Inflammatory Stimulation Upregulates the Receptor Transporter Protein 4 (RTP4) in SIM-A9 Microglial Cells.

Authors: Fujita, Wakako^1,2 (AUTHOR) w.fujita.ss@juntendo.ac.jp, Kuroiwa, Yusuke³ (AUTHOR)

Source: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 24, p13676. 14p.

Subject Terms: *G protein coupled receptors, *CARRIER proteins, *MOLECULAR chaperones, *MITOGEN-activated protein kinases, *INTERFERON receptors

Regulation of Cannabinoid and Opioid Receptor Levels by Endogenous and Pharmacological Chaperones

Authors: Gupta, Achla, Gomes, Ivone, Osman, Aya, Fujita, Wakako ¹, Devi, Lakshmi A. ^*

Source: In The Journal of Pharmacology and Experimental Therapeutics November 2024 391(2):279-288

The impact of elevated blood lead levels in children on maternal health-related quality of life

Authors: Nakata, Hokuto, Tohyama, Harukazu, Fujita, Wakako, Nakayama, Shouta M.M., Ishizuka, Mayumi, Yabe, John, Munyinda, Nosiku S., Sakala, Doreen, Choongo, Kennedy, Yamasaki, Shojiro, Nagai, Natsumi, Yoshida, Takahiko, Saito, Takeshi

Source: In Chemosphere September 2021 279

Activation of µ-δ opioid receptor heteromers inhibits neuropathic pain behavior in rodents

Authors: Tiwari, Vinod, He, Shao-Qiu, Huang, Qian, Liang, Lingli, Yang, Fei, Chen, Zhiyong, Tiwari, Vineeta, Fujita, Wakako, Devi, Lakshmi A., Dong, Xinzhong, Guan, Yun, Raja, Srinivasa N.

Source: Pain. 161(4):842-855

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180426123.0x000001&indx=1&recIds=ETOCvdc_100180426123.0x000001

Aiming at Ideal Therapeutics-MOPr/DOPr or MOPr-DOPr Heteromertargeting Ligand

Authors: Fujita, Wakako

Source: Current topics in medicinal chemistry. 20(31):2843-2851

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112760160.0x000001&indx=1&recIds=ETOCvdc_100112760160.0x000001

Regulation of an Opioid Receptor Chaperone Protein, RTP4, by Morphine

Authors: Fujita, Wakako ^*, Yokote, Mini, Gomes, Ivone, Gupta, Achla, Ueda, Hiroshi, Devi, Lakshmi A. ^*

Source: In Molecular Pharmacology January 2019 95(1):11-19

Receptor Transporter Protein 4 (RTP4) in the Hypothalamus Is Involved in the Development of Antinociceptive Tolerance to Morphine.

Authors: Fujita, Wakako¹ (AUTHOR) wakakofu@nagasaki-u.ac.jp, Uchida, Hitoshi^2,3 (AUTHOR), Kawanishi, Masashi⁴ (AUTHOR), Kuroiwa, Yusuke⁴ (AUTHOR), Abe, Manabu^2,5 (AUTHOR), Sakimura, Kenji^2,5 (AUTHOR)

Source: Biomolecules (2218-273X). Oct2022, Vol. 12 Issue 10, pN.PAG-N.PAG. 13p.

Subject Terms: *CARRIER proteins, *PROTEIN receptors, *OPIOID receptors, *MOLECULAR chaperones, *DRUG traffic, *TOLL-like receptors, *HYPOTHALAMUS

Two delta opioid receptor subtypes are functional in single ventral tegmental area neurons, and can interact with the mu opioid receptor

Authors: Margolis, Elyssa B., Fujita, Wakako, Devi, Lakshmi A., Fields, Howard L.

Source: In Neuropharmacology 1 September 2017 123:420-432

Tanzanian women’s coping and understanding of labour: A qualitative study at the Amtulabhai Antenatal Clinic

Authors: Fujita, Wakako, Leshabari, Sebalda, Mlay, Ecstasy Danford, Ohashi, Kazutomo

Source: In International Journal of Africa Nursing Sciences 2017 7:4-10

Quality of partogram monitoring at a primary health centre in Zambia

Authors: Fujita, Wakako, Mukumbuta, Lubinda, Chavuma, Roy, Ohashi, Kazutomo

Source: In Midwifery January 2015 31(1):191-196

Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers

Authors: Fujita, Wakako, Gomes, Ivone, Dove, Leonard S., Prohaska, David, McIntyre, Gail, Devi, Lakshmi A.

Source: In Biochemical Pharmacology 1 December 2014 92(3):448-456

G Protein—Coupled Receptor Heteromers

Authors: Gomes, Ivone, Ayoub, Mohammed Akli, Fujita, Wakako, Jaeger, Werner C., Pfleger, Kevin D. G., Devi, Lakshmi A.

Source: Annual review of pharmacology and toxicology. 56:403-426

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN608324505&indx=1&recIds=ETOCRN608324505

Identification of a µ-δ opioid receptor heteromer-biased agonist with antinociceptive activity

Authors: Gomes, Ivone, Fujita, Wakako, Gupta, Achla, Saldanha, Adrian S., Negri, Ana, Pinello, Christine E., Roberts, Edward, Filizola, Marta, Hodder, Peter, Devi, Lakshmi A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Jul . 110(29), 12072-12077.

Access URL: https://www.jstor.org/stable/42712528

Disease-Specific Heteromerization of G-Protein-Coupled Receptors That Target Drugs of Abuse

Authors: Gomes, Lvone, Fujita, Wakako, Chandrakala, Moraje V, Devi, Lakshmi A

Source: Progress in Molecular Biology and Translational Science. 2013, v. 117, p207-265.

Endogenous oxytocin levels in extracted saliva elevates during breastfeeding correlated with lower postpartum anxiety in primiparous mothers.

Authors: Nagahashi-Araki, Miyuki, Tasaka, Makoto, Takamura, Tsunehiko, Eto, Hiromi, Sasaki, Noriko, Fujita, Wakako, Miyazaki, Asuka, Morifuji, Kanako, Honda, Naoko, Miyamura, Tunetake, Nishitani, Shota

Source: BMC Pregnancy & Childbirth; 9/17/2022, Vol. 22 Issue 1, p1-10, 10p

Heteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities.

Authors: Fujita, Wakako¹, Gomes, Ivone¹, Devi, Lakshmi A¹

Source: British Journal of Pharmacology. Jan2015, Vol. 172 Issue 2, p375-387. 13p.

Subject Terms: *OPIOID receptors, *PHARMACOLOGY, *CELLULAR signal transduction, *G protein coupled receptors, *LIGANDS (Biochemistry), *PHARMACEUTICAL research

Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR Review 10.

Authors: Fujita, Wakako¹, Gomes, Ivone¹, Devi, Lakshmi A¹

Source: British Journal of Pharmacology. Sep2014, Vol. 171 Issue 18, p4155-4176. 22p. 4 Charts.

Subject Terms: *G protein coupled receptors, *CELLULAR signal transduction, *OPIOID receptors, *PROTEIN binding, *LIGANDS (Biochemistry), *MORPHINE

Μ opioid receptor activity is regulated by endothelin converting enzyme‐2 (659.5)

Authors: Bobeck, Erin, Gupta, Achla, Fujita, Wakako, Gomes, Ivone, Devi, Lakshmi

Source: FASEB journal. 28

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100146378706.0x000001&indx=1&recIds=ETOCvdc_100146378706.0x000001

Neuroprotective DAMPs member prothymosin alpha has additional beneficial actions against cerebral ischemia-induced vascular damages

Authors: Maeda, Shiori, Sasaki, Keita, Halder, Sebok Kumar, Fujita, Wakako, Ueda, Hiroshi

Source: In Journal of Pharmacological Sciences September 2016 132(1):100-104

The Possible Role of MOPr-DOPr Heteromers and Its Regulatory Protein RTP4 at Sensory Neurons in Relation to Pain Perception.

Authors: Fujita, Wakako

Source: Frontiers in Cellular Neuroscience; 11/13/2020, Vol. 14, pN.PAG-N.PAG, 7p

Subject Terms: SENSORY neurons, DORSAL root ganglia, CARRIER proteins, OPIOID receptors, PAIN management, CHRONIC pain, PAIN perception