Durable Response in Patients With Refractory Fistulizing Perianal Crohn's Disease Using Autologous Mesenchymal Stem Cells on a Dissolvable Matrix: Results from the Phase I Stem Cell on Matrix Plug Trial

Authors: Dozois, Eric J., Lightner, Amy L., Dietz, Allan B., Fletcher, Joel G., Lee, Yong S., Friton, Jessica J., Faubion, William A.

Source: Diseases of the colon & rectum. 66(2):243-252

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178083927.0x000001&indx=1&recIds=ETOCvdc_100178083927.0x000001

Novel Genetic Variant Predicts Surgical Recurrence Risk in Crohn's Disease Patients

Authors: Wang, Ming-Hsi, Friton, Jessica J, Raffals, Laura E, Leighton, Jonathan A, Pasha, Shabana F, Picco, Michael F, Monroe, Kelly, Nix, Billy D, Newberry, Rodney D, Faubion, William A

Source: Inflammatory bowel diseases. 27(12):1968-1974

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135740309.0x000001&indx=1&recIds=ETOCvdc_100135740309.0x000001

Sa1929 MULTIPARAMETER FLOW CYTOMETRY GENERATED IMMUNE PROFILES CORRELATE WITH CROHN'S DISEASE BEHAVIOR, ONSET AGE, SURGICAL OUTCOMES, AND BIOLOGIC THERAPY RESPONSE

Authors: Kurdi, Ahmed T., Nair, Asha, Sun, Zhifu, Friton, Jessica J., Dietz, Allan, Faubion, William

Source: Gastroenterology. 164(6):S-484-S-484

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194410097.0x000001&indx=1&recIds=ETOCvdc_100194410097.0x000001

Altered Bile Acid and Pouch Microbiota Composition in Patients With Chronic Pouchitis.

Authors: Santiago, Priscila, Quinn, Kevin P, Chen, Jun, Friton, Jessica J, Rypstra, Chad R, Kashyap, Purna C, Raffals, Laura E

Source: Inflammatory Bowel Diseases; Jul2024, Vol. 30 Issue 7, p1062-1070, 9p

Su1523: MULTIPARAMETER FLOW CYTOMETRIC IMMUNE PROFILING CORRELATES WITH ENDOSCOPIC ACTIVITY AND RESPONSE TO THERAPY IN CROHN'S DISEASE.

Authors: Kurdi, Ahmed T., Bornschlegl, Svetlana, Sun, Zhifu, Friton, Jessica J., Dietz, Allan, Faubion, William

Source: Gastroenterology. 162(7):S-613-S-613

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167638122.0x000001&indx=1&recIds=ETOCvdc_100167638122.0x000001

Mo1786 THE NATURAL HISTORY OF RECTOVAGINAL AND POUCH-VAGINAL FISTULAS IN CROHN' S DISEASE

Authors: Barros, Luísa L., Vincent, Matthew, Friton, Jessica J., Onken, Bailey M., Gomaa, Ibrahim A., Jin, Mauricio F., Zheng, Clark R., Kassmeyer, Blake A., Lennon, Ryan J., Mathis, Kellie L., Faubion, William, Chedid, Victor G.

Source: Gastroenterology. 164(6):S-910-S-911

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194465650.0x000001&indx=1&recIds=ETOCvdc_100194465650.0x000001

Sa1798 IDENTIFICATION OF A NOVEL SUBGROUP OF CROHN'S DISEASE PATIENTS THROUGH A DIMENTIONALITY REDUCTION APPROACH USING EXOME SEQUENCING DATA

Authors: Wang, Ming-Hsi, Sarangi, Vivekananda, Friton, Jessica J., Severson, Daniel J., Tremaine, William J., Sun, Zhifu, Timmons, Lawrence, Lazaridis, Konstantinos N., Faubion, William

Source: Gastroenterology. 164(6):S-436-S-437

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194412674.0x000001&indx=1&recIds=ETOCvdc_100194412674.0x000001

The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD)

Authors: Sarmento, Olga F., Svingen, Phyllis A., Xiong, Yuning, Sun, Zhifu, Bamidele, Adebowale O., Mathison, Angela J., Smyrk, Thomas C., Nair, Asha A., Gonzalez, Michelle M., Sagstetter, Mary R., Baheti, Saurabh, McGovern, Dermot P.B., Friton, Jessica J., Papadakis, Konstantinos A., Gautam, Goel ^**, Xavier, Ramnik J. ^**, Urrutia, Raul A., Faubion, William A.

Source: In Journal of Biological Chemistry 13 January 2017 292(2):706-722

Sa526 DNA METHYLATION LANDSCAPE AND SIGNATURE OF CD4+ LYMPHOCYTES IN CROHN'S PATIENTS BY REDUCED REPRESENTATION AND BISULFITE SEQUENCING

Authors: Sun, Zhifu, Neto, Manuel Bonfim Braga, Xiong, Yuning, Baheti, Saurabh, Friton, Jessica J., Nair, Asha, Sagstetter, Mary R., Ye, Zhenqing, Faubion, William

Source: Gastroenterology. 160(6):S-536-S-536

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140840954.0x000001&indx=1&recIds=ETOCvdc_100140840954.0x000001

Su1561: POLYGENIC RISK SCORE INDEPENDENTLY INFLUENCES PSC RISK IN ULCERATIVE COLITIS BUT NOT CROHN'S DISEASE

Authors: Wang, Ming-Hsi, Friton, Jessica J., Raffals, Laura H., Leighton, Jonathan A., Newberry, Rodney D., Faubion, William

Source: Gastroenterology. 162(7):S-630-S-631

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167638586.0x000001&indx=1&recIds=ETOCvdc_100167638586.0x000001

586: ASSESSMENT OF BILE ACID COMPOSITION AND POUCH MICROBIOTA IN PATIENTS WITH CHRONIC POUCHITIS

Authors: Santiago, Priscila, Quinn, Kevin, Chen, Jun, Friton, Jessica J., Rypstra, Chad, Raffals, Laura H.

Source: Gastroenterology. 162(7):S-144-S-145

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167623189.0x000001&indx=1&recIds=ETOCvdc_100167623189.0x000001

Tu1198 EPIGENETIC MODULATION OF REGULATORY T CELL FUNCTION BY UBIQUITIN SPECIFIC PROTEASE 22

Authors: Chiang, David, Hamdan, Feda H., Klatt, Emily, Davidson, Heidi, Sagstetter, Mary R., Friton, Jessica J., Mopuri, Rohini, Sun, Zhifu, Gonzalez, Michelle, Druliner, Brooke R., Faubion, William

Source: In Gastroenterology 18-21 May 2024 166(5) Supplement:S

334 EPIGENETIC MEMORY OF INTESTINAL EPITHELIAL CELLS IN INFLAMMATORY BOWEL DISEASE

Authors: Hamdan, Feda H., Gonzalez, Michelle, Chiang, David, Klatt, Emily, Fedyshyn, Yaroslav, Kossick, Kimberlee, Sagstetter, Mary R., Friton, Jessica J., English, Alana, Mopuri, Rohini, Bhagwate, Aditya V., Sun, Zhifu, Faubion, William, Druliner, Brooke R.

Source: In Gastroenterology 18-21 May 2024 166(5) Supplement:S

Polygenic risk score predicts risk of primary sclerosing cholangitis in inflammatory bowel disease.

Authors: Ming-Hsi Wang, Friton, Jessica J., Raffals, Laura E., Leighton, Jonathan A., Pasha, Shabana F., Picco, Michael F., Monroe, Kelly, Nix, Billy D., Newberry, Rodney D., Faubion, William A.

Source: BMJ Open Gastroenterology; 2023, Vol. 10 Issue 1, p1-6, 6p

15 DISRUPTION OF FOXP3-EZH2 INTERACTION BY GENETIC MUTATION OR SIGNALING-INDUCED INACTIVATION REPRESENTS A NOVEL PATHOBIOLOGICAL MECHANISM IN INFLAMMATORY BOWEL DISEASE

Authors: Bamidele, Adebowale O, Svingen, Phyllis A, Sagstetter, Mary R, Gonzalez, Michelle, Sarmento, Olga F, Braga Neto, Manuel B, Friton, Jessica J, Kugathasan, Subra, Lomberk, Gwen, Urrutia, Raul A, Faubion, William A

Source: Inflammatory bowel diseases. 24(1):S10-S11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100078250895.0x000001&indx=1&recIds=ETOCvdc_100078250895.0x000001

RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease

Authors: Kosinsky, Robyn Laura, Zerche, Maria, Kutschat, Ana Patricia, Nair, Asha, Ye, Zhenqing, Saul, Dominik, von Heesen, Maximilian, Friton, Jessica J., Schwarzer, Ana Carolina, Paglilla, Nadia, Sheikh, Shehzad Z., Wegwitz, Florian, Sun, Zhifu, Ghadimi, Michael, Newberry, Rodney D., Sartor, R. Balfour, Faubion, William A., Johnsen, Steven A.

Source: Cell Death and Differentiation; November 2021, Vol. 28 Issue: 11 p3161-3175, 15p

Unique Phenotypic Characteristics and Clinical Course in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis: A Multicenter US Experience.

Authors: Wang, Ming-Hsi, Mousa, Omar Y, Friton, Jessica J, Raffals, Laura E, Leighton, Jonathan A, Pasha, Shabana F, Picco, Michael F, Cushing, Kelly C, Monroe, Kelly, Nix, Billy D, Newberry, Rodney D, Faubion, William A

Source: Inflammatory Bowel Diseases; May2020, Vol. 26 Issue 5, p774-779, 6p

Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients With Inflammatory Bowel Disease.

Authors: Wang, Ming-Hsi, Friton, Jessica J, Raffals, Laura E, Leighton, Jonathan A, Pasha, Shabana F, Picco, Michael F, Cushing, Kelly C, Monroe, Kelly, Nix, Billy D, Newberry, Rodney D, Faubion, William A

Source: Journal of Crohn's & Colitis; Aug2019, Vol. 13 Issue 8, p1036-1043, 8p

Early Results of a Phase I Trial Using an Adipose-Derived Mesenchymal Stem Cell-Coated Fistula Plug for the Treatment of Transsphincteric Cryptoglandular Fistulas.

Authors: Dozois, Eric J., Lightner, Amy L., Mathis, Kellie L., Chua, Heidi K., Kelley, Scott R., Fletcher, Joel G., Dietz, Allan B., Friton, Jessica J., Butler, Greg W., Faubion, William A.

Source: Diseases of the Colon & Rectum; May2019, Vol. 62 Issue 5, p615-622, 8p

15 DISRUPTION OF FOXP3-EZH2 INTERACTION BY GENETIC MUTATION OR SIGNALING-INDUCED INACTIVATION REPRESENTS A NOVEL PATHOBIOLOGICAL MECHANISM IN INFLAMMATORY BOWEL DISEASE

Authors: Bamidele, Adebowale O., Svingen, Phyllis A., Sagstetter, Mary R., Gonzalez, Michelle, Sarmento, Olga F., Braga Neto, Manuel B., Friton, Jessica J., Kugathasan, Subra, Lomberk, Gwen, Urrutia, Raul A., Faubion, William A., Jr.

Source: In Gastroenterology January 2018 154(1) Supplement:S15-S15