A preparative mass spectrometer to deposit intact large native protein complexes

Authors: Fremdling, Paul, Esser, Tim K., Saha, Bodhisattwa, Makarov, Alexander, Fort, Kyle, Reinhardt-Szyba, Maria, Gault, Joseph, Rauschenbach, Stephan

Subject Terms: Quantitative Biology - Biomolecules

Access URL: http://arxiv.org/abs/2203.04671

Full Mass Range ΦSDM Orbitrap Mass Spectrometry for DIA Proteome Analysis

Authors: Steigerwald, Sophia, Sinha, Ankit, Fort, Kyle L., Zeng, Wen-Feng, Niu, Lili, Wichmann, Christoph, Kreutzmann, Arne, Mourad, Daniel, Aizikov, Konstantin, Grinfeld, Dmitry, Makarov, Alexander, Mann, Matthias, Meier, Florian

Source: In Molecular & Cellular Proteomics February 2024 23(2)

Characterization of an Omnitrap-Orbitrap Platform Equipped with Infrared Multiphoton Dissociation, Ultraviolet Photodissociation, and Electron Capture Dissociation for the Analysis of Peptides and Proteins

Authors: Smyrnakis, Athanasios, Levin, Nikita, Kosmopoulou, Mariangela, Jha, Ajay, Fort, Kyle, Makarov, Alexander, Papanastasiou, Dimitris, Mohammed, Shabaz

Source: Analytical chemistry. 95(32):12039-12046

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633542465&indx=1&recIds=ETOCRN633542465

Expanding Orbitrap Collision Cross-Section Measurements to Native Protein Applications Through Kinetic Energy and Signal Decay Analysis

Authors: James, Virginia K., Sanders, James D., Aizikov, Konstantin, Fort, Kyle L., Grinfeld, Dmitry, Makarov, Alexander, Brodbelt, Jennifer S.

Source: Analytical chemistry. 95(19):7656-7664

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632558545&indx=1&recIds=ETOCRN632558545

Advancing Orbitrap Measurements of Collision Cross Sections to Multiple Species for Broad Applications

Authors: James, Virginia K., Sanders, James D., Aizikov, Konstantin, Fort, Kyle L., Grinfeld, Dmitry, Makarov, Alexander, Brodbelt, Jennifer S.

Source: Analytical chemistry. 94(45):15613-15620

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630657245&indx=1&recIds=ETOCRN630657245

Nanohydrophobic Interaction Chromatography Coupled to Ultraviolet Photodissociation Mass Spectrometry for the Analysis of Intact Proteins in Low Charge States

Authors: Blevins, Molly S., Juetten, Kyle J., James, Virginia K., Butalewicz, Jamie P., Escobar, Edwin E., Lanzillotti, Michael B., Sanders, James D., Fort, Kyle L., Brodbelt, Jennifer S.

Source: Journal of proteome research. 21(10):2493-2503

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630429377&indx=1&recIds=ETOCRN630429377

Enhanced Spatial Mapping of Histone Proteoforms in Human Kidney Through MALDI-MSI by High-Field UHMR-Orbitrap Detection

Authors: Zemaitis, Kevin J., Veličković, Dušan, Kew, William, Fort, Kyle L., Reinhardt-Szyba, Maria, Pamreddy, Annapurna, Ding, Yanli, Kaushik, Dharam, Sharma, Kumar, Makarov, Alexander A.

Source: Analytical chemistry. 94(37):12604-12613

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN630187215&indx=1&recIds=ETOCRN630187215

Exploring the Potential of Electrospray-Orbitrap for Stable Isotope Analysis Using Nitrate as a Model

Authors: Hilkert, Andreas, Böhlke, John K., Mroczkowski, Stanley J., Fort, Kyle L., Aizikov, Konstantin, Wang, Xingchen T., Kopf, Sebastian H., Neubauer, Cajetan

Source: Analytical chemistry. 93(26):9139-9148

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627028311&indx=1&recIds=ETOCRN627028311

Vacuum Laser Photoionization inside the C-trap of an Orbitrap Mass Spectrometer: Resonance-Enhanced Multiphoton Ionization High-Resolution Mass Spectrometry

Authors: Kösling, Paul, Rüger, Christopher P., Schade, Julian, Fort, Kyle L., Ehlert, Sven, Irsig, Robert, Kozhinov, Anton N., Nagornov, Konstantin O., Makarov, Alexander, Rigler, Martin

Source: Analytical chemistry. 93(27):9418-9427

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627067172&indx=1&recIds=ETOCRN627067172

A Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients

Authors: Bekker-Jensen, Dorte B. ^{‡, **, ‖}, Martínez-Val, Ana ^{‡, ‖}, Steigerwald, Sophia ^‡, Rüther, Patrick ^‡, Fort, Kyle L. ^§, Arrey, Tabiwang N. ^§, Harder, Alexander ^§, Makarov, Alexander ^§, Olsen, Jesper V. ^{‡, ¶}

Source: In Molecular & Cellular Proteomics April 2020 19(4):716-729

To 200,000 m/z and Beyond: Native Electron Capture Charge Reduction Mass Spectrometry Deconvolves Heterogeneous Signals in Large Biopharmaceutical Analytes.

Authors: Le Huray, Kyle I. P., Wörner, Tobias P., Moreira, Tiago, Dembek, Marcin, Reinhardt-Szyba, Maria, Devine, Paul W. A., Bond, Nicholas J., Fort, Kyle L., Makarov, Alexander A., Sobott, Frank

Source: ACS Central Science; 8/28/2024, Vol. 10 Issue 8, p1548-1561, 14p

To 200,000 m/zand Beyond: Native Electron Capture Charge Reduction Mass Spectrometry Deconvolves Heterogeneous Signals in Large Biopharmaceutical Analytes

Authors: Le Huray, Kyle I. P., Wörner, Tobias P., Moreira, Tiago, Dembek, Marcin, Reinhardt-Szyba, Maria, Devine, Paul W. A., Bond, Nicholas J., Fort, Kyle L., Makarov, Alexander A., Sobott, Frank

Source: ACS Central Science; August 2024, Vol. 10 Issue: 8 p1548-1561, 14p

Simultaneous targeted and discovery-driven clinical proteotyping using hybrid-PRM/DIA.

Authors: Goetze, Sandra, van Drogen, Audrey, Albinus, Jonas B., Fort, Kyle L., Gandhi, Tejas, Robbiani, Damiano, Laforte, Véronique, Reiter, Lukas, Levesque, Mitchell P., Xuan, Yue, Wollscheid, Bernd

Source: Clinical Proteomics; 4/2/2024, Vol. 21 Issue 1, p1-12, 12p

Subject Terms: DETECTION limit, ACQUISITION of data, PEPTIDES, CYCLIN-dependent kinases, DIGITIZATION

Exploring ECD on a Benchtop Q Exactive Orbitrap Mass Spectrometer

Authors: Fort, Kyle L., Cramer, Christian N., Voinov, Valery G., Vasil ev, Yury V., Lopez, Nathan I., Beckman, Joseph S., Heck, Albert J. R.

Source: Journal of proteome research. 17(2):926-933

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN614661019&indx=1&recIds=ETOCRN614661019

Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods

Authors: Waterbeemd, Michiel, Tamara, Sem, Fort, Kyle, Damoc, Eugen, Franc, Vojtech, Bieri, Philipp, Itten, Martin, Makarov, Alexander, Ban, Nenad, Heck, Albert

Source: Nature communications. 9(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170089013.0x000001&indx=1&recIds=ETOCvdc_100170089013.0x000001

Cryogenic Ion Mobility-Mass Spectrometry: Tracking Ion Structure from Solution to the Gas Phase

Authors: Servage, Kelly A., Silveira, Joshua A., Fort, Kyle L., Russell, David H.

Source: Accounts of chemical research. 49(7):1421-1428

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631091840&indx=1&recIds=ETOCRN631091840

Symmetry of Charge Partitioning in Collisional and UV Photon-Induced Dissociation of Protein Assemblies

Authors: Tamara, Sem, Dyachenko, Andrey, Fort, Kyle L., Makarov, Alexander A., Scheltema, Richard A., Heck, Albert J. R.

Source: Journal of the American Chemical Society. 138(34):10860-10868

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN607879915&indx=1&recIds=ETOCRN607879915

Implementation of Ultraviolet Photodissociation on a Benchtop Q Exactive Mass Spectrometer and Its Application to Phosphoproteomics

Authors: Fort, Kyle L., Dyachenko, Andrey, Potel, Clement M., Corradini, Eleonora, Marino, Fabio, Barendregt, Arjan, Makarov, Alexander A., Scheltema, Richard A., Heck, Albert J. R.

Source: Analytical chemistry. 88(4):2303-2310

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN605096837&indx=1&recIds=ETOCRN605096837

Ultralong transients enhance sensitivity and resolution in Orbitrap-based single-ion mass spectrometry

Authors: Deslignière, Evolène, Yin, Victor C., Ebberink, Eduard H. T. M., Rolland, Amber D., Barendregt, Arjan, Wörner, Tobias P., Nagornov, Konstantin O., Kozhinov, Anton N., Fort, Kyle L., Tsybin, Yury O., Makarov, Alexander A., Heck, Albert J. R.

Source: Nature Methods; 20240101, Issue: Preprints p1-4, 4p

Unfolding of Hydrated Alkyl Diammonium Cations Revealed by Cryogenic Ion Mobility-Mass Spectrometry

Authors: Servage, Kelly A., Fort, Kyle L., Silveira, Joshua A., Shi, Liuqing, Clemmer, David E., Russell, David H.

Source: Journal of the American Chemical Society. 137(28):8916-8919

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN602165485&indx=1&recIds=ETOCRN602165485