Systemic inflammation activates coagulation and immune cell infiltration pathways in brains with propagating α-synuclein fibril aggregates

Authors: Laursen, Anne-Line Strange, Olesen, Mikkel Vestergaard, Folke, Jonas, Brudek, Tomasz, Knecht, Luisa Harriet, Sotty, Florence, Lambertsen, Kate Lykke, Fog, Karina, Dalgaard, Louise Torp, Aznar, Susana

Source: In Molecular and Cellular Neuroscience June 2024 129

Assessing serum anti-nuclear antibodies HEp-2 patterns in synucleinopathies.

Authors: Folke, Jonas^1,2 (AUTHOR), Skougaard, Marie^2,3 (AUTHOR), Korsholm, Trine-Line³ (AUTHOR), Laursen, Anne-Line Strange^1,2 (AUTHOR), Salvesen, Lisette^4,5 (AUTHOR), Hejl, Anne-Mette^4,5 (AUTHOR), Bech, Sara⁴ (AUTHOR), Løkkegaard, Annemette^4,5 (AUTHOR), Brudek, Tomasz^1,2 (AUTHOR), Ditlev, Sisse Bolm² (AUTHOR), Aznar, Susana^1,2 (AUTHOR) Susana.aznar.kleijn@regionh.dk

Source: Immunity & Ageing. 7/18/2024, Vol. 21 Issue 1, p1-6. 6p.

Subject Terms: *ANTINUCLEAR factors, *LEWY body dementia, *MULTIPLE system atrophy, *PARKINSON'S disease, *IMMUNE system

Alpha-synuclein Immunization Strategies for Synucleinopathies in Clinical Studies: A Biological Perspective

Authors: Knecht, Luisa, Folke, Jonas, Dodel, Richard, Ross, J. Alexander, Albus, Alexandra

Source: In Neurotherapeutics September 2022 19(5):1489-1502

Cerebrospinal fluid and plasma distribution of anti-α-synuclein IgMs and IgGs in multiple system atrophy and Parkinson's disease

Authors: Folke, Jonas, Rydbirk, Rasmus, Løkkegaard, Annemette, Hejl, Anne-Mette, Winge, Kristian, Starhof, Charlotte, Salvesen, Lisette, Pedersen, Lars Østergaard, Aznar, Susana, Pakkenberg, Bente, Brudek, Tomasz

Source: In Parkinsonism and Related Disorders June 2021 87:98-104

Autoantibody profiles in Alzheimer´s, Parkinson´s, and dementia with Lewy bodies: altered IgG affinity and IgG/IgM/IgA responses to alpha-synuclein, amyloid-beta, and tau in disease-specific pathological patterns.

Authors: Knecht, Luisa, Dalsbøl, Katrine, Simonsen, Anja Hviid, Pilchner, Falk, Ross, Jean Alexander, Winge, Kristian, Salvesen, Lisette, Bech, Sara, Hejl, Anne-Mette, Løkkegaard, Annemette, Hasselbalch, Steen G, Dodel, Richard, Aznar, Susana, Waldemar, Gunhild, Brudek, Tomasz, Folke, Jonas

Source: Journal of Neuroinflammation; 12/3/2024, Vol. 21 Issue 1, p1-14, 14p

Subject Terms: LEWY body dementia, TAU proteins, ALZHEIMER'S disease, PARKINSON'S disease, CHEMILUMINESCENCE assay

DNAJB6 is expressed in neurons and oligodendrocytes of the human brain.

Authors: Hentze, Jónvá, Folke, Jonas, Aznar, Susana, Nyeng, Pia, Brudek, Tomasz, Hansen, Christian

Source: Glia; Dec2024, Vol. 72 Issue 12, p2313-2326, 14p

Increased prefrontal cortex interleukin-2 protein levels and shift in the peripheral T cell population in progressive supranuclear palsy patients

Authors: Rydbirk, Rasmus, Elfving, Betina, Folke, Jonas, Pakkenberg, Bente, Winge, Kristian, Brudek, Tomasz, Aznar, Susana

Source: Scientific reports. 9(1):1-9

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153416278.0x000001&indx=1&recIds=ETOCvdc_100153416278.0x000001

Cytokine profiling in the prefrontal cortex of Parkinson's Disease and Multiple System Atrophy patients

Authors: Rydbirk, Rasmus, Elfving, Betina, Andersen, Mille Dahl, Langbøl, Mia Aggergaard, Folke, Jonas, Winge, Kristian, Pakkenberg, Bente, Brudek, Tomasz, Aznar, Susana

Source: In Neurobiology of Disease October 2017 106:269-278

Alpha-Synuclein Autoimmune Decline in Prodromal Multiple System Atrophy and Parkinson's Disease.

Authors: Folke, Jonas^1,2 (AUTHOR) emil_bergholt@hotmail.com, Bergholt, Emil¹ (AUTHOR) bente.pakkenberg@regionh.dk, Pakkenberg, Bente^1,3 (AUTHOR) susana.aznar.kleijn@regionh.dk, Aznar, Susana^1,2 (AUTHOR) tomasz.brudek@regionh.dk, Brudek, Tomasz^1,2 (AUTHOR)

Source: International Journal of Molecular Sciences. Jun2022, Vol. 23 Issue 12, p6554-6554. 12p.

Subject Terms: *MULTIPLE system atrophy, *PARKINSON'S disease, *ALPHA-synuclein, *AUTOANTIBODIES, *IMMUNOGLOBULIN M, *NEURODEGENERATION

Autoimmune antibody decline in Parkinson's disease and Multiple System Atrophy; a step towards immunotherapeutic strategies

Authors: Brudek, Tomasz, Winge, Kristian, Folke, Jonas, Christensen, Søren, Fog, Karina, Pakkenberg, Bente, Pedersen, Lars

Source: Molecular neurodegeneration. 12(1):1-16

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100133566721.0x000001&indx=1&recIds=ETOCvdc_100133566721.0x000001

Author Correction: Assessment of brain reference genes for RT-qPCR studies in neurodegenerative diseases.

Authors: Rydbirk, Rasmus¹ rasmus.rydbirk@regionh.dk, Folke, Jonas¹, Winge, Kristian^2,3,4, Aznar, Susana¹, Pakkenberg, Bente^1,4, Brudek, Tomasz¹

Source: Scientific Reports. 7/23/2020, Vol. 10 Issue 1, p1-7. 7p.

Subject Terms: *REVERSE transcriptase polymerase chain reaction, *NEURODEGENERATION

TDP-43–specific Autoantibody Decline in Patients With Amyotrophic Lateral Sclerosis

Authors: Nielsen, Anne Kallehauge, Folke, Jonas, Owczarek, Sylwia, Svenstrup, Kirsten, Winge, Kristian, Pakkenberg, Bente, Aznar, Susana, Brudek, Tomasz

Source: Neurology.Neuroimmunology & neuroinflammation. 8(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188268745.0x000001&indx=1&recIds=ETOCvdc_100188268745.0x000001

Epigenetic modulation of AREL1 and increased HLA expression in brains of multiple system atrophy patients

Authors: Rydbirk, Rasmus, Folke, Jonas, Busato, Florence, Roché, Elodie, Chauhan, Alisha Shahzad, Løkkegaard, Annemette, Hejl, Anne-Mette, Bode, Matthias, Blaabjerg, Morten, Møller, Mette, Danielsen, Erik Hvid, Brudek, Tomasz, Pakkenberg, Bente, Tost, Jorg, Aznar, Susana

Source: Acta neuropathologica communications. 8(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164237085.0x000001&indx=1&recIds=ETOCvdc_100164237085.0x000001

Modeling the early stages of Alzheimer's disease by administering intracerebroventricular injections of human native Aβ oligomers to rats.

Authors: Baerends, Eva, Soud, Katia, Folke, Jonas, Pedersen, Anna-Kathrine, Henmar, Simon, Konrad, Lisa, Lycas, Matthew D., Mori, Yuki, Pakkenberg, Bente, Woldbye, David P. D., Dmytriyeva, Oksana, Pankratova, Stanislava

Source: Acta Neuropathologica Communications; 8/16/2022, Vol. 10 Issue 1, p1-21, 21p

Subject Terms: ALZHEIMER'S disease, AMYLOID plaque, MAZE tests, ENTORHINAL cortex, COLLECTIVE memory, RATS, TAU proteins, OLIGOMERS

Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology.

Authors: Rydbirk, Rasmus, Østergaard, Ole, Folke, Jonas, Hempel, Casper, DellaValle, Brian, Andresen, Thomas L., Løkkegaard, Annemette, Hejl, Anne-Mette, Bode, Matthias, Blaabjerg, Morten, Møller, Mette, Danielsen, Erik H., Salvesen, Lisette, Starhof, Charlotte C., Bech, Sara, Winge, Kristian, Rungby, Jørgen, Pakkenberg, Bente, Brudek, Tomasz, Olsen, Jesper V.

Source: Cellular & Molecular Life Sciences; Jun2022, Vol. 79 Issue 6, p1-18, 18p

DNAJB6b is Downregulated in Synucleinopathies.

Authors: Folke, Jonas¹ (AUTHOR), Arkan, Sertan² (AUTHOR), Martinsson, Isak³ (AUTHOR), Aznar, Susana¹ (AUTHOR), Gouras, Gunnar³ (AUTHOR), Brudek, Tomasz¹ (AUTHOR), Hansen, Christian^2,4 (AUTHOR) christian.hansen@med.lu.se

Source: Journal of Parkinson's Disease. 2021, Vol. 11 Issue 4, p1791-1803. 13p.

Subject Terms: *PROGRESSIVE supranuclear palsy, *MULTIPLE system atrophy, *PARKINSONIAN disorders, *DOPAMINERGIC neurons, *PARKINSON'S disease, *SUBSTANTIA nigra

TDP-43–specific Autoantibody Decline in Patients With Amyotrophic Lateral Sclerosis.

Authors: Nielsen, Anne Kallehauge, Folke, Jonas, Owczarek, Sylwia, Svenstrup, Kirsten, Winge, Kristian, Pakkenberg, Bente, Aznar, Susana, Brudek, Tomasz

Source: Neurology® Neuroimmunology & Neuroinflammation; Mar2021, Vol. 8 Issue 2, p1-12, 12p

Passive Immunization in Alpha-Synuclein Preclinical Animal Models.

Authors: Folke, Jonas^1,2,3 (AUTHOR) Jonas.folke@regionh.dk, Ferreira, Nelson⁴ (AUTHOR) nelson@biomed.au.dk, Brudek, Tomasz^2,3 (AUTHOR), Borghammer, Per^5,6 (AUTHOR) borghammer@clin.au.dk, Van Den Berge, Nathalie^5,6 (AUTHOR) Jonas.folke@regionh.dk

Source: Biomolecules (2218-273X). Feb2022, Vol. 12 Issue 2, p168. 1p.

Subject Terms: *ALPHA-synuclein, *LEWY body dementia, *MULTIPLE system atrophy, *ANIMAL models in research, *NEUROGLIA

The A- and B-type muscarinic acetylcholine receptors from Drosophila melanogaster couple to different second messenger pathways

Authors: Ren, Guilin R., Folke, Jonas, Hauser, Frank, Li, Shizhong, Grimmelikhuijzen, Cornelis J.P.

Source: In Biochemical and Biophysical Research Communications 10 July 2015 462(4):358-364

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