Cardiac and metabolic safety profile of antipsychotics in youths: A WHO safety database analysis

Authors: Merino, Diane, Gérard, Alexandre O., Destere, Alexandre, Saidessalam, Haitam, Askenazy, Florence, Montastruc, François, Drici, Milou-Daniel, Thümmler, Susanne

Source: In Psychiatry Research April 2024 334

Drug-induced cardiac toxicity and adverse drug reactions, a narrative review

Authors: Destere, Alexandre, Merino, Diane, Lavrut, Thibaud, Rocher, Fanny, Viard, Delphine, Drici, Milou-Daniel, Gérard, Alexandre O.

Source: In Therapies March-April 2024 79(2):161-172

Optimization of Rituximab Therapy in Adult Patients With PLA2R1-Associated Membranous Nephropathy With Artificial Intelligence

Authors: Destere, Alexandre, Teisseyre, Maxime, Merino, Diane, Cremoni, Marion, Gérard, Alexandre O, Crepin, Thomas, Jourde-Chiche, Noémie, Graça, Daisy, Zorzi, Kévin, Fernandez, Céline, Brglez, Vesna, Benzaken, Sylvia, Esnault, Vincent L.M., Benito, Sylvain, Drici, Milou-Daniel, Seitz-Polski, Barbara

Source: In Kidney International Reports January 2024 9(1):134-144

Drug-related catatonia in youths: real-world insights from the WHO Safety Database.

Authors: Merino, Diane^1,2, Gérard, Alexandre O.², Lavrut, Thibaud², Askenazy, Florence^3,4, Thümmler, Susanne^3,4, Montastruc, François⁵, Drici, Milou-Daniel² pharmacovigilance@chu-nice.fr

Source: European Child & Adolescent Psychiatry. May2024, Vol. 33 Issue 5, p1383-1393. 11p.

Subject Terms: *PHARMACOLOGY, *ONDANSETRON, *PATIENT safety, *CYCLOSPORINE, *OLANZAPINE, *CHILD psychiatry, *DESCRIPTIVE statistics, *HALOPERIDOL, *ODDS ratio, *CHLORPROMAZINE, *BENZTROPINE, *CATATONIA, *CONFIDENCE intervals, *VACCINES, *ADOLESCENCE, *CHILDREN

Company/Entity: WORLD Health Organization

The Neuropsychiatric Safety Profile of Lasmiditan: A Comparative Disproportionality Analysis with Triptans

Authors: Merino, Diane, Gérard, Alexandre O., Van Obberghen, Elise K., Destere, Alexandre, Lanteri-Minet, Michel, Drici, Milou-Daniel

Source: In Neurotherapeutics September 2023 20(5):1305-1315

A HPLC-DAD method to facilitate large-scale therapeutic drug monitoring of dalbavancin

Authors: Destere, Alexandre, Merino, Diane, Bonesso, Laurent, Lavrut, Thibaud, Bernasconni, Anaïs, Garraffo, Rodolphe, Gérard, Alexandre O., Drici, Milou-Daniel

Source: In Journal of Chromatography B 1 May 2023 1222

Association Between Maintenance Immunosuppressive Regimens and COVID-19 Mortality in Kidney Transplant Recipients

Authors: Gérard, Alexandre O., Barbosa, Susana, Anglicheau, Dany, Couzi, Lionel, Hazzan, Marc, Thaunat, Olivier, Blancho, Gilles, Caillard, Sophie, Sicard, Antoine

Source: Transplantation. 106(10):2063-2067

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179324911.0x000001&indx=1&recIds=ETOCvdc_100179324911.0x000001

Drug-Induced Tubulointerstitial Nephritis: Insights From the World Health Organization Safety Database

Authors: Gérard, Alexandre O., Merino, Diane, Laurain, Audrey, Cremoni, Marion, Andreani, Marine, Rocher, Fanny, Destere, Alexandre, Esnault, Vincent L.M., Sicard, Antoine, Drici, Milou-Daniel

Source: Kidney international reports. 7(7):1699-1702

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167220275.0x000001&indx=1&recIds=ETOCvdc_100167220275.0x000001

PDL1 inhibitors may be associated with a lower risk of allograft rejection than PD1 and CTLA4 inhibitors: analysis of the WHO pharmacovigilance database.

Authors: Gérard, Alexandre O., Merino, Diane, Benzaquen, Jonathan, Destere, Alexandre, Borchiellini, Delphine, Gosset, Clément, Rocher, Fanny, Andreani, Marine, Marquette, Charles-Hugo, Montaudié, Henri, Drici, Milou-Daniel, Sicard, Antoine

Source: Frontiers in Immunology; 2025, p1-6, 6p

Subject Terms: DRUG side effects, IMMUNE checkpoint inhibitors, GRAFT rejection, FACIAL transplantation, DATABASES

Remdesivir and Acute Renal Failure: A Potential Safety Signal From Disproportionality Analysis of the WHO Safety Database

Authors: Gérard, Alexandre O., Laurain, Audrey, Fresse, Audrey, Parassol, Nadège, Muzzone, Marine, Rocher, Fanny, Esnault, Vincent L.M., Drici, Milou‐Daniel

Source: Clinical pharmacology & therapeutics. 109(4):1021-1024

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117506545.0x000001&indx=1&recIds=ETOCvdc_100117506545.0x000001

New Strategies for Volume Control in Patients with Diabetes Mellitus, a Narrative Review.

Authors: Gérard, Alexandre O.^1,2 (AUTHOR) gerard.a@chu-nice.fr, Laurain, Audrey¹ (AUTHOR) laurain.a@chu-nice.fr, Sicard, Antoine¹ (AUTHOR) sicard.a@chu-nice.fr, Merino, Diane² (AUTHOR) pharmacovigilance@chu-nice.fr, Pathak, Atul³ (AUTHOR) atul.pathak@chpg.mc, Drici, Milou-Daniel² (AUTHOR), Favre, Guillaume¹ (AUTHOR) favre.g@chu-nice.fr, Esnault, Vincent L. M.¹ (AUTHOR) esnault.v@chu-nice.fr

Source: Pharmaceutics. Aug2022, Vol. 14 Issue 8, p1569-1569. 15p.

Subject Terms: *SODIUM-glucose cotransporters, *DIABETES, *PEOPLE with diabetes, *RENIN-angiotensin system, *KIDNEY tubules, *MINERALOCORTICOID receptors, *CHRONIC kidney failure

An artificial intelligence algorithm for co‐clustering to help in pharmacovigilance before and during the COVID‐19 pandemic.

Authors: Destere, Alexandre, Marchello, Giulia, Merino, Diane, Othman, Nouha Ben, Gérard, Alexandre O., Lavrut, Thibaud, Viard, Delphine, Rocher, Fanny, Corneli, Marco, Bouveyron, Charles, Drici, Milou‐Daniel

Source: British Journal of Clinical Pharmacology; May2024, Vol. 90 Issue 5, p1258-1267, 10p

Subject Terms: COVID-19 pandemic, ARTIFICIAL intelligence, DRUG side effects, DRUG monitoring, MEDICATION safety

Real‐World Data on the Risk of Ventricular Arrhythmias with Sulfonamides

Authors: Gérard, Alexandre O., Merino, Diane, Drici, Milou‐Daniel

Source: Clinical pharmacology & therapeutics. 112(2):201-202

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192967639.0x000001&indx=1&recIds=ETOCvdc_100192967639.0x000001

CAR-T Cells and the Kidney: Insights from the WHO Safety Database.

Authors: Gérard, Alexandre O.^1,2,3 (AUTHOR), Merino, Diane² (AUTHOR), Charbinat, Alexis³ (AUTHOR), Fournier, Joseph¹ (AUTHOR), Destere, Alexandre² (AUTHOR), Loschi, Michael⁴ (AUTHOR), Cluzeau, Thomas⁴ (AUTHOR), Sicard, Antoine^1,3,5 (AUTHOR), Drici, Milou-Daniel² (AUTHOR) pharmacovigilance@chu-nice.fr

Source: BioDrugs. Jul2023, Vol. 37 Issue 4, p521-530. 10p.

Subject Terms: *ACUTE kidney failure, *CYTOKINE release syndrome, *DATABASES, *DRUG side effects, *CHIMERIC antigen receptors

Risk factors associated with immune checkpoint inhibitor–induced acute kidney injury compared with other immune-related adverse events: a case–control study.

Authors: Gérard, Alexandre O^1,2 (AUTHOR), Barbosa, Susana³ (AUTHOR), Parassol, Nadège² (AUTHOR), Andreani, Marine¹ (AUTHOR), Merino, Diane² (AUTHOR), Cremoni, Marion¹ (AUTHOR), Laurain, Audrey¹ (AUTHOR), Pinel, Sylvine⁴ (AUTHOR), Bourneau-Martin, Delphine⁵ (AUTHOR), Rocher, Fanny² (AUTHOR), Esnault, Vincent L M¹ (AUTHOR), Borchiellini, Delphine⁶ (AUTHOR), Sicard, Antoine^1,7,8 (AUTHOR), Drici, Milou-Daniel² (AUTHOR) pharmacovigilance@chu-nice.fr, Centers, French Network of Pharmacovigilance (AUTHOR)

Source: Clinical Kidney Journal. Oct2022, Vol. 15 Issue 10, p1881-1887. 7p.

Subject Terms: *DRUG side effects, *ACUTE kidney failure, *IMMUNE checkpoint proteins, *IMMUNE checkpoint inhibitors, *CASE-control method, *LUPUS nephritis, *KIDNEY diseases

Medications as a Trigger of Sleep-Related Eating Disorder: A Disproportionality Analysis.

Authors: Merino, Diane^1,2 (AUTHOR) gerard.a@chu-nice.fr, Gérard, Alexandre O.^2,3 (AUTHOR) ben-othman.n@chu-nice.fr, Van Obberghen, Elise K.⁴ (AUTHOR) vanobberghen-blanc.e@chu-nice.fr, Ben Othman, Nouha² (AUTHOR) viard.d@chu-nice.fr, Ettore, Eric¹ (AUTHOR) ettore.e@chu-nice.fr, Giordana, Bruno¹ (AUTHOR) giordana.b@chu-nice.fr, Viard, Delphine² (AUTHOR) rocher.f@chu-nice.fr, Rocher, Fanny² (AUTHOR) destere.a@chu-nice.fr, Destere, Alexandre² (AUTHOR), Benoit, Michel¹ (AUTHOR) benoit.m@chu-nice.fr, Drici, Milou-Daniel² (AUTHOR) pharmacovigilance@chu-nice.fr

Source: Journal of Clinical Medicine. Jul2022, Vol. 11 Issue 13, p3890-N.PAG. 10p.

Subject Terms: *GAMMA-hydroxybutyrate, *DRUG side effects, *PSYCHIATRIC drugs, *EATING disorders, *DRUGS

Adverse Drug Reactions of Olanzapine, Clozapine and Loxapine in Children and Youth: A Systematic Pharmacogenetic Review.

Authors: Merino, Diane, Fernandez, Arnaud, Gérard, Alexandre O., Ben Othman, Nouha, Rocher, Fanny, Askenazy, Florence, Verstuyft, Céline, Drici, Milou-Daniel, Thümmler, Susanne

Source: Pharmaceuticals (14248247); Jun2022, Vol. 15 Issue 6, p749-N.PAG, 27p

Subject Terms: DRUG side effects, CLOZAPINE, ANTIPSYCHOTIC agents, GENETIC polymorphisms, CYTOCHROMES, ARIPIPRAZOLE, OLANZAPINE

COVID-19 Vaccine-Associated Transient Global Amnesia: A Disproportionality Analysis of the WHO Safety Database.

Authors: Merino, Diane, Gérard, Alexandre O., Van Obberghen, Elise K., Ben Othman, Nouha, Ettore, Eric, Giordana, Bruno, Viard, Delphine, Rocher, Fanny, Destere, Alexandre, Benoit, Michel, Drici, Milou-Daniel

Source: Frontiers in Pharmacology; 5/20/2022, Vol. 13, p1-6, 6p

Subject Terms: COVID-19, AMNESIA, DRUG side effects, COVID-19 vaccines

Company/Entity: WORLD Health Organization

Calcitonin gene-related peptide-targeting drugs and Raynaud's phenomenon: a real-world potential safety signal from the WHO pharmacovigilance database.

Authors: Gérard, Alexandre O.^1,2,3, Merino, Diane¹, Van Obberghen, Elise K.⁴, Rocher, Fanny¹, Destere, Alexandre¹, Lantéri-Minet, Michel^4,5, Drici, Milou-Daniel¹ pharmacovigilance@chu-nice.fr

Source: Journal of Headache & Pain. 5/3/2022, Vol. 23 Issue 1, p1-7. 7p.

Subject Terms: *THERAPEUTIC use of monoclonal antibodies, *RAYNAUD'S disease, *DATABASES, *TRYPTAMINE, *MEDICAL information storage & retrieval systems, *CONFIDENCE intervals, *MIGRAINE, *NEUROPEPTIDES, *PHARMACOLOGY, *CALCITONIN, *ADRENERGIC beta blockers, *DRUG side effects, *PATIENT safety, *CHEMICAL inhibitors

Company/Entity: WORLD Health Organization

Immune checkpoint inhibitors-induced nephropathy: a French national survey.

Authors: Gérard, Alexandre O.^1,2 (AUTHOR), Andreani, Marine¹ (AUTHOR), Fresse, Audrey² (AUTHOR), Parassol, Nadège² (AUTHOR), Muzzone, Marine³ (AUTHOR), Pinel, Sylvine⁴ (AUTHOR), Bourneau-Martin, Delphine⁵ (AUTHOR), Borchiellini, Delphine⁶ (AUTHOR), Rocher, Fanny² (AUTHOR), Esnault, Vincent L. M.¹ (AUTHOR), Drici, Milou-Daniel² (AUTHOR) pharmacovigilance@chu-nice.fr

Source: Cancer Immunology, Immunotherapy. Nov2021, Vol. 70 Issue 11, p3357-3364. 8p.

Subject Terms: *IMMUNE checkpoint proteins, *ACUTE kidney failure, *KIDNEY diseases, *DRUG side effects, *IMMUNE checkpoint inhibitors