The role of complement in kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Authors: Alberici, Federico, Antonucci, Luca, Avcin, Tadej, Bagga, Arvind, Bajema, Ingeborg M., Blasco, Miquel, Chauvet, Sophie, Cook, H. Terence, Cravedi, Paolo, Dragon-Durey, Marie-Agnès, Fischer, Lauren, Fogo, Agnes B., Frazer-Abel, Ashley, Frémeaux-Bacchi, Véronique, Görlich, Nina, Haas, Mark, Humphreys, Alister, Jha, Vivekanand, Jauhal, Arenn, Kavanagh, David, Kronbichler, Andreas, Lafayette, Richard A., Lanning, Lynne D., Lemaire, Mathieu, Le Quintrec, Moglie, Licht, Christoph, Liew, Adrian, McAdoo, Steve, Medjeral-Thomas, Nicholas R., Meroni, Pier Luigi, Morelle, Johann, Nester, Carla M., Praga, Manuel, Ramachandran, Raja, Reich, Heather N., Remuzzi, Giuseppe, Rodríguez de Córdoba, Santiago, Robinson, Gary, Ronco, Pierre, Rossing, Peter, Salant, David J., Sethi, Sanjeev, Silkjaer, Marianne, Song, Wen-chao, Spoleti, Fabrizio, Taylor, Ronald P., van de Kar, Nicole C.A.J., van Kooten, Cees, Woodward, Len, Zhang, Yuzhou, Zipfel, Peter F., Zuccato, Marco, Vivarelli, Marina, Barratt, Jonathan, Beck, Laurence H., Jr., Fakhouri, Fadi, Gale, Daniel P., Goicoechea de Jorge, Elena, Mosca, Marta, Noris, Marina, Pickering, Matthew C., Susztak, Katalin, Thurman, Joshua M., Cheung, Michael, King, Jennifer M., Jadoul, Michel, Winkelmayer, Wolfgang C., Smith, Richard J.H.

Source: In Kidney International September 2024 106(3):369-391

Thrombotic Microangiopathy as an Emerging Complication of Viral Vector–Based Gene Therapy

Authors: Schwotzer, Nora, El Sissy, Carine, Desguerre, Isabelle, Frémeaux-Bacchi, Véronique, Servais, Laurent, Fakhouri, Fadi

Source: In Kidney International Reports July 2024 9(7):1995-2005

De novo thrombotic microangiopathy after kidney transplantation in adults: Interplay between complement genetics and multiple endothelial injury

Authors: Dessaix, Kathleen, Bontoux, Christophe, Aubert, Olivier, Grünenwald, Anne, Sberro Soussan, Rebecca, Zuber, Julien, Duong Van Huyen, Jean-Paul, Anglicheau, Dany, Legendre, Christophe, Fremeaux Bacchi, Veronique, Rabant, Marion

Source: In American Journal of Transplantation July 2024 24(7):1205-1217

Usefulness and analytical performances of complement multiplex assay for measuring complement biomarkers in plasma

Authors: Meuleman, Marie-Sophie, Duval, Anna, Grunenwald, Anne, Rezola Artero, Mikel, Dermani, Mohamed, Peliconi, Julie, Revel, Margot, Vieira-Martins, Paula, Courbebaisse, Marie, Parfait, Béatrice, Lebeaux, David, Friedlander, Gérard, Roumenina, Lubka, Chauvet, Sophie, Frémeaux-Bacchi, Véronique, Dragon-Durey, Marie-Agnès

Source: In Clinica Chimica Acta 1 February 2024 554

Complement in human disease: approved and up-and-coming therapeutics

Authors: West, Erin E, Woodruff, Trent, Fremeaux-Bacchi, Veronique, Kemper, Claudia ^*

Source: In The Lancet 27 January-2 February 2024 403(10424):392-405

Alternative pathway diagnostics

Authors: Thurman, Joshua M., Fremeaux‐Bacchi, Veronique

Source: Immunological reviews. 313(1):225-238

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171090050.0x000001&indx=1&recIds=ETOCvdc_100171090050.0x000001

C3 Glomerulopathy With Concurrent Thrombotic Microangiopathy: Clinical and Immunological Features

Authors: Chabannes, Melchior, Rabant, Marion, El Sissy, Carine, Dragon-Durey, Marie-Agnès, Vieira Martins, Paula, Meuleman, Marie Sophie, Karras, Alexandre, Buob, David, Bridoux, Frank, Daugas, Eric, Audard, Vincent, Caillard, Sophie, Olagne, Jérôme, Kandel, Christine, Ferlicot, Sophie, Philipponnet, Carole, Crepin, Thomas, Thervet, Eric, Ducloux, Didier, Frémeaux-Bacchi, Véronique, Chauvet, Sophie

Source: In American Journal of Kidney Diseases September 2023 82(3):279-289

How I diagnose and treat atypical hemolytic uremic syndrome

Authors: Fakhouri, Fadi, Schwotzer, Nora, Frémeaux-Bacchi, Véronique

Source: In Blood 2 March 2023 141(9):984-995

Exome-First Strategy in Adult Patients With CKD: A Cohort Study

Authors: Doreille, Alice, Lombardi, Yannis, Dancer, Marine, Lamri, Radoslava, Testard, Quentin, Vanhoye, Xavier, Lebre, Anne-Sophie, Garcia, Hugo, Rafat, Cédric, Ouali, Nacera, Luque, Yosu, Izzedine, Hassan, Esteve, Emmanuel, Cez, Alexandre, Petit-Hoang, Camille, François, Hélène, Marchal, Armance, Letavernier, Emmanuel, Frémeaux-Bacchi, Véronique, Boffa, Jean-Jacques, Rondeau, Eric, Raymond, Laure, Mesnard, Laurent

Source: In Kidney International Reports March 2023 8(3):596-605

Results from a nationwide retrospective cohort measure the impact of C3 and soluble C5b-9 levels on kidney outcomes in C3 glomerulopathy

Authors: Chauvet, Sophie, Hauer, Jill J., Petitprez, Florent, Rabant, Marion, Martins, Paula Vieira, Baudouin, Véronique, Delmas, Yahsou, Jourde-Chiche, Noémie, Cez, Alexandre, Ribes, David, Cloarec, Sylvie, Servais, Aude, Zaidan, Mohamad, Daugas, Eric, Delahousse, Michel, Wynckel, Alain, Ryckewaert, Amélie, Sellier-Leclerc, Anne Laure, Boyer, Olivia, Thervet, Eric, Karras, Alexandre, Smith, Richard J.H., Frémeaux-Bacchi, Véronique

Source: In Kidney International October 2022 102(4):904-916

Improving Clinical Trials for Anticomplement Therapies in Complement-Mediated Glomerulopathies: Report of a Scientific Workshop Sponsored by the National Kidney Foundation

Authors: Bomback, Andrew S., Appel, Gerald B., Gipson, Debbie S., Hladunewich, Michelle A., Lafayette, Richard, Nester, Carla M., Parikh, Samir V., Smith, Richard J.H., Trachtman, Howard, Heeger, Peter S., Ram, Sanjay, Rovin, Brad H., Ali, Shadab, Arceneaux, Nicole, Ashoor, Isa, Bailey-Wickins, Laura, Barratt, Jonathan, Beck, Laurence, Cattran, Daniel C., Cravedi, Paolo, Erkan, Elif, Fervenza, Fernando, Frazer-Abel, Ashley A., Fremeaux-Bacchi, Veronique, Fuller, Lindsey, Gbadegesin, Rasheed, Hogan, Jonathan J., Kiryluk, Krzysztof, le Quintrec-Donnette, Moglie, Licht, Christoph, Mahan, John D., Pickering, Matthew C., Quigg, Richard, Rheault, Michelle, Ronco, Pierre, Sarwal, Minnie M., Sethna, Christine, Spino, Cathie, Stegall, Mark, Vivarelli, Marina, Feldman, David L., Thurman, Joshua M.

Source: American journal of kidney diseases. 79(4):570-581

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157663899.0x000001&indx=1&recIds=ETOCvdc_100157663899.0x000001

Complement Activation and Thrombotic Microangiopathy Associated With Monoclonal Gammopathy: A National French Case Series

Authors: Martins, Manon, Bridoux, Frank, Goujon, Jean Michel, Meuleman, Marie Sophie, Ribes, David, Rondeau, Eric, Guerry, Mary-Jane, Delmas, Yahsou, Levy, Bénédicte, Ducloux, Didier, Kandel-Aznar, Christine, Le Fur, Awena, Garrouste, Cyril, Provot, François, Gibier, Jean-Baptiste, Thervet, Eric, Bruneval, Patrick, Rabant, Marion, Karras, Alexandre, Dragon Durey, Marie Agnès, Fremeaux-Bacchi, Veronique, Chauvet, Sophie

Source: In American Journal of Kidney Diseases September 2022 80(3):341-352

Fatal thrombotic microangiopathy case following adeno-associated viral SMN gene therapy

Authors: Guillou, Julia ^*, de Pellegars, Alice ^*, Porcheret, Florence, Frémeaux-Bacchi, Véronique, Allain-Launay, Emma, Debord, Camille, Denis, Manon, Péréon, Yann, Barnérias, Christine, Desguerre, Isabelle ^*, Roussey, Gwenaëlle ^*, Mercier, Sandra ^*

Source: In Blood Advances 26 July 2022 6(14):4266-4270

The Rational Use of Complement Inhibitors in Kidney Diseases

Authors: Fakhouri, Fadi, Schwotzer, Nora, Golshayan, Déla, Frémeaux-Bacchi, Véronique

Source: In Kidney International Reports June 2022 7(6):1165-1178

Les bloqueurs du complément : nouvelles pistes thérapeutiques en néphrologie

Alternate Title: Complement inhibitors: New treatments for kidney diseases (English)

Authors: Brousse, Romain, Frémeaux-Bacchi, Véronique

Source: In La Presse Médicale Formation April 2022 3(2):177-182

Severe COVID-19 is associated with hyperactivation of the alternative complement pathway

Authors: Boussier, Jeremy, Yatim, Nader, Marchal, Armance, Hadjadj, Jérôme, Charbit, Bruno, El Sissy, Carine, Carlier, Nicolas, Pène, Frédéric, Mouthon, Luc, Tharaux, Pierre-Louis, Bergeron, Anne, Smadja, David M., Rieux-Laucat, Frédéric, Duffy, Darragh, Kernéis, Solen, Frémeaux-Bacchi, Véronique, Terrier, Benjamin

Source: In The Journal of Allergy and Clinical Immunology February 2022 149(2):550-556

Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study

Authors: Fakhouri, Fadi ^*, Fila, Marc, Hummel, Aurélie, Ribes, David, Sellier-Leclerc, Anne-Laure, Ville, Simon, Pouteil-Noble, Claire, Coindre, Jean-Philippe, Le Quintrec, Moglie, Rondeau, Eric, Boyer, Olivia, Provôt, François, Djeddi, Djamal, Hanf, William, Delmas, Yahsou, Louillet, Ferielle, Lahoche, Annie, Favre, Guillaume, Châtelet, Valérie, Launay, Emma Allain, Presne, Claire, Zaloszyc, Ariane, Caillard, Sophie, Bally, Stéphane, Raimbourg, Quentin, Tricot, Leïla, Mousson, Christiane, Le Thuaut, Aurélie, Loirat, Chantal, Frémeaux-Bacchi, Véronique

Source: In Blood 6 May 2021 137(18):2438-2449

Ex Vivo Complement Activation on Endothelial Cells: Research and Translational Value

Authors: Meuleman, Marie-Sophie, Fremeaux-Bacchi, Veronique, Roumenina, Lubka T., Chauvet, Sophie

Source: In Trends in Molecular Medicine May 2021 27(5):418-421

Identification of Distinct Immunophenotypes in Critically Ill Coronavirus Disease 2019 Patients

Authors: Dupont, Thibault, Caillat-Zucman, Sophie, Fremeaux-Bacchi, Véronique, Morin, Florence, Lengliné, Etienne, Darmon, Michael, Peffault de Latour, Régis, Zafrani, Lara, Azoulay, Elie, Dumas, Guillaume

Source: In Chest May 2021 159(5):1884-1893

Role of C5 inhibition in Idiopathic Inflammatory Myopathies and Scleroderma Renal Crisis–Induced Thrombotic Microangiopathies

Authors: Gouin, Anna, Ribes, David, Colombat, Magali, Chauveau, Dominique, Prevot, Gregoire, Lairez, Olivier, Pugnet, Gregory, Fremeaux-Bacchi, Veronique, Huart, Antoine, Belliere, Julie, Faguer, Stanislas

Source: In Kidney International Reports April 2021 6(4):1015-1021