Safety and efficacy of standard-of-care ciltacabtagene autoleucel for relapsed/refractory multiple myeloma

Authors: Sidana, Surbhi ^{1, ∗}, Patel, Krina K. ², Peres, Lauren C. ³, Bansal, Radhika ⁴, Kocoglu, Mehmet H. ⁵, Shune, Leyla ⁶, Atrash, Shebli ⁷, Smith, Kinaya ⁸, Midha, Shonali ⁹, Ferreri, Christopher ⁷, Dhakal, Binod ⁸, Dima, Danai ¹⁰, Costello, Patrick ⁹, Wagner, Charlotte ¹¹, Reshef, Ran ¹², Hosoya, Hitomi ¹, Mikkilineni, Lekha ¹, Atanackovic, Djordje ⁵, Chhabra, Saurabh ¹³, Parrondo, Ricardo ¹⁴, Nadeem, Omar ⁹, Mann, Hashim ¹⁵, Kalariya, Nilesh ², Hovanky, Vanna ¹, De Avila, Gabriel ³, Freeman, Ciara L. ³, Locke, Frederick L. ³, Alsina, Melissa ³, Wong, Sandy ¹⁶, Herr, Megan ¹⁷, Htut, Myo ¹⁸, McGuirk, Joseph ⁶, Sborov, Douglas W. ¹¹, Khouri, Jack ¹⁰, Martin, Thomas ¹⁶, Janakiram, Murali ¹⁸, Lin, Yi ⁴, Hansen, Doris K. ^{3, ∗∗}

Source: In Blood 2 January 2025 145(1):85-97

Tumor burden quantified by soluble B-cell maturation antigen and metabolic tumor volume determines myeloma CAR-T outcomes

Authors: Freeman, Ciara L. ^{1, ∗}, Noble, Jerald ², Menges, Meghan ², Villanueva, Ricardo ³, Nakashima, Justyn Y. ⁴, Figura, Nicholas B. ⁴, Tonseth, Rolf Petter ⁵, Werner Idiaquez, Dietrich ⁶, Skelson, Lawrence ¹, Smith, Eric ¹, Abraham-Miranda, Julieta ², Corallo, Salvatore ², De Avila, Gabriel ², Castaneda Puglianini, Omar A. ¹, Liu, Hien ¹, Alsina, Melissa ¹, Nishihori, Taiga ¹, Shain, Kenneth H. ⁷, Baz, Rachid ⁷, Blue, Brandon ⁷, Grajales-Cruz, Ariel ⁷, Koomen, John M. ⁸, Atkins, Reginald M. ², Hansen, Doris K. ¹, S. Silva, Ariosto ⁹, Kim, Jongphil ¹⁰, Balagurunathan, Yoganand ¹¹, Locke, Frederick L. ¹

Source: In Blood October 2024

Clinical outcomes after idecabtagene vicleucel in older patients with multiple myeloma: a multicenter real-world experience

Authors: Kalariya, Nilesh M., Hildebrandt, Michelle A. T., Hansen, Doris K., Sidana, Surbhi, Khouri, Jack, Ferreri, Christopher J., Doyle, William N., Castaneda-Puglianini, Omar, Freeman, Ciara L., Hovanky, Vanna, Hosoya, Hitomi, Shune, Leyla O., Patel, Krina K.

Source: In Blood Advances 10 September 2024 8(17):4679-4688

Management of bone disease with concurrent chimeric antigen receptor T-cell therapy for multiple myeloma

Authors: Kuruvilla, Davis, Huynh, Thien, Nester, Matthew, Chose, Chloe, Zervoudakis, Guston, Letson, G.Douglas, Joyce, David M., Binitie, Odion T., Figura, Nicholas B., Costello, James R., Freeman, Ciara L., Lazarides, Alexander L.

Source: In Critical Reviews in Oncology / Hematology September 2024 201

Racial and ethnic differences in clinical outcomes among patients with multiple myeloma treated with CAR T-cell therapy

Authors: Peres, Lauren C., Oswald, Laura B., Dillard, Christen M., De Avila, Gabriel, Nishihori, Taiga, Blue, Brandon J., Freeman, Ciara L., Locke, Frederick L., Alsina, Melissa, Castaneda Puglianini, Omar, Shune, Leyla, Sborov, Douglas W., Wagner, Charlotte, Dima, Danai, Hashmi, Hamza, Davis, James A., Kocoglu, Mehmet H., Badros, Ashraf Z., Atrash, Shebli, Simmons, Gary, Kalariya, Nilesh, Ferreri, Christopher, Anderson, Larry D., Jr, Afrough, Aimaz, Kaur, Gurbakhash, Lin, Yi, Liu, Lawrence, Nadeem, Omar, Voorhees, Peter, Khouri, Jack, McGuirk, Joseph, Sidana, Surbhi, Hansen, Doris K., Patel, Krina

Source: In Blood Advances 9 January 2024 8(1):251-259

Molecular determinants of clinical outcomes in a real-world diffuse large B-cell lymphoma population

Authors: Alduaij, Waleed, Collinge, Brett, Ben-Neriah, Susana, Jiang, Aixiang, Hilton, Laura K., Boyle, Merrill, Meissner, Barbara, Chong, Lauren, Miyata-Takata, Tomoko, Slack, Graham W., Farinha, Pedro, Craig, Jeffrey W., Lytle, Andrew, Savage, Kerry J., Villa, Diego, Gerrie, Alina S., Freeman, Ciara L., Gascoyne, Randy D., Connors, Joseph M., Morin, Ryan D., Sehn, Laurie H., Mungall, Andrew J., Steidl, Christian, Scott, David W. ^∗

Source: In Blood 18 May 2023 141(20):2493-2507

Utilizing 3D Models to Unravel the Dynamics of Myeloma Plasma Cells' Escape from the Bone Marrow Microenvironment.

Authors: Verbruggen, Stefaan W.^1,2,3 (AUTHOR) s.verbruggen@qmul.ac.uk, Freeman, Ciara L.⁴ (AUTHOR) ciara.freeman@moffitt.org, Freeman, Fiona E.^5,6,7,8,9 (AUTHOR) s.verbruggen@qmul.ac.uk

Source: Cancers. Mar2024, Vol. 16 Issue 5, p889. 19p.

Subject Terms: *STRUCTURAL models, *CANCER relapse, *LIFE expectancy, *CANCER patients, *CELL lines, *EXTRAMEDULLARY diseases

Geographic Terms: UNITED Kingdom

Early cytopenias and infections after standard of care idecabtagene vicleucel in relapsed or refractory multiple myeloma

Authors: Logue, Jennifer M., Peres, Lauren C., Hashmi, Hamza, Colin-Leitzinger, Christelle M., Shrewsbury, Alexandria M., Hosoya, Hitomi, Gonzalez, Rebecca M., Copponex, Christina, Kottra, Krista H., Hovanky, Vanna, Sahaf, Bita, Patil, Sunita, Lazaryan, Aleksandr, Jain, Michael D., Baluch, Aliyah, Klinkova, Olga V., Bejanyan, Nelli, Faramand, Rawan G., Elmariah, Hany, Khimani, Farhad, Davila, Marco L., Mishra, Asmita, Blue, Brandon J., Grajales-Cruz, Ariel F., Castaneda Puglianini, Omar A., Liu, Hien D., Nishihori, Taiga, Freeman, Ciara L., Brayer, Jason B., Shain, Kenneth H., Baz, Rachid C., Locke, Frederick L., Alsina, Melissa, Sidana, Surbhi ^∗∗, Hansen, Doris K. ^∗

Source: In Blood Advances 27 December 2022 6(24):6109-6119

The outcome of older adults with classic Hodgkin lymphoma in British Columbia

Authors: Cheng, Phoebe T. M., Villa, Diego, Gerrie, Alina S., Freeman, Ciara L., Slack, Graham W., Gascoyne, Randy D., Farinha, Pedro, Craig, Jeffrey W., Skinnider, Brian, Wilson, Don, Scott, David W., Connors, Joseph M., Sehn, Laurie H., Savage, Kerry J.

Source: In Blood Advances 22 November 2022 6(22):5924-5932

Bendamustine or high-dose cytarabine-based induction with rituximab in transplant-eligible mantle cell lymphoma

Authors: Villa, Diego ^{*, *}, Hoster, Eva ^*, Hermine, Olivier, Klapper, Wolfram, Szymczyk, Michal, Bosly, André, Unterhalt, Michael, Rimsza, Lisa M., Ramsower, Colleen A., Freeman, Ciara L., Scott, David W., Gerrie, Alina S., Savage, Kerry J., Sehn, Laurie H., Dreyling, Martin

Source: In Blood Advances 27 September 2022 6(18):5285-5294

Outcomes after initial refusal of curative treatment in patients with classic Hodgkin lymphoma

Authors: Chahal, Manik, Hayden, Anna, Savage, Kerry J., Villa, Diego, Scott, David W., Gerrie, Alina S., Lo, Andrea, Chan, Matthew, Pickles, Tom, Connors, Joseph M., Sehn, Laurie Helen, Freeman, Ciara L.

Source: Leukemia & lymphoma. 63(11):2739-2742

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192736811.0x000001&indx=1&recIds=ETOCvdc_100192736811.0x000001

Clinicopathological characteristics and long‐term outcomes of plasmablastic lymphoma in British Columbia

Authors: Jessa, Rehan, Chien, Nicole, Villa, Diego, Freeman, Ciara L., Slack, Graham W., Savage, Kerry J., Scott, David W., Sehn, Laurie H., Song, Kevin W., Gerrie, Alina S.

Source: British journal of haematology. 199(2):230-238

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165265762.0x000001&indx=1&recIds=ETOCvdc_100165265762.0x000001

Outcomes of Hodgkin variant Richter transformation in chronic lymphocytic leukaemia and small lymphocytic lymphoma in British Columbia

Authors: Zhu, Kai, Jamroz, Andrew, Huang, Steven, Villa, Diego, Freeman, Ciara L., Scott, David W., Slack, Graham, Sehn, Laurie H., Connors, Joseph M., Toze, Cynthia L., Savage, Kerry J., Gerrie, Alina S.

Source: British journal of haematology. 198(4):684-692

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157747899.0x000001&indx=1&recIds=ETOCvdc_100157747899.0x000001

Outcome of limited-stage nodular lymphocyte-predominant Hodgkin lymphoma and the impact of a PET-adapted approach

Authors: Cheng, Phoebe T.M., Villa, Diego, Tonseth, R. Petter, Scott, David W., Gerrie, Alina S., Freeman, Ciara L., Pickles, Tom, Lo, Andrea C., Farinha, Pedro, Craig, Jeffrey W., Slack, Graham W., Gascoyne, Randy D., Bénard, François, Wilson, Don, Skinnider, Brian, Connors, Joseph M., Sehn, Laurie H., Savage, Kerry J. ^*

Source: In Blood Advances 28 September 2021 5(18):3647-3655

CNS relapse in high-grade B-cell lymphoma with MYCand BCL2rearrangements and dark-zone signature–expressing DLBCL

Authors: Alduaij, Waleed, Jiang, Aixiang, Villa, Diego, Collinge, Brett, Ben-Neriah, Susana, Boyle, Merrill, Meissner, Barbara, Hilton, Laura K., Farinha, Pedro, Slack, Graham W., Craig, Jeffrey W., Gerrie, Alina S., Freeman, Ciara L., Mungall, Andrew J., Steidl, Christian, Sehn, Laurie H., Scott, David W., Savage, Kerry J.

Source: Blood; February 2025, Vol. 145 Issue: 6 p590-596, 7p

Simple Score of Albumin and CRP Predicts High-Grade Toxicity in Patients with Multiple Myeloma Receiving CAR-T Therapy

Authors: Akhtar, Othman S., Modi, Karnav, Kim, Jongphil, Skelson, Lawrence, Smith, Eric, Al-Jumayli, Mohammed A., Extermann, Martine, De Avila, Gabriel, Parker, Nathan, Castaneda Puglianini, Omar, Grajales Cruz, Ariel, Baz, Rachid, Blue, Brandon, Shain, Kenneth, Alsina, Melissa, Liu, Hien, Nishihori, Taiga, Jain, Michael D., Locke, Frederick L., Hansen, Doris K., Freeman, Ciara L.

Source: In Transplantation and Cellular Therapy March 2024 30(3):283-283

Long-term results of PET-guided radiation in patients with advanced-stage diffuse large B-cell lymphoma treated with R-CHOP

Authors: Freeman, Ciara L., Savage, Kerry J., Villa, Diego R., Scott, David W., Srour, Line, Gerrie, Alina S., Brown, Maura J., Slack, Graham W., Farinha, Pedro, Skinnider, Brian, Morris, James, Bénard, François, Aquino-Parsons, Christina, Lo, Andrea, Pickles, Tom, Wilson, Don C., Tonseth, Petter, Connors, Joseph M., Sehn, Laurie H.

Source: Blood. 137(7):929-938

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183225613.0x000001&indx=1&recIds=ETOCvdc_100183225613.0x000001

Outcome of primary mediastinal large B-cell lymphoma using R-CHOP: impact of a PET-adapted approach

Authors: Hayden, Anna R., Tonseth, Petter, Lee, Derrick G., Villa, Diego, Gerrie, Alina S., Scott, David W., Freeman, Ciara L., Slack, Graham W., Farinha, Pedro, Skinnider, Brian, Yenson, Paul R., Benard, Francois, Lo, Andrea, Pickles, Tom, Wilson, Donald, Connors, Joseph M., Sehn, Laurie H., Savage, Kerry J. ^*

Source: In Blood 10 December 2020 136(24):2803-2811

Bendamustine and rituximab as induction therapy in both transplant-eligible and -ineligible patients with mantle cell lymphoma

Authors: Villa, Diego ^*, Sehn, Laurie H., Savage, Kerry J., Toze, Cynthia L., Song, Kevin, den Brok, Wendie D., Freeman, Ciara L., Scott, David W., Gerrie, Alina S.

Source: In Blood Advances 11 August 2020 4(15):3486-3494

Initial Treatment of High Tumor Burden Follicular Lymphoma

Authors: Freeman, Ciara L., Sehn, Laurie H.

Source: In Hematology/Oncology Clinics of North America August 2020 34(4):673-687