A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations

Authors: Bertoglio, Federico, Fühner, Viola, Ruschig, Maximilian, Heine, Philip Alexander, Abassi, Leila, Klünemann, Thomas, Rand, Ulfert, Meier, Doris, Langreder, Nora, Steinke, Stephan, Ballmann, Rico, Schneider, Kai-Thomas, Roth, Kristian Daniel Ralph, Kuhn, Philipp, Riese, Peggy, Schäckermann, Dorina, Korn, Janin, Koch, Allan, Chaudhry, M. Zeeshan, Eschke, Kathrin, Kim, Yeonsu, Zock-Emmenthal, Susanne, Becker, Marlies, Scholz, Margitta, Moreira, Gustavo Marçal Schmidt Garcia, Wenzel, Esther Veronika, Russo, Giulio, Garritsen, Hendrikus S.P., Casu, Sebastian, Gerstner, Andreas, Roth, Günter, Adler, Julia, Trimpert, Jakob, Hermann, Andreas, Schirrmann, Thomas, Dübel, Stefan, Frenzel, André, Van den Heuvel, Joop, Čičin-Šain, Luka, Schubert, Maren, Hust, Michael

Source: In Cell Reports 27 July 2021 36(4)

Effects of a Multimerized Recombinant Autoantibody Against Amyloid-β

Authors: Albus, Alexandra, Kronimus, Yannick, Neumann, Sascha, Vidovic, Natascha, Frenzel, André, Kuhn, Philipp, Seifert, Marc, Ziehm, Tamar, van der Wurp, Hendrik, Dodel, Richard

Source: In Neuroscience 21 May 2021 463:355-369

Regulatory T cells engineered with a novel insulin-specific chimeric antigen receptor as a candidate immunotherapy for type 1 diabetes

Authors: Tenspolde, Michel, Zimmermann, Katharina, Weber, Leonie C., Hapke, Martin, Lieber, Maren, Dywicki, Janine, Frenzel, Andre, Hust, Michael, Galla, Melanie, Buitrago-Molina, Laura E., Manns, Michael P., Jaeckel, Elmar, Hardtke-Wolenski, Matthias

Source: In Journal of Autoimmunity September 2019 103

Antibody Phage Display: Antibody Selection in Solution Using Biotinylated Antigens

Authors: Wenzel, Esther V., Roth, Kristian D. R., Russo, Giulio, Fühner, Viola, Helmsing, Saskia, Frenzel, André, Hust, Michael

Source: Methods in molecular biology. 2070:143-156

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622112369&indx=1&recIds=ETOCRN622112369

A One-Step Process for the Construction of Phage Display scFv and VHH Libraries

Authors: Sellmann, Carolin, Pekar, Lukas, Bauer, Christina, Ciesielski, Elke, Krah, Simon, Becker, Stefan, Toleikis, Lars, Kügler, Jonas, Frenzel, André, Valldorf, Bernhard, Hust, Michael, Zielonka, Stefan

Source: Molecular biotechnology. 62(4):228-239

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164383321.0x000001&indx=1&recIds=ETOCvdc_100164383321.0x000001

Rekombinante, vollständig humane Antikörper zur Behandlung akuter COVID-19

Authors: Dübel, Stefan, Hust, Michael, Frenzel, André, Schirrmann, Thomas

Source: Biospektrum. 26(4):444-446

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172222042.0x000001&indx=1&recIds=ETOCvdc_100172222042.0x000001

Antibody Affinity and Stability Maturation by Error-Prone PCR

Authors: Unkauf, Tobias, Hust, Michael, Frenzel, André

Source: Methods in molecular biology. 1701:393-410

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN613748294&indx=1&recIds=ETOCRN613748294

Parallelized Antibody Selection in Microtiter Plates

Authors: Russo, Giulio, Meier, Doris, Helmsing, Saskia, Wenzel, Esther, Oberle, Fabian, Frenzel, André, Hust, Michael

Source: Methods in molecular biology. 1701:273-284

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN613748219&indx=1&recIds=ETOCRN613748219

Construction of Human Immune and Naive scFv Libraries

Authors: Kügler, Jonas, Tomszak, Florian, Frenzel, André, Hust, Michael

Source: Methods in molecular biology. 1701:3-24

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN613748087&indx=1&recIds=ETOCRN613748087

Phage Display and Selections on Cells

Authors: Fahr, Wieland, Frenzel, André

Source: Methods in molecular biology. 1701:321-330

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN613748244&indx=1&recIds=ETOCRN613748244

Designing Human Antibodies by Phage Display

Authors: Frenzel, André, Kügler, Jonas, Helmsing, Saskia, Meier, Doris, Schirrmann, Thomas, Hust, Michael, Dübel, Stefan

Source: Transfusion medicine and hemotherapy. 44(5):312-318

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084825914.0x000001&indx=1&recIds=ETOCvdc_100084825914.0x000001

Selection of Recombinant Human Antibodies

Authors: Tomszak, Florian, Weber, Susanne, Zantow, Jonas, Schirrmann, Thomas, Hust, Michael, Frenzel, André

Source: Advances in experimental medicine and biology. 917:23-54

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN606543333&indx=1&recIds=ETOCRN606543333

Generation of Recombinant Antibodies Against Toxins and Viruses by Phage Display for Diagnostics and Therapy

Authors: Unkauf, Tobias, Miethe, Sebastian, Fühner, Viola, Schirrmann, Thomas, Frenzel, André, Hust, Michael

Source: Advances in experimental medicine and biology. 917:55-76

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN606543345&indx=1&recIds=ETOCRN606543345

Phage display-derived human antibodies in clinical development and therapy

Authors: Frenzel, André, Schirrmann, Thomas, Hust, Michael

Source: MAbs. 8(7):1177-1194

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100036128617.0x000001&indx=1&recIds=ETOCvdc_100036128617.0x000001

Novel NKG2D-directed bispecific antibodies enhance antibodymediated killing of malignant B cells by NK cells and T cells.

Authors: Lutz, Sebastian, Klausz, Katja, Albici, Anca-Maria, Ebinger, Lea, Sellmer, Lea, Teipel, Hannah, Frenzel, André, Langner, Anna, Winterberg, Dorothee, Krohn, Steffen, Hust, Michael, Schirrmann, Thomas, Dübel, Stefan, Scherließ, Regina, Humpe, Andreas, Gramatzki, Martin, Kellner, Christian, Peipp, Matthias

Source: Frontiers in Immunology; 2023, p1-13, 13p

Subject Terms: KILLER cells, BISPECIFIC antibodies, CANCER cells, T cells, B cells, INTERLEUKIN-21, GRANZYMES

Evaluation of the Neutralizing Antibody STE90-C11 against SARS-CoV-2 Delta Infection and Its Recognition of Other Variants of Concerns.

Authors: Abassi, Leila, Bertoglio, Federico, Mačak Šafranko, Željka, Schirrmann, Thomas, Greweling-Pils, Marina, Seifert, Oliver, Khan, Fawad, Katzmarzyk, Maeva, Jacobsen, Henning, Gödecke, Natascha, Heine, Philip Alexander, Frenzel, André, Nowack, Helena, Dübel, Stefan, Kurolt, Ivan-Christian, Kontermann, Roland E., Markotić, Alemka, Schubert, Maren, Hust, Michael, Čičin-Šain, Luka

Source: Viruses (1999-4915); Nov2023, Vol. 15 Issue 11, p2153, 18p

Subject Terms: SARS-CoV-2 Delta variant, BISPECIFIC antibodies, SARS-CoV-2 Omicron variant, VIRAL antigens, VIRAL antibodies, GENETIC vectors, AVIAN influenza

The conserved arbuscular mycorrhiza-specific transcription of the secretory lectin MtLec5 is mediated by a short upstream sequence containing specific protein binding sites.

Authors: Frenzel, André, Tiller, Nadine, Hause, Bettina

Source: Planta; September 2006, Vol. 224 Issue 4, p792-800, 9p

Production of single chain fragment variable (scFv) antibodies in Escherichia coli using the LEX™ bioreactor

Authors: Miethe, Sebastian, Meyer, Torsten, Wöhl-Bruhn, Stefanie, Frenzel, André, Schirrmann, Thomas, Dübel, Stefan, Hust, Michael

Source: In Journal of Biotechnology 20 January 2013 163(2):105-111

Structural differences of amyloid-β fibrils revealed by antibodies from phage display

Authors: Droste, Patrick, Frenzel, André, Steinwand, Miriam, Pelat, Thibaut, Thullier, Philippe, Hust, Michael, Lashuel, Hilal, Dübel, Stefan

Source: BMC biotechnology. 15(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140460683.0x000001&indx=1&recIds=ETOCvdc_100140460683.0x000001

Evaluation of human pancreatic RNase as effector molecule in a therapeutic antibody platform

Authors: Schirrmann, Thomas, Frenzel, André, Linden, Lars, Stelte-Ludwig, Beatrix, Willuda, Jörg, Harrenga, Axel, Dübel, Stefan, Müller-Tiemann, Beate, Trautwein, Mark

Source: MAbs. 6(2):367-380

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050682233.0x000001&indx=1&recIds=ETOCvdc_100050682233.0x000001