheng, Zhongshan ^{1, 9, ∗}, Cai, Yi ², Zhang, Ke ³, Zhang, Jingxuan ⁴, Gui, Hongsheng ⁵, Luo, Yu-Si ⁶, Zhou, Jie ⁷, DeVeale, Brian ^{8, ∗∗}

Source: In iScience 15 September 2023 26(9)

Shifting as an executive function separate from updating and inhibition in old age: Behavioral and genetic evidence

Authors: Ma, Juanjuan, Tang, Lixu, Peng, Peng, Wang, Tengfei, Gui, Hongsheng, Ren, Xuezhu

Source: In Behavioural Brain Research 24 August 2023 452

Self-rated health as a predictor of hospitalizations in patients with bipolar disorder or major depressive disorder: A prospective cohort study of the UK Biobank

Authors: Zhao, Haoyu, Ma, Qianshu, Xie, Min, Huang, Yunqi, Liu, Yunjia, Song, Huan, Gui, Hongsheng, Li, Mingli, Wang, Qiang

Source: In Journal of Affective Disorders 15 June 2023 331:200-206

Impact of post-traumatic stress disorder symptoms, childhood adversities and stressful life events on depressive and anxiety symptoms: insights from the UK Biobank.

Authors: Ma, Qianshu, Xie, Min, Llamocca, Elyse, Luo, Yupeng, Xiao, Liling, Tang, Yiguo, Tao, Shiwan, Wu, Yulu, Huang, Yunqi, Yin, Yubing, Liu, Yunjia, Liu, Siyi, Deng, Renhao, Qiao, Chunxia, Wei, Menghan, Chen, Yang, Cai, Jia, Gui, Hongsheng, Wang, Qiang

Source: Frontiers in Psychiatry; 2025, p1-10, 10p

Subject Terms: LIFE change events, MENTAL depression, SYMPTOMS, ANXIETY, DATA analysis, POST-traumatic stress disorder

Geographic Terms: UNITED Kingdom

Survival Association of Angiotensin Inhibitors in Heart Failure With Reduced Ejection Fraction: Comparisons Using Self-Identified Race and Genomic Ancestry

Authors: Luzum, JASMINE A., EDOKOBI, OZIOMA, DORSCH, MICHAEL P., PETERSON, EDWARD, LIU, BIN, GUI, HONGSHENG, WILLIAMS, L. KEOKI, LANFEAR, DAVID E.

Source: In Journal of Cardiac Failure February 2022 28(2):215-225

Integrated Transcriptome Analysis Reveals Novel Molecular Signatures for Schizophrenia Characterization.

Authors: Ni, Tong^1,2, Sun, Yu³, Li, Zefeng¹, Tan, Tao⁴, Han, Wei^1,2, Li, Miao⁵, Zhu, Li^1,2, Xiao, Jing^1,2, Wang, Huiying^1,2, Zhang, Wenpei^1,2, Ma, Yitian^1,2, Wang, Biao⁶, Wen, Di⁷, Chen, Teng^1,2, Tubbs, Justin⁸, Zeng, Xiaofeng⁹, zengxiaofeng@kmmu.edu.cn, Yan, Jiangwei¹⁰, yanjw@sxmu.edu.cn, Gui, Hongsheng^11,12, hgui1@hfhs.org, Sham, Pak⁸, Guan, Fanglin^1,2,4, fanglingguan@163.com

Source: Advanced Science; 1/13/2025, Vol. 12 Issue 2, p1-13, 13p

Suppression tumorigenicity 2 (ST2) turbidimetric immunoassay compared to enzyme-linked immunosorbent assay in predicting survival in heart failure patients with reduced ejection fraction

Authors: Aurora, Lindsey, Peterson, Edward, Gui, Hongsheng, Zeld, Nicole, McCord, James, Pinto, Yigal, Cook, Bernard, Sabbah, Hani N., Keoki Williams, L., Snider, James, Lanfear, David E.

Source: In Clinica Chimica Acta November 2020 510:767-771

Editorial: Integrative genetics and multi-omics of complex human disorders.

Authors: Gui, Hongsheng, Lessard, Christopher J., Liu, Jinhui, Li, Miaoxin, Adrianto, Indra

Source: Frontiers in Genetics; 2025, p1-3, 3p

Subject Terms: GENETIC correlations, GENE expression, BIOLOGICAL systems, GENETIC variation, LOCUS (Genetics)

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma

Authors: Abe, Namiko, Abecasis, Goncalo, Albert, Christine, Palmer Allred, Nicholette (Nichole), Almasy, Laura, Alonso, Alvaro, Ament, Seth, Anderson, Peter, Anugu, Pramod, Applebaum-Bowden, Deborah, Arking, Dan, Arnett, Donna K., Ashley-Koch, Allison, Aslibekyan, Stella, Assimes, Tim, Auer, Paul, Avramopoulos, Dimitrios, Barnard, John, Barnes, Kathleen, Barr, R. Graham, Barron-Casella, Emily, Beaty, Terri, Becker, Diane, Becker, Lewis, Beer, Rebecca, Begum, Ferdouse, Beitelshees, Amber, Benjamin, Emelia, Bezerra, Marcos, Bielak, Larry, Bis, Joshua, Blackwell, Thomas, Blangero, John, Boerwinkle, Eric, Borecki, Ingrid, Bowler, Russell, Brody, Jennifer, Broeckel, Ulrich, Broome, Jai, Bunting, Karen, Burchard, Esteban, Cardwell, Jonathan, Carty, Cara, Casaburi, Richard, Casella, James, Chaffin, Mark, Chang, Christy, Chasman, Daniel, Chavan, Sameer, Chen, Bo-Juen, Chen, Wei-Min, Chen, Yii-Der Ida, Cho, Michael H., Choi, Seung Hoan, Chuang, Lee-Ming, Chung, Mina, Cornell, Elaine, Correa, Adolfo, Crandall, Carolyn, Crapo, James, Cupples, L. Adrienne, Curran, Joanne, Curtis, Jeffrey, Custer, Brian, Damcott, Coleen, Darbar, Dawood, Das, Sayantan, David, Sean, Davis, Colleen, Daya, Michelle, de Andrade, Mariza, DeBaun, Michael, Deka, Ranjan, DeMeo, Dawn, Devine, Scott, Do, Ron, Duan, Qing, Duggirala, Ravi, Durda, Peter, Dutcher, Susan, Eaton, Charles, Ekunwe, Lynette, Ellinor, Patrick, Emery, Leslie, Farber, Charles, Farnam, Leanna, Fingerlin, Tasha, Flickinger, Matthew, Fornage, Myriam, Franceschini, Nora, Fu, Mao, Fullerton, Stephanie M., Fulton, Lucinda, Gabriel, Stacey, Gan, Weiniu, Gao, Yan, Gass, Margery, Gelb, Bruce, Geng, Xiaoqi (Priscilla), Germer, Soren, Gignoux, Chris, Gladwin, Mark, Glahn, David, Gogarten, Stephanie, Gong, Da-Wei, Goring, Harald, Gu, C. Charles, Guan, Yue, Guo, Xiuqing, Haessler, Jeff, Hall, Michael, Harris, Daniel, Hawley, Nicola, He, Jiang, Heavner, Ben, Heckbert, Susan, Hernandez, Ryan, Herrington, David, Hersh, Craig, Hidalgo, Bertha, Hixson, James, Hokanson, John, Holly, Kramer, Hong, Elliott, Hoth, Karin, (Agnes) Hsiung, Chao, Huston, Haley, Hwu, Chii Min, Irvin, Marguerite Ryan, Jackson, Rebecca, Jain, Deepti, Jaquish, Cashell, Jhun, Min A., Johnsen, Jill, Johnson, Andrew, Johnson, Craig, Johnston, Rich, Jones, Kimberly, Kachroo, Priyadarshini, Kang, Hyun Min, Kaplan, Robert, Kardia, Sharon, Kathiresan, Sekar, Kaufman, Laura, Kelly, Shannon, Kenny, Eimear, Kessler, Michael, Khan, Alyna, Kinney, Greg, Konkle, Barbara, Kooperberg, Charles, Krauter, Stephanie, Lange, Christoph, Lange, Ethan, Lange, Leslie, Laurie, Cathy, Laurie, Cecelia, LeBoff, Meryl, Lee, Seunggeun Shawn, Lee, Wen-Jane, LeFaive, Jonathon, Levine, David, Levy, Dan, Lewis, Joshua, Li, Yun, Lin, Honghuang, Lin, Keng Han, Liu, Simin, Liu, Yongmei, Loos, Ruth, Lubitz, Steven, Lunetta, Kathryn, Luo, James, Mahaney, Michael, Make, Barry, Manichaikul, Ani, Manson, JoAnn, Margolin, Lauren, Martin, Lisa, Mathai, Susan, Mathias, Rasika, McArdle, Patrick, McDonald, Merry-Lynn, McFarland, Sean, McGarvey, Stephen, Mei, Hao, Meyers, Deborah A., Mikulla, Julie, Min, Nancy, Minear, Mollie, Minster, Ryan L., Mitchell, Braxton, Montasser, May E., Musani, Solomon, Mwasongwe, Stanford, Mychaleckyj, Josyf C., Nadkarni, Girish, Naik, Rakhi, Natarajan, Pradeep, Nekhai, Sergei, Nickerson, Deborah, North, Kari, O'Connell, Jeff, O'Connor, Tim, Ochs-Balcom, Heather, Pankow, James, Papanicolaou, George, Parker, Margaret, Parsa, Afshin, Penchev, Sara, Peralta, Juan Manuel, Perez, Marco, Perry, James, Peters, Ulrike, Peyser, Patricia, Phillips, Lawrence S., Phillips, Sam, Pollin, Toni, Post, Wendy, Becker, Julia Powers, Boorgula, Meher Preethi, Preuss, Michael, Prokopenko, Dmitry, Psaty, Bruce, Qasba, Pankaj, Qiao, Dandi, Qin, Zhaohui, Rafaels, Nicholas, Raffield, Laura, Ramachandran, Vasan, Rao, D.C., Rasmussen-Torvik, Laura, Ratan, Aakrosh, Redline, Susan, Reed, Robert, Regan, Elizabeth, Reiner, Alex, Rice, Ken, Rich, Stephen, Roden, Dan, Roselli, Carolina, Rotter, Jerome, Ruczinski, Ingo, Russell, Pamela, Ruuska, Sarah, Ryan, Kathleen, Sakornsakolpat, Phuwanat, Salimi, Shabnam, Salzberg, Steven, Sandow, Kevin, Sankaran, Vijay, Scheller, Christopher, Schmidt, Ellen, Schwander, Karen, Schwartz, David, Sciurba, Frank, Seidman, Christine, Seidman, Jonathan, Sheehan, Vivien, Shetty, Amol, Shetty, Aniket, Sheu, Wayne Hui-Heng, Shoemaker, M. Benjamin, Silver, Brian, Silverman, Edwin, Smith, Jennifer, Smith, Josh, Smith, Nicholas, Smith, Tanja, Smoller, Sylvia, Snively, Beverly, Sofer, Tamar, Sotoodehnia, Nona, Stilp, Adrienne, Streeten, Elizabeth, Sung, Yun Ju, Su-Lasky, Jessica, Sylvia, Jody, Szpiro, Adam, Sztalryd, Carole, Taliun, Daniel, Tang, Hua, Taub, Margaret, Taylor, Kent, Taylor, Simeon, Telen, Marilyn, Thornton, Timothy A., Tinker, Lesley, Tirschwell, David, Tiwari, Hemant, Tracy, Russell, Tsai, Michael, Vaidya, Dhananjay, VandeHaar, Peter, Vrieze, Scott, Walker, Tarik, Wallace, Robert, Walts, Avram, Wan, Emily, Wang, Fei Fei, Watson, Karol, Weeks, Daniel E., Weir, Bruce, Weiss, Scott, Weng, Lu-Chen, Willer, Cristen, Williams, Kayleen, Williams, L. Keoki, Wilson, Carla, Wilson, James, Wong, Quenna, Xu, Huichun, Yanek, Lisa, Yang, Ivana, Yang, Rongze, Zaghloul, Norann, Zekavat, Maryam, Zhang, Yingze, Zhao, Snow Xueyan, Zhao, Wei, Zheng, Xiuwen, Zhi, Degui, Zhou, Xiang, Zody, Michael, Zoellner, Sebastian, Hecker, Julian, Chawes, Bo L., Ahluwalia, Tarunveer S., Kelly, Rachel S., Chu, Su H., Virkud, Yamini V., Huang, Mengna, Barnes, Kathleen C., Burchard, Esteban G., Eng, Celeste, Hu, Donglei, Celedón, Juan C., Levin, Albert M., Gui, Hongsheng, Forno, Erick, Mak, Angel C.Y., Avila, Lydiana, Soto-Quiros, Manuel E., Cloutier, Michelle M., Acosta-Pérez, Edna, Canino, Glorisa, Bønnelykke, Klaus, Bisgaard, Hans, Raby, Benjamin A., Weiss, Scott T., Lasky-Su, Jessica A.

Source: In Chest December 2019 156(6):1068-1079

Integrative approach identifies corticosteroid response variant in diverse populations with asthma

Authors: Levin, Albert M. ^∗, Gui, Hongsheng ^∗, Hernandez-Pacheco, Natalia, Yang, Mao, Xiao, Shujie, Yang, James J., Hochstadt, Samantha, Barczak, Andrea J., Eckalbar, Walter L., Rynkowski, Dean, Samedy, Lesly-Anne, Kwok, Pui-Yan, Pino-Yanes, Maria, Erle, David J., Lanfear, David E., Burchard, Esteban G., Williams, L. Keoki

Source: In The Journal of Allergy and Clinical Immunology May 2019 143(5):1791-1802

Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function

Authors: Lai, Frank Pui-Ling, Lau, Sin-Ting, Wong, John Kwong-Leong, Gui, Hongsheng, Wang, Reeson Xu, Zhou, Tingwen, Lai, Wing Hon, Tse, Hung-Fat, Tam, Paul Kwong-Hang, Garcia-Barcelo, Maria-Mercedes, Ngan, Elly Sau-Wai

Source: In Gastroenterology July 2017 153(1):139-153

Proteomic Response Predictor (PRP) For Beta Blocker Survival Benefit In Heart Failure Patients With Reduced Ejection Fraction

Authors: Venkateswaran, Vandana Revathi ¹, She, Ruicong ¹, Cabral, Whitney C ¹, Williams, L. Keoki ¹, Gui, Hongsheng ¹, Lanfear, David E ²

Source: In Journal of Cardiac Failure January 2025 31(1):265-265

Evaluation of a New Aptamer-Based Array for Soluble Suppressor of Tumorgenicity (ST2) and N-terminal Pro-B-Type Natriuretic Peptide (NTproBNP) in Heart Failure Patients.

Authors: Debbs, Joseph, Hannawi, Bashar, Peterson, Edward, Gui, Hongsheng, Zeld, Nicole, Luzum, Jasmine A., Sabbah, Hani N., Snider, James, Pinto, Yigal M., Williams, L. Keoki, Lanfear, David E.

Source: Journal of Cardiovascular Translational Research; Dec2023, Vol. 16 Issue 6, p1343-1348, 6p

Genome-Wide Association Study of Beta-Blocker Survival Benefit in Black and White Patients with Heart Failure with Reduced Ejection Fraction.

Authors: Luzum, Jasmine A., Campos-Staffico, Alessandra M., Li, Jia, She, Ruicong, Gui, Hongsheng, Peterson, Edward L., Liu, Bin, Sabbah, Hani N., Donahue, Mark P., Kraus, William E., Williams, L. Keoki, Lanfear, David E.

Source: Genes; Nov2023, Vol. 14 Issue 11, p2019, 11p

Subject Terms: GENOME-wide association studies, HEART failure patients, VENTRICULAR ejection fraction, SURVIVAL analysis (Biometry), PROPORTIONAL hazards models, GENETIC variation

Screening of the RET gene of Vietnamese Hirschsprung patients identifies 2 novel missense mutations

Authors: Ngo, Diem-Ngoc, So, Man-Ting, Gui, Hongsheng, Tran, Anh-Quynh, Bui, Duc-Hau, Cherny, Stacey, Tam, Paul Kwong-Hang, Nguyen, Thanh-Liem, Garcia-Barcelo, Maria-Mercè

Source: In Journal of Pediatric Surgery October 2012 47(10):1859-1864

15. GENETIC RELATIONSHIPS AND BIOLOGICAL PATHWAYS UNDERLYING SUICIDALITY AND COMORBID MENTAL DISORDERS: A COMPREHENSIVE CROSS-PHENOTYPE ANALYSIS

Authors: Gui, Hongsheng, Huang, Yunqi, Tao, Shiwan, Meng, Ze, Liu, Yunjia, Levin, Albert, Ahmedani, Brian, Wang, Qiang

Source: In European Neuropsychopharmacology October 2024 87 Supplement 1:55-55

Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed

Authors: Taub, Margaret A., Conomos, Matthew P., Keener, Rebecca, Iyer, Kruthika R., Weinstock, Joshua S., Yanek, Lisa R., Lane, John, Miller-Fleming, Tyne W., Brody, Jennifer A., Raffield, Laura M., McHugh, Caitlin P., Jain, Deepti, Gogarten, Stephanie M., Laurie, Cecelia A., Keramati, Ali, Arvanitis, Marios, Smith, Albert V., Heavner, Benjamin, Barwick, Lucas, Becker, Lewis C., Bis, Joshua C., Blangero, John, Bleecker, Eugene R., Burchard, Esteban G., Celedón, Juan C., Chang, Yen Pei C., Custer, Brian, Darbar, Dawood, de las Fuentes, Lisa, DeMeo, Dawn L., Freedman, Barry I., Garrett, Melanie E., Gladwin, Mark T., Heckbert, Susan R., Hidalgo, Bertha A., Irvin, Marguerite R., Islam, Talat, Johnson, W. Craig, Kaab, Stefan, Launer, Lenore, Lee, Jiwon, Liu, Simin, Moscati, Arden, North, Kari E., Peyser, Patricia A., Rafaels, Nicholas, Seidman, Christine, Weeks, Daniel E., Wen, Fayun, Wheeler, Marsha M., Williams, L. Keoki, Yang, Ivana V., Zhao, Wei, Aslibekyan, Stella, Auer, Paul L., Bowden, Donald W., Cade, Brian E., Chen, Zhanghua, Cho, Michael H., Cupples, L. Adrienne, Curran, Joanne E., Daya, Michelle, Deka, Ranjan, Eng, Celeste, Fingerlin, Tasha E., Guo, Xiuqing, Hou, Lifang, Hwang, Shih-Jen, Johnsen, Jill M., Kenny, Eimear E., Levin, Albert M., Liu, Chunyu, Minster, Ryan L., Naseri, Take, Nouraie, Mehdi, Reupena, Muagututi‘a Sefuiva, Sabino, Ester C., Smith, Jennifer A., Smith, Nicholas L., Lasky-Su, Jessica, Taylor, James G., VI, Telen, Marilyn J., Tiwari, Hemant K., Tracy, Russell P., White, Marquitta J., Zhang, Yingze, Wiggins, Kerri L., Weiss, Scott T., Vasan, Ramachandran S., Taylor, Kent D., Sinner, Moritz F., Silverman, Edwin K., Shoemaker, M. Benjamin, Sheu, Wayne H.-H., Sciurba, Frank, Schwartz, David A., Rotter, Jerome I., Roden, Daniel, Redline, Susan, Raby, Benjamin A., Psaty, Bruce M., Peralta, Juan M., Palmer, Nicholette D., Nekhai, Sergei, Montgomery, Courtney G., Mitchell, Braxton D., Meyers, Deborah A., McGarvey, Stephen T., Mak, Angel C.Y., Loos, Ruth J.F., Kumar, Rajesh, Kooperberg, Charles, Konkle, Barbara A., Kelly, Shannon, Kardia, Sharon L.R., Kaplan, Robert, He, Jiang, Gui, Hongsheng, Gilliland, Frank D., Gelb, Bruce D., Fornage, Myriam, Ellinor, Patrick T., de Andrade, Mariza, Correa, Adolfo, Chen, Yii-Der Ida, Boerwinkle, Eric, Barnes, Kathleen C., Ashley-Koch, Allison E., Arnett, Donna K., Albert, Christine, Laurie, Cathy C., Abecasis, Goncalo, Nickerson, Deborah A., Wilson, James G., Rich, Stephen S., Levy, Daniel, Ruczinski, Ingo, Aviv, Abraham, Blackwell, Thomas W., Thornton, Timothy, O’Connell, Jeff, Cox, Nancy J., Perry, James A., Armanios, Mary, Battle, Alexis, Pankratz, Nathan, Reiner, Alexander P., Mathias, Rasika A.

Source: In Cell Genomics 12 January 2022 2(1)

Examining sociodemographic correlates of opioid use, misuse, and use disorders in the All of Us Research Program.

Authors: Yeh, Hsueh-Han, Peltz-Rauchman, Cathryn, Johnson, Christine C., Pawloski, Pamala A., Chesla, David, Waring, Stephen C., Stevens, Alan B., Epstein, Mara, Joseph, Christine, Miller-Matero, Lisa R., Gui, Hongsheng, Tang, Amy, Boerwinkle, Eric, Cicek, Mine, Clark, Cheryl R., Cohn, Elizabeth, Gebo, Kelly, Loperena, Roxana, Mayo, Kelsey, Mockrin, Stephen

Source: PLoS ONE; 8/18/2023, Vol. 18 Issue 8, p1-9, 9p

Subject Terms: OPIOID analgesics, OPIOID abuse, NALTREXONE, OPIOIDS, ELECTRONIC health records, ETHNIC groups, LOGISTIC regression analysis

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