Renal amyloid‐A amyloidosis in cats: Characterization of proteinuria and biomarker discovery, and associations with kidney histology

Authors: Carlo Palizzotto, Filippo Ferri, Carolina Callegari, Francesco Rossi, Marcello Manfredi, Laura Carcangiu, Gabriele Gerardi, Silvia Ferro, Laura Cavicchioli, Elizabeth Müller, Marco Weiss, Anne‐Catherine Vogt, Francesca Lavatelli, Stefano Ricagno, Karyl Hurley, Eric Zini

Source: Journal of Veterinary Internal Medicine, Vol 38, Iss 1, Pp 205-215 (2024)

Subject Terms: chronic kidney disease, diagnosis, feline, fibrils, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/0891-6640; https://doaj.org/toc/1939-1676

Access URL: https://doaj.org/article/6b1be9a322184edf9cc3b6b664bf646c

Human wild‐type and D76N β2‐microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans

Authors: Sara Raimondi, Giulia Faravelli, Paola Nocerino, Valentina Mondani, Alma Baruffaldi, Loredana Marchese, Maria Chiara Mimmi, Diana Canetti, Guglielmo Verona, Marianna Caterino, Margherita Ruoppolo, P. Patrizia Mangione, Vittorio Bellotti, Francesca Lavatelli, Sofia Giorgetti

Source: FASEB BioAdvances, Vol 5, Iss 11, Pp 484-505 (2023)

Subject Terms: C. elegans, integrated omics, misfolding, proteotoxicity, systemic amyloidosis, β2‐microglobulin, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2573-9832

Access URL: https://doaj.org/article/5149cb901be64b8ea5200c5f776cb102

Cryo-EM structure of ex vivo fibrils associated with extreme AA amyloidosis prevalence in a cat shelter

Authors: Tim Schulte, Antonio Chaves-Sanjuan, Giulia Mazzini, Valentina Speranzini, Francesca Lavatelli, Filippo Ferri, Carlo Palizzotto, Maria Mazza, Paolo Milani, Mario Nuvolone, Anne-Cathrine Vogt, Monique Vogel, Giovanni Palladini, Giampaolo Merlini, Martino Bolognesi, Silvia Ferro, Eric Zini, Stefano Ricagno

Source: Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/130f3475ad1f49f7b89dafefff585a7e

Mechanisms of Organ Damage and Novel Treatment Targets in AL Amyloidosis

Authors: Francesca Lavatelli

Source: Hemato, Vol 3, Iss 1, Pp 47-62 (2022)

Subject Terms: amyloidosis, immunoglobulin light chains, proteotoxicity, organ damage, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2673-6357/3/1/5; https://doaj.org/toc/2673-6357

Access URL: https://doaj.org/article/014a0e71b1e04878bf6acc9fc5a2901a

AA-amyloidosis in cats (Felis catus) housed in shelters.

Authors: Filippo Ferri, Silvia Ferro, Federico Porporato, Carolina Callegari, Chiara Guglielmetti, Maria Mazza, Marta Ferrero, Chiara Crinò, Enrico Gallo, Michele Drigo, Luigi Michele Coppola, Gabriele Gerardi, Tim Paul Schulte, Stefano Ricagno, Monique Vogel, Federico Storni, Martin F Bachmann, Anne-Cathrine Vogt, Serena Caminito, Giulia Mazzini, Francesca Lavatelli, Giovanni Palladini, Giampaolo Merlini, Eric Zini

Source: PLoS ONE, Vol 18, Iss 3, p e0281822 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6be68cb997bf4772b783fa246068499f

Amyloid Formation by Globular Proteins: The Need to Narrow the Gap Between in Vitro and in Vivo Mechanisms

Authors: Giulia Faravelli, Valentina Mondani, P. Patrizia Mangione, Sara Raimondi, Loredana Marchese, Francesca Lavatelli, Monica Stoppini, Alessandra Corazza, Diana Canetti, Guglielmo Verona, Laura Obici, Graham W. Taylor, Julian D. Gillmore, Sofia Giorgetti, Vittorio Bellotti

Source: Frontiers in Molecular Biosciences, Vol 9 (2022)

Subject Terms: amyloidosis, transthyretin, β2-microglobulin, metamorphosis, amyloid, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2022.830006/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/78918c93ba684ff5a907851006159caf

The Protein Network in Subcutaneous Fat Biopsies from Patients with AL Amyloidosis: More Than Diagnosis?

Authors: Dario Di Silvestre, Francesca Brambilla, Francesca Lavatelli, Maila Chirivì, Diana Canetti, Claudia Bearzi, Roberto Rizzi, Johan Bijzet, Bouke P. C. Hazenberg, Vittorio Bellotti, Julian D. Gillmore, Pierluigi Mauri

Source: Cells, Vol 12, Iss 5, p 699 (2023)

Subject Terms: amyloidosis, proteomics, systems biology, networks, PPI, co-expression, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/5/699; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/39a0f2a3a2b944e9a8de31b285312ba1

Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient

Authors: Paolo Swuec, Francesca Lavatelli, Masayoshi Tasaki, Cristina Paissoni, Paola Rognoni, Martina Maritan, Francesca Brambilla, Paolo Milani, Pierluigi Mauri, Carlo Camilloni, Giovanni Palladini, Giampaolo Merlini, Stefano Ricagno, Martino Bolognesi

Source: Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/40c2c81167ec45c9bf6f9207f2cd41b5

Dissecting the Molecular Features of Systemic Light Chain (AL) Amyloidosis: Contributions from Proteomics

Authors: Paola Rognoni, Giulia Mazzini, Serena Caminito, Giovanni Palladini, Francesca Lavatelli

Source: Medicina, Vol 57, Iss 9, p 916 (2021)

Subject Terms: amyloidosis, immunoglobulin light chains, protein misfolding, amyloid fibrils, post-translational modifications, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/1648-9144/57/9/916; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144

Access URL: https://doaj.org/article/2f0f7db8ef4f4c478450e99533c9f375

Systemic amyloidoses and proteomics: The state of the art

Authors: Francesca Lavatelli, Andrea di Fonzo, Giovanni Palladini, Giampaolo Merlini

Source: EuPA Open Proteomics, Vol 11, Iss C, Pp 4-10 (2016)

Subject Terms: Amyloidosis, Clinical proteomics, Tissue biomarkers, Amyloidogenic proteins, Proteotoxicity, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212968516300162; https://doaj.org/toc/2212-9685

Access URL: https://doaj.org/article/de510cac28944f95aafc387a6b12a944

Clinical Amyloid Typing by Proteomics: Performance Evaluation and Data Sharing between Two Centres

Authors: Diana Canetti, Francesca Brambilla, Nigel B. Rendell, Paola Nocerino, Janet A. Gilbertson, Dario Di Silvestre, Andrea Bergamaschi, Francesca Lavatelli, Giampaolo Merlini, Julian D. Gillmore, Vittorio Bellotti, Pierluigi Mauri, Graham W. Taylor

Source: Molecules, Vol 26, Iss 7, p 1913 (2021)

Subject Terms: amyloid proteomics, proteomics platforms, proteomics results validation, LC-MS/MS raw data exchange, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/7/1913; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/c017e28d85fb481d96668e37ce4a88b4

Oral melphalan and dexamethasone grants extended survival with minimal toxicity in AL amyloidosis: long-term results of a risk-adapted approach

Authors: Giovanni Palladini, Paolo Milani, Andrea Foli, Laura Obici, Francesca Lavatelli, Mario Nuvolone, Riccardo Caccialanza, Stefano Perlini, Giampaolo Merlini

Source: Haematologica, Vol 99, Iss 4 (2014)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/7005; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/bbdbd9caf1464b5e9777037bbdfb51bf

A phase II trial of cyclophosphamide, lenalidomide and dexamethasone in previously treated patients with AL amyloidosis

Authors: Giovanni Palladini, Paola Russo, Paolo Milani, Andrea Foli, Francesca Lavatelli, Mario Nuvolone, Stefano Perlini, Giampaolo Merlini

Source: Haematologica, Vol 98, Iss 3 (2013)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/6597; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/6c83da2fbf844c2c9a45aeef9bb141c6

A strategy for synthesis of pathogenic human immunoglobulin free light chains in E. coli.

Authors: Paola Rognoni, Francesca Lavatelli, Simona Casarini, Giovanni Palladini, Laura Verga, Paolo Pedrazzoli, Giovanna Valentini, Giampaolo Merlini, Vittorio Perfetti

Source: PLoS ONE, Vol 8, Iss 9, p e76022 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3785434?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8c96f91cf2294f1993418b6f49e21eef