Temporal and spatial heterogeneity of HER2 status in metastatic colorectal cancer

Authors: Flavia D’Angelo, Franck Monnien, Alexis Overs, Irvin Pem, Fanny Dor, Marine Abad, Sophie Felix, Zohair Selmani, Zaher Lakkis, Christophe Borg, Alexandre Doussot, Fréderic Bibeau, Chloé Molimard

Source: Diagnostic Pathology, Vol 19, Iss 1, Pp 1-9 (2024)

Subject Terms: Colorectal cancer, HER2, Liver metastasis, Tumor heterogeneity, Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/1746-1596

Access URL: https://doaj.org/article/8ccbd117af2444f2ae3f8cb60a65e583

Machine learning evaluation of immune infiltrate through digital tumour score allows prediction of survival outcome in a pooled analysis of three international stage III colon cancer cohortsResearch in context

Authors: Julie Lecuelle, Caroline Truntzer, Debora Basile, Luigi Laghi, Luana Greco, Alis Ilie, David Rageot, Jean-François Emile, Fréderic Bibeau, Julien Taïeb, Valentin Derangere, Come Lepage, François Ghiringhelli

Source: EBioMedicine, Vol 105, Iss , Pp 105207- (2024)

Subject Terms: Tumour infiltrating lymphocytes, Machine learning, Colonic neoplasms, Biomarkers, Prognosis, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396424002421; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/f4866831da2d49b389ebad9f61f0d2b7

CD3-CD8 immune score associated with a clinical score stratifies PDAC prognosis regardless of adjuvant or neoadjuvant chemotherapy

Authors: Coralie Schoumacher, Valentin Derangère, Gwladys Gaudillière-Le Dain, Titouan Huppe, David Rageot, Alis Ilie, Angélique Vienot, Christophe Borg, Franck Monnien, Frederic Bibeau, Caroline Truntzer, François Ghiringhelli

Source: OncoImmunology, Vol 13, Iss 1 (2024)

Subject Terms: Biomarkers, CD3, CD8, immune score, PDAC, prognostic, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/d7de998b11554bb3986b1833080f8892

Deep Multiple Instance Learning Model to Predict Outcome of Pancreatic Cancer Following Surgery

Authors: Caroline Truntzer, Dina Ouahbi, Titouan Huppé, David Rageot, Alis Ilie, Chloe Molimard, Françoise Beltjens, Anthony Bergeron, Angelique Vienot, Christophe Borg, Franck Monnien, Frédéric Bibeau, Valentin Derangère, François Ghiringhelli

Source: Biomedicines, Vol 12, Iss 12, p 2754 (2024)

Subject Terms: biomarker, pancreatic cancer, deep learning, prognostic, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/12/2754; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/6ba57e757918465e9fa79cf5939db8d1

SALL4‐related gene signature defines a specific stromal subset of pancreatic ductal adenocarcinoma with poor prognostic features

Authors: Angélique Vienot, Franck Monnien, Caroline Truntzer, Virginie Mougey, Adeline Bouard, Jean‐René Pallandre, Chloé Molimard, Romain Loyon, Kamal Asgarov, Gerlinde Averous, François Ghiringhelli, Frédéric Bibeau, Paul Peixoto, Christophe Borg

Source: Molecular Oncology, Vol 17, Iss 7, Pp 1356-1378 (2023)

Subject Terms: fibroblast, pancreatic cancer, SALL4, TGF‐β, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/ea9d65ce32e541b799510c0589dc9be3

Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung cancerResearch in context

Authors: François Ghiringhelli, Frederic Bibeau, Laurent Greillier, Jean-David Fumet, Alis Ilie, Florence Monville, Caroline Laugé, Aurélie Catteau, Isabelle Boquet, Amine Majdi, Erwan Morgand, Youssef Oulkhouir, Nicolas Brandone, Julien Adam, Thomas Sbarrato, Alboukadel Kassambara, Jacques Fieschi, Stéphane Garcia, Anne Laure Lepage, Pascale Tomasini, Jérôme Galon

Source: EBioMedicine, Vol 92, Iss , Pp 104633- (2023)

Subject Terms: Digital pathology, Immunoscore-IC, Prognostic marker, Non-small cell lung cancer, Immunotherapy, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396423001986; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/af4bad0461854aff8dc0c5518a34fcbc

Using a convolutional neural network for classification of squamous and non-squamous non-small cell lung cancer based on diagnostic histopathology HES images

Authors: Anne Laure Le Page, Elise Ballot, Caroline Truntzer, Valentin Derangère, Alis Ilie, David Rageot, Frederic Bibeau, Francois Ghiringhelli

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/74ac5820612a46008b10fb9d90971185

Contribution of the IdyllaTM System to Improving the Therapeutic Care of Patients with NSCLC through Early Screening of EGFR Mutations

Authors: Constance Petiteau, Gwladys Robinet-Zimmermann, Adèle Riot, Marine Dorbeau, Nicolas Richard, Cécile Blanc-Fournier, Frédéric Bibeau, Simon Deshayes, Emmanuel Bergot, Radj Gervais, Guénaëlle Levallet

Source: Current Oncology, Vol 28, Iss 6, Pp 4432-4445 (2021)

Subject Terms: non-small cell lung cancer, molecular diagnosis, EGFR mutations, NGS, IdyllaTM, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/28/6/376; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/c8f725deb2634398a7029bf93649f886

Postoperative circulating tumor DNA detection is associated with the risk of recurrence in patients resected for a stage II colorectal cancer

Authors: Adrien Grancher, Ludivine Beaussire, Sylvain Manfredi, Karine Le Malicot, Marie Dutherage, Vincent Verdier, Claire Mulot, Olivier Bouché, Jean-Marc Phelip, Charles-Briac Levaché, Philippe Deguiral, Sophie Coutant, David Sefrioui, Jean-François Emile, Pierre Laurent-Puig, Frédéric Bibeau, Pierre Michel, Nasrin Sarafan-Vasseur, Côme Lepage, Frederic Di Fiore

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: circulating tumor DNA, liquid biopsy, colorectal cancer, stage II, next generation sequencing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.973167/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/41144a49e2c646378fbff7e5463cb372

Is cancer biology different in older patients?

Authors: Yannick Van Herck, MD, Annelies Feyaerts, MD, Shabbir Alibhai, ProfMD, Demetris Papamichael, MBBS, Lore Decoster, MD, Yentl Lambrechts, Michael Pinchuk, Oliver Bechter, MD, Jaime Herrera-Caceres, MD, Frédéric Bibeau, MD, Christine Desmedt, PhD, Sigrid Hatse, PhD, Hans Wildiers, ProfPhD

Source: The Lancet. Healthy Longevity, Vol 2, Iss 10, Pp e663-e677 (2021)

Subject Terms: Geriatrics, RC952-954.6, Medicine

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666756821001793; https://doaj.org/toc/2666-7568

Access URL: https://doaj.org/article/ed2a58c7b08b443b8f528cd07ebde730

Complete pathologic response after two-stage cytoreductive surgery with HIPEC for bulky pseudomyxoma peritonei: proof of concept

Authors: Olivia Sgarbura, Mohammed Al Hosni, Andrea Petruzziello, Rodrigo Figueroa, Lakhdar Khellaf, Marie-Hélène Pissas, Sébastien Carrère, Stephanie Nougaret, Frédéric Bibeau, François Quénet

Source: International Journal of Hyperthermia, Vol 37, Iss 1, Pp 585-591 (2020)

Subject Terms: pseudomyxoma peritonei, cytoreductive surgery, hyperthermic intraperitoneal chemotherapy, two-stage surgery, oxaliplatin, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/0265-6736; https://doaj.org/toc/1464-5157

Access URL: https://doaj.org/article/d15892c88977457f9133a71739f07e7c

Prognostic value of Thyroid Transcription Factor-1 expression in lung adenocarcinoma in patients treated with anti PD-1/PD-L1

Authors: Loïck Galland, Anne Laure Le Page, Julie Lecuelle, Frederic Bibeau, Youssef Oulkhouir, Valentin Derangère, Caroline Truntzer, François Ghiringhelli

Source: OncoImmunology, Vol 10, Iss 1 (2021)

Subject Terms: adenocarcinoma lung cancer, immunotherapy, kras, lipi score, ttf1, prognostic factors, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/3a0513443c744c029e77bc0183d2f965

A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers

Authors: Anthony Ferrari, Anne Vincent-Salomon, Xavier Pivot, Anne-Sophie Sertier, Emilie Thomas, Laurie Tonon, Sandrine Boyault, Eskeatnaf Mulugeta, Isabelle Treilleux, Gaëtan MacGrogan, Laurent Arnould, Janice Kielbassa, Vincent Le Texier, Hélène Blanché, Jean-François Deleuze, Jocelyne Jacquemier, Marie-Christine Mathieu, Frédérique Penault-Llorca, Frédéric Bibeau, Odette Mariani, Cécile Mannina, Jean-Yves Pierga, Olivier Trédan, Thomas Bachelot, Hervé Bonnefoi, Gilles Romieu, Pierre Fumoleau, Suzette Delaloge, Maria Rios, Jean-Marc Ferrero, Carole Tarpin, Catherine Bouteille, Fabien Calvo, Ivo Glynne Gut, Marta Gut, Sancha Martin, Serena Nik-Zainal, Michael R. Stratton, Iris Pauporté, Pierre Saintigny, Daniel Birnbaum, Alain Viari, Gilles Thomas

Source: Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ab0d2ca4b11b4f8888dd3d70ad443efe

Specific extracellular matrix remodeling signature of colon hepatic metastases.

Authors: Maguy Del Rio, Caroline Mollevi, Nadia Vezzio-Vie, Frédéric Bibeau, Marc Ychou, Pierre Martineau

Source: PLoS ONE, Vol 8, Iss 9, p e74599 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3762755?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/fe4b902b18404ddda0521a775e6d93fb