Tropomyosin 1 deficiency facilitates cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis

Authors: Wilken, Madison B., Fonar, Gennadiy, Qiu, Rong, Bennett, Laura, Tober, Joanna, Nations, Catriana, Pavani, Giulia, Tsao, Victor, Garifallou, James, Petit, Chayanne, Maguire, Jean Ann, Gagne, Alyssa, Okoli, Nkemdilim, Gadue, Paul, Chou, Stella T., French, Deborah L., Speck, Nancy A., Thom, Christopher S.

Source: In Stem Cell Reports 10 September 2024 19(9):1264-1276

Cross-site reproducibility of human cortical organoids reveals consistent cell type composition and architecture

Authors: Glass, Madison R., Waxman, Elisa A., Yamashita, Satoshi, Lafferty, Michael, Beltran, Alvaro A., Farah, Tala, Patel, Niyanta K., Singla, Rubal, Matoba, Nana, Ahmed, Sara, Srivastava, Mary, Drake, Emma, Davis, Liam T., Yeturi, Meghana, Sun, Kexin, Love, Michael I., Hashimoto-Torii, Kazue, French, Deborah L., Stein, Jason L.

Source: In Stem Cell Reports 10 September 2024 19(9):1351-1367

Rigor and reproducibility in human brain organoid research: Where we are and where we need to go

Authors: Anderson, Stewart, Anita, Bhattacharyya, Buttermore, Elizabeth, Chang, Qiang, French, Deborah, Hashimoto-Torii, Kazue, Kornblum, Harley, Kroll, Kristin, Lachman, Herbert M., Maletic-Savatic, Mirjana, Niciu, Mark, Novitch, Bennett, Padmanabhan, Krishnan, Proschel, Chris, Sahin, Mustafa, Sousa, Andre, Stein, Jason, Wang, Daifeng, Waxman, Elisa, Whye, Dosh, Williams, Aislinn, Zhao, Xinyu, Sandoval, Soraya O., Cappuccio, Gerarda, Kruth, Karina, Osenberg, Sivan, Khalil, Saleh M., Méndez-Albelo, Natasha M., Niciu, Mark J., Bhattacharyya, Anita, Stein, Jason L., Sousa, André M.M., Waxman, Elisa A., Buttermore, Elizabeth D., Sirois, Carissa L.

Source: In Stem Cell Reports 11 June 2024 19(6):796-816

Modeling primitive and definitive erythropoiesis with induced pluripotent stem cells

Authors: Pavani, Giulia, Klein, Joshua G., Nations, Catriana C., Sussman, Jonathan H., Tan, Kai, An, Hyun Hyung, Abdulmalik, Osheiza, Thom, Christopher S., Gearhart, Peter A., Willett, Camryn M., Maguire, Jean Ann, Chou, Stella T., French, Deborah L., Gadue, Paul

Source: In Blood Advances 26 March 2024 8(6):1449-1463

Megakaryocyte-induced contraction of plasma clots: cellular mechanisms and structural mechanobiology

Authors: Kim, Oleg V., Litvinov, Rustem I., Gagne, Alyssa L., French, Deborah L., Brass, Lawrence F., Weisel, John W.

Source: In Blood 8 February 2024 143(6):548-560

A novel iPSC model reveals selective vulnerability of neurons in multiple sulfatase deficiency

Authors: Pham, Vi, Sertori Finoti, Livia, Cassidy, Margaret M., Maguire, Jean Ann, Gagne, Alyssa L., Waxman, Elisa A., French, Deborah L., King, Kaitlyn, Zhou, Zitao, Gelb, Michael H., Wongkittichote, Parith, Hong, Xinying, Schlotawa, Lars, Davidson, Beverly L., Ahrens-Nicklas, Rebecca C.

Source: In Molecular Genetics and Metabolism February 2024 141(2)

Clinical utility of laboratory developed mass spectrometry assays for steroid hormone testing

Authors: French, Deborah

Source: Journal of Mass Spectrometry and Advances in the Clinical Lab. 28:13-19

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190027244.0x000001&indx=1&recIds=ETOCvdc_100190027244.0x000001

Cannabis positivity rates in 17 emergency departments across the United States with varying degrees of marijuana legalization

Authors: Tolan, Nicole V., Krasowski, Matthew D., Mathias, Patrick C., Wiencek, Joesph R., Babic, Nikolina, Chai, Peter R., Chambliss, Allison B., Choucair, Ibrahim, Demetriou, Christiana A., Erickson, Timothy B., Feldhammer, Matthew, French, Deborah, Hayes, Bryan D., Kang, Phillip, El-Khoury, Joe M., Knezevic, Claire E., Monte, Andrew, Nerenz, Robert D., Okorodudu, Anthony O., Roper, Stephen M., Saitman, Alec, Thiriveedhi, Vamsi, Uljon, Sacha N., Vest, Alexis, Woodworth, Alison, Yu, Min, Melanson, Stacy E. F.

Source: Clinical toxicology. 61(4):248-259

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184893329.0x000001&indx=1&recIds=ETOCvdc_100184893329.0x000001

Platelet findings in 22q11.2 deletion syndrome correlate with disease manifestations but do not correlate with GPIb surface expression

Authors: Campbell, Ian M., Crowley, T. Blaine, Jobaliya, Chintan, Bailey, Alice, McGinn, Daniel E., Gaiser, Kimberly, Bassett, Anne, Gur, Raquel E., Morrow, Bernice, Emanuel, Beverly S., Franco, Aime T., French, Deborah, Zackai, Elaine H., McDonald‐McGinn, Donna M., Lambert, Michele P.

Source: Clinical genetics. 103(1):109-113

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169051749.0x000001&indx=1&recIds=ETOCvdc_100169051749.0x000001

The use of pluripotent stem cells to generate diagnostic tools for transfusion medicine

Authors: An, Hyun Hyung, Gagne, Alyssa L., Maguire, Jean Ann, Pavani, Giulia, Abdulmalik, Osheiza, Gadue, Paul, French, Deborah L., Westhoff, Connie M., Chou, Stella T.

Source: In Blood 13 October 2022 140(15):1723-1734

Reduced Immune Response and Neutralizing Antibody Activity to the SARS-CoV-2 Vaccination in Patients with a History of Solid Organ Transplant

Authors: French, Deborah, Ong, Chui Mei, Patel, Paul, Zuk, Marisa, Wu, Alan H B

Source: Laboratory medicine. 53(5):514-522

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159692646.0x000001&indx=1&recIds=ETOCvdc_100159692646.0x000001

Genome Engineering Human ESCs or iPSCs with Cytosine and Adenine Base Editors

Authors: Pavani, Giulia, Klein, Joshua G., French, Deborah L., Gadue, Faul

Source: Methods in molecular biology. 2520:321-334

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629848318&indx=1&recIds=ETOCRN629848318

Is the Best Drug Test the Enemy of the Good STAT Toxicology Screen?

Authors: Stone, Judith A, French, Deborah

Source: Journal of applied laboratory medicine. 7(2):401-405

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142902109.0x000001&indx=1&recIds=ETOCvdc_100142902109.0x000001

Defective RAB31-mediated megakaryocytic early endosomal trafficking of VWF, EGFR, and M6PR in RUNX1 deficiency

Authors: Jalagadugula, Gauthami ^*, Mao, Guangfen ^*, Goldfinger, Lawrence E. ^*, Wurtzel, Jeremy, Del Carpio-Cano, Fabiola, Lambert, Michele P., Estevez, Brian, French, Deborah L., Poncz, Mortimer, Rao, A. Koneti ^*

Source: In Blood Advances 13 September 2022 6(17):5100-5112

PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes

Authors: Wickramasinghe, Nadeera M., Sachs, David, Shewale, Bhavana, Gonzalez, David M., Dhanan-Krishnan, Priyanka, Torre, Denis, LaMarca, Elizabeth, Raimo, Serena, Dariolli, Rafael, Serasinghe, Madhavika N., Mayourian, Joshua, Sebra, Robert, Beaumont, Kristin, Iyengar, Srinivas, French, Deborah L., Hansen, Arne, Eschenhagen, Thomas, Chipuk, Jerry E., Sobie, Eric A., Jacobs, Adam, Akbarian, Schahram, Ischiropoulos, Harry, Ma’ayan, Avi, Houten, Sander M., Costa, Kevin, Dubois, Nicole C.

Source: In Cell Stem Cell 7 April 2022 29(4):559-576

The effect of the Covid-19 shutdown on glycemic testing and control

Authors: Sharma, Anu, Greene, Dina N., Chambliss, Allison B., Farnsworth, Christopher W., French, Deborah, Herman, Daniel S., Kavsak, Peter A., Merrill, Anna E., (Margaret) Lo, Sheng-Ying, Lyon, Martha E., Winston-McPherson, Gabrielle, Pearson, Lauren N., SoRelle, Jeffrey A., Waring, Avantika C., Schmidt, Robert L.

Source: In Clinica Chimica Acta August 2021 519:148-152

RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells

Authors: Estevez, Brian, Borst, Sara, Jarocha, Danuta, Sudunagunta, Varun, Gonzalez, Michael, Garifallou, James, Hakonarson, Hakon, Gao, Peng, Tan, Kai, Liu, Paul, Bagga, Sumedha, Holdreith, Nicholas, Tong, Wei, Speck, Nancy, French, Deborah L., Gadue, Paul, Poncz, Mortimer ^*

Source: In Blood 13 May 2021 137(19):2662-2675

Restoring RUNX1 deficiency in RUNX1 familial platelet disorder by inhibiting its degradation

Authors: Krutein, Michelle C. ^*, Hart, Matthew R. ^*, Anderson, Donovan J., Jeffery, Jasmin, Kotini, Andriana G., Dai, Jin, Chien, Sylvia, DelPriore, Michaela, Borst, Sara, Maguire, Jean Ann, French, Deborah L., Gadue, Paul, Papapetrou, Eirini P., Keel, Siobán B., Becker, Pamela S., Horwitz, Marshall S.

Source: In Blood Advances 9 February 2021 5(3):687-699

Derivation and investigation of the first human cell-based model of Beckwith-Wiedemann syndrome

Authors: Chang, Suhee, Hur, Stella K., Naveh, Natali S. Sobel, Thorvaldsen, Joanne L., French, Deborah L., Gagne, Alyssa L, Jobaliya, Chintan D., Anguera, Montserrat C., Bartolomei, Marisa S., Kalish, Jennifer M

Source: Epigenetics. 16(12):1295-1305

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135649230.0x000001&indx=1&recIds=ETOCvdc_100135649230.0x000001

Modeling genetic platelet disorders with human pluripotent stem cells: mega-progress but wanting more on our plate(let)

Authors: Nations, Catriana C., Pavani, Giulia, French, Deborah L., Gadue, Paul

Source: Current opinion in hematology. 28(5):308-314

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123810956.0x000001&indx=1&recIds=ETOCvdc_100123810956.0x000001