Oxidative and nitrosative stress in bipolar affective disorder and its familial aggregation.

Authors: Singh, Harpreet¹, Singh, Abhishek K.², Kar, Sujita K.¹, Tripathi, Adarsh¹, Dalal, Pronob K.¹, Dikshit, Madhu² drmadhudikshit@gmail.com

Source: Indian Journal of Psychiatry. Feb2025, Vol. 67 Issue 2, p209-218. 10p.

Subject Terms: *GENETICS of bipolar disorder, *BIPOLAR disorder, *RESEARCH funding, *NEUTROPHILS, *OXIDATIVE stress, *DESCRIPTIVE statistics, *HYDROCORTISONE, *REACTIVE nitrogen species, *REACTIVE oxygen species, *OXIDOREDUCTASES, *NITRIC acid

Neurocognition and affective temperament in first-degree relatives of patients with bipolar disorder in south India: a cross-sectional study.

Authors: Lakshmanamoorthy, Thenmozhi¹ dr.then16@gmail.com, Rajendran, Bharathi², Shanmugavinayagam, Arumuganathan¹, Appadurai, Praveena Daya³, Raja, Ayyakutti Muni⁴, Kathiah, Rajeswari⁵

Source: East Asian Archives of Psychiatry. Dec2024, Vol. 34 Issue 4, p122-127. 6p.

Subject Terms: *FAMILIES & psychology, *GENETICS of bipolar disorder, *CROSS-sectional method, *COGNITIVE testing, *TEMPERAMENT, *STATISTICAL significance, *EXECUTIVE function, *TERTIARY care, *CHI-squared test, *MANN Whitney U Test, *DESCRIPTIVE statistics, *AFFECT (Psychology), *SHORT-term memory, *DATA analysis software, *PHENOTYPES

Geographic Terms: INDIA

Aberrant brain network topology in youth with a familial risk for bipolar disorder: a task‐based fMRI connectome study.

Authors: Pan, Nanfang^1,2,3, Qin, Kun^2,3, Patino, Luis R.³, Tallman, Maxwell J.³, Lei, Du⁴, Lu, Lu^1,3, Li, Wenbin¹, Blom, Thomas J.³, Bruns, Kaitlyn M.³, Welge, Jeffrey A.³, Strawn, Jeffrey R.³, Gong, Qiyong^1,5 qiyonggong@hmrrc.org.cn, Sweeney, John A.^1,3, Singh, Manpreet K.⁶, DelBello, Melissa P.³

Source: Journal of Child Psychology & Psychiatry. Aug2024, Vol. 65 Issue 8, p1072-1086. 15p.

Subject Terms: *GENETICS of bipolar disorder, *BIPOLAR disorder, *RESEARCH funding, *BRAIN, *MAGNETIC resonance imaging, *DESCRIPTIVE statistics, *MACHINE learning, *COMPARATIVE studies, *BRAIN mapping, *BIOMARKERS, *DISEASE risk factors, *ADOLESCENCE

Different brain functional network abnormalities between attention-deficit/hyperactivity disorder youth with and without familial risk for bipolar disorder.

Authors: Qin, Kun^1,2,3, Lei, Du⁴ alien18@163.com, Zhu, Ziyu^1,2, Li, Wenbin⁵, Tallman, Maxwell J.², Rodrigo Patino, L.², Fleck, David E.², Aghera, Veronica², Gong, Qiyong¹ qiyonggong@hmrrc.org.cn, Sweeney, John A.^1,2, McNamara, Robert K.², DelBello, Melissa P.²

Source: European Child & Adolescent Psychiatry. May2024, Vol. 33 Issue 5, p1395-1405. 11p.

Subject Terms: *GENETICS of bipolar disorder, *BIPOLAR disorder, *STATISTICAL correlation, *FUNCTIONAL connectivity, *ATTENTION-deficit hyperactivity disorder, *RESEARCH funding, *BRAIN, *MAGNETIC resonance imaging, *FAMILY history (Medicine), *LARGE-scale brain networks, *RESEARCH, *COMPARATIVE studies, *DISEASE susceptibility, *DISEASE risk factors, *ADOLESCENCE

Geographic Terms: CHINA

Attachment representations in 7‐year‐old children at familial high risk of schizophrenia or bipolar disorder: Associations with mental disorders and daily functioning: The Danish High Risk and Resilience Study, VIA 7‐A population‐based cohort study

Authors: Gregersen, Maja^1,2 maja.gregersen@regionh.dk, Ellersgaard, Ditte¹, Søndergaard, Anne^1,2, Christiani, Camilla^1,2, Hemager, Nicoline^1,2,3, Spang, Katrine Søborg³, Burton, Birgitte Klee^3,4,5, Uddin, Md Jamal^1,2, Ohland, Jessica^1,2, Gantriis, Ditte^2,6, Greve, Aja^2,6, Hjorthøj, Carsten^1,2,7, Mors, Ole^2,6,8, Plessen, Kerstin Jessica⁹, Nordentoft, Merete^1,2,4, Clemmensen, Lars¹, Jepsen, Jens Richardt Møllegaard^1,2,3,10, Thorup, Anne Amalie Elgaard^2,3,4

Source: Scandinavian Journal of Psychology. Dec2023, Vol. 64 Issue 6, p776-783. 8p.

Subject Terms: *RISK factors of schizophrenia in children, *GENETICS of bipolar disorder, *MENTAL illness risk factors, *SCHIZOPHRENIA in children, *PSYCHOSOCIAL functioning, *CASE-control method, *ATTACHMENT behavior, *RISK assessment, *COMPARATIVE studies, *RESEARCH funding, *DESCRIPTIVE statistics, *BIPOLAR disorder, *LONGITUDINAL method, *DISEASE risk factors, *CHILDREN

Geographic Terms: DENMARK

Downregulated Mitochondrial DNA Encoded Iong Noncoding Rnas in Individuals with Bipolar Disorder and Their Siblings.

Alternate Title: Bipolar Bozukluğu Olan Bireyler ve Kardeşlerinde Mitokondri Kökenli Uzun Kodlamayan RNA İfadeleri.

Authors: Aksahin, Izel Cemre¹, Arat-Çelik, Hidayet Ece², Fettahoğlu, İbrahim¹, Kendirlioğlu, Burcu Kök², Kaymakçı, Esma Çörekli², Ceylan, Deniz³

Source: Archives of Neuropsychiatry / Nöropsikiyatri Arşivi. 2024 Supplement, Vol. 61, p16-17. 2p.

Subject Terms: *GENETICS of bipolar disorder, *CONFERENCES & conventions, *RNA, *GENE expression, *MITOCHONDRIAL DNA

Geographic Terms: TURKEY

Uncovering novel drug targets for bipolar disorder: a Mendelian randomization analysis of brain, cerebrospinal fluid, and plasma proteomes.

Source: Psychological Medicine. Aug2024, Vol. 54 Issue 11, p1-11. 11p.

Subject Terms: *BRAIN physiology, *GENETICS of bipolar disorder, *BIPOLAR disorder, *RISK assessment, *GENOME-wide association studies, *MOLECULAR epidemiology, *RESEARCH funding, *CARRIER proteins, *GENES, *GENETIC polymorphisms, *PROTEOMICS, *BLOOD plasma, *CEREBROSPINAL fluid, *GENETICS, *PHENOTYPES, *DISEASE risk factors

Larger putamen in individuals at risk and with manifest bipolar disorder.

Source: Psychological Medicine. Aug2024, Vol. 54 Issue 11, p1-11. 11p.

Subject Terms: *GENETICS of bipolar disorder, *BIPOLAR disorder, *RISK assessment, *RESEARCH funding, *BRAIN, *OCCIPITAL lobe, *BASAL ganglia, *MAGNETIC resonance imaging, *CLASSIFICATION of mental disorders, *FAMILY history (Medicine), *GRAY matter (Nerve tissue), *PARIETAL lobe, *BIOMARKERS, *DISEASE risk factors

Childhood trauma in children at familial high risk of schizophrenia or bipolar disorder: A longitudinal study. The Danish High Risk and Resilience Study – VIA 7 and VIA 11.

Authors: Brandt, Julie Marie^1,2,3 julie.marie.brandt@regionh.dk, Hemager, Nicoline^1,2,3, Gregersen, Maja^1,2,3, Søndergaard, Anne^1,2,3, Krantz, Mette Falkenberg^1,2, Ohland, Jessica^1,2, Wilms, Martin^1,2, Rohd, Sinnika Birkehøj^1,2, Hjorthøj, Carsten^1,2,4, Veddum, Lotte^2,5,6, Knudsen, Christina Bruun^2,5,6, Andreassen, Anna Krogh^2,5,6, Greve, Aja^2,6, Spang, Katrine Søborg^1,2, Christiani, Camilla Austa⁷, Ellersgaard, Ditte^1,2, Burton, Birgitte Klee^2,7, Gantriis, Ditte Lou^2,5,6, Bliksted, Vibeke^5,6, Mors, Ole^2,5,6

Source: British Journal of Clinical Psychology. Nov2022, Vol. 61 Issue 4, p875-894. 20p.

Subject Terms: *RISK factors of schizophrenia in children, *GENETICS of bipolar disorder, *PREVENTION of injury, *SCHIZOPHRENIA in children, *CONFIDENCE intervals, *SOCIAL support, *RESEARCH methodology, *ONE-way analysis of variance, *INTERVIEWING, *EMOTIONAL trauma, *POST-traumatic stress disorder, *RISK assessment, *RESEARCH funding, *ODDS ratio, *LOGISTIC regression analysis, *WOUNDS & injuries, *BIPOLAR disorder, *DISEASE risk factors, *CHILDREN

Mental disorders in preadolescent children at familial high‐risk of schizophrenia or bipolar disorder – a four‐year follow‐up study: The Danish High Risk and Resilience Study, VIA 11.

Authors: Gregersen, Maja^1,2,3 maja.gregersen@regionh.dk, Søndergaard, Anne^1,2,3, Brandt, Julie Marie^1,2,3, Ellersgaard, Ditte¹, Rohd, Sinnika Birkehøj^1,2, Hjorthøj, Carsten^1,2,4, Ohland, Jessica^1,2, Krantz, Mette Falkenberg^1,2,3, Wilms, Martin^1,2, Andreassen, Anna Krogh^2,5,6, Knudsen, Christina Bruun^2,5,6, Veddum, Lotte^2,5,6, Greve, Aja^2,6, Bliksted, Vibeke^5,6, Mors, Ole^2,5,6, Clemmensen, Lars⁷, Møllegaard Jepsen, Jens Richardt^1,2,7,8, Nordentoft, Merete^1,2,3, Hemager, Nicoline^1,2,3, Thorup, Anne Amalie Elgaard^2,3,7

Source: Journal of Child Psychology & Psychiatry. Sep2022, Vol. 63 Issue 9, p1046-1056. 11p. 2 Charts, 3 Graphs.

Subject Terms: *GENETICS of schizophrenia, *GENETICS of bipolar disorder, *PSYCHIATRIC epidemiology, *CONFIDENCE intervals, *PSYCHOLOGICAL vulnerability, *AGE distribution, *RISK assessment, *CHILD psychiatry, *ADOLESCENT psychiatry, *BEHAVIOR disorders, *ATTENTION-deficit hyperactivity disorder, *DESCRIPTIVE statistics, *AFFECTIVE disorders, *PATHOLOGICAL psychology, *ODDS ratio, *ANXIETY disorders, *PSYCHOLOGICAL stress, *ADJUSTMENT disorders, *CHILDREN

Heterogeneity of social cognitive and language functions in children at familial high-risk of severe mental illness; The Danish High Risk and Resilience Study VIA 7.

Authors: Christiani, Camilla Jerlang^1,2 camilla.austa.christiani@regionh.dk, Hemager, Nicoline^1,2,3, Ellersgaard, Ditte^1,2, Thorup, Anne A. E.^1,2, Spang, Katrine Søborg^2,3, Burton, Birgitte Klee^2,3, Gregersen, Maja^1,2, Søndergaard, Anne^1,2, Greve, Aja^2,4, Gantriis, Ditte Lou^2,4, Mors, Ole^2,4, Plessen, Kerstin J.^2,3,5, Nordentoft, Merete^1,2,6, Jepsen, Jens Richardt Møllegaard^1,2,3,7

Source: European Child & Adolescent Psychiatry. Jun2022, Vol. 31 Issue 6, p991-1002. 12p. 1 Illustration, 3 Charts, 1 Graph.

Subject Terms: *GENETICS of schizophrenia, *GENETICS of bipolar disorder, *MENTAL illness risk factors, *MENTAL illness genetics, *THOUGHT & thinking, *SOCIAL perception, *IDENTIFICATION, *CLASSIFICATION, *LANGUAGE & languages, *PATIENTS, *RISK assessment, *SEVERITY of illness index, *CLUSTER analysis (Statistics), *SOCIAL responsibility, *CHILDREN

Mental illness and cardiovascular health: observational and polygenic score analyses in a population-based cohort study.

Authors: Veeneman, R. R.¹ r.r.veeneman@amsterdamumc.nl, Vermeulen, J. M.², Bialas, M.¹, Bhamidipati, A. K.¹, Abdellaoui, A.¹, Munafò, M. R.^3,4, Denys, D.², Bezzina, C. R.⁵, Verweij, K. J. H.¹, Tadros, R.⁶, Treur, J. L.¹

Source: Psychological Medicine. Apr2024, Vol. 54 Issue 5, p931-939. 9p.

Subject Terms: *HYPERTENSION risk factors, *GENETICS of bipolar disorder, *MENTAL depression genetics, *GENETICS of schizophrenia, *ATHEROSCLEROSIS risk factors, *RISK assessment, *SELF-evaluation, *STATISTICAL models, *RESEARCH funding, *CARDIOVASCULAR diseases risk factors, *DESCRIPTIVE statistics, *GENETIC risk score, *LONGITUDINAL method, *ARRHYTHMIA, *HEART beat, *ODDS ratio, *BLOOD pressure, *CONFIDENCE intervals, *DISEASE risk factors

GENOMICS FOR THE PEOPLE.

Authors: Strauss, Kevin A.

Source: Scientific American. Dec2015, Vol. 313 Issue 6, p66-73. 8p.

Subjects: GENETIC disorders, GENETIC disorders in children, GENETIC testing, MENNONITES, AMISH, GENETICS of bipolar disorder, DIAGNOSIS, HEALTH, GENETIC disorder treatment, PREVENTION

State- and trait-related dysfunctions in bipolar disorder across different mood states: a graph theory study.

Authors: Chen, Yifan¹, Zhao, Pengfei¹, Pan, Chunyu¹, Chang, Miao¹, Zhang, Xizhe¹, Duan, Jia¹, Wei, Yange¹, Tang, Yanqing¹ fei.wang@cmu.edu.cn, Wang, Fei¹ fei.wang@yale.edu

Source: Journal of Psychiatry & Neuroscience. 2024, Vol. 49 Issue 1, pE11-E22. 12p.

Subject Terms: *BRAIN physiology, *GENETICS of bipolar disorder, *COGNITION disorders, *AFFECT (Psychology), *NEURAL pathways, *MAGNETIC resonance imaging, *RISK assessment, *WHITE matter (Nerve tissue), *COMPARATIVE studies, *MENTAL depression, *RESEARCH funding, *ANXIETY, *BIPOLAR disorder, *SECONDARY analysis, *DISEASE risk factors

Brain structural trajectories in youth at familial risk for schizophrenia or bipolar disorder according to development of psychosis spectrum symptoms.

Authors: Sugranyes, Gisela^1,2,3 gernest@clinic.cat, Serna, Elena³, Ilzarbe, Daniel^2,4, Pariente, Jose Carlos¹, Borras, Roger¹, Romero, Soledad^1,2,3, Rosa, Mireia¹, Baeza, Inmaculada^1,2,3,4, Moreno, Maria Dolores^3,5, Bernardo, Miguel^1,3,4,6, Vieta, Eduard^1,3,4,6, Castro‐Fornieles, Josefina^1,2,3,4

Source: Journal of Child Psychology & Psychiatry. Jun2021, Vol. 62 Issue 6, p780-789. 10p. 1 Chart, 2 Graphs.

Subject Terms: *RISK factors of schizophrenia in children, *GENETICS of bipolar disorder, *BRAIN, *SCHIZOPHRENIA in children, *PSYCHOSES, *MAGNETIC resonance imaging, *MEDICAL screening, *RISK assessment, *PRE-tests & post-tests, *DESCRIPTIVE statistics, *BIPOLAR disorder, *LONGITUDINAL method, *DISEASE risk factors, *CHILDREN, *ADOLESCENCE

GLENN CLOSE: My Family's Mental Health Journey. (cover story)

Authors: McNEIL, LIZ (AUTHOR)

Source: People. 5/24/2021, Vol. 95 Issue 21, p54-57. 4p. 7 Color Photographs, 1 Black and White Photograph.

Subjects: CLOSE, Glenn, 1947-, CELEBRITY family relationships, MENTAL illness, BIPOLAR disorder, SCHIZOAFFECTIVE disorders, GENETICS of bipolar disorder, GENETICS of schizophrenia, HINSHAW, Stephen

Familial aggregation analysis of cognitive performance in early-onset bipolar disorder.

Authors: Soler, Jordi^1,2,3, Lera-Miguel, Sara^4,5, Lázaro, Luisa^3,4,5,6, Calvo, Rosa^3,4,5, Ferentinos, Panagiotis⁷, Fañanás, Lourdes^1,2,3, Fatjó-Vilas, Mar^1,2,3,8 mfatjo-vilas@fidmag.com

Source: European Child & Adolescent Psychiatry. Dec2020, Vol. 29 Issue 12, p1705-1716. 12p. 1 Diagram, 1 Chart.

Subject Terms: *GENETICS of bipolar disorder, *ATTENTION, *COGNITIVE testing, *FAMILY health, *MEMORY, *EXECUTIVE function, *DATA analysis software, *DESCRIPTIVE statistics

Preliminary results from the Australian Genetics of Bipolar Disorder Study: A nation-wide cohort.

Authors: Lind, Penelope A^1,2,3 (AUTHOR) penelope.lind@qimrberghofer.edu.au, Siskind, Dan J^3,4 (AUTHOR), Hickie, Ian B⁵ (AUTHOR), Colodro-Conde, Lucía¹ (AUTHOR), Cross, Simone¹ (AUTHOR), Parker, Richard¹ (AUTHOR), Martin, Nicholas G⁶ (AUTHOR), Medland, Sarah E^1,3,7 (AUTHOR)

Source: Australian & New Zealand Journal of Psychiatry. Nov2023, Vol. 57 Issue 11, p1428-1442. 15p.

Subject Terms: *GENETICS of bipolar disorder, *SALIVA analysis, *AGE distribution, *MEDICAL care costs, *GENETIC testing, *SEVERITY of illness index, *COMPARATIVE studies, *SEX distribution, *DESCRIPTIVE statistics, *QUESTIONNAIRES, *RESEARCH funding, *DRUG side effects, *PHYSICIAN practice patterns, *DATA analysis software, *BIPOLAR disorder, *LONGITUDINAL method, *MEDICARE, *ADULTS

Geographic Terms: AUSTRALIA

Case Report: Association of Comorbid Psychiatric Disorders and Sigmoid Prolapse with de novo POGZ Mutation.

Authors: Wright, Cary M.¹, Guter, Stephen J.¹, Cook, Edwin H.¹, edcook@uic.edu

Source: Journal of Autism & Developmental Disorders; Mar2022, Vol. 52 Issue 3, p1408-1411, 4p, 1 Chart

Unraveling NEK4 as a Potential Drug Target in Schizophrenia and Bipolar I Disorder: A Proteomic and Genomic Approach.

Authors: Zhang, Chengcheng, Yang, ZhiHui, Li, Xiaojing, Zhao, Liansheng, Guo, Wanjun, Deng, Wei, Wang, Qiang, Hu, Xun, Li, Ming, Sham, Pak Chung, Xiao, Xiao, Li, Tao

Source: Schizophrenia Bulletin; Sep2024, Vol. 50 Issue 5, p1185-1196, 12p

Subject Terms: DRUG therapy for schizophrenia, SCHIZOPHRENIA risk factors, GENETICS of bipolar disorder, GENETICS of schizophrenia, BIPOLAR disorder, GENOMICS, RESEARCH funding, NEURONS, SCHIZOPHRENIA, DESCRIPTIVE statistics, MESSENGER RNA, GENE expression, MICE, PROTEOMICS, NEUROPEPTIDES, GENE expression profiling, ANIMAL experimentation, DISEASE risk factors