Multicohort Analysis Identifies Monocyte Gene Signatures to Accurately Monitor Subset-Specific Changes in Human Diseases

Authors: Francesco Vallania, Liron Zisman, Claudia Macaubas, Shu-Chen Hung, Narendiran Rajasekaran, Sonia Mason, Jonathan Graf, Mary Nakamura, Elizabeth D. Mellins, Purvesh Khatri

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: Systems Immunology, Gene signatures, monocyte subsets, gene expression, flow cytometry markers, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.659255/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/5e21d2668ecb4c8c939180ee83f3885e

Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases

Authors: Francesco Vallania, Andrew Tam, Shane Lofgren, Steven Schaffert, Tej D. Azad, Erika Bongen, Winston Haynes, Meia Alsup, Michael Alonso, Mark Davis, Edgar Engleman, Purvesh Khatri

Source: Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/6f12c79a854b4734a673942857dc8a8a

KLRD1-expressing natural killer cells predict influenza susceptibility

Authors: Erika Bongen, Francesco Vallania, Paul J. Utz, Purvesh Khatri

Source: Genome Medicine, Vol 10, Iss 1, Pp 1-12 (2018)

Subject Terms: Influenza, Natural killer cells, Hematopoietic stem and progenitor cells, KLRD1, CD94, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13073-018-0554-1; https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/792b91cb36e04b1eac9bb8c5302274ac

Interpretation of biological experiments changes with evolution of the Gene Ontology and its annotations

Authors: Aurelie Tomczak, Jonathan M. Mortensen, Rainer Winnenburg, Charles Liu, Dominique T. Alessi, Varsha Swamy, Francesco Vallania, Shane Lofgren, Winston Haynes, Nigam H. Shah, Mark A. Musen, Purvesh Khatri

Source: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/22ec44186f434485be70d5c0e2be2183

A 20-Gene Set Predictive of Progression to Severe Dengue

Authors: Makeda Robinson, Timothy E. Sweeney, Rina Barouch-Bentov, Malaya Kumar Sahoo, Larry Kalesinskas, Francesco Vallania, Ana Maria Sanz, Eliana Ortiz-Lasso, Ludwig Luis Albornoz, Fernando Rosso, Jose G. Montoya, Benjamin A. Pinsky, Purvesh Khatri, Shirit Einav

Source: Cell Reports, Vol 26, Iss 5, Pp 1104-1111.e4 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719300427; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/865568cfc5d248e58afab14afbaa10ff

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

Authors: Francesco Vallania, author¹, Enrique Ramos, author¹, Sharon Cresci, author², Robi D. Mitra, author¹, Todd E. Druley, author^{1, 3}

Source: Journal of Visualized Experiments. (64)

Availability: http://www.jove.com/video/3943

The RhoU/Wrch1 Rho GTPase gene is a common transcriptional target of both the gp130/STAT3 and Wnt-1 pathways.

Authors: Davide Schiavone, Sarah Dewilde, Francesco Vallania, James Turkson, Ferdinando Di Cunto, Valeria Poli

Source: Biochemical Journal; Jun2009, Vol. 421 Issue 2, p283-292, 10p

Subject Terms: GUANOSINE triphosphatase genes, GENETIC transcription, GENE targeting, TRANSCRIPTION factors, CYTOKINES, GROWTH factors, CELLULAR signal transduction, ONCOGENES