Alterations in the Structure, Composition, and Organization of Galactosaminoglycan-Containing Proteoglycans and Collagen Correspond to the Progressive Stages of Dupuytren's Disease.

Authors: Lenzi, Luiz Guilherme S.¹ (AUTHOR) lenzilgs@gmail.com, Gomes dos Santos, João Baptista¹ (AUTHOR) joao.epm@hotmail.com, Cavalheiro, Renan P.^2,3 (AUTHOR) rpcavalheiro@gmail.com, Mendes, Aline² (AUTHOR) alina.mendess@gmail.com, Kobayashi, Elsa Y.² (AUTHOR) elsayoko@gmail.com, Nader, Helena B.² (AUTHOR) hbnader@unifesp.br, Faloppa, Flavio¹ (AUTHOR) faloppa.dot@unifesp.br

Source: International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 13, p7192. 17p.

Subject Terms: *GLYCOSAMINOGLYCANS, *LEUCINE, *ANTI-Stokes scattering, *PROTEOGLYCANS, *COLLAGEN, *DERMATAN sulfate, *CHONDROITIN sulfates, *GENE expression

Open clinical trial evaluating the efficacy of a novel eyelash growth enhancer with peptides and glycosaminoglycans.

Authors: Fernandez‐Gonzalez, Pablo¹ (AUTHOR) pabfergon@gmail.com, Truchuelo‐Díez, Maria Teresa² (AUTHOR), Gómez‐Sánchez, Maria José¹ (AUTHOR)

Source: Journal of Cosmetic Dermatology. Jun2024, Vol. 23 Issue 6, p2170-2180. 11p.

Subject Terms: *EYELASHES, *GLYCOSAMINOGLYCANS, *CLINICAL trials, *PATIENT satisfaction, *PEPTIDES

Glycosaminoglycan dermatan sulfate supplementation decreases diet‐induced obesity and metabolic dysfunction in mice.

Authors: Stojnić, Bojan^1,2 (AUTHOR), Galmés, Sebastiá^1,3,4 (AUTHOR), Serrano, Alba¹ (AUTHOR), Sulli, Maria² (AUTHOR), Sušak, Lana¹ (AUTHOR), Seye, Ndioba¹ (AUTHOR), Palou, Andreu^1,3,4 (AUTHOR), Diretto, Gianfranco² (AUTHOR), Bonet, M. Luisa^1,3,4 (AUTHOR) luisabonet@uib.es, Ribot, Joan^1,3,4 (AUTHOR)

Source: Biofactors. May2024, Vol. 50 Issue 3, p493-508. 16p.

Subject Terms: *GLYCOSAMINOGLYCANS, *DERMATAN sulfate, *METABOLIC disorders, *FAT, *BROWN adipose tissue, *OBESITY, *ADIPOSE tissues

The Role of Fibrogenesis and Extracellular Matrix Proteins in the Pathogenesis of Graves' Ophthalmopathy.

Authors: Chiu, Hsun-I^1,2 (AUTHOR), Wu, Shi-Bei³ (AUTHOR), Tsai, Chieh-Chih^1,2 (AUTHOR) cctsai@vghtpe.gov.tw

Source: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 6, p3288. 16p.

Subject Terms: *GLYCOSAMINOGLYCANS, *TISSUE remodeling, *THYROID eye disease, *NON-coding RNA, *EXTRACELLULAR matrix proteins, *ECTOPIC tissue, *PATHOGENESIS, *EXTRACELLULAR matrix

Melatonin inhibits the stemness of head and neck squamous cell carcinoma by modulating HA synthesis via the FOSL1/HAS3 axis.

Authors: Luo, Xinyue¹ (AUTHOR), Wang, Jingjing¹ (AUTHOR), Chen, Yang^1,2 (AUTHOR), Zhou, Xiaocheng^1,2 (AUTHOR), Shao, Zhe^1,3 (AUTHOR), Liu, Ke^1,3 (AUTHOR) liuke.1999@whu.edu.cn, Shang, Zhengjun^1,3 (AUTHOR) shangzhengjun@whu.edu.cn

Source: Journal of Pineal Research. Mar2024, Vol. 76 Issue 2, p1-15. 15p.

Subject Terms: *GLYCOSAMINOGLYCANS, *SQUAMOUS cell carcinoma, *CANCER stem cells, *MELATONIN, *HYALURONIC acid

Matrix Metalloproteinases in the Periodontium—Vital in Tissue Turnover and Unfortunate in Periodontitis.

Authors: Radzki, Dominik^1,2 (AUTHOR) dominik.radzki@gumed.edu.pl, Negri, Alessandro² (AUTHOR), Kusiak, Aida¹ (AUTHOR), Obuchowski, Michał² (AUTHOR)

Source: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 5, p2763. 33p.

Subject Terms: *MATRIX metalloproteinases, *GLYCOSAMINOGLYCANS, *PERIODONTIUM, *TISSUE inhibitors of metalloproteinases, *PERIODONTITIS, *PROTEOLYTIC enzymes, *PROTEOGLYCANS

Evaluation of GHK peptide–heparin interactions in multifunctional liposomal covering.

Authors: Nikolaeva, Viktoriia^1,2 (AUTHOR), Kamalov, Marat^1,2 (AUTHOR), Abdullin, Timur I.^1,2 (AUTHOR) tabdulli@gmail.com, Salakhieva, Diana^1,2 (AUTHOR), Chasov, Vitaly¹ (AUTHOR), Rogov, Alexey³ (AUTHOR), Zoughaib, Mohamed^1,2 (AUTHOR) mohamadzougheib@gmail.com

Source: Journal of Liposome Research. Mar2024, Vol. 34 Issue 1, p18-30. 13p.

Subject Terms: *HEPARIN, *GLYCOSAMINOGLYCANS, *INHIBITION of cellular proliferation, *CHEMICAL structure, *THERAPEUTIC use of proteins, *CELL anatomy, *LIPOSOMES

The Effect of Heparin and Other Exogenous Glycosaminoglycans (GAGs) in Reducing IL-1β-Induced Pro-Inflammatory Cytokine IL-8 and IL-6 mRNA Expression and the Potential Role for Reducing Inflammation.

Authors: Jafri, Murtaza¹ (AUTHOR) jafrim@myumanitoba.ca, Li, Lin² (AUTHOR) lin.li@phac-aspc.gc.ca, Liang, Binhua^2,3 (AUTHOR) ben.liang@phac-aspc.gc.ca, Luo, Ma^2,4 (AUTHOR) ma.luo@phac-aspc.gc.ca

Source: Pharmaceuticals (14248247). Mar2024, Vol. 17 Issue 3, p371. 10p.

Subject Terms: *GLYCOSAMINOGLYCANS, *GENE expression, *HEPARIN, *INTERLEUKIN-6, *CELL anatomy, *CYTOKINES

Meta‐analysis of in vitro methods on tracheal decellularization.

Authors: Jiwangga, Dhihintia¹ (AUTHOR), Mahyudin, Ferdiansyah^2,3 (AUTHOR) ferdiansyah@fk.unair.ac.id, Mastutik, Gondo⁴ (AUTHOR), Lazuwardi, Rasya Azka⁵ (AUTHOR)

Source: Artificial Organs. Apr2025, Vol. 49 Issue 4, p627-638. 12p.

Subject Terms: *DNA, *GLYCOSAMINOGLYCANS, *EXTRACELLULAR matrix, *IMMUNE response, *TENSILE strength, *STRENGTH of materials, *AGGREGATION (Statistics)

Intra-articular injection of ascorbic acid enhances microfracture-mediated cartilage repair.

Authors: Chen, Zhian¹ (AUTHOR), Zhang, Sihe² (AUTHOR), Duan, Peiya³ (AUTHOR), Yin, Zhengbo¹ (AUTHOR), Dong, Shuangbin¹ (AUTHOR), Pang, Rongqing⁴ (AUTHOR) pangrq2000@aliyun.com, Tan, Hongbo⁵ (AUTHOR) doccza@163.com

Source: Scientific Reports. 2/28/2024, Vol. 14 Issue 1, p1-12. 12p.

Subject Terms: *GLYCOSAMINOGLYCANS, *INTRA-articular injections, *CARTILAGE, *VITAMIN C, *REVERSE transcriptase polymerase chain reaction, *MESENCHYMAL stem cells

An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans.

Authors: Matoušková, Zuzana^1,2 (AUTHOR) zuzana.matouskova@uochb.cas.cz, Orsághová, Katarína^1,3 (AUTHOR) katarina.orsaghova@uochb.cas.cz, Srb, Pavel¹ (AUTHOR) michal.busa@uochb.cas.cz, Pytelková, Jana¹ (AUTHOR) milan.fabry@uochb.cas.cz, Kukačka, Zdeněk⁴ (AUTHOR), Buša, Michal¹ (AUTHOR) martin.horn@uochb.cas.cz, Hajdušek, Ondřej⁵ (AUTHOR), Šíma, Radek^5,6 (AUTHOR), Fábry, Milan¹ (AUTHOR), Novák, Petr⁴ (AUTHOR), Horn, Martin¹ (AUTHOR), Kopáček, Petr⁵ (AUTHOR), Mareš, Michael¹ (AUTHOR) michael.mares@uochb.cas.cz

Source: International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 4, p2240. 21p.

Subject Terms: *CATHEPSINS, *GLYCOSAMINOGLYCANS, *PROTEOLYSIS, *LYME disease, *TICK-borne encephalitis, *CASTOR bean tick

Antioxidant and antiproliferative effect of a glycosaminoglycan extract from Rapana venosa marine snail.

Authors: Gaspar-Pintiliescu, Alexandra¹ (AUTHOR), Stefan, Laura M.¹ (AUTHOR) laura.stefan@incdsb.ro, Mihai, Elena¹ (AUTHOR), Sanda, Catalina¹ (AUTHOR), Manoiu, Vasile S.¹ (AUTHOR), Berger, Daniela² (AUTHOR), Craciunescu, Oana¹ (AUTHOR)

Source: PLoS ONE. 2/15/2024, Vol. 19 Issue 2, p1-16. 16p.

Subject Terms: *GLYCOSAMINOGLYCANS, *CHONDROITIN sulfates, *HUMAN cell culture, *HEPARAN sulfate, *INHIBITION of cellular proliferation, *IRON ions

Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin.

Authors: Yang, Jiyuan^1,2 (AUTHOR) songy11@rpi.edu, Song, Yuefan² (AUTHOR) xiak@rpi.edu, Jin, Weihua³ (AUTHOR) jinweihua@zjut.edu.cn, Xia, Ke² (AUTHOR) wangc5@rpi.edu, Burnett, Grace C.⁴ (AUTHOR) gburnett@umc.edu, Qiao, Wanjin¹ (AUTHOR) wanjin.qiao@mssm.edu, Bates, John T.⁴ (AUTHOR) jtbates@umc.edu, Pomin, Vitor H.⁵ (AUTHOR) vpomin@olemiss.edu, Wang, Chunyu² (AUTHOR) linhar@rpi.edu, Qiao, Mingqiang¹ (AUTHOR) qiaomq@nankai.edu.cn, Linhardt, Robert J.^2,6 (AUTHOR), Dordick, Jonathan S.⁶ (AUTHOR) dordick@rpi.edu, Zhang, Fuming⁶ (AUTHOR) dordick@rpi.edu

Source: Viruses (1999-4915). Feb2024, Vol. 16 Issue 2, p237. 15p.

Subject Terms: *GLYCOSAMINOGLYCANS, *CHONDROITIN sulfate proteoglycan, *MERS coronavirus, *GLYCANS, *CHONDROITIN sulfates, *HEPARAN sulfate proteoglycans, *HEPARIN, *SURFACE plasmon resonance

Geographic Terms: MIDDLE East

Hyaluronan: Sources, Structure, Features and Applications.

Authors: Valachová, Katarína¹ (AUTHOR) katarina.valachova@savba.sk, Hassan, Mohamed E.^1,2 (AUTHOR), Šoltés, Ladislav¹ (AUTHOR)

Source: Molecules. Feb2024, Vol. 29 Issue 3, p739. 15p.

Subject Terms: *HYALURONIC acid, *GLYCOSAMINOGLYCANS, *MEDICAL polymers, *NANOMEDICINE, *MOLAR mass, *ORGANS (Anatomy), *MEDICAL practice

The Lifespan of D. melanogaster Depends on the Function of the Gagr Gene, a Domesticated gag Gene of Drosophila LTR Retrotransposons.

Authors: Balakireva, Yevgenia¹ (AUTHOR) balakireva.evgesha@mail.ru, Nikitina, Maria¹ (AUTHOR) masha-nn23@yandex.ru, Makhnovskii, Pavel² (AUTHOR) maxpauel@gmail.com, Kukushkina, Inna¹ (AUTHOR) vladimirova-bph@yandex.ru, Kuzmin, Ilya¹ (AUTHOR) kuzmin.ilya@gmail.com, Kim, Alexander^1,3 (AUTHOR) aikim57@mail.ru, Nefedova, Lidia¹ (AUTHOR) nefedova@mail.bio.msu.ru

Source: Insects (2075-4450). Jan2024, Vol. 15 Issue 1, p68. 20p.

Subject Terms: *RETROTRANSPOSONS, *GLYCOSAMINOGLYCANS, *GENE expression, *GENETIC models, *DROSOPHILA, *FLY control

Structure and functional impact of glycosaminoglycan modification of HSulf-2 endosulfatase revealed by atomic force microscopy and mass spectrometry.

Authors: Seffouh, Ilham¹ (AUTHOR), Bilong, Mélanie¹ (AUTHOR), Przybylski, Cédric¹ (AUTHOR), El Omrani, Nesrine¹ (AUTHOR), Poyer, Salomé¹ (AUTHOR), Lamour, Guillaume¹ (AUTHOR), Clément, Marie-Jeanne² (AUTHOR), Boustany, Rebecca-Joe³ (AUTHOR), Gout, Evelyne³ (AUTHOR), Gonnet, Florence¹ (AUTHOR), Vivès, Romain R.³ (AUTHOR), Daniel, Régis¹ (AUTHOR) regis.daniel@univ-evry.fr

Source: Scientific Reports. 12/14/2023, Vol. 13 Issue 1, p1-14. 14p.

Subject Terms: *ATOMIC force microscopy, *GLYCOSAMINOGLYCANS, *MASS spectrometry, *HEPARAN sulfate proteoglycans, *POST-translational modification, *DERMATAN sulfate

Investigation of Glycosaminoglycans in Urine and Their Alteration in Patients with Juvenile Idiopathic Arthritis.

Authors: Lato-Kariakin, Elżbieta¹ (AUTHOR) elalato@op.pl, Kuźnik-Trocha, Kornelia¹ (AUTHOR) kkuznik@sum.edu.pl, Gruenpeter, Anna² (AUTHOR) anna.gruenpeter@gmail.com, Komosińska-Vassev, Katarzyna¹ (AUTHOR) kvassev@sum.edu.pl, Olczyk, Krystyna¹ (AUTHOR) olczyk@sum.edu.pl, Winsz-Szczotka, Katarzyna¹ (AUTHOR) winsz@sum.edu.pl

Source: Biomolecules (2218-273X). Dec2023, Vol. 13 Issue 12, p1737. 14p.

Subject Terms: *JUVENILE idiopathic arthritis, *GLYCOSAMINOGLYCANS, *HEPARAN sulfate, *BIOTHERAPY, *HYALURONIC acid, *ECTOPIC pregnancy, *CONNECTIVE tissues, *URINE

Carrageenan-amino acid interaction as a tool for understanding atherosclerotic process initiation.

Authors: de Picoli, Paula Monique Chiconi¹, Soares, Tatiane Araújo¹, Gonçalves, Adriano Marques², Trovatti, Eliane¹

Source: Electronic Journal of General Medicine; Jun2024, Vol. 21 Issue 3, p1-9, 9p

In Situ Deposition of Drug and Gene Nanoparticles on a Patterned Supramolecular Hydrogel to Construct a Directionally Osteochondral Plug.

Authors: Kang, Jiawei¹ (AUTHOR), Li, Yaping^2,3 (AUTHOR), Qin, Yating^2,3 (AUTHOR), Huang, Zhongming⁴ (AUTHOR), Wu, Yifan¹ (AUTHOR), Sun, Long⁵ (AUTHOR), Wang, Cong¹ (AUTHOR), Wang, Wei^2,3 (AUTHOR) wwgfz@zju.edu.cn, Feng, Gang¹ (AUTHOR) gangfeng@zju.edu.cn, Qi, Yiying¹ (AUTHOR) qiyiying@zju.edu.cn

Source: Nano-Micro Letters. 11/17/2023, Vol. 16 Issue 1, p1-19. 19p.

Subject Terms: *GLYCOSAMINOGLYCANS, *MESENCHYMAL stem cell differentiation, *CARTILAGE regeneration, *HYDROGELS, *BONE regeneration, *REACTIVE oxygen species, *NANOPARTICLES

Assessing Genetic Algorithm-Based Docking Protocols for Prediction of Heparin Oligosaccharide Binding Geometries onto Proteins.

Authors: Holmes, Samuel G.^1,2 (AUTHOR) holmess@vcu.edu, Desai, Umesh R.^1,2 (AUTHOR) urdesai@vcu.edu

Source: Biomolecules (2218-273X). Nov2023, Vol. 13 Issue 11, p1633. 20p.

Subject Terms: *GLYCOSAMINOGLYCANS, *HEPARIN, *HEPARAN sulfate, *MOLECULAR docking, *OLIGOSACCHARIDES, *HIGH throughput screening (Drug development), *CARRIER proteins, *PROTEINS