Decompensated MASH-Cirrhosis Model by Acute and Toxic Effects of Phenobarbital

Authors: Nico Kraus, Frank Erhard Uschner, Magnus Moeslein, Robert Schierwagen, Wenyi Gu, Maximilian Joseph Brol, Eike Fürst, Inga Grünewald, Sophie Lotersztajn, Pierre-Emmanuel Rautou, Marta Duran-Güell, Roger Flores Costa, Joan Clària, Jonel Trebicka, Sabine Klein

Source: Cells, Vol 13, Iss 20, p 1707 (2024)

Subject Terms: metabolic dysfunction-associated steatohepatitis (MASH), carbon tetrachloride (CCl4), high-fat and high-cholesterol Western diet (WD), phenobarbital (PB), long-term (LT), short-term (ST), Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/20/1707; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/a6c4dc46329743e4a0b6a44027d7501d

Personalised human albumin in patients with cirrhosis and ascites: design and rationale for the ALB-TRIAL - a randomised clinical biomarker validation trial

Authors: Torben Hansen, Pere Ginès, Wim Laleman, Peer Bork, Vishal C Patel, Debbie Shawcross, Robert Schierwagen, Camila Alvarez-Silva, Florence Servant, Jonel Trebicka, Benjamin Lelouvier, Manimozhiyan Arumugam, Ed J Kuijper, Frank Erhard Uschner, Michael Praktiknjo, Mária Papp, Saeed Shoaie, Michael Kühn, Maja Thiele, Paolo Angeli, Joan Claria, Vicente Arroyo, Manolo Laiola, Benoit Quinquis, Sabine Klein, Minneke J Coenraad, François Fenaille, Debbie Lindsay Shawcross, Wenyi Gu, Adria Juanola, Elisa Pose, Aleksander Krag, Ivica Letunic, Alain Pruvost, Hervé M Blottière, Nathalie Galleron, Cristina López-Vicario, Peter V Treit, Matthias Mann, Jelle Matthijnssens, Mark J W Mcphail, Philipp E Geyer, Hans Olav Melberg, Stefanie Kandels, Cristina Sánchez-Garrido, Florence A Castelli, Christophe Junot, Lars Asphaug, Mads Israelsen, Helene Bæk Juel, Nikolaj Torp, Minneke Coenraad, Marko Korenjak, Ferran Aguilar-Parera, Patricia Sierra-Casas, Anna Bosch-Comas, David Tornai, Boglarka Balogh, Katrine Holtz Thorhauge, Casper Sahl Poulsen, Thea Van Rossum, Suguru Nishijima, Marisa I Keller, Diënty H M Hazenbrink, Sylvain Dechaumet, Sebastian D Burz, Emeline Chu-Van, Etienne Thévenot, Florian A Rosenberger, Sebastian Van Blerk, Amirouche Ouzerdine, Alain Roulet, Jean-Louis-Marie Insonere, Céline Serres, Mathieu Almeida, Florence Thirion, Camille Champion, Chaima Ezzine, Célia Chamignon, Nicolas Lapaque, Mamadou Gabou Thiam, Lore Van Espen, Quinten R Ducarmon, Annelotte GC Broekhoven, Susan Fischer, Romy Zwittink, Itziar De Lecuona, Giulio Rosati, Celia Fuentes-Chust, Arben Merkoçi, Massimo Urban, José Alfonso Marrugo-Ramirez, Ameli Schwalber, Lindsey Ann Edwards, Victoria Tatiana Kronsten, David Moyes, Azadeh Harzandi, Jordi Gratacós-Ginès, Martina Pérez-Guasch, Miriam Pellón, Bryan Contreras, Max Brol, Manfred Fobker, Renata Antonina Feuerborn

Source: BMJ Open, Vol 14, Iss 2 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/14/2/e079309.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/289f12a27d2047adb5cb758cb2809703

Myostatin is associated with the presence and development of acute-on-chronic liver failure

Authors: Astrid Ruiz-Margáin, Alessandra Pohlmann, Silke Lanzerath, Melanie Langheinrich, Alejandro Campos-Murguía, Berenice M. Román-Calleja, Robert Schierwagen, Sabine Klein, Frank Erhard Uschner, Maximilian Joseph Brol, Aldo Torre-Delgadillo, Nayelli C. Flores-García, Michael Praktiknjo, Ricardo U. Macías Rodríguez, Jonel Trebicka

Source: JHEP Reports, Vol 5, Iss 8, Pp 100761- (2023)

Subject Terms: myostatin, malnutrition, sarcopenia, ACLF, cirrhosis, liver failure, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923000927; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/2b92ac9275db4bf3b41edd5f918142df

Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis.

Authors: Alexander Queck, Dominique Thomas, Christian Jansen, Yannick Schreiber, Sabrina Rüschenbaum, Michael Praktiknjo, Katharina Maria Schwarzkopf, Marcus Maximilian Mücke, Robert Schierwagen, Frank Erhard Uschner, Carsten Meyer, Joan Clària, Stefan Zeuzem, Gerd Geisslinger, Jonel Trebicka, Christian Markus Lange

Source: PLoS ONE, Vol 14, Iss 10, p e0222840 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d522e264dc63433d807dcfdd0d4ee556

Novel Rat Model of Repetitive Portal Venous Embolization Mimicking Human Non-Cirrhotic Idiopathic Portal Hypertension.

Authors: Sabine Klein, Christian Hinüber, Kanishka Hittatiya, Robert Schierwagen, Frank Erhard Uschner, Christian P Strassburg, Hans-Peter Fischer, Ulrich Spengler, Jonel Trebicka

Source: PLoS ONE, Vol 11, Iss 9, p e0162144 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5010239?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/949619ea25314c0196cd35dd1710c450

Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis.

Authors: Jan eGörtzen, Robert eSchierwagen, Jeanette eBierwolf, Sabine eKlein, Frank Erhard Uschner, Peter F. van der Ven, Dieter O. Fürst, Christian P. Strassburg, Wim eLaleman, Jörg-Matthias ePollok, Jonel eTrebicka

Source: Frontiers in Physiology, Vol 6 (2015)

Subject Terms: Hepatic Stellate Cells, RhoA, src, liver fibrosis, PP2, Matrix stiffness, Physiology, QP1-981

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00359/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/3caf4cf4e3ff47f596df6e57cbff4ad2