Sex-specific biphasic alpha-synuclein response and alterations of interneurons in a COVID-19 hamster modelResearch in context

Authors: Cara Sophie Schreiber, Ivo Wiesweg, Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Mounogou Kouassi, Berfin Schaumburg, Gülsah Gabriel, Franziska Richter, Christopher Käufer

Source: EBioMedicine, Vol 105, Iss , Pp 105191- (2024)

Subject Terms: Neurodegenerative disease, Neuroinflammation, Neurological symptoms, Post COVID-19 condition, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396424002263; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/e45e6ae0ee064fa4ba818cc757df359c

Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection

Authors: Swantje Thiele, Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Mounogou Kouassi, Martin Zickler, Martin Müller, Berfin Tuku, Patricia Resa-Infante, Debby van Riel, Malik Alawi, Thomas Günther, Franziska Rother, Stefanie Hügel, Susanne Reimering, Alice McHardy, Adam Grundhoff, Wolfram Brune, Albert Osterhaus, Michael Bader, Enno Hartmann, Gülsah Gabriel

Source: Cell Reports, Vol 43, Iss 4, Pp 114023- (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124724003516; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/ae73ceb0ca434ca7aaaeca856302775f

Hamster model for post-COVID-19 alveolar regeneration offers an opportunity to understand post-acute sequelae of SARS-CoV-2

Authors: Laura Heydemann, Małgorzata Ciurkiewicz, Georg Beythien, Kathrin Becker, Klaus Schughart, Stephanie Stanelle-Bertram, Berfin Schaumburg, Nancy Mounogou-Kouassi, Sebastian Beck, Martin Zickler, Mark Kühnel, Gülsah Gabriel, Andreas Beineke, Wolfgang Baumgärtner, Federico Armando

Source: Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/53b9c1576d8c44418feec4ae624b8f8b

H7N9 avian influenza virus infection in men is associated with testosterone depletion

Authors: Tian Bai, Yongkun Chen, Sebastian Beck, Stephanie Stanelle-Bertram, Nancy Kouassi Mounogou, Tao Chen, Jie Dong, Bettina Schneider, Tingting Jia, Jing Yang, Lijie Wang, Andreas Meinhardt, Antonia Zapf, Lothar Kreienbrock, Dayan Wang, Yuelong Shu, Gülsah Gabriel

Source: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/90639160fbfc45449f78fce58ed1c760

Impaired Degradation of Neutrophil Extracellular Traps: A Possible Severity Factor of Elderly Male COVID-19 Patients

Authors: Nicole de Buhr, Ann Christin Parplys, Maria Schroeder, Timo Henneck, Berfin Schaumburg, Stephanie Stanelle-Bertram, Dominik Jarczak, Axel Nierhaus, Jens Hiller, Sven Peine, Stefan Kluge, Karin Klingel, Gülsah Gabriel, Maren von Köckritz-Blickwede

Source: Journal of Innate Immunity, Pp 1-16 (2022)

Subject Terms: neutrophil extracellular traps, covid-19, elderly male, ll-37, Medicine, Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/521594; https://doaj.org/toc/1662-811X; https://doaj.org/toc/1662-8128

Access URL: https://doaj.org/article/99fc27d9aa3342cca629fa7cd36b581a

Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life

Authors: Henning Jacobsen, Kerstin Walendy-Gnirß, Nilgün Tekin-Bubenheim, Nancy Mounogou Kouassi, Isabel Ben-Batalla, Nikolaus Berenbrok, Martin Wolff, Vinicius Pinho dos Reis, Martin Zickler, Lucas Scholl, Annette Gries, Hanna Jania, Andreas Kloetgen, Arne Düsedau, Gundula Pilnitz-Stolze, Aicha Jeridi, Ali Önder Yildirim, Helmut Fuchs, Valerie Gailus-Durner, Claudia Stoeger, Martin Hrabe de Angelis, Tatjana Manuylova, Karin Klingel, Fiona J. Culley, Jochen Behrends, Sonja Loges, Bianca Schneider, Susanne Krauss-Etschmann, Peter Openshaw, Gülsah Gabriel

Source: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e3a6daa33a83457bb051d8afd208dbb6

Assessing and improving the validity of COVID-19 autopsy studies - A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses

Authors: Susanne Krasemann, Carsten Dittmayer, Saskia von Stillfried, Jenny Meinhardt, Fabian Heinrich, Kristin Hartmann, Susanne Pfefferle, Edda Thies, Regina von Manitius, Tom Alex David Aschman, Josefine Radke, Anja Osterloh, Simone Schmid, Eva Miriam Buhl, Jana Ihlow, Frank Dubois, Viktor Arnhold, Sefer Elezkurtaj, David Horst, Andreas Hocke, Sara Timm, Sebastian Bachmann, Victor Corman, Hans-Hilmar Goebel, Jakob Matschke, Stephanie Stanelle-Bertram, Gülsah Gabriel, Danielle Seilhean, Homa Adle-Biassette, Benjamin Ondruschka, Matthias Ochs, Werner Stenzel, Frank L. Heppner, Peter Boor, Helena Radbruch, Michael Laue, Markus Glatzel

Source: EBioMedicine, Vol 83, Iss , Pp 104193- (2022)

Subject Terms: SARS-CoV-2, COVID-19, Autopsy, Immunohistochemistry, Electron microscopy, Pathology, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396422003747; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/8c3f588c9dc544439b18fd7f7d5e9f6b

Microgliosis and neuronal proteinopathy in brain persist beyond viral clearance in SARS-CoV-2 hamster model

Authors: Christopher Käufer, Cara S. Schreiber, Anna-Sophia Hartke, Ivo Denden, Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Mounogou Kouassi, Georg Beythien, Kathrin Becker, Tom Schreiner, Berfin Schaumburg, Andreas Beineke, Wolfgang Baumgärtner, Gülsah Gabriel, Franziska Richter

Source: EBioMedicine, Vol 79, Iss , Pp 103999- (2022)

Subject Terms: Alpha-synuclein, Tau, Neuroinfection, Neurodegenerative disease, Animal model, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396422001839; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/7fa0aba7ec2946cc8e68ddea03a9558e

T-705-Derived Prodrugs Show High Antiviral Efficacies against a Broad Range of Influenza A Viruses with Synergistic Effects When Combined with Oseltamivir

Authors: Benedikt Ganter, Martin Zickler, Johanna Huchting, Matthias Winkler, Anna Lüttjohann, Chris Meier, Gülsah Gabriel, Sebastian Beck

Source: Pharmaceutics, Vol 15, Iss 6, p 1732 (2023)

Subject Terms: influenza A virus, antiviral drug, Favipiravir, T-705, T-1105, T-1106, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/6/1732; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/46a02f57c8784cd38d672ff065905e19

Pre-existing helminth infection impairs the efficacy of adjuvanted influenza vaccination in mice.

Authors: Wiebke Hartmann, Marie-Luise Brunn, Nadine Stetter, Gülsah Gabriel, Minka Breloer

Source: PLoS ONE, Vol 17, Iss 3, p e0266456 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a6796fae088240d29363374a54ecf60a

In Vitro Investigation of the Interaction of Avian Metapneumovirus and Newcastle Disease Virus with Turkey Respiratory and Reproductive Tissue

Authors: Frederik Bexter, Nancy Rüger, Hicham Sid, Alexandra Herbst, Gülsah Gabriel, Albert Osterhaus, Silke Rautenschlein

Source: Viruses, Vol 15, Iss 4, p 907 (2023)

Subject Terms: oviduct organ culture (OOC), tracheal organ culture (TOC), avian metapneumovirus, newcastle disease virus, virus–host interactions, importin-alpha, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/15/4/907; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/50234728c49f49c5906e6cd6ea1e73c4

A Combination of Deworming and Prime-Boost Vaccination Regimen Restores Efficacy of Vaccination Against Influenza in Helminth-Infected Mice

Authors: Nadine Stetter, Wiebke Hartmann, Marie-Luise Brunn, Stephanie Stanelle-Bertram, Gülsah Gabriel, Minka Breloer

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: anthelmintic treatment, flubendazole, immunomodulation, influenza, Litomosoides sigmodontis, parasite infection, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.784141/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ba2e5fa5e31d4be7a2d99b0402c31a51

Inefficient Placental Virus Replication and Absence of Neonatal Cell-Specific Immunity Upon Sars-CoV-2 Infection During Pregnancy

Authors: Ann-Christin Tallarek, Christopher Urbschat, Luis Fonseca Brito, Stephanie Stanelle-Bertram, Susanne Krasemann, Giada Frascaroli, Kristin Thiele, Agnes Wieczorek, Nadine Felber, Marc Lütgehetmann, Udo R. Markert, Kurt Hecher, Wolfram Brune, Felix Stahl, Gülsah Gabriel, Anke Diemert, Petra Clara Arck

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: prenatal infection, vertical transfer, variants of concern, SARS-CoV, T cell response, human trial, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.698578/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/97c2554c8b154c33b749bebc61c60812

Vasculitis and Neutrophil Extracellular Traps in Lungs of Golden Syrian Hamsters With SARS-CoV-2

Authors: Kathrin Becker, Georg Beythien, Nicole de Buhr, Stephanie Stanelle-Bertram, Berfin Tuku, Nancy Mounogou Kouassi, Sebastian Beck, Martin Zickler, Lisa Allnoch, Gülsah Gabriel, Maren von Köckritz-Blickwede, Wolfgang Baumgärtner

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: vasculitis, neutrophils extracellular traps (NETs), SARS-CoV-2, hamster, COVID-19, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.640842/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3f41d3fe931446e6bb730cea2ce2842d

Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication

Authors: Gustavo Garcia, Jr., Arun Sharma, Arunachalam Ramaiah, Chandani Sen, Arunima Purkayastha, Donald B. Kohn, Mark S. Parcells, Sebastian Beck, Heeyoung Kim, Malina A. Bakowski, Melanie G. Kirkpatrick, Laura Riva, Karen C. Wolff, Brandon Han, Constance Yuen, David Ulmert, Prabhat K. Purbey, Phillip Scumpia, Nathan Beutler, Thomas F. Rogers, Arnab K. Chatterjee, Gülsah Gabriel, Ralf Bartenschlager, Brigitte Gomperts, Clive N. Svendsen, Ulrich A.K. Betz, Robert D. Damoiseaux, Vaithilingaraja Arumugaswami

Source: Cell Reports, Vol 35, Iss 1, Pp 108940- (2021)

Subject Terms: COVID-19, SARS-CoV-2, high-throughput screen, protein kinase inhibitors, nucleoside analogs, mTOR-PI3K-AKT pathway, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124721002540; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/0ec6b74831ff49ac9031607cb9aa9694

Mutations in the H7 HA and PB1 genes of avian influenza a viruses increase viral pathogenicity and contact transmission in guinea pigs

Authors: Carola Dreier, Patricia Resa-Infante, Swantje Thiele, Stephanie Stanelle-Bertram, Kerstin Walendy-Gnirß, Thomas Speiseder, Annette Preuss, Zacharias Müller, Hans-Dieter Klenk, Jürgen Stech, Gülsah Gabriel

Source: Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1324-1336 (2019)

Subject Terms: H7 avian influenza A viruses, HA and PB1 gene mutations, pathogenicity, transmission, guinea pigs, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/47c976aa43974b7dafc82487e9295a8b

Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection

Authors: Swantje Thiele, Stephanie Stanelle-Bertram, Sebastian Beck, Nancy Mounogou Kouassi, Martin Zickler, Martin Müller, Berfin Tuku, Patricia Resa-Infante, Debby van Riel, Malik Alawi, Thomas Günther, Franziska Rother, Stefanie Hügel, Susanne Reimering, Alice McHardy, Adam Grundhoff, Wolfram Brune, Albert Osterhaus, Michael Bader, Enno Hartmann, Gülsah Gabriel

Source: Cell Reports, Vol 31, Iss 3, Pp - (2020)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720304599; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/edfd0389405d4980bc3513e20871ef7e

Testosterone Protects Against Severe Influenza by Reducing the Pro-Inflammatory Cytokine Response in the Murine Lung

Authors: Berfin Tuku, Stephanie Stanelle-Bertram, Julie Sellau, Sebastian Beck, Tian Bai, Nancy Mounogou Kouassi, Annette Preuß, Stefan Hoenow, Thomas Renné, Hanna Lotter, Gülsah Gabriel

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: influenza A virus, sex differences, testosterone, 2009 H1N1, androgens, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.00697/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/0ba9b0f1ab874631ae1687d1d60c73da

Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method

Authors: Dan Dou, Iván Hernández-Neuta, Hao Wang, Henrik Östbye, Xiaoyan Qian, Swantje Thiele, Patricia Resa-Infante, Nancy Mounogou Kouassi, Vicky Sender, Karina Hentrich, Peter Mellroth, Birgitta Henriques-Normark, Gülsah Gabriel, Mats Nilsson, Robert Daniels

Source: Cell Reports, Vol 20, Iss 1, Pp 251-263 (2017)

Subject Terms: RNA viruses, viral genome labeling and localization, influenza A virus, RNA labeling, vRNAs, IAV entry, IAV cell co-infections, IAV replication cycle, single-cell IAV genome trafficking, single-nucleotide specificity, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717308185; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/2ee362c616d947dfbed1f3838ee56203

Helminth Infections Suppress the Efficacy of Vaccination against Seasonal Influenza

Authors: Wiebke Hartmann, Marie-Luise Brunn, Nadine Stetter, Nicola Gagliani, Franziska Muscate, Stephanie Stanelle-Bertram, Gülsah Gabriel, Minka Breloer

Source: Cell Reports, Vol 29, Iss 8, Pp 2243-2256.e4 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719313658; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/6d41aff946264f798fe526a4d6eafe27