Southwest Oncology Group S0826: A phase 2 trial of SCH 727965 (NSC 727135, dinaciclib) in patients with stage IV melanoma.

Authors: Lao, Christopher D., Moon, James, Ma, Vincent T., Fruehauf, John P., Flaherty, Lawrence E., Bury, Martin J., Martin, William G., Gross, Howard, Akerley, Wallace, Hopkins, Judith O., Patel, Sapna P., Sondak, Vernon K., Ribas, Antoni

Source: Cancer (0008543X); Jan2025, Vol. 131 Issue 1, p1-9, 9p

Subject Terms: LACTATE dehydrogenase, OVERALL survival, NULL hypothesis, KINASE inhibitors, THERAPEUTICS, DACARBAZINE

Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial

Authors: Harvey, Vernon, Tomek, Rudolf, Robert, Nicholas J., Gore, Ira, Jr., Smith, John W., II, Masuda, Norikazu, Di Sean Kendall, S., Harker, William Graydon, Petrakova, Katarina, Guerrero Zotano, Angel, Simon, Amparo Ruiz, Konstantinovic, Zora Neskovic, Iannotti, Nicholas O., Tassone, Pierfrancesco, Rodriguez, Gladys I., Jáñez Martinez, Noelia, Crespo Massieu, Carmen, Smickoska, Snezana, Somali, Isil, Yilmaz, Ugur, Alonso, Mirta Garcia, Rosales, Adolfo Murias, Cold, Soeren, Knoop, Ann Soegaard, Patt, Debra, Hellerstedt, Beth A., Morales Murillo, Serafin, Mayer, Ingrid A., Means-Powell, Julie Ann, Hui, Rina, Senecal, Francis M., De Boer, Richard Hendry, Shen, Zhenzhou, Luczak, Adam Andrzej, Chui, Joanna W.Y., Tsang, Janice Wing-hang, Lang, Istvan, Rai, Yoshiaki, Hozumi, Yasuo, Ten Tije, Albert J., Bhandari, Manish, Osborne, Cynthia R.C., Ohtani, Shoichiro, Higaki, Kenji, Watanabe, Kenichi, Taguchi, Kazunori, Takahashi, Masato, Filipovic, Sladjana, Hansen, Vincent L., Rao, Vijayarama Phooshkooru, Gupta, Manish, Petrov, Petar, Coudert, Bruno, Vojnovic, Zeljko, Polya, Zsofia, Miyaki, Toshiko, Yamamoto, Naohito, Brincat, Stephen, Lesniewski-Kmak, Krzysztof, Chmielowska, Ewa, Birhiray, Ruemu E., Citron, Marc L., Papish, Steven William, Berry, William R., Langkjer, Sven Tyge, Garcia Sáenz, José Angel, Arance, Ana Maria, Efrat, Noa, Sarosiek, Tomasz, Grzeda, Lukasz, Manalo, Yvonne, Smith, Julie C., Vaziri, Irfan, Healey, Tabitha, Rahim, Yasmin, Luk, Cynthia, Dingle, Brian, Franco, Sandra, Sorensen, Peter Grundtvig, Anand, Anjana, Khan, Sarah, Fountzilas, George, Aogi, Kenjiro, Shimizu, Satoru, Mikulova, Milada, Spanik, Stanislav, Somer, Robert A., Flynn, Patrick J., Coward, Jermaine, Mainwaring, Paul, Jerusalem, Guy, Segura-Ojezzar, Carine, Levy, Christelle, Delozier, Thierry, Khayat, David, Coleman, Robert E., Rolles, Martin J., Maisano, Robert, Nardi, Mario, Ito, Yoshinori, Yumuk, Perran Fulden, Basaran, Gul, Serdar Turhal, Nazim, Wilkinson, Mary J., Green, Nathan B., Sidrys, Algis P., Hallmeyer, Sigrun, Testori, Douglas J., Sridhar, Srikala, Chang, Jose, Sun, Qiang, Jara-Sanchez, Carlos, Rubio, Xabier, Garrido, Maria Lomas, De La Haba Rodriguez, Juan Rafael, Perello Martorell, Antonia, Avelia Mestre, Antoni, Rifa Ferrer, Julio, del Barco Berron, Sonia, Nagy, Zsuzsanna, Tanaka, Maki, Im, Young-Hyuck, Carroll, Robert R., Dickerson, Laura C., Mace, Joseph R., Rivera, Ragene, Klein, Leonard M., Ruxer, Robert, Wilks, Sharon T., Kotasek, Dusan, Popov, Vasil, Taskova, Violina, Marinova-Venkova, Violetka, Timcheva, Constanta, Desbiens, Christine, Ayoub, Jean-Pierre, Grenier, Debjani, Marschner, Norbert, Tesch, Hans, Lueck, Hans-Joachim, Janssen, Jan, Schwaner, Ingo, Wahlstrom, Stine, Brix, Eva Harder, Vallentin, Susanne, Kristensen, Dan, Andreeva, Anna, Glavicic, Vesna, Calvo Plaza, Isabel, Anton Torres, Antonio, Veyret, Corinne, Bergerat, Jean-Pierre, Bourbouloux, Emmanuelle, Ella, Wendy Ann, Algurafi, Hafiz, Robinson, Anne, Kim, Seung Jin, Taguchi, Tetsuya, Juozaityte, Elona, Madretsma, Stanley, Radema, Sandra, Czerniawska-Meier, Malgorzata, Rogowski, Wojciech, Wagnerova, Maria, Richards, Donald A., Tan-Chiu, Elizabeth, Vasileios, Asskikis, Henderson, Charles Arthur, Holden, Viran Roger, Wang, Xiaojia, Tong, Zhongsheng, Yang, Junlan, Gonzalez, Manuel Enrique, Rezai, Mahdi, Hackmann, John, de Dueñas, Eduardo Martinez, de las Heras, Begoña Bermejo, Dourthe, Louis Marie, Chocteau-Bouju, Dorothee, Bougnoux, Philippe, Kakolyris, Stylianos, Kalofonos, Haralabos, Pectasidis, Dimitrios, Ng, Ting Ying, Pajkos, Gabor, Somogyine, Eva Ezer, Tonini, Giuseppe, Giuffrida, Dario, Takao, Shintaro, Ishitobi, Makoto, Inaji, Hideo, Tokuda, Yutaka, Wozniak, Katarzyna, Lungulescu, Dan, Lu, Yen-Shen, Chang, King-Jen, Hill, Julian, Croot, Christopher Charles, Dekker, Albert, Belman, Neil D., Conde, Miguel, Michaelson, Richard A., Kemmer, Kathleen, Chui, Stephen, Luoh, Shiuh-Wen, Nahum, Kenneth, Greenspan, Andrew R., Nichols, Joni C., Encarnacion, Carlos A., Niederman, Thomas M.J., Lee, Theresa, Alexander, Roland, Gordon, Robert, Tomova, Antoanet, Rauch, Daniel, Popescu, Razvan Andrei, Rojas, Gustavo Adolfo, Vanasek, Jaroslav, Neunhoeffer, Tanja, Barinoff, Jana, Graffunder, Gerd, Wolfgang, Abenhardt, Bojko, Peter, Heinrich, Bernhard, von der Assen, Albert, Antonovic, Bogovic Jurij, Adrian, Lene, Ramos Vazquez, Manuel, Gonzalez Santiago, Santiago, Dieras, Veronique, Bishop, Jill Mercia, Perren, Timothy John, Varthalitis, Ioannis, Mavroudis, Dimitris, Georgoulias, Vassilis, Chow, Louis W.C., Yau, Chung Cheung Thomas, Liang, Raymond Hin-Suen, Pikó, Béla, Wéber, Agnes, Kaufman, Bella, Drumea, Karen, Nuzzo, Francesco, De Matteis, Andrea, Carteni, Giacomo, Tokunaga, Eriko, Ishida, Mayumi, Ohno, Shinji, Sato, Nobuaki, Kuroi, Katsumasa, Nishimura, Reiki, Watanabe, Junichiro, Choi, Yoon Ji, Park, Kyong Hwa, Wojtukiewicz, Marek, Jassem, Jacek, Loman, Niklas, Askoy, Sercan, Altundag, Mustafa Kadri, Saip, Pinar, Ali, Muhammad Amjad, Wade, James Lloyd, III, Chien, Amy Jo, Brandt, Debra, Novik, Yelena, Jani, Chirag, Rice, Robert L., Gaffar, Yousuf A. R, Keaton, Mark R., Bajaj, Rajesh, Kimmick, Gretchen, Campbell, David, Turnquest, Theodore, Lucas, Sideras, Dube, Pierre, Xu, Binghe, Schilling, Joerg, Apel, Klaus, Vestlev, Peter Michael, Jensen, Brita Bjerregaard, Haahr, Vera, Lescure, Alvaro Rodriguez, Grana Suarez, Begona, Saura Manich, Cristina, Jacquin, Jean-Philippe, Samreen, Ahmed, Boiangiu, Ion, Dank, Magdolna, Falci, Cristina, Jirillo, Antonio, Cinieri, Saverio, Ueno, Takayuki, Sato, Fumiaki, Yamashiro, Hiroyasu, Sugie, Tomoharu, Lee, Keun Seok, Ro, Jung Sil, Park, In Hae, Bustam, Anita Zarina, Suszko-Kazarnowicz, Malgorzata, Piktel, Artur, Krzemieniecki, Krzysztof, Iorga, Polizenia Georgeta, Yap, Yoon Sim, Kakalejcik, Marian, Sevinc, Alper, Ozguroglu, Mustafa, Chen, Shin-Cheh, Greenberg, Richard H., Eisemann, Allan Daniel, Droder, Robert, Abbasi, M. Rashid, Vaysburd, Marina, Caldera, Humberto Jose, Haley, Barbara Bacsik, Robin, Erwin, Inhorn, Roger C., Hufnagel, David, Kenyon, Peter D., Spremulli, Ellen, Silverman, Paula, Jain, Sharad, Weigand, Robert, Mebis, Jeroen, Koynova, Tatyana, Lesperance, Bernard, Prausova, Jana, Kohne, Claus-Henning, Schneeweiss, Andreas, Jackisch, Christian, Fuxius, Stefan, Cubedo Cervera, Ricardo, Urruticoechea Ribate, Ander, Pernas Simon, Sonia, Valero Gallego, Jose, Arcusa Lanza, Angels, del Pilar Alvarez, Maria, Florian Gerico, Jesus, Cany, Laurent, Stebbing, Justin, Labudovic, Dejan, Gugic, Damir, Vrbanec, Damir, Roila, Fausto, Barni, Sandro, Bidoli, Paolo, Mukai, Hirofumi, Bermudez, Vanessa, Eniu, Alexandru, Mirtsching, Barry C., Ibrahim, Emad, Trey, Joan, Hergenroeder, Paul Francis, Mahmood, Aftab, Gonzalez, Anneliese, Kaplan, Edward H., Ban, Stacy, Patel, Dhimant, Clowney, Billy, Hoelzer, Karen, Schwartz, Garry H., Salkeni, Mohamed, Abraham, Jame, Narula, Sunil, Jabboury, Khaled, Mocharnuk, Robert Scott, McDonough, Richard H., Sikes, David H., Kawanchi, Ronald H., Schlabach, Larry, McCachren, Samuel Spence, Jr., Cosgriff, Thomas M., Dreisbach, Luke, DeMichele, Angela, Pawl, Lawrence, Lucas, Jennifer, Shinn, Lowell C., Alkhouri, Nabiel, Monga, Manish, Lindquist, Deborah L., Anderson, Thomas C., Khurshid, Humera, Witherby, Sabrina, Erickson, Nicholette, Traynor, Ann, Bose, Ron, Pluard, Timothy J., Jones, Michael C., Prakash, Sucharu, Volterra, Fabio, Capo, Gerardo, Flaherty, Lawrence E., Gartner, Elaina, Baidas, Said, Okazaki, Ian, Nguyen, Bichlien, Rakowski, Thomas, Oliff, Ira, Leach, Joseph W., Anderson, Daniel, Kubiak, Kendra, Tsai, Michaela, Vroman, Philippe, Deleu, Ines, Lybaert, Willem, Borms, Marleen, Couture, Felix, Wilson, Jonathan J., Hunt, Gordon, Holland, David R., Mingrone, Walter, Wang, Shusen, Liu, Donggeng, Jiang, Zefei, Benesova, Vera, Smakal, Martin, Garnolova, Petra, Vesper, Anne-Sophie, Neumann, Monika, Janni, Wolfgang, Liedtke, Cornelia, Fischer, Dorothea, Grischke, Eva-Maria, Seeger, Dietmar, Moebus, Volker, Prechtl, Anita, Carlos Camara Toral, Juan, Sanchez Munoz, Alfonso, Gonzalez Jimenez, Sonia, Cassinello Espinosa, Javier, Cirauqui, Beatriz, Margeli Vila, Mireia, Batista Lopez, Norberto, Chacon Lopez-Muniz, Jose Ignacio, de la Cruz Mora, Miguel Angel, Mailliez, Audrey, Vanlemmens, Laurence, Pouessel, Damien, Espie, Marc, Conibear, John, Roylance, Rebecca, Harnett, Adrian, Geffen, David, Ruggeri, Enzo Maria, Gamucci, Teresa, Van Groeningen, Cees J., Banas, Renata, Alkis, Necati, Hou, Ming-Feng, Krie, Amy K., Vrindavanam, Nandagopal S., Howard, Orion M., Citrin, Dennis, Morginstin, Mark S., Desai, Ajit, Sanchez, Ines J., Nixon, David Allen, Jr., Beatty, Patrick G., Edmiston, Kathryn, McLaughlin, Marilyn, Eneman, Jonathan D., Lynch, Cynthia A., O'Brien, Edward, Call, Justin A., Lanier, Keith S., Conlin, Alison, Brooks, Donald J., McIntyre, Kristi, Saltzman, Marc A., Castine, Michael J., III, Ortega, Gregory L., Choi, Young M., Reynolds, Craig H., Brescia, Frankie Ann, Kramer, Rita, Kohn, Aimee D., Micha, John P., Rhee, Jessica M., Shah, Satish, Riseberg, David A., Patterson, William Kevin, Salmon, Jean-Paul, Andre, Chantal, Bols, Alain, D'hondt, Randal, Luce, Sylvie, Nouwynck, Claire, Pelgrims, Gino, Richard, Vincent, Verschuere, Johan, Geldhof, Kurt, Caspar, Clemens, Luo, Rongcheng, Bednarik, Otakar, Schwedler, Kathrin, Schmidt, Marcus, Neumeister, Romy, Bischoff, Joachim, Rack, Brigitte, Repp, Roland, Fries, Stefan, Adrion, Ralf, Schulz, Volker, Klare, Peter, Danei, Mahmoud, Ossenbuhl, Dirk, Kusche, Jakob Manfred, Griesinger, Frank, Baena Canada, Jose Manuel, Martinez del Prado, Purificacion, Machover, David, Mayeur, Didier, Trufflandier, Nathalie, Delecroix, Valerie, Mousseau, Mireille, Mouret-Reynier, Marie-Ange, Nabholtz, Jean-Marc, Chetiyawardana, Anula D., Papandreou, Christos, Hornyak, Lajos, Faluhelyi, Zsolt, Simo, Erzsebet, Di Palma, Mario, Cognetti, Francesco, Gorzegno, Gabriella, Dogliotti, Luigi, Gridelli, Cesare, Falcone, Alfredo, Soto Parra, Hector, Buscarino, Calogero, Im, Seock-Ah, Sanchez Llamas, Benito, Dercksen, Wouter, Erdkamp, Franciscus, Ruit, Jan B., Braun, Hans, Portielje, Joanneke E.A., Ciltas, Aydin, Buyukberber, Suleyman, Benekli, Mustafa, Zahalsky, Andrew J., Jaslow, Rebecca, Thomas, Gary W., Maini, Archana, Wiznitzer, Israel, Khojasteh, Ali, Francisco Gonzalez, Manuel, Kong, Lynn R., Padmanabhan, Aruna, Conkright, William A., Swain, Sandra M., Faig, Douglas E., Jain, Kirti, Yanagihara, Ronald H., Ottaviano, Yvonne, Delmas, Andrew, Steele, Heather A., Rainey, Gordon K., Harris, Penelope J., Burris, Jason K., Rupard, Erik J., Tan, Esther, Whitworth, Pat W., Bova, Abby R., Anderson, Ian C., Shirinian, Mihran, Tin-u, Caesar, O'Rourke, Timothy J., Roberts, Michael S., Francisco, Michael, Pierson, A. Scott, Byeff, Peter D., Kovach, Peter A., Caton, John R., Jr., Rarick, Mark Urban, Schimidt, William G., Jr., Stopeck, Alison T., Swart, Rachel, Carrillo Flores, Maria Regina, Alemany, Carlos A., Lozada, Brennely, Weinstein, Paul L., Wang, Wei, Porubcin, Michael, Ellison, David M., Geils, George F., Rivera, Edgardo, Charif, Mahmoud, Martin, Miguel, Holmes, Frankie A, Ejlertsen, Bent, Delaloge, Suzette, Moy, Beverly, Iwata, Hiroji, von Minckwitz, Gunter, Chia, Stephen K L, Mansi, Janine, Barrios, Carlos H, Gnant, Michael, Tomašević, Zorica, Denduluri, Neelima, Šeparović, Robert, Gokmen, Erhan, Bashford, Anna, Ruiz Borrego, Manuel, Kim, Sung-Bae, Jakobsen, Erik Hugger, Ciceniene, Audrone, Inoue, Kenichi, Overkamp, Friedrich, Heijns, Joan B, Armstrong, Anne C, Link, John S, Joy, Anil Abraham, Bryce, Richard, Wong, Alvin, Moran, Susan, Yao, Bin, Xu, Feng, Auerbach, Alan, Buyse, Marc, Chan, Arlene

Source: In The Lancet Oncology December 2017 18(12):1688-1700

A multi-center phase II study of high dose interleukin-2 sequenced with vemurafenib in patients with BRAF-V600 mutation positive metastatic melanoma

Authors: Clark, Joseph, Singh, Jatinder, Ernstoff, Marc, Lao, Christopher, Flaherty, Lawrence, Logan, Theodore, Curti, Brendan, Agarwala, Sanjiv, Taback, Bret, Cranmer, Lee, Lutzky, Jose, Luna, Theresa, Aung, Sandra, Lawson, David

Source: Journal for immunotherapy of cancer. 6(1):1-8

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175094813.0x000001&indx=1&recIds=ETOCvdc_100175094813.0x000001

Combination of vemurafenib and cobimetinib in patients with advanced BRAFV600-mutated melanoma: a phase 1b study

Authors: Ribas, Antoni, Gonzalez, Rene, Pavlick, Anna, Hamid, Omid, Gajewski, Thomas F, Daud, Adil, Flaherty, Lawrence, Logan, Theodore, Chmielowski, Bartosz, Lewis, Karl, Kee, Damien, Boasberg, Peter, Yin, Ming, Chan, Iris, Musib, Luna, Choong, Nicholas, Puzanov, Igor, McArthur, Grant A

Source: In Lancet Oncology August 2014 15(9):954-965

Southwest Oncology Group SOOO8: A Phase III Trial of High-Dose Interferon Alfa-2b Versus Cisplatin, Vinblastine, and Dacarbazine, Plus Interleukin-2 and Interferon in Patients With High-Risk Melanoma—An Intergroup Study of Cancer and Leukemia Group B, Children's Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group

Authors: Flaherty, Lawrence E., Othus, Megan, Atkins, Michael B.

Source: Journal of clinical oncology. 32(33):3771-3778

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN600173027&indx=1&recIds=ETOCRN600173027

Biochemotherapy of melanoma

Authors: Flaherty, Lawrence E., Gadgeel, Shirish M.

Source: In Seminars in Oncology October 2002 29(5):446-455

An Open-Label, Randomized, Multi-Center Study Comparing the Sequence of High Dose Aldesleukin (Interleukin-2) and Ipilimumab (Yervoy) in Patients with Metastatic Melanoma.

Authors: Hasanov, Merve, Milton, Denái R., Sharfman, William H., Taback, Bret, Cranmer, Lee D., Daniels, Gregory A., Flaherty, Lawrence, Hallmeyer, Sigrun, Milhem, Mohammed, Feun, Lynn, Hauke, Ralph, Doolittle, Gary, Gregory, Nancy, Patel, Sapna

Source: OncoImmunology; 2021, Vol. 10 Issue 1, p1-10, 10p

Subject Terms: INTERLEUKIN-2, CEREBRAL hemorrhage, IPILIMUMAB, MELANOMA, PATIENTS' attitudes, IMMUNOTHERAPY

Phase III Study of Adjuvant Ipilimumab (3 or 10 mg/kg) Versus High-Dose Interferon Alfa-2b for Resected High-Risk Melanoma: North American Intergroup E1609.

Authors: Tarhini, Ahmad A., Lee, Sandra J., Hodi, F. Stephen, Rao, Uma N. M., Cohen, Gary I., Hamid, Omid, Hutchins, Laura F., Sosman, Jeffrey A., Kluger, Harriett M., Eroglu, Zeynep, Koon, Henry B., Lawrence, Donald P., Kendra, Kari L., Minor, David R., Lee, Carrie B., Albertini, Mark R., Flaherty, Lawrence E., Petrella, Teresa M., Streicher, Howard, Sondak, Vernon K.

Source: Journal of Clinical Oncology; 2/20/2020, Vol. 38 Issue 6, p567-575, 10p

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Adjuvant therapy of melanoma: is pegylated interferon alfa-2b what we've been waiting for?

Authors: Sondak, Vernon K., Flaherty, Lawrence E.

Source: Lancet; July 12-18 2008, Vol. 372, p89-90, 2p

Phase III Randomized Study of 4 Weeks of High-Dose Interferon-α-2b in Stage T2bNO, T3a-bNO, T4a-bNO, and T1-4N1a-2a (microscopic) Melanoma: A Trial of the Eastern Cooperative Oncology Group-American College of Radiology Imaging Network Cancer...

Authors: Agarwala, Sanjiv S., Lee, Sandra J., Yip, Waiki, Rao, Uma N., Tarhini, Ahmad A., Cohen, Gary I., Reintgen, Douglas S., Evans, Terry L., Brell, Joanna M., Albertini, Mark R., Atkins, Michael B., Dakhil, Shaker R., Conry, Robert M., Sosman, Jeffrey A., Flaherty, Lawrence E., Sondak, Vernon K., Carson, William E., Smylie, Michael G., Pappo, Alberto S., Kefford, Richard F.

Source: Journal of Clinical Oncology; 3/10/2017, Vol. 35 Issue 8, p885-892, 11p

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