Protocol for the San Diego Nathan Shock Center Clinical Cohort: a new resource for studies of human aging

Authors: Jeanne F Nichols, Ryan Moran, Howard J Phang, Stephanie R Heimler, Lina M Scandalis, David Wing, Daniel Moreno, Gerald S Shadel, Fred H Gage, Anthony J A Molina

Source: BMJ Open, Vol 14, Iss 6 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/14/6/e082659.full; https://doaj.org/toc/2044-6055

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AAV ablates neurogenesis in the adult murine hippocampus

Authors: Stephen Johnston, Sarah L Parylak, Stacy Kim, Nolan Mac, Christina Lim, Iryna Gallina, Cooper Bloyd, Alexander Newberry, Christian D Saavedra, Ondrej Novak, J Tiago Gonçalves, Fred H Gage, Matthew Shtrahman

Source: eLife, Vol 10 (2021)

Subject Terms: hippocampus, dentate gyrus, adult neurogenesis, adeno-associated virus (AAV), neural progenitor cell, gene therapy, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/59291; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/d6ed94cb81614f08ad343b6ed27bc2a8

Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons

Authors: Joseph Herdy, Simon Schafer, Yongsung Kim, Zoya Ansari, Dina Zangwill, Manching Ku, Apua Paquola, Hyungjun Lee, Jerome Mertens, Fred H Gage

Source: eLife, Vol 8 (2019)

Subject Terms: direct reprogramming, iN, transgenesis, pathway analysis, lentivirus, induced neurons, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/41356; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/3e403c8aedd14108b8fe7d58a335b439

Species-specific maturation profiles of human, chimpanzee and bonobo neural cells

Authors: Maria C Marchetto, Branka Hrvoj-Mihic, Bilal E Kerman, Diana X Yu, Krishna C Vadodaria, Sara B Linker, Iñigo Narvaiza, Renata Santos, Ahmet M Denli, Ana PD Mendes, Ruth Oefner, Jonathan Cook, Lauren McHenry, Jaeson M Grasmick, Kelly Heard, Callie Fredlender, Lynne Randolph-Moore, Rijul Kshirsagar, Rea Xenitopoulos, Grace Chou, Nasun Hah, Alysson R Muotri, Krishnan Padmanabhan, Katerina Semendeferi, Fred H Gage

Source: eLife, Vol 8 (2019)

Subject Terms: neurodevelopment, neuronal function, chimpanzee, non human primate, neuroprogenitor migration, evolution, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/37527; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/8eb5b01f74684625be3abe311de8e7dd

Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

Authors: Xinde Zheng, Leah Boyer, Mingji Jin, Jerome Mertens, Yongsung Kim, Li Ma, Michael Hamm, Fred H Gage, Tony Hunter

Source: eLife, Vol 5 (2016)

Subject Terms: glycolysis, neuronal differentiation, stem cell, LDHA, metabolism, tricarboxylic acid cycle, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/13374; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/221dfd8b30b24e6cb42a4ace07578e2c

Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration

Authors: Xinde Zheng, Leah Boyer, Mingji Jin, Yongsung Kim, Weiwei Fan, Cedric Bardy, Travis Berggren, Ronald M Evans, Fred H Gage, Tony Hunter

Source: eLife, Vol 5 (2016)

Subject Terms: mitochondria, rapamycin, ATP, iPS disease modeling, maternally inherited Leigh syndrome, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/13378; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/33701fc01b264587a4c9be099cc54e22

Alternative splicing events identified in human embryonic stem cells and neural progenitors.

Authors: Gene W Yeo, Xiangdong Xu, Tiffany Y Liang, Alysson R Muotri, Christian T Carson, Nicole G Coufal, Fred H Gage

Source: PLoS Computational Biology, Vol 3, Iss 10, Pp 1951-1967 (2007)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2041973?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/24b182a2e8a24c499670e239a31ce42c

Distinct roles of NMDA receptors at different stages of granule cell development in the adult brain

Authors: Yangling Mu, Chunmei Zhao, Nicolas Toni, Jun Yao, Fred H Gage

Source: eLife, Vol 4 (2015)

Subject Terms: NMDA receptor, adult neurogenesis, spine, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/07871; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/84ab518fc05149c6bf17ad4e79a60b2f

The effect of immature adult-born dentate granule cells on hyponeophagial behavior is related to their roles in learning and memory

Authors: Wei eDeng, Fred H Gage

Source: Frontiers in Systems Neuroscience, Vol 9 (2015)

Subject Terms: Anxiety, Depression, Hippocampus, adult neurogenesis, learning and memory, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fnsys.2015.00034/full; https://doaj.org/toc/1662-5137

Access URL: https://doaj.org/article/2d821ad9c277480cb9fb447b4d752f3e

A Hypothesis for Temporal Coding of Young and Mature Granule Cells

Authors: Lara M Rangel, Laleh K Quinn, Andrea A Chiba, Fred H Gage, James B Aimone

Source: Frontiers in Neuroscience, Vol 7 (2013)

Subject Terms: Dentate Gyrus, Hippocampus, adult neurogenesis, oscillations, temporal coding, granule cells, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00075/full; https://doaj.org/toc/1662-453X

Access URL: https://doaj.org/article/a0d3efe0b5a84121b9e4fb6cee55ee4f

Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice

Authors: Wei Deng, Mark Mayford, Fred H Gage

Source: eLife, Vol 2 (2013)

Subject Terms: learning and memory, dentate gyrus, pattern separation, CA1, hippocampus, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/00312; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/3627377480ff4ffaa99634a45700d8a7

Dynamic association of NUP98 with the human genome.

Authors: Yun Liang, Tobias M Franks, Maria C Marchetto, Fred H Gage, Martin W Hetzer

Source: PLoS Genetics, Vol 9, Iss 2, p e1003308 (2013)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3585015?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/3a722c79f1cc45af9d0c92b698400662

P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury.

Authors: Tsung-Chang Sung, Zhijiang Chen, Sandrine Thuret, Marçal Vilar, Fred H Gage, Roland Riek, Kuo-Fen Lee

Source: PLoS ONE, Vol 8, Iss 7, p e69286 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3720591?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/892cb4cac9974abdb6bb42f526d6949d

Enhanced functional recovery in MRL/MpJ mice after spinal cord dorsal hemisection.

Authors: Sandrine Thuret, Michaela Thallmair, Laura L Horky, Fred H Gage

Source: PLoS ONE, Vol 7, Iss 2, p e30904 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3278405?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cb3d2eb538934a83bf45ba51013abae5

Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells.

Authors: Shauna H Yuan, Jody Martin, Jeanne Elia, Jessica Flippin, Rosanto I Paramban, Mike P Hefferan, Jason G Vidal, Yangling Mu, Rhiannon L Killian, Mason A Israel, Nil Emre, Silvia Marsala, Martin Marsala, Fred H Gage, Lawrence S B Goldstein, Christian T Carson

Source: PLoS ONE, Vol 6, Iss 3, p e17540 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3047583?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b56b0088093f4d5f81634553f591aa8c

High-efficient generation of induced pluripotent stem cells from human astrocytes.

Authors: Sergio Ruiz, Kristen Brennand, Athanasia D Panopoulos, Aída Herrerías, Fred H Gage, Juan Carlos Izpisua-Belmonte

Source: PLoS ONE, Vol 5, Iss 12, p e15526 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3000364?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b14a7f3c77e943c9974d14cc5914f1fc

Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource

Authors: Rupert W Overall, Gerd Kempermann, Jeremy Peirce, Lu Lu, Dan Goldowitz, Fred H Gage, Shirlean Goodwin, August B Smit, David C Airey, Glenn D Rosen, Leonard C Schalkwyk, Thomas R Sutter, Richard S. Nowakowski, Stephen Whatley, Robert W Williams

Source: Frontiers in Neuroscience, Vol 3 (2009)

Subject Terms: Hippocampus, QTL, Genetical Genomics, recombinant inbred mice, transcript expression, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/neuro.15.003.2009/full; https://doaj.org/toc/1662-453X

Access URL: https://doaj.org/article/63fcd0ddcbaa412dbdaba773d2c7d34f

Transcriptional signature and memory retention of human-induced pluripotent stem cells.

Authors: Maria C N Marchetto, Gene W Yeo, Osamu Kainohana, Martin Marsala, Fred H Gage, Alysson R Muotri

Source: PLoS ONE, Vol 4, Iss 9, p e7076 (2009)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2741600?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/76bad8f8eba74af398bf1179d85e48ba

Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus.

Authors: Sebastian Jessberger, Stefan Aigner, Gregory D Clemenson, Nicolas Toni, D Chichung Lie, Ozlem Karalay, Rupert Overall, Gerd Kempermann, Fred H Gage

Source: PLoS Biology, Vol 6, Iss 11, p e272 (2008)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18998770/pdf/?tool=EBI; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/06afef277800419ebaecaa42dfeeb63b

Functional convergence of neurons generated in the developing and adult hippocampus.

Authors: Diego A Laplagne, M Soledad Espósito, Verónica C Piatti, Nicolás A Morgenstern, Chunmei Zhao, Henriette van Praag, Fred H Gage, Alejandro F Schinder

Source: PLoS Biology, Vol 4, Iss 12, p e409 (2006)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/3f43b9212b3445f8b0784242a8c651f2