Differences between bone health parameters in adults with acromegaly and growth hormone deficiency: A systematic review

Authors: Freda, Pamela U.

Source: In Best Practice & Research Clinical Endocrinology & Metabolism December 2023 37(6)

Acromegaly: diagnostic challenges and individualized treatment.

Authors: Freda, Pamela U.

Source: Expert Review of Endocrinology & Metabolism; Jan2025, Vol. 20 Issue 1, p63-85, 23p

Subject Terms: MEDICAL personnel, SOMATOSTATIN receptors, PITUITARY tumors, ACROMEGALY, SYMPTOMS

Gonadotroph tumours with a low SF‐1 labelling index are more likely to recur and are associated with enrichment of the PI3K‐AKT pathway

Authors: Hickman, Richard A., Bruce, Jeffrey N., Otten, Marc, Khandji, Alexander G., Flowers, Xena E., Siegelin, Markus, Lopes, Beatriz, Faust, Phyllis L., Freda, Pamela U.

Source: Neuropathology & applied neurobiology. 47(3):415-427

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116963537.0x000001&indx=1&recIds=ETOCvdc_100116963537.0x000001

Impact of medical therapy for hormone-secreting Pituitary tumors on bone.

Authors: Freda, Pamela U.

Source: Pituitary; Dec2024, Vol. 27 Issue 6, p860-873, 14p

A Pituitary Society update to acromegaly management guidelines

Authors: Fleseriu, Maria, Biller, Beverly M. K., Freda, Pamela U., Gadelha, Monica R., Giustina, Andrea, Katznelson, Laurence, Molitch, Mark E., Samson, Susan L., Strasburger, Christian J., van der Lely, A. J., Melmed, Shlomo

Source: PITUITARY -DORDRECHT. 24(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194175911.0x000001&indx=1&recIds=ETOCvdc_100194175911.0x000001

Multidisciplinary management of acromegaly: A consensus

Authors: Giustina, Andrea, Barkhoudarian, Garni, Beckers, Albert, Ben-Shlomo, Anat, Biermasz, Nienke, Biller, Beverly, Boguszewski, Cesar, Bolanowski, Marek, Bollerslev, Jens, Bonert, Vivien, Bronstein, Marcello D., Buchfelder, Michael, Casanueva, Felipe, Chanson, Philippe, Clemmons, David, Fleseriu, Maria, Formenti, Anna Maria, Freda, Pamela, Gadelha, Monica, Geer, Eliza, Gurnell, Mark, Heaney, Anthony P., Ho, Ken K. Y., Ioachimescu, Adriana G., Lamberts, Steven, Laws, Edward, Losa, Marco, Maffei, Pietro, Mamelak, Adam, Mercado, Moises, Molitch, Mark, Mortini, Pietro, Pereira, Alberto M., Petersenn, Stephan, Post, Kalmon, Puig-Domingo, Manuel, Salvatori, Roberto, Samson, Susan L., Shimon, Ilan, Strasburger, Christian, Swearingen, Brooke, Trainer, Peter, Vance, Mary L., Wass, John, Wierman, Margaret E., Yuen, Kevin C. J., Zatelli, Maria Chiara, Melmed, Shlomo

Source: Reviews in endocrine and metabolic disorders. 21(4):667-678

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171593308.0x000001&indx=1&recIds=ETOCvdc_100171593308.0x000001

Long-term Pegvisomant Therapy of Acromegaly: Effects on Bone Density, Turnover and Microstructure Using HRpQCT.

Authors: Kuker, Adriana P, Agarwal, Sanchita, Shane, Elizabeth, Bicca, Juliana, Geer, Eliza B, Cremers, Serge, Dworakowski, Elzbieta, Cohen, Adi, Nickolas, Thomas L, Stein, Emily M, Freda, Pamela U

Source: Journal of the Endocrine Society; Jun2024, Vol. 8 Issue 6, p1-13, 13p

Subject Terms: ACROMEGALY, LUMBAR vertebrae, BONE density, DUAL-energy X-ray absorptiometry, BONE remodeling, COMPUTED tomography, MICROSTRUCTURE

Outcome Of Implementation Of A Multidisciplinary Team Approach To The Care Of Patients After Transsphenoidal Surgery

Authors: Carminucci, Arthur S., Ausiello, John C., Page-Wilson, Gabrielle, Lee, Michelle, Good, Laura, Bruce, Jeffrey N., Freda, Pamela U. ^*

Source: In Endocrine Practice January 2016 22(1):36-44

Long-Term Treatment with Pegvisomant as Monotherapy in Patients with Acromegaly: Experience from Acrostudy

Authors: Freda, Pamela U. ^*, Gordon, Murray B., Nicky Kelepouris, Jonsson, Peter, Koltowska-Haggstrom, Maria, van der Lely, A.J.

Source: In Endocrine Practice March 2015 21(3):264-274

Persistent Deficits in Bone Quality in Treated Acromegaly: Evidence From Assessments of Microstructure.

Authors: Kuker, Adriana P, Agarwal, Sanchita, Shane, Elizabeth, Cohen, Adi, Nickolas, Thomas L, Stein, Emily M, Reid, Tirissa J, Hans, Didier, Cremers, Serge, Bruce, Jeffrey N, Freda, Pamela U

Source: Journal of the Endocrine Society; Oct2023, Vol. 7 Issue 10, p1-17, 17p

Subject Terms: DUAL-energy X-ray absorptiometry, ACROMEGALY, LUMBAR vertebrae, BONE density, CANCELLOUS bone

Adipose Tissue Redistribution and Ectopic Lipid Deposition in Active Acromegaly and Effects of Surgical Treatment

Authors: Reyes-Vidal, Carlos M., Mojahed, Hamed, Shen, Wei, Jin, Zhezhen, Arias-Mendoza, Fernando, Fernandez, Jean Carlos, Gallagher, Dympna, Bruce, Jeffrey N., Post, Kalmon D., Freda, Pamela U.

Source: Journal of clinical endocrinology and metabolism. 100(8):2946-2955

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN602358200&indx=1&recIds=ETOCRN602358200

Long-term Outcome of Body Composition, Ectopic Lipid, and Insulin Resistance Changes With Surgical Treatment of Acromegaly.

Authors: Kuker, Adriana P, Shen, Wei, Jin, Zhezhen, Chen, Jun, Bruce, Jeffrey N, Freda, Pamela U

Source: Journal of the Endocrine Society; May2023, Vol. 7 Issue 5, p1-13, 13p

Subject Terms: ACROMEGALY, GLUCOSE tolerance tests, GLUCOSE clamp technique, BODY composition, INSULIN resistance, METABOLIC syndrome, TYPE 2 diabetes, SOMATOMEDIN C

#1705024 A Randomized Phase 3 Trial to Assess Efficacy and Safety of a Novel Formulation of Octreotide Subcutaneous Depot (CAM2029) in Patients With Acromegaly

Authors: Silverstein, Julie, Ferone, Diego, Freda, Pamela, Katznelson, Laurence, Gatto, Federico, Kadioglu, Pinar, Maffei, Pietro, Seufert, Jochen, Spencer-Segal, Joanna L., Isaeva, Elena, Dreval, Alexander, Harrie, Maria, Svedberg, Agneta, Tiberg, Fredrik

Source: In Endocrine Practice May 2024 30(5) Supplement:S117-S118

Measurement of human growth hormone by immunoassays: Current status, unsolved problems and clinical consequences

Authors: Bidlingmaier, Martin, Freda, Pamela U.

Source: In Growth Hormone & IGF Research 2010 20(1):19-25

The current status of IGF-I assays – A 2009 update

Authors: Frystyk, Jan, Freda, Pamela, Clemmons, David R.

Source: In Growth Hormone & IGF Research 2010 20(1):8-18

The acromegaly lipodystrophy.

Authors: Freda, Pamela U.

Source: Frontiers in Endocrinology; 9/13/2022, Vol. 13, p1-12, 12p

Subject Terms: ACROMEGALY, SOMATOMEDIN C, LIPODYSTROPHY, BODY composition, ADIPOSE tissues

How effective are current therapies for acromegaly?

Authors: Freda, Pamela U

Source: In Growth Hormone & IGF Research 2003 13 Supplement:S144-S151

Current concepts in the biochemical assessment of the patient with acromegaly

Authors: Freda, Pamela U.

Source: In Growth Hormone & IGF Research 2003 13(4):171-184

Acylation of ghrelin is increased in heart failure and decreases post heart transplantation.

Authors: Zabarovskaja, Stanislava¹ (AUTHOR) stanislava.zabarovskaja@ki.se, Freda, Pamela² (AUTHOR), Williams, Jill J.² (AUTHOR), Kunavarapu, Chandra² (AUTHOR), Lamanca, John² (AUTHOR), Mancini, Donna² (AUTHOR), Lund, Lars H.¹ (AUTHOR)

Source: Scandinavian Cardiovascular Journal. Dec2014, Vol. 48 Issue 6, p343-348. 6p.

Subject Terms: *HEART transplantation, *APPETITE stimulants, *BODY mass index, *GHRELIN receptors, *HEART failure, *ACYLATION

Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist

Authors: van der Lely, Aart Jan, Hutson, R Kent, Trainer, Peter J, Besser, G Michael, Barkan, Ariel L, Katznelson, Laurence, Klibanski, Anne, Herman-Bonert, Vivien, Melmed, Shlomo, Vance, Mary Lee, Freda, Pamela U, Stewart, Paul M, Friend, Keith E, Clemmons, David R, Johannsson, Gudmundur, Stavrou, Stavros, Cook, David M, Phillips, Lawrence S, Strasburger, Christian J, Hacker, Suzanne, Zib, Kenneth A, Davis, Robert J, Scarlett, John A, Thorner, Michael O

Source: In The Lancet 2001 358(9295):1754-1759