Biochemical characterization of the human ubiquitous glucose‐6‐phosphatase in neutrophil granulocytes

Authors: Zsigmond Lédeczi, Klaudia Németh, Tamás Kardon

Source: FEBS Open Bio, Vol 15, Iss 2, Pp 285-295 (2025)

Subject Terms: endoplasmic reticulum, enzyme kinetics, glucose‐6‐phosphatase catalytic subunit 3, glucose‐6‐phosphate transporter, neutrophil granulocytes, substrate specificity, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2211-5463

Access URL: https://doaj.org/article/4e11f6dc7bbb42b0988dd6857ce496d6

Case report of congenital neutropenia type 4 with glucose‐6‐phosphatase catalytic subunit 3 (G6PC3) deficiency.

Authors: Dhayhi, Nabil S.¹ (AUTHOR), Mahnashi, Mohammed A.² (AUTHOR), Mokhasha, Alanoud I.³ (AUTHOR), Ahmed, Lana F.³ (AUTHOR), Shamakhi, Ahmed E.⁴ (AUTHOR), Ageel, Adeeb A.⁵ (AUTHOR), Tohary, Mohammed A.⁵ (AUTHOR), Alhazmi, Abdulaziz H.⁶ (AUTHOR) abalhazmi@jazanu.edu.sa

Source: Clinical Case Reports. Feb2024, Vol. 12 Issue 2, p1-4. 4p.

Subject Terms: *GLUCOSE-6-phosphatase, *NEUTROPENIA, *GENETIC disorders, *PUERPERIUM, *DISEASE relapse, *PRESSURE ulcers

Geographic Terms: QIZAN (Saudi Arabia : Province), SAUDI Arabia

Drosophila neuronal Glucose-6-Phosphatase is a modulator of neuropeptide release that regulates muscle glycogen stores via FMRFamide signaling.

Authors: Tetsuya Miyamoto¹, Sheida Hedjazi¹, Chika Miyamoto¹, Amrein, Hubert¹, amrein@tamu.edu

Source: Proceedings of the National Academy of Sciences of the United States of America; 7/23/2024, Vol. 121 Issue 30, p1-10, 10p

The Current Status and Advance in Treatment of Glycogen Storage Disease Type Ⅰb

Authors: JIANG Jingjing, MA Mingsheng

Source: 罕见病研究, Vol 3, Iss 4, Pp 522-526 (2024)

Subject Terms: glycogen storage disease type ⅰb, glucose-6-phosphatase, mechanism, treatment, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2097-0501

Access URL: https://doaj.org/article/89aeb0e0954242c49c97cd8f2e5d0d62

The role of glucose-6-phosphatase activity in glucose homeostasis and its potential for diabetes therapy

Authors: Tan, Lay Shuen ^{1, 2}, Lau, Hwee Hui ¹, Abdelalim, Essam M. ^{3, 4}, Khoo, Chin Meng ^{5, 6}, O’Brien, Richard M. ⁷, Tai, E. Shyong ^{5, 6}, Teo, Adrian Kee Keong ^{1, 5, 6, 8, ⁎}

Source: In Trends in Molecular Medicine February 2025 31(2):152-164

Absence of hexose‐6‐phosphate dehydrogenase results in reduced overall glucose consumption but does not prevent 11β‐hydroxysteroid dehydrogenase‐1‐dependent glucocorticoid activation.

Authors: Marbet, Philippe¹, Klusonova, Petra¹, Birk, Julia¹, Kratschmar, Denise V.¹, Odermatt, Alex¹ alex.odermatt@unibas.ch

Source: FEBS Journal. Nov2018, Vol. 285 Issue 21, p3993-4004. 12p.

Subject Terms: *GLUCOSE-6-phosphatase, *HYDROXYSTEROID dehydrogenases, *GLUCOSE in the body, *GLUCOCORTICOID regulation, *DEHYDROGENATION

Chlorogenic Acid, a Potential Glucose-6-Phosphatase Inhibitor: An Approach to Develop a Pre-Clinical Glycogen Storage Disease Type I Model.

Authors: Patil, Santosh B.¹, Gadad, Pramod C.¹, gadadpramod@gmail.com

Source: Indian Journal of Pharmaceutical Education & Research; 2024 Supplement, Vol. 58, pS372-S381, 10p

Gold nanoparticles partition to and increase the activity of glucose-6-phosphatase in a synthetic phospholipid membrane system.

Authors: MacCormack, Tyson J.¹ tmaccormack@mta.ca, Rundle, Amanda M.¹, Malek, Michael¹, Raveendran, Abhilash¹, Meli, Maria-Victoria¹ vmeli@mta.ca

Source: PLoS ONE. 8/17/2017, Vol. 12 Issue 8, p1-15. 15p.

Subject Terms: *GLUCOSE-6-phosphatase, *GOLD nanoparticles, *PHOSPHOLIPIDS, *BILAYER lipid membranes, *MEMBRANE proteins, *LIGANDS (Biochemistry)

Meta-analyses of the association of G6PC2 allele variants with elevated fasting glucose and type 2 diabetes.

Authors: Shi, Yuanyuan¹, Li, Yuqian², Wang, Jinjin³, Wang, Chongjian¹, Fan, Jingjing¹, Zhao, Jingzhi⁴, Yin, Lei⁴, Liu, Xuejiao¹, Zhang, Dongdong¹, Li, Linlin¹ lilinlin@zzu.edu.cn

Source: PLoS ONE. 7/13/2017, Vol. 12 Issue 7, p1-20. 20p.

Subject Terms: *GENETICS of type 2 diabetes, *GLUCOSE-6-phosphatase, *FASTING, *ETHNICITY, *META-analysis

Downregulation of SIRT1 signaling underlies hepatic autophagy impairment in glycogen storage disease type Ia.

Authors: Cho, Jun-Ho¹ chouja@mail.nih.gov, Kim, Goo-Young¹, Pan, Chi-Jiunn¹, Anduaga, Javier¹, Choi, Eui-Ju², Mansfield, Brian C.^1,3, Chou, Janice Y.¹

Source: PLoS Genetics. 5/30/2017, Vol. 13 Issue 5, p1-20. 20p.

Subject Terms: *GLUCOSE-6-phosphatase, *GLYCOGEN storage disease, *SIRTUINS, *GLUCOSE metabolism, *IMMUNOPRECIPITATION

Using G6PD tests to enable the safe treatment of Plasmodium vivax infections with primaquine on the Thailand-Myanmar border: A cost-effectiveness analysis.

Authors: Devine, Angela^1,2, Lubell, Yoel^1,2, Chu, Cindy S.^2,3, Bancone, Germana^2,3, Nosten, François^2,3, Price, Ric N.^2,4, Parmiter, Minnie⁵, Yeung, Shunmay⁶

Source: PLoS Neglected Tropical Diseases. 5/24/2017, Vol. 11 Issue 5, p1-19. 19p.

Subject Terms: *PLASMODIUM vivax, *GLUCOSE-6-phosphatase, *HEMOLYSIS & hemolysins, *PRIMAQUINE, *DIAGNOSIS, *THERAPEUTICS

Evolutionary history of glucose-6-phosphatase encoding genes in vertebrate lineages: towards a better understanding of the functions of multiple duplicates.

Authors: Marandel, Lucie¹ lucie.marandel@inra.fr, Panserat, Stéphane¹, Plagnes-Juan, Elisabeth¹, Arbenoits, Eva¹, Soengas, José Luis², Bobe, Julien³

Source: BMC Genomics. 5/2/2017, Vol. 18, p1-13. 13p. 3 Diagrams, 2 Graphs.

Subject Terms: *BIOLOGICAL evolution, *GLUCOSE-6-phosphatase, *GENES, *VERTEBRATE evolution, *CHROMOSOME duplication

Identification of Hypoglycemic Glycolipids from Ipomoea murucoides by Affinity-Directed Fractionation, In Vitro, In Silico and Dynamic Light Scattering Analysis.

Authors: Rosas-Ramírez, Daniel, Arreguín-Espinosa, Roberto, Escandón-Rivera, Sonia, Andrade-Cetto, Adolfo, Mata-Torres, Gerardo, Pérez-Solís, Ricardo

Source: Plants (2223-7747); Mar2024, Vol. 13 Issue 5, p644, 12p

Subject Terms: GLYCOLIPIDS, LIGHT scattering, LIVER enzymes, IPOMOEA, GLUCOSIDASES, NUCLEAR magnetic resonance, GLUCOSE-6-phosphatase

Glucose-6-Phosphate Dehydrogenase Deficiency and Physical and Mental Health until Adolescence.

Authors: Kwok, Man Ki¹, Leung, Gabriel M.¹, Schooling, C. Mary^1,2 cms1@hku.hk

Source: PLoS ONE. 11/8/2016, Vol. 11 Issue 11, p1-14. 14p.

Subject Terms: *MENTAL health of teenagers, *GLUCOSE-6-phosphatase, *DEHYDROGENASES, *GENERALIZED estimating equations, *BLOOD pressure, *BODY mass index

Biophysical and functional properties of purified glucose-6-phosphatase catalytic subunit 1.

Authors: Claxton, Derek P.¹ derek.p.claxton@vanderbilt.edu, Overway, Emily M.¹, Oeser, James K.¹, O'Brien, Richard M.¹, Mchaourab, Hassane S.¹

Source: Journal of Biological Chemistry. Jan2022, Vol. 298 Issue 1, p1-13. 13p.

Subject Terms: *GLUCOSE-6-phosphatase, *GLYCOGEN storage disease, *CARRIER proteins, *BLOOD sugar, *CHEMICAL fingerprinting, *GLUCOSE-6-phosphate dehydrogenase

Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells.

Authors: Das, Mahua R.¹, Bag, Arup K.², Saha, Shekhar¹, Ghosh, Alok³, Dey, Sumit K.¹, Das, Provas¹, Mandal, Chitra², Ray, Subhankar⁴, Chakrabarti, Saikat⁵, Ray, Manju⁶ manjuray@mail.jcbose.ac.in, Jana, Siddhartha S.¹ bcssj@iacs.res.in

Source: BMC Cancer. 2/24/2016, Vol. 16, p1-12. 12p. 1 Diagram, 6 Graphs.

Subject Terms: *GLUCOSE-6-phosphatase, *PYRUVATE kinase, *GLYCERALDEHYDEPHOSPHATE dehydrogenase, *CANCER cells, *MOLECULAR docking, *GLYCOLYSIS, *IMMUNOPRECIPITATION, *MASS spectrometry

Genome editing using Staphylococcus aureus Cas9 in a canine model of glycogen storage disease Ia

Authors: Benjamin Arnson, Hye Ri Kang, Elizabeth D. Brooks, Dorothy Gheorghiu, Ekaterina Ilich, David Courtney, Jeffrey I. Everitt, Bryan R. Cullen, Dwight D. Koeberl

Source: Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 108-119 (2023)

Subject Terms: genome editing, CRISPR-Cas9, adeno-associated virus vectors, inherited disorder of metabolism, glycogen storage disease, glucose-6-phosphatase, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050123000372; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/8282e120c0924cec897cf976a2665255

Three novel mutations of the G6PC gene identified in Chinese patients with glycogen storage disease type Ia.

Authors: Zheng, Bi-Xia¹ zbx_88117@163.com, Lin, Qian¹ j_jnc@163.com, Li, Mei¹ limei6389@yahoo.com.cn, Jin, Yu² jinyuldyy@163.com

Source: European Journal of Pediatrics. Jan2015, Vol. 174 Issue 1, p59-63. 5p. 3 Charts, 1 Graph.

Subject Terms: *GLYCOGEN storage disease, *GLUCOSE-6-phosphatase, *GLYCOGEN storage disease type I, *GENETIC mutation, *GENETIC code, *POLYMERASE chain reaction, *GENETICS, HEALTH of Chinese people

A molecular signature for the G6PC3/SLC37A2/SLC37A4 interactors in glioblastoma disease progression and in the acquisition of a brain cancer stem cell phenotype

Authors: Sima Torabidastgerdooei, Marie-Eve Roy, Borhane Annabi

Source: Frontiers in Endocrinology, Vol 14 (2023)

Subject Terms: glioblastoma, glucose-6-phosphatase system, G6PC3, G6PT, SLC37A2, SLC37A4, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2023.1265698/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/43150942dd5a440d9c1811bcd81cd9ce

Anti-citrullinated glucose-6-phosphate isomerase peptide antibodies in patients with rheumatoid arthritis are associated with HLA- DRB1 shared epitope alleles and disease activity.

Authors: Umeda, N.¹, Matsumoto, I.¹, Ito, I.², Kawasaki, A.², Tanaka, Y.¹, Inoue, A.¹, Tsuboi, H.¹, Suzuki, T.¹, Hayashi, T.¹, Ito, S.¹, Tsuchiya, N.², Sumida, T.¹

Source: Clinical & Experimental Immunology. Apr2013, Vol. 172 Issue 1, p44-53. 10p. 1 Black and White Photograph, 1 Chart, 4 Graphs.

Subject Terms: *GLUCOSE-6-phosphatase, *ISOMERASES, *PEPTIDES, *IMMUNOGLOBULINS, *RHEUMATOID arthritis, *ALLELES, *AUTOANTIBODIES