Experimental methodology for measuring performance of 3D printed Coiled Flow Reactors

Authors: Josifovic, Aleksandar, Barrera, Maria Cecilia, Leech, Damien, Wildman, Ricky, Alford, Gareth, Florence, Alastair, Brown, Cameron

Source: IEEE EUROCON 2023 - 20th International Conference on Smart Technologies Smart Technologies, IEEE EUROCON 2023 - 20th International Conference on. :717-722 Jul, 2023

Relation: IEEE EUROCON 2023 - 20th International Conference on Smart Technologies

Investigation of aerosol jet printing for the preparation of solid dosage forms

Authors: Turner, Alice J. ^{a, ⁎}, Prasad, Elke ^{a, b}, Florence, Alastair J. ^a, Halbert, Gavin W. ^{a, b}

Source: In International Journal of Pharmaceutics 25 February 2025 671

Probing the interplay between drug saturation, processing temperature and microstructure of amorphous solid dispersions with synchrotron X-ray phase-contrast tomography

Authors: Bordos, Ecaterina ^{a, b, ⁎}, Das, Gunjan ^{c, d, e}, Schroeder, Sven L.M. ^{c, d, e}, Florence, Alastair ^{a, b}, Halbert, Gavin W. ^{a, b}, Robertson, John ^{a, b}

Source: In International Journal of Pharmaceutics 25 January 2025 669

Optimisation of additively manufactured coiled flow inverters for continuous viral inactivation processes

Authors: Barrera, Maria Cecilia ^a, Leech, Damien ^b, Josifovic, Aleksandar ^a, Tolouei, Anita ^c, Alford, Gareth ^d, Wallace, Martin J. ^e, Bennett, Nicholas ^f, Wildman, Ricky ^{b, g}, Irvine, Derek J. ^{b, g}, Croft, Anna ^h, Özcan, Ender ⁱ, Florence, Alastair J. ^a, Johnston, Blair ^a, Robertson, John ^a, Brown, Cameron J. ^{a, ⁎}

Source: In Chemical Engineering Research and Design January 2025 213:126-136

A hybrid system of mixture models for the prediction of particle size and shape, density, and flowability of pharmaceutical powder blends

Authors: Salehian, Mohammad ^{a, b}, Moores, Jonathan ^b, Goldie, Jonathan ^{a, b}, Ibrahim, Isra' ^b, Torrecillas, Carlota Mendez ^b, Wale, Ishwari ^b, Abbas, Faisal ^{a, b}, Maclean, Natalie ^b, Robertson, John ^b, Florence, Alastair ^{a, b}, Markl, Daniel ^{a, b, ⁎}

Source: In International Journal of Pharmaceutics: X December 2024 8

Emerging Applications and Regulatory Strategies for Advanced Medicines Manufacturing – Towards the Development of a Platform Approach

Authors: Srai, Jagjit Singh, Bauer, Paul, Badman, Clive, Bresciani, Massimo, Cooney, Charles L., Florence, Alastair, Hausner, Doug, Konstantinov, Konstantin, Lee, Sau L., Mascia, Salvatore, Nasr, Moheb, Trout, Bernhardt L

Source: In Journal of Pharmaceutical Sciences July 2024 113(7):1701-1710

Digital process design to define and deliver pharmaceutical particle attributes

Authors: Urwin, Stephanie J., Chong, Magdalene W.S., Li, Wei, McGinty, John, Mehta, Bhavik, Ottoboni, Sara, Pathan, Momina, Prasad, Elke, Robertson, Murray, McGowan, Mark, al-Attili, Mais, Gramadnikova, Ekaterina, Siddique, Mariam, Houson, Ian, Feilden, Helen, Benyahia, Brahim, Brown, Cameron J., Halbert, Gavin W., Johnston, Blair, Nordon, Alison, Price, Chris J., Reilly, Chris D., Sefcik, Jan, Florence, Alastair J.

Source: Chemical engineering research & design. 196:726-749

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195177559.0x000001&indx=1&recIds=ETOCvdc_100195177559.0x000001

Machine learning approaches to the prediction of powder flow behaviour of pharmaceutical materials from physical propertiesElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2dd00106c

Authors: Pereira Diaz, Laura, Brown, Cameron J., Ojo, Ebenezer, Mustoe, Chantal, Florence, Alastair J.

Source: Digital discovery. 2(3):692-701

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185114391.0x000001&indx=1&recIds=ETOCvdc_100185114391.0x000001

Machine Learning-Derived Correlations for Scale-Up and Technology Transfer of Primary Nucleation Kinetics

Authors: Yerdelen, Stephanie, Yang, Yihui, Quon, Justin L., Papageorgiou, Charles D., Mitchell, Chris, Houson, Ian, Sefcik, Jan, Horst, Joop H. ter, Florence, Alastair J., Brown, Cameron J.

Source: Crystal growth & design. 23(2):681-693

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631675413&indx=1&recIds=ETOCRN631675413

Predicting pharmaceutical powder flow from microscopy images using deep learning

Authors: Wilkinson, Matthew R., Pereira Diaz, Laura, Vassileiou, Antony D., Armstrong, John A., Brown, Cameron J., Castro-Dominguez, Bernardo, Florence, Alastair J.

Source: Digital discovery. 2(2):459-470

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179155400.0x000001&indx=1&recIds=ETOCvdc_100179155400.0x000001

A unified ML framework for solubility prediction across organic solventsElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2dd00024e

Authors: Vassileiou, Antony D., Robertson, Murray N., Wareham, Bruce G., Soundaranathan, Mithushan, Ottoboni, Sara, Florence, Alastair J., Hartwig, Thoralf, Johnston, Blair F.

Source: Digital discovery. 2(2):356-367

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179155274.0x000001&indx=1&recIds=ETOCvdc_100179155274.0x000001

Expanding the pharmaceutical formulation space in material extrusion 3D printing applications

Authors: Prasad, Elke, Robertson, John, Florence, Alastair J., Halbert, Gavin W.

Source: In Additive Manufacturing 5 September 2023 77

Fusion of laser diffraction and chord length distribution data for estimation of particle size distribution using multi-objective optimisation

Authors: Agimelen, Okpeafoh S., Ferreira, Carla, Ahmed, Bilal, Cardona, Javier, Chen, Yi-chieh, Florence, Alastair J., Andonovic, Ivan, Sefcik, Jan, Mulholland, Anthony J.

Subject Terms: Physics - Data Analysis, Statistics and Probability

Access URL: http://arxiv.org/abs/1804.05633

Effect of oscillatory flow conditions on crystalliser fouling investigated through non-invasive imaging

Authors: Sheridan, Rachel, Cardona, Javier, Tachtatzis, Christos, Chen, Yi-Chieh, Cleary, Alison, Briggs, Naomi, Florence, Alastair, Atkinson, Robert, Michie, Craig, Andonovic, Ivan, Sefcik, Jan

Source: In Chemical Engineering Science 28 April 2022 252

Crystal Structure and Twisted Aggregates of Oxcarbazepine Form III

Authors: Polyzois, Hector, Guo, Rui, Srirambhatla, Vijay K., Warzecha, Monika, Prasad, Elke, Turner, Alice, Halbert, Gavin W., Keating, Patricia, Price, Sarah L., Florence, Alastair J.

Source: Crystal growth & design. 22(7):4146-4156

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632116110&indx=1&recIds=ETOCRN632116110

Direct Image Feature Extraction and Multivariate Analysis for Crystallization Process Characterization

Authors: Doerr, Frederik J. S., Brown, Cameron J., Florence, Alastair J.

Source: Crystal growth & design. 22(4):2105-2116

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632114007&indx=1&recIds=ETOCRN632114007

Data mining crystallization kineticsElectronic supplementary information (ESI) available. See https://doi.org/10.1039/d2dd00033d

Authors: Maldonado, Diego A., Vassileiou, Antony, Johnston, Blair, Florence, Alastair J., Brown, Cameron J.

Source: Digital discovery. 1(5):621-635

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165329409.0x000001&indx=1&recIds=ETOCvdc_100165329409.0x000001

Precrystallization solute assemblies and crystal symmetry

Authors: Warzecha, Monika, Verma, Lakshmanji, Chakrabarti, Rajshree, Hadjiev, Viktor G., Florence, Alastair J., Palmer, Jeremy C., Vekilov, Peter G.

Source: Faraday discussions. 235:307-321

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155566718.0x000001&indx=1&recIds=ETOCvdc_100155566718.0x000001

Monitoring crystal breakage in wet milling processes using inline imaging and chord length distribution measurements

Authors: Agimelen, Okpeafoh S., Svoboda, Vaclav, Ahmed, Bilal, Cardona, Javier, Dziewierz, Jerzy, Brown, Cameron J., McGlone, Thomas, Cleary, Alison, Tachtatzis, Christos, Michie, Craig, Florence, Alastair J., Andonovic, Ivan, Mulholland, Anthony J., Sefcik, Jan

Subject Terms: Physics - Data Analysis, Statistics and Probability

Access URL: http://arxiv.org/abs/1703.09186

Investigation of Wet Milling and Indirect Ultrasound as Means for Controlling Nucleation in the Continuous Crystallization of an Active Pharmaceutical Ingredient

Authors: Yang, Yihui, Ahmed, Bilal, Mitchell, Christopher, Quon, Justin L., Siddique, Humera, Houson, Ian, Florence, Alastair J., Papageorgiou, Charles D.

Source: Organic process research & development. 25(9):2119-2132

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627663400&indx=1&recIds=ETOCRN627663400