GSK3 acts as a switch for transcriptional programs in a model of low-grade gliomagenesis

Authors: Marilin S Koch, Minh Deo, Lena-Marie Schmitt, Michael S Hoetker, Şevin Turcan

Source: Acta Neuropathologica Communications, Vol 13, Iss 1, Pp 1-12 (2025)

Subject Terms: IDH mutation, Glioma, IDHmut-gliomagenesis, GSK3, WNT, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/260baeef2407401b882e982236521635

Subtherapeutic lithium supplementation causes physiological eccentric cardiac hypertrophy in young‐adult wild‐type male mice

Authors: Sophie I. Hamstra, Mia S. Geromella, Peter Tiidus, Panagiota Klentrou, Rebecca E. K. MacPherson, Val A. Fajardo

Source: Physiological Reports, Vol 13, Iss 7, Pp n/a-n/a (2025)

Subject Terms: cardiac function, eccentric hypertrophy, GSK3, lithium, SERCA, Physiology, QP1-981

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Relation: https://doaj.org/toc/2051-817X

Access URL: https://doaj.org/article/f6f1faff07f549df9b268a4b93785dc8

Melanocortin 5 receptor signaling protects against podocyte injury in proteinuric glomerulopathies

Authors: Chen, Bohan ^{1, ∗, 5, 6}, Chen, Mengxuan ^{1, 6}, Chang, Mingyang ^{1, 6}, Ge, Yan ¹, Gunning, William ², Assaly, Ragheb ³, Dworkin, Lance D. ^{1, 4}, Qiao, Ying Jin ^{1, ∗}, Gong, Rujun ^{1, 4, ∗}

Source: In Kidney International May 2025 107(5):835-851

FERONIA signaling maintains cell wall integrity during brassinosteroid-induced cell expansion in Arabidopsis

Authors: Chaudhary, Ajeet ^{1, ∗}, Hsiao, Yu-Chun ¹, Jessica Yeh, Fang-Ling ², Župunski, Milan ³, Zhang, Hongliang ¹, Aizezi, Yalikunjiang ^{1, 4}, Malkovskiy, Andrey ¹, Grossmann, Guido ³, Wu, Hen-Ming ², Cheung, Alice Y. ², Xu, Shou-Ling ¹, Wang, Zhi-Yong ^{1, ∗∗}

Source: In Molecular Plant 7 April 2025 18(4):603-618

A tale of two sugars: O-GlcNAc and O-fucose orchestrate growth, development, and acclimation in plants

Authors: Aizezi, Yalikunjiang ^{1, 2}, Yuan, Yizhong ¹, Xu, Shou-Ling ¹, Wang, Zhi-Yong ^{1, ⁎}

Source: In Trends in Biochemical Sciences April 2025 50(4):332-343

Inhibition of GSK3α,β rescues cognitive phenotypes in a preclinical mouse model of CTNNB1 syndrome

Authors: Jonathan M Alexander, Leeanne Vazquez-Ramirez, Crystal Lin, Pantelis Antonoudiou, Jamie Maguire, Florence Wagner, Michele H Jacob

Source: EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2109-2131 (2024)

Subject Terms: CTNNB1, β-Catenin, GSK3, Cognition, Motor, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/19f1b69be0b84f4cb9a069254536ee34

EXPLORING COMPARATIVELY THE CYTOTOXICITY OF MILLED AND 3D-PRINTED PMMA-BASED RESINS TO ORAL SQUAMOUS CANCER CELLS – WHAT SIGNALS COULD THE AKT/MTOR PATHWAY SEND US THROUGH ITS DOWNSTREAM EFFECTOR GSK-3?

Authors: Dan S. Enasescu, Bianca Voicu-Balasea, Florentina Rus-Hrincu, Radu Radulescu, Alexandra Popa, Mihai Radu Moisa, Bogdan-Ioan Coculescu, Marina Melescanu Imre, Silviu M. Pituru, Alexandra Ripszky

Source: Romanian Journal of Oral Rehabilitation, Vol 16, Iss 2, Pp 424-438 (2024)

Subject Terms: pmma-based, dental resin, akt/mtor, gsk3, apoptosis, maxillary obturator, Dentistry, RK1-715

File Description: electronic resource

Relation: https://rjor.ro/exploring-comparatively-the-cytotoxicity-of-milled-and-3d-printed-pmma-based-resins-to-oral-squamous-cancer-cells-what-signals-could-the-akt-mtor-pathway-send-us-through-its-downstream-effector-gsk/; https://doaj.org/toc/2066-7000; https://doaj.org/toc/2601-4661

Access URL: https://doaj.org/article/171a7a82e6ac442e9351d94fddd9fb05

PI3K/AKT signaling controls ICM maturation and proper epiblast and primitive endoderm specification in mice

Authors: Geiselmann, Anna ^{1, 2, 3, 7}, Micouin, Adèle ^{1, 3, 4, 7}, Vandormael-Pournin, Sandrine ^{1, 3}, Laville, Vincent ^{5, 6}, Chervova, Almira ¹, Mella, Sébastien ⁶, Navarro, Pablo ¹, Cohen-Tannoudji, Michel ^{1, 3, 8, ∗}

Source: In Developmental Cell 20 January 2025 60(2):204-219

Cilia as Wnt signaling organelles

Authors: Niehrs, Christof ^{1, 2, ⁎}, Da Silva, Fabio ^{1, 3}, Seidl, Carina ^{1, 4}

Source: In Trends in Cell Biology January 2025 35(1):24-32

The role of PI3K signaling pathway in Alzheimer’s disease

Authors: Jingying Pan, Qi Yao, Yankai Wang, Suyan Chang, Chenlong Li, Yongjiang Wu, Jianhong Shen, Riyun Yang

Source: Frontiers in Aging Neuroscience, Vol 16 (2024)

Subject Terms: Alzheimer’s disease, PI3K, tau protein, amyloid-β, Akt, GSK3, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2024.1459025/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/d88b3f114db34bb7bb86484b513114e3

Identification of GSK3 Family Genes in Pear and Their Expression Analysis Under Drought Stress

Authors: Kairan Hu, Ziyi Zhang, Guoliang Li, Shuliang Zhao, Yali Zhang, Qingjiang Wang, Fuhou Cheng

Source: Life, Vol 15, Iss 3, p 349 (2025)

Subject Terms: pear, GSK3, genome-wide, expression pattern, Science

File Description: electronic resource

Relation: https://www.mdpi.com/2075-1729/15/3/349; https://doaj.org/toc/2075-1729

Access URL: https://doaj.org/article/7b79e7fc4def402e989ebea82fa0f092

Glycogen synthase kinase 3 activity enhances liver inflammation in MASH

Authors: Khoury, Mireille ^{1, †}, Guo, Qianqian ^{1, †}, Furuta, Kunimaro ^{1, 2}, Correia, Cristina ³, Meroueh, Chady ⁴, Kim Lee, Hyun Se ¹, Warasnhe, Khaled ¹, Valenzuela-Pérez, Lucía ¹, Mazar, Andrew P. ⁵, Kim, Iljung ⁶, Noh, Yung-Kyun ^{6, 7}, Holmes, Heather ⁸, Romero, Michael F. ^{8, 9}, Sussman, Caroline R. ⁹, Pavelko, Kevin D. ¹⁰, Islam, Shahidul ¹, Bamidele, Adebowale O. ^{1, 11}, Hirsova, Petra ¹, Li, Hu ³, Ibrahim, Samar H. ^{1, 12, ⁎}

Source: In JHEP Reports June 2024 6(6)

Inhibition of mitochondrial cyclophilin D, a downstream target of glycogen synthase kinase 3α, improves sperm motility

Authors: Seung Hyun Park, Myung Chan Gye

Source: Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-11 (2024)

Subject Terms: GSK3, Cyclophilin D, Motility regulation, Spermatozoa, Mouse, Gynecology and obstetrics, RG1-991, Reproduction, QH471-489

File Description: electronic resource

Relation: https://doaj.org/toc/1477-7827

Access URL: https://doaj.org/article/ecf12106c2924e69b20eae16c5c226d4

Differential diagnosis of unipolar versus bipolar depression by GSK3 levels in peripheral blood: a pilot experimental study

Authors: Gianluca Rosso, Giuseppe Maina, Elena Teobaldi, Ilaria Balbo, Gabriele Di Salvo, Francesca Montarolo, Nicola Rizzo Pesci, Filippo Tempia, Eriola Hoxha

Source: International Journal of Bipolar Disorders, Vol 11, Iss 1, Pp 1-9 (2023)

Subject Terms: Bipolar disorders, Major depressive disorder, Differential diagnosis, Biomarker, GSK3, Depression, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurophysiology and neuropsychology, QP351-495

File Description: electronic resource

Relation: https://doaj.org/toc/2194-7511

Access URL: https://doaj.org/article/eb7df6b082ba4722b09b7911bacc50ad

Possible involvement of Interleukin‐17A in the deterioration of prepulse inhibition on acoustic startle response in mice

Authors: Chisato Wakabayashi, Hiroshi Kunugi

Source: Neuropsychopharmacology Reports, Vol 43, Iss 3, Pp 365-372 (2023)

Subject Terms: GSK3, IL‐17A, mouse, prepulse inhibition, sensorimotor gating, striatum, Therapeutics. Pharmacology, RM1-950, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2574-173X

Access URL: https://doaj.org/article/7bcaffb3fd4c40dcafd0ad0884cf9799

Sperm Quality: Past, Present and the Future Knowledge We Need

Contributors: Santolaria Blasco, Pilar, Pérez-Pe, Rosaura, Rickard, Jessica

Subject Terms: MACS, sperm, sperm selection, ICSI, cumulative live birth rate, pregnancy rate, cluster, sows, motility, CASA-Mot, artificial insemination, sperm capacitation, pig, bicarbonate, bovine serum albumin (BSA), glycogen synthase kinase (GSK3), protein kinase A (PKA), Bos taurus, spermiogram, male fertility, capacitation, acrosome reaction, rhino, viscous, freezing, conservation, flow cytometry, CASA, porcine, sperm conservation, ejaculate portions, sperm function, reproduction, litter performance, echotexture, ultrasound, Doppler, seasonality, testes, sperm performance, hamster, sperm motility, acrosome integrity, ATP content, Mesocricetus auratus, Cricetulus griseus, Phodopus sungorus, Phodopus roborovskii, Phodopus campbelli, sperm metabolic profile, turkey sperm cryopreservation, avian sperm, sperm NMR analysis, human spermatozoa, sperm proteins, PTM, phosphorylation, phosphoproteomics, male infertility, bull semen, sexing semen, magnetic-activated cell sorting, scFv antibody, semen quality, Research and information: general, Biology, life sciences

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/114001
https://mdpi.com/books/pdfview/book/7846

Inhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cells

Authors: Chinmai Patibandla, Lidy van Aalten, Albena T. Dinkova-Kostova, Tadashi Honda, Antonio Cuadrado, Raquel Fernández-Ginés, Alison D. McNeilly, John D. Hayes, James Cantley, Calum Sutherland

Source: Redox Biology, Vol 71, Iss , Pp 103117- (2024)

Subject Terms: NRF2, GSK3, β-TrCP, β cells, Islets, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231724000934; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/174bdfaa05484649a9d4e82ff51fecbf

Elraglusib (formerly 9-ING-41) possesses potent anti-lymphoma properties which cannot be attributed to GSK3 inhibition

Authors: Josh T. Coats, Sudhir Tauro, Calum Sutherland

Source: Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-7 (2023)

Subject Terms: Elraglusib, 9-ING-41, GSK3, Lymphoma, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/c6d05eb711b74cec9ec21be1f9bf415b

Dibutyl phthalate disrupts glycogen synthase kinase 3α essential for sperm motility

Authors: Seung Hyun Park, Myung Chan Gye

Source: Ecotoxicology and Environmental Safety, Vol 271, Iss , Pp 115977- (2024)

Subject Terms: Dibutyl phthalate, Inhibitory phosphorylation, Ubiquitination, GSK3, Motility, Mouse spermatozoa, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0147651324000526; https://doaj.org/toc/0147-6513

Access URL: https://doaj.org/article/16bc9f4050374139a9b7b184c14ef309

Somatostatin-SSTR3-GSK3 modulates human T-cell responses by inhibiting OXPHOS

Authors: Bo Zhang, Huiru Feng, Hui Lin, Rui Li

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: somatostatin (SST), T cells, somatostatin receptor 3 (SSTR3), mitochondrial respiration and glycogen synthase kinase-3 (GSK3), metabolism, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1322670/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/c59693366faf46c88b208bd267c88671