Molecular mechanism of IKK catalytic dimer docking to NF-κB substrates

Authors: Changqing Li, Stefano Moro, Kateryna Shostak, Francis J. O’Reilly, Mariel Donzeau, Andrea Graziadei, Alastair G. McEwen, Dominique Desplancq, Pierre Poussin-Courmontagne, Thomas Bachelart, Mert Fiskin, Nicolas Berrodier, Simon Pichard, Karl Brillet, Georges Orfanoudakis, Arnaud Poterszman, Vladimir Torbeev, Juri Rappsilber, Norman E. Davey, Alain Chariot, Katia Zanier

Source: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7002b32fa22e4bd38f05d9ec9d049537

Structural analysis of an endogenous 4-megadalton succinyl-CoA-generating metabolon

Authors: Ioannis Skalidis, Fotis L. Kyrilis, Christian Tüting, Farzad Hamdi, Toni K. Träger, Jaydeep Belapure, Gerd Hause, Marta Fratini, Francis J. O’Reilly, Ingo Heilmann, Juri Rappsilber, Panagiotis L. Kastritis

Source: Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/35a1a0d0d41747198ab9194230348b40

Reliable identification of protein-protein interactions by crosslinking mass spectrometry

Authors: Swantje Lenz, Ludwig R. Sinn, Francis J. O’Reilly, Lutz Fischer, Fritz Wegner, Juri Rappsilber

Source: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/5e27def07ee34f139b97a8e8b802239b

Integrative structure of a 10-megadalton eukaryotic pyruvate dehydrogenase complex from native cell extracts

Authors: Fotis L. Kyrilis, Dmitry A. Semchonok, Ioannis Skalidis, Christian Tüting, Farzad Hamdi, Francis J. O’Reilly, Juri Rappsilber, Panagiotis L. Kastritis

Source: Cell Reports, Vol 34, Iss 6, Pp 108727- (2021)

Subject Terms: native cell extracts, cellular homogenates, keto acid dehydrogenase complexes, negative staining, cryo-EM, image processing, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124721000401; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/b6e1b450bfa348c58d6495404d4a485b

Protein complexes in cells by AI‐assisted structural proteomics

Authors: Francis J O'Reilly, Andrea Graziadei, Christian Forbrig, Rica Bremenkamp, Kristine Charles, Swantje Lenz, Christoph Elfmann, Lutz Fischer, Jörg Stülke, Juri Rappsilber

Source: Molecular Systems Biology, Vol 19, Iss 4, Pp 1-20 (2023)

Subject Terms: AlphaFold‐Multimer, crosslinking mass spectrometry, protein–protein interactions, pyruvate dehydrogenase, uncharacterized proteins, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/14683564958d4e7492255d7909574e7a

An integrated workflow for crosslinking mass spectrometry

Authors: Marta L Mendes, Lutz Fischer, Zhuo A Chen, Marta Barbon, Francis J O'Reilly, Sven H Giese, Michael Bohlke‐Schneider, Adam Belsom, Therese Dau, Colin W Combe, Martin Graham, Markus R Eisele, Wolfgang Baumeister, Christian Speck, Juri Rappsilber

Source: Molecular Systems Biology, Vol 15, Iss 9, Pp 1-13 (2019)

Subject Terms: crosslinking mass spectrometry, protein–protein interactions, proteomics, software, structural biology, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/dc2c1aa4ba3649908c7432cf24169792

Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.

Authors: Sofia Banchenko, Ferdinand Krupp, Christine Gotthold, Jörg Bürger, Andrea Graziadei, Francis J O'Reilly, Ludwig Sinn, Olga Ruda, Juri Rappsilber, Christian M T Spahn, Thorsten Mielke, Ian A Taylor, David Schwefel

Source: PLoS Pathogens, Vol 17, Iss 8, p e1009775 (2021)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/b63e6e33cdeb4efb8f380f91c2f56491

Coupling proteomics and metabolomics for the unsupervised identification of protein-metabolite interactions in Chaetomium thermophilum.

Authors: Yuanyue Li, Michael Kuhn, Joanna Zukowska-Kasprzyk, Marco L Hennrich, Panagiotis L Kastritis, Francis J O'Reilly, Prasad Phapale, Martin Beck, Anne-Claude Gavin, Peer Bork

Source: PLoS ONE, Vol 16, Iss 7, p e0254429 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0254429&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/96a7478f6dc84ecaaf836e81e344870f

Capturing protein communities by structural proteomics in a thermophilic eukaryote

Authors: Panagiotis L Kastritis, Francis J O'Reilly, Thomas Bock, Yuanyue Li, Matt Z Rogon, Katarzyna Buczak, Natalie Romanov, Matthew J Betts, Khanh Huy Bui, Wim J Hagen, Marco L Hennrich, Marie‐Therese Mackmull, Juri Rappsilber, Robert B Russell, Peer Bork, Martin Beck, Anne‐Claude Gavin

Source: Molecular Systems Biology, Vol 13, Iss 7, Pp 1-14 (2017)

Subject Terms: computational modeling, cryo‐electron microscopy, fatty acid synthase, interaction proteomics, metabolon, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/15f6ec5f9421498ca23ca26e8be3eb20

Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome‐reduced bacterium

Authors: Maria Lluch‐Senar, Javier Delgado, Wei‐Hua Chen, Verónica Lloréns‐Rico, Francis J O'Reilly, Judith AH Wodke, E Besray Unal, Eva Yus, Sira Martínez, Robert J Nichols, Tony Ferrar, Ana Vivancos, Arne Schmeisky, Jörg Stülke, Vera van Noort, Anne‐Claude Gavin, Peer Bork, Luis Serrano

Source: Molecular Systems Biology, Vol 11, Iss 1, Pp 1-7 (2015)

Subject Terms: minimal genome, non‐coding RNAs, small proteins, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/9799bb6ce59249468240a44d86279119