Identification of potential targets regulating neutrophil extracellular traps in acute rejection of kidney transplantation based on transcriptomics and animal experiments

Authors: Pei, Jun ^{a, 1}, Weng, Huali ^{b, 1}, Peng, Jinpu ^a, Wu, Moudong ^a, Zhan, Xiong ^a, Zhu, Guohua ^a, Wang, Dan ^a, Pan, Xingyu ^{a, ⁎}, An, Nini ^{a, ⁎}

Source: In International Immunopharmacology 6 February 2025 147

Mesenchymal Stem Cells with Simultaneous Overexpression of GPX3 and CD47 for the Treatment of Drug-Induced Acute Liver Injury

Authors: Yuanxiang Jing, Balun Li, Aili Aierken, Zengyu Zhang, Dongyao Han, Zixi Lin, Jiaqi Gao, Hongkai Tian, Jinlian Hua

Source: Veterinary Sciences, Vol 12, Iss 2, p 149 (2025)

Subject Terms: mesenchymal stem cells (MSCs), GPX3, CD47, drug-induced liver injury, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://www.mdpi.com/2306-7381/12/2/149; https://doaj.org/toc/2306-7381

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A novel selenoglycoside compound GlcSeCys alleviates diets-induced obesity and metabolic dysfunctions with the modulation of Galectin-1 and selenoproteins

Authors: Zhang, Ruhui ^{a, b}, Xie, Xinni ^{a, b, ⁎}, Liu, Jun ^{a, d}, Pan, Ruiying ^{a, b}, Huang, Yu ^{a, b}, Du, Yuguo ^{a, c, ⁎}

Source: In Life Sciences 15 December 2024 359

Selenoprotein GPX3 is a novel prognostic indicator for stomach adenocarcinoma and brain low-grade gliomas: Evidence from an integrative pan-cancer analysis

Authors: Wang, Yuetong ^a, Fu, Guotao ^b, Chen, Xueqin ^b, Xia, Zengrun ^c, Qi, Meng ^c, Du, Xiaoping ^c, Liu, Kun ^d, Liu, Qiling ^b, Sun, Na ^b, Shi, Chuandao ^b, Qu, Kai ^a, Zhang, Rongqiang ^{b, ⁎}

Source: In Heliyon 15 June 2024 10(11)

Oxidatively stressed extracellular microenvironment drives fibroblast activation and kidney fibrosis

Authors: Li Li, Meizhi Lu, Yiling Peng, Junxin Huang, Xiaoman Tang, Jian Chen, Jing Li, Xue Hong, Meizhi He, Haiyan Fu, Ruiyuan Liu, Fan Fan Hou, Lili Zhou, Youhua Liu

Source: Redox Biology, Vol 67, Iss , Pp 102868- (2023)

Subject Terms: Oxidative stress, Extracellular microenvironment, GPX3, Fibroblast activation, Kidney fibrosis, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231723002690; https://doaj.org/toc/2213-2317

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Comprehensive analysis identifies novel targets of gemcitabine to improve chemotherapy treatment strategies for colorectal cancer

Authors: Xinxin Zeng, Liyue Sun, Xiaomei Ling, Yuying Jiang, Ju Shen, Lei Liang, Xuhui Zhang

Source: Frontiers in Endocrinology, Vol 14 (2023)

Subject Terms: colorectal cancer, chemotherapy, gemcitabine, combination drug, CALB2, GPX3, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2023.1170526/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/2cdd2ee72ce3427587570681aebd3396

GPx3 knockdown inhibits the proliferation and DNA synthesis and enhances the early apoptosis of human spermatogonial stem cells via mediating CXCL10 and cyclin B1

Authors: Si Wu, Zixin Cheng, Ye Peng, Ying Cao, Zuping He

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: GPx3, CXCL10, cyclin B1, human spermatogonial stem cells, proliferation, apoptosis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.1213684/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/5420a7d45bba436bb222d2524b6bb83b

Increased expression of glutathione peroxidase 3 prevents tendinopathy by suppressing oxidative stress

Authors: Haruka Furuta, Mari Yamada, Takuya Nagashima, Shuichi Matsuda, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: real-world data, tendinopathy, fluoroquinolone, aging, dexamethasone, GPX3, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1137952/full; https://doaj.org/toc/1663-9812

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GPX3 and GSTT1 as biomarkers related to oxidative stress during renal ischemia reperfusion injuries and their relationship with immune infiltration

Authors: Jun Pei, Xiaomao Tian, Chengjun Yu, Jin Luo, Jie Zhang, Yi Hua, Guanghui Wei

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: oxidative stress, immune infiltration, ischemia-reperfusion injury, kidney, GPX3, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1136146/full; https://doaj.org/toc/1664-3224

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GPX3 expression was down-regulated but positively correlated with poor outcome in human cancers

Authors: Qingyi Hu, Jiaoshun Chen, Wen Yang, Ming Xu, Jun Zhou, Jie Tan, Tao Huang

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: GPX3, pan-cancer, glutathione peroxidase, chemotherapy resistance, metastasis, tumor microenvironment (TME), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.990551/full; https://doaj.org/toc/2234-943X

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GPX3 rs8177412 Polymorphism Modifies Risk of Upper Urothelial Tumors in Patients with Balkan Endemic Nephropathy

Authors: Zana Radic Savic, Vesna Coric, Stojko Vidovic, Vanja Vidovic, Jelena Becarevic, Irina Milovac, Zorica Reljic, Bosa Mirjanic-Azaric, Ranko Skrbic, Radoslav Gajanin, Marija Matic, Tatjana Simic

Source: Medicina, Vol 59, Iss 8, p 1421 (2023)

Subject Terms: Balkan endemic nephropathy, upper tract urothelial cell carcinoma, aristolochic acid, GPX3 polymorphism, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/1648-9144/59/8/1421; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144

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Reduced Expression of GPX3 in Breast Cancer Patients in Correlation with Clinical Significance

Authors: Pensri Saelee, Tanett Pongtheerat, Thanet Sophonnithiprasert

Source: Global Medical Genetics, Vol 07, Iss 03, Pp 087-091 (2020)

Subject Terms: breast cancer, gpx3, antioxidant enzyme, gene expression, real-time reverse transcription-pcr, Genetics, QH426-470, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2699-9404

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Overexpression of GPX3, a potential biomarker for diagnosis and prognosis of breast cancer, inhibits progression of breast cancer cells in vitro

Authors: Weiyang Lou, Bisha Ding, Shuqian Wang, Peifen Fu

Source: Cancer Cell International, Vol 20, Iss 1, Pp 1-15 (2020)

Subject Terms: Glutathione peroxidase 3 (GPX3), Breast cancer, Diagnosis, Prognosis, Biomarker, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12935-020-01466-7; https://doaj.org/toc/1475-2867

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GPX3 Overexpression in Cumulus Cells Entails a Poor Prognosis for Uterine Implantation of Morphotype A Embryos

Authors: Ignacio Bejarano, Mónica Dorado-Silva, Helia Sarmiento-Soto, Nuria Álvarez-Sánchez, Patricia Judith Lardone, Juan Miguel Guerrero, Pascual Sánchez-Martín, Antonio Carrillo-Vico

Source: Biology, Vol 11, Iss 9, p 1361 (2022)

Subject Terms: cumulus cells, implantation, GPX3, infertility, transcriptome, oocyte competence, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2079-7737/11/9/1361; https://doaj.org/toc/2079-7737

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Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity

Authors: Julia Langhardt, Gesine Flehmig, Nora Klöting, Stefanie Lehmann, Thomas Ebert, Matthias Kern, Michael R. Schön, Daniel Gärtner, Tobias Lohmann, Miriam Dressler, Mathias Fasshauer, Peter Kovacs, Michael Stumvoll, Arne Dietrich, Matthias Blüher

Source: Obesity Facts, Vol 11, Iss 6, Pp 475-490 (2018)

Subject Terms: Glutathione peroxidase 3 (GPX3), Obesity, Adipose tissue, Insulin resistance, Adipokines, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/494295; https://doaj.org/toc/1662-4025; https://doaj.org/toc/1662-4033

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GPX3 promoter methylation predicts platinum sensitivity in colorectal cancer

Authors: Lorraine Pelosof, Sashidhar Yerram, Todd Armstrong, Nina Chu, Ludmila Danilova, Breann Yanagisawa, Manuel Hidalgo, Nilofer Azad, James G. Herman

Source: Epigenetics, Vol 12, Iss 7, Pp 540-550 (2017)

Subject Terms: cisplatin, colorectal cancer, gpx3, methylation, oxaliplatin, Genetics, QH426-470

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Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

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Unconventional Targeting of a Thiol Peroxidase to the Mitochondrial Intermembrane Space Facilitates Oxidative Protein Folding

Authors: Paraskevi Kritsiligkou, Afroditi Chatzi, Georgia Charalampous, Aleksandr Mironov, Jr., Chris M. Grant, Kostas Tokatlidis

Source: Cell Reports, Vol 18, Iss 11, Pp 2729-2741 (2017)

Subject Terms: mitochondria, oxidative protein folding, mitochondria biogenesis, protein targeting, oxidative stress, antioxidants, alternative translation initiation, Mia40, Gpx3, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717302516; https://doaj.org/toc/2211-1247

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Xenopus gpx3 Mediates Posterior Development by Regulating Cell Death during Embryogenesis

Authors: Hongchan Lee, Tayaba Ismail, Youni Kim, Shinhyeok Chae, Hong-Yeoul Ryu, Dong-Seok Lee, Taeg Kyu Kwon, Tae Joo Park, Taejoon Kwon, Hyun-Shik Lee

Source: Antioxidants, Vol 9, Iss 12, p 1265 (2020)

Subject Terms: gpx3, tailbud, apoptosis, posterior development, embryogenesis, Therapeutics. Pharmacology, RM1-950

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Relation: https://www.mdpi.com/2076-3921/9/12/1265; https://doaj.org/toc/2076-3921

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A Low Glycemic Index Decreases Inflammation by Increasing the Concentration of Uric Acid and the Activity of Glutathione Peroxidase (GPx3) in Patients with Polycystic Ovary Syndrome (PCOS)

Authors: Małgorzata Szczuko, Marta Zapalowska-Chwyć, Radosław Drozd

Source: Molecules, Vol 24, Iss 8, p 1508 (2019)

Subject Terms: polycystic ovary syndrome, diet, antioxidant status, GPx3, uric acid, FRAP, Organic chemistry, QD241-441

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Relation: https://www.mdpi.com/1420-3049/24/8/1508; https://doaj.org/toc/1420-3049

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Hypermethylation, Loss of Expression of Glutathione Peroxidase-3 in Barrett's Tumorigenesis

Authors: Ok-Jae Lee, Regine Schneider-Stock, Patricia A. McChesney, Doerthe Kuester, Albert Roessner, Michael Vieth, Christopher A. Moskaluk, Wa'el El-Rifai

Source: Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 9, Pp 854-861 (2005)

Subject Terms: Barrett's, dysplasia, cancer, GPx3, ROS, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558605800077; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/961493c20a464892ba1daa5d2d072feb