Epigenetic control of multiple genes with a lentiviral vector encoding transcriptional repressors fused to compact zinc finger arrays

Authors: Monteferrario, Davide, David, Marion, Tadi, Satish K., Zhou, Yuanyue, Marchetti, Irène, Jeanneau, Caroline, Saviane, Gaëlle, Dupont, Coralie F., Martelli, Angélique E., Truong, Lynn N., Eshleman, Jason A., Ng, Colman C., Huston, Marshall W., Davis, Gregory D., Fontenot, Jason D., Reik, Andreas, Rosa, Maurus de la, Fenard, David

Source: In Molecular Therapy - Methods & Clinical Development 13 June 2024 32(2)

Production of therapeutic levels of human FIX-R338L by engineered B cells using GMP-compatible medium

Authors: David, Marion, Monteferrario, Davide, Saviane, Gaëlle, Jeanneau, Caroline, Marchetti, Irène, Dupont, Coralie F., Dumont, Céline, Fontenot, Jason D., Rosa, Maurus de la, Fenard, David

Source: In Molecular Therapy - Methods & Clinical Development 14 December 2023 31

Investigating small molecules to inhibit germinal center kinase-like kinase (GLK/MAP4K3) upstream of PKCθ phosphorylation: Potential therapy to modulate T cell dependent immunity

Authors: May-Dracka, Tricia L., Arduini, Robert, Bertolotti-Ciarlet, Andrea, Bhisetti, Govinda, Brickelmaier, Margot, Cahir-McFarland, Ellen, Enyedy, Istvan, Fontenot, Jason D., Hesson, Thomas, Little, Kevin, Lyssikatos, Joe, Marcotte, Douglas, McKee, Timothy, Murugan, Paramasivam, Patterson, Thomas, Peng, Hairuo, Rushe, Mia, Silvian, Laura, Spilker, Kerri, Wu, Ping, Xin, Zhili, Burkly, Linda C.

Source: Bioorganic & medicinal chemistry letters. 28(10):1964-1971

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116328553.0x000001&indx=1&recIds=ETOCvdc_100116328553.0x000001

Harnessing regulatory T cells to establish immune tolerance.

Authors: Ho, Patrick, Cahir-McFarland, Ellen, Fontenot, Jason D., Lodie, Tracey, Nada, Adel, Tang, Qizhi, Turka, Laurence A., Bluestone, Jeffrey A.

Source: Science Translational Medicine; 3/13/2024, Vol. 16 Issue 738, p1-6, 6p

Subject Terms: REGULATORY T cells, IMMUNOLOGICAL tolerance

DMF, but not other fumarates, inhibits NF-κB activity in vitro in an Nrf2-independent manner

Authors: Gillard, Geoffrey O., Collette, Brian, Anderson, John, Chao, Jianhua, Scannevin, Robert H., Huss, David J., Fontenot, Jason D.

Source: In Journal of Neuroimmunology 15 June 2015 283:74-85

Pillars Article: Foxp3 Programs the Development and Function of CD4^+CD25^+ Regulatory T Cells. Nat. Immunol. 2003. 4: 330—336

Authors: Fontenot, Jason D., Gavin, Marc A., Rudensky, Alexander Y.

Source: Journal of immunology. 198(3):986-992

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN609752244&indx=1&recIds=ETOCRN609752244

Discovery of biaryls as RORγ inverse agonists by using structure-based design

Authors: Enyedy, Istvan J., Powell, Noel A., Caravella, Justin, van Vloten, Kurt, Chao, Jianhua, Banerjee, Daliya, Marcotte, Douglas, Silvian, Laura, McKenzie, Andres, Hong, Victor Sukbong, Fontenot, Jason D.

Source: Bioorganic & medicinal chemistry letters. 26(10):2459-2463

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129399080.0x000001&indx=1&recIds=ETOCvdc_100129399080.0x000001

Circulating innate lymphoid cells are unchanged in response to DAC HYP therapy

Authors: Gillard, Geoffrey O., Saenz, Steven A., Huss, David J., Fontenot, Jason D.

Source: JOURNAL OF NEUROIMMUNOLOGY. 294:41-45

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100066109567.0x000001&indx=1&recIds=ETOCvdc_100066109567.0x000001

Foxp3-dependent programme of regulatory T-cell differentiation.

Authors: Gavin, Marc A., Rasmussen, Jeffrey P., Fontenot, Jason D.

Source: Nature; February 15 2007, Vol. 445, p771-775, 5p

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

Authors: Fontenot, Jason D. ^*, Rasmussen, Jeffrey P., Williams, Luke M., Dooley, James L., Farr, Andrew G., Rudensky, Alexander Y. ^*

Source: In Immunity 2005 22(3):329-341

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors.

Authors: Ozinsky, Adrian, Underhill, David M., Fontenot, Jason D.

Source: Proceedings of the National Academy of Sciences of the United States of America; December 5 2000, Vol. 97 Issue 25, p13766-13771, 6p

Molecular aspects of regulatory T cell development

Authors: Fontenot, Jason D, Rudensky, Alexander Y

Source: In Seminars in Immunology 2004 16(2):73-80

Group 1 ILCs regulate T cell–mediated liver immunopathology by controlling local IL-2 availability.

Authors: Fumagalli, Valeria, Venzin, Valentina, Lucia, Pietro Di, Moalli, Federica, Ficht, Xenia, Ambrosi, Gioia, Giustini, Leonardo, Andreata, Francesco, Grillo, Marta, Magini, Diletta, Ravà, Micol, Friedrich, Christin, Fontenot, Jason D., Bousso, Philippe, Gilmore, Sarah A., Khan, Shahzada, Baca, Manuel, Vivier, Eric, Gasteiger, Georg, Kuka, Mirela

Source: Science Immunology; 2022, Vol. 7 Issue 68, p1-15, 15p, 6 Graphs

A function for interleukin 2 in Foxp3-expressing regulatory T cells.

Authors: Fontenot, Jason D.^1,2 jfontenot@rockefeller.edu, Rasmussen, Jeffrey P.¹, Gavin, Marc A.¹, Rudensky, Alexander Y.¹

Source: Nature Immunology. Nov2005, Vol. 6 Issue 11, p1142-1151. 10p. 1 Diagram, 6 Graphs.

Subject Terms: *T cells, *INTERLEUKIN-2, *IMMUNOMODULATORS, *CELLULAR control mechanisms, *CELL proliferation, *PHYSIOLOGICAL control systems

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

Authors: Fontenot, Jason D.¹, Rudensky, Alexander Y.^1,2 aruden@u.washington.edu

Source: Nature Immunology. Apr2005, Vol. 6 Issue 4, p331-337. 7p.

Subject Terms: *ANTIGENS, *LYMPHOCYTES, *TRANSCRIPTION factors, *CELLULAR mechanics, *T cells, *IMMUNE response

Foxp3 programs the development and function of CD4⁺CD25⁺ regulatory T cells.

Authors: Fontenot, Jason D., Gavin, Marc A., Rudensky, Alexander Y.

Source: Nature Immunology. Apr2003, Vol. 4 Issue 4, p330. 7p.

Subject Terms: *T cells, *AUTOIMMUNITY, *TRANSCRIPTION factors

Characterization of the Impact of Daclizumab Beta on Circulating Natural Killer Cells by Mass Cytometry.

Authors: Ranganath, Thanmayi, Simpson, Laura J., Ferreira, Anne-Maud, Seiler, Christof, Vendrame, Elena, Zhao, Nancy, Fontenot, Jason D., Holmes, Susan, Blish, Catherine A.

Source: Frontiers in Immunology; 4/24/2020, Vol. 11, p1-13, 13p

Subject Terms: KILLER cells, CYTOMETRY, MASS murderers, TREATMENT effectiveness, T cells

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