Long-term Outcomes from a Phase 2 Study of Neoadjuvant Chemotherapy for Muscle-invasive Bladder Cancer (SWOG S1314; NCT02177695)

Authors: Flaig, Thomas W., Tangen, Catherine M., Daneshmand, Siamak, Alva, Ajjai Shivaram, Lucia, M. Scott, McConkey, David James, Theodorescu, Dan, Goldkorn, Amir, Milowsky, Matthew I., Bangs, Rick, MacVicar, Gary R., Bastos, Bruno R., Fowles, Jared S., Gustafson, Daniel L., Plets, Melissa, Thompson, Ian M., Lerner, Seth P.

Source: European urology. 84(3):341-347

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195205337.0x000001&indx=1&recIds=ETOCvdc_100195205337.0x000001

Hepcidin is elevated in primary and secondary myelofibrosis and remains elevated in patients treated with ruxolitinib

Authors: Zhou, Amy, Kong, Tim, Fowles, Jared S., Jung, Chun‐Ling, Allen, Maggie J., Fisher, Daniel A. C., Fulbright, Mary, Nemeth, Elizabeta, Ganz, Tomas, Oh, Stephen T.

Source: British journal of haematology. 197(4):e49-e52

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151815689.0x000001&indx=1&recIds=ETOCvdc_100151815689.0x000001

RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia.

Authors: Kong, Tim, Laranjeira, Angelo B. A., Letson, Christopher T., Yu, LaYow, Lin, Shuyang, Fowles, Jared S., Fisher, Daniel A. C., Ng, Sherwin, Yang, Wei, He, Fan, Youn, Minyoung, Mark, Kailen, Jose, Ana San, Liu, Jingxian, Kim, Alexander B., Cox, Maggie J., Fulbright, Mary C., Jayanthan, Aarthi, Los, Gerrit, Rentschler, Stacey L.

Source: Nature Communications; 1/16/2025, Vol. 16 Issue 1, p1-20, 20p

Subject Terms: ACUTE myeloid leukemia, MYELOPROLIFERATIVE neoplasms, MEDICAL sciences, TUMOR necrosis factors, MOUSE leukemia

Young versus old age at diagnosis confers distinct genomic profiles in patients with polycythemia vera

Authors: Fowles, Jared, How, Joan, Allen, Maggie, Oh, Stephen

Source: Leukemia. 33(6):1522-1526

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153493196.0x000001&indx=1&recIds=ETOCvdc_100153493196.0x000001

SWOG S1314: A randomized phase II study of co-expression extrapolation (COXEN) with neoadjuvant chemotherapy for localized, muscle-invasive bladder cancer with overall survival follow up.

Authors: Flaig, Thomas W., Tangen, Catherine, Daneshmand, Siamak, Alva, Ajjai Shivaram, Lucia, M. Scott, McConkey, David, Theodorescu, Dan, Goldkorn, Amir, Milowsky, Matthew I., Bangs, Rick, MacVicar, Gary R., Bastos, Bruno R., Fowles, Jared, Gustafson, Daniel, Plets, Melissa, Thompson, Ian Murchie, Lerner, Seth P.

Source: Journal of clinical oncology. 40(6 suppl):536-536

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152996874.0x000001&indx=1&recIds=ETOCvdc_100152996874.0x000001

RSK1 Is an Exploitable Dependency in Myeloid Malignancies

Authors: Kong, Tim, Laranjeira, Angelo B. A., Yu, LaYow, Fowles, Jared Scott, Fisher, Daniel A.C., Ng, Sherwin, Yang, Wei, He, Fan, Cox, Maggie J, Fulbright, Mary C., Rentschler, Stacey L., Huynh, My-my, Los, Gerrit, Dunn, Sandra E., Challen, Grant A, Oh, Stephen T.

Source: In Blood 2 November 2023 142 Supplement 1:46-46

Of Elephants and Other Mammals: A Comparative Review of Reproductive Tumors and Potential Impact on Conservation.

Authors: Abegglen, Lisa M., Harrison, Tara M., Moresco, Anneke, Fowles, Jared S., Troan, Brigid V., Kiso, Wendy K., Schmitt, Dennis, Boddy, Amy M., Schiffman, Joshua D.

Source: Animals (2076-2615); Aug2022, Vol. 12 Issue 15, p2005-2005, 18p

Subject Terms: ELEPHANTS, AFRICAN elephant, ASIATIC elephant, MAMMALS, COMPARATIVE method, GENITALIA, ENDANGERED species, HUMAN fertility

Targeting RSK1-Mediated Dependency and Inflammation in Myeloid Malignancies

Authors: Kong, Tim, Laranjeira, Angelo BA ^*, Yu, LaYow ^*, Fowles, Jared S., He, Fan, Allen, Maggie J. ^*, Oh, Stephen T

Source: In Blood 15 November 2022 140 Supplement 1:6724-6725

Molecular Landscape of Canine Osteosarcoma

Authors: Das, Sunetra, Idate, Rupa, Fowles, Jared S., Lana, Susan E., Regan, Daniel P., Gustafson, Daniel L., Duval, Dawn L.

Source: FASEB journal. 34(S1):1-1

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140408159.0x000001&indx=1&recIds=ETOCvdc_100140408159.0x000001

Intra- and interspecies gene expression models for predicting drug response in canine osteosarcoma.

Authors: Fowles, Jared S.^1,2, Brown, Kristen C.³, Hess, Ann M.⁴, Duval, Dawn L.^1,2, Gustafson, Daniel L.^1,2,5 Daniel.Gustafson@ColoState.edu

Source: BMC Bioinformatics. 2/19/2016, Vol. 17, p1-14. 14p. 1 Diagram, 3 Charts, 4 Graphs.

Subject Terms: *GENOMICS, *CANCER treatment, *OSTEOSARCOMA, *CARBOPLATIN, *BONE tumors

Immune pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma.

Authors: Das, Sunetra, Idate, Rupa, Regan, Daniel P., Fowles, Jared S., Lana, Susan E., Thamm, Douglas H., Gustafson, Daniel L., Duval, Dawn L.

Source: Communications Biology; 10/11/2021, Vol. 4 Issue 1, p1-15, 15p

Subject Terms: SOMATIC mutation, OSTEOSARCOMA, MISSENSE mutation, MYELOID cells, DRUG target, SURVIVAL rate, GENE expression profiling

Prospective clinical trial testing COXEN-based gene expression models of chemosensitivity in dogs with spontaneous osteosarcoma.

Authors: Gustafson, Daniel L., Collins, Keagan P., Fowles, Jared S., Ehrhart, E. J., Weishaar, Kristen M., Das, Sunetra, Duval, Dawn L., Thamm, Douglas H.

Source: Cancer Chemotherapy & Pharmacology; Oct2021, Vol. 88 Issue 4, p699-712, 14p

Subject Terms: GENE expression, OVERALL survival, OSTEOSARCOMA, CLINICAL trials, DOGS

Inflammatory Pathophysiology as a Contributor to Myeloproliferative Neoplasms.

Authors: Fisher, Daniel Arthur Corpuz, Fowles, Jared Scott, Zhou, Amy, Oh, Stephen Tracy

Source: Frontiers in Immunology; 6/1/2021, Vol. 12, p1-26, 26p

Subject Terms: MYELOFIBROSIS, TUMOR necrosis factors, EXTRAMEDULLARY hematopoiesis, PATHOLOGICAL physiology, POLYCYTHEMIA vera, BONE remodeling

Co-evolution of tumor and immune cells during progression of multiple myeloma.

Authors: Liu, Ruiyang, Gao, Qingsong, Foltz, Steven M., Fowles, Jared S., Yao, Lijun, Wang, Julia Tianjiao, Cao, Song, Sun, Hua, Wendl, Michael C., Sethuraman, Sunantha, Weerasinghe, Amila, Rettig, Michael P., Storrs, Erik P., Yoon, Christopher J., Wyczalkowski, Matthew A., McMichael, Joshua F., Kohnen, Daniel R., King, Justin, Goldsmith, Scott R., O'Neal, Julie

Source: Nature Communications; 5/7/2021, Vol. 12 Issue 1, p1-18, 18p

Subject Terms: MULTIPLE myeloma, PLASMA cells, PLASMACYTOMA, COEVOLUTION, INCURABLE diseases, B cells

DUSP6 Mediates Resistance to JAK2 Inhibition and Drives Myeloproliferative Neoplasm Disease Progression

Authors: Kong, Tim, Laranjeira, Angelo BA, Yang, Kangning, Fisher, Daniel AC, Yu, LaYow, Wang, Anthony Z, Ruzinova, Marianna B., Fowles, Jared S., Allen, Maggie J., Celik, Hamza, Challen, Grant A., Huang, Sidong, Oh, Stephen T.

Source: In Blood 23 November 2021 138 Supplement 1:55-55

Altered Dynamics of Monocyte Subpopulations and Pro-Inflammatory Signaling Pathways in Polycythemia Vera Revealed By Mass Cytometry

Authors: Fowles, Jared S, Fisher, Daniel A.C. ^*, Zhou, Amy, Oh, Stephen T.

Source: In Blood 13 November 2019 134 Supplement 1:4210-4210

Single-Cell Pathway Enrichment and Regulatory Profiling of Multiple Myeloma across Disease Stages

Authors: Wang, Tianjiao ^*, Sun, Hua ^*, Cui Zhou, Daniel ^*, Liu, Ruiyang ^*, Yao, Lijun ^*, Fiala, Mark A. ^*, Kohnen, Daniel R. ^*, O'Neal, Julie ^*, Rettig, Michael P., Fowles, Jared S, Oh, Stephen T., Jayasinghe, Reyka G ^*, Vij, Ravi, DiPersio, John F., Ding, Li ^*

Source: In Blood 13 November 2019 134 Supplement 1:364-364

Young Versus Old Age at Diagnosis Confers Distinct Genomic Profiles in Patients with Polycythemia Vera

Authors: Fowles, Jared S, How, Chi-Joan, Oh, Stephen T

Source: In Blood 29 November 2018 132 Supplement 1:4322-4322

Hepcidin Is Elevated in Primary and Secondary Myelofibrosis and Correlates with IL-6 and IL-2Rα but Is High in Patients Treated with Ruxolitinib

Authors: Zhou, Amy, Allen, Maggie J. ^*, Fulbright, Mary ^*, Fowles, Jared S, Fisher, Daniel A.C. ^*, Oh, Stephen T

Source: In Blood 29 November 2018 132 Supplement 1:1760-1760

Identification of functionally primitive and immunophenotypically distinct subpopulations in secondary acute myeloid leukemia by mass cytometry.

Authors: Bandyopadhyay, Shovik, Fowles, Jared S., Yu, Liyang, Fisher, Daniel A.C., Oh, Stephen T.

Source: Cytometry. Part B; Jan2019, Vol. 96 Issue 1, p46-56, 11p