Singlet Oxygen Leads to Structural Changes to Chloroplasts during their Degradation in the Arabidopsis thaliana plastid ferrochelatase two Mutant

Authors: Fisher, Karen E, Krishnamoorthy, Praveen, Joens, Matthew S, Chory, Joanne, Fitzpatrick, James A J, Woodson, Jesse D

Source: Plant & cell physiology. 63(2):248-264

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142850756.0x000001&indx=1&recIds=ETOCvdc_100142850756.0x000001

Poly-basic peptides and polymers as new drug candidates against Plasmodium falciparum.

Authors: Sivakumar, Roshan, Floyd, Katherine, Erath, Jessey, Jacoby, Alex, Kim Kim, Jenny, Bayguinov, Peter O., Fitzpatrick, James A. J., Goldfarb, Dennis, Jovanovic, Marko, Tripathi, Abhai, Djuranovic, Sergej, Pavlovic-Djuranovic, Slavica

Source: Malaria Journal; 8/1/2024, Vol. 23 Issue 1, p1-18, 18p

Vesicular Glutamatergic Transmission in Noise-Induced Loss and Repair of Cochlear Ribbon Synapses

Authors: Kim, Kyunghee X., Payne, Shelby, Yang-Hood, Aizhen, Li, Song-Zhe, Davis, Bethany, Carlquist, Jason, V-Ghaffari, Babak, Gantz, Jay A., Kallogjeri, Dorina, Fitzpatrick, James A. J.

Source: Journal of neuroscience. 39(23):4434-4447

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620315007&indx=1&recIds=ETOCRN620315007

Catheterization alters bladder ecology to potentiate Staphylococcus aureus infection of the urinary tract

Authors: Walker, Jennifer N., Flores-Mireles, Ana L., Pinkner, Chloe L., Schreiber, Henry L., Joens, Matthew S., Park, Alyssa M., Potretzke, Aaron M., Bauman, Tyler M., Pinkner, Jerome S., Fitzpatrick, James A. J., Desai, Alana, Caparon, Michael G., Hultgren, Scott J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2017 Oct 01. 114(41), E8721-E8730.

Access URL: https://www.jstor.org/stable/26488727

Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue.

Authors: Dhavale, Dhruva D., Barclay, Alexander M., Borcik, Collin G., Basore, Katherine, Berthold, Deborah A., Gordon, Isabelle R., Jialu Liu, Milchberg, Moses H., O’Shea, Jennifer Y., Rau, Michael J., Smith, Zachary, Soumyo Sen, Summers, Brock, Smith, John, Warmuth, Owen A., Perrin, Richard J., Perlmutter, Joel S., Qian Chen, Fitzpatrick, James A. J., Schwieters, Charles D.

Source: Nature Communications; 3/29/2024, Vol. 15 Issue 1, p1-18, 18p, 1 Color Photograph, 2 Black and White Photographs

A single transcription factor is sufficient to induce and maintain secretory cell architecture

Authors: Lo, Hei-Yong G., Jin, Ramon U., Sibbel, Greg, Liu, Dengqun, Karki, Anju, Joens, Matthew S., Madison, Blair B., Zhang, Bo, Blanc, Valerie, Fitzpatrick, James A. J.

Source: Genes & development. 31(2):154-171

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN610238177&indx=1&recIds=ETOCRN610238177

Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes.

Authors: Deveryshetty, Jaigeeth, Chadda, Rahul, Mattice, Jenna R., Karunakaran, Simrithaa, Rau, Michael J., Basore, Katherine, Pokhrel, Nilisha, Englander, Noah, Fitzpatrick, James A. J., Bothner, Brian, Antony, Edwin

Source: Nature Communications; 10/5/2023, Vol. 14 Issue 1, p1-16, 16p

Subject Terms: DOUBLE-strand DNA breaks, BINDING sites, DNA repair, YEAST, SINGLE-stranded DNA

Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance

Authors: Deng, Zengqin, Maksaev, Grigory, Schlegel, Angela M., Zhang, Jingying, Rau, Michael, Fitzpatrick, James A. J., Haswell, Elizabeth S., Yuan, Peng

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174556046.0x000001&indx=1&recIds=ETOCvdc_100174556046.0x000001

Structural and functional analysis of human pannexin 2 channel.

Authors: He, Zhihui, Zhao, Yonghui, Rau, Michael J., Fitzpatrick, James A. J., Sah, Rajan, Hu, Hongzhen, Yuan, Peng

Source: Nature Communications; 3/27/2023, Vol. 14 Issue 1, p1-10, 10p

Subject Terms: FUNCTIONAL analysis, CELL physiology, BRAIN injuries, HOMEOSTASIS, HUMAN beings, PATHOLOGICAL physiology, PERMEABILITY

Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain.

Authors: Pan, Shelei, Yang, Peter H., DeFreitas, Dakota, Ramagiri, Sruthi, Bayguinov, Peter O., Hacker, Carl D., Snyder, Abraham Z., Wilborn, Jackson, Huang, Hengbo, Koller, Gretchen M., Raval, Dhvanii K., Halupnik, Grace L., Sviben, Sanja, Achilefu, Samuel, Tang, Rui, Haller, Gabriel, Quirk, James D., Fitzpatrick, James A. J., Esakky, Prabagaran, Strahle, Jennifer M.

Source: Nature Communications; 1/27/2023, Vol. 14 Issue 1, p1-16, 16p

Subject Terms: X-ray computed microtomography, CEREBROSPINAL fluid, CEREBRAL circulation, GOLD nanoparticles, CENTRAL nervous system, SUBARACHNOID space, RADIOACTIVE tracers, SMALL-angle X-ray scattering

Modern Laser Scanning Confocal Microscopy

Authors: Bayguinov, Peter O., Oakley, Dennis M., Shih, Chien‐Cheng, Geanon, Daniel J., Joens, Matthew S., Fitzpatrick, James A. J.

Source: Current protocols in cytometry. 85(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173318712.0x000001&indx=1&recIds=ETOCvdc_100173318712.0x000001

Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.

Authors: Petroff II, John T., Dietzen, Noah M., Santiago-McRae, Ezry, Deng, Brett, Washington, Maya S., Chen, Lawrence J., Trent Moreland, K., Deng, Zengqin, Rau, Michael, Fitzpatrick, James A. J., Yuan, Peng, Joseph, Thomas T., Hénin, Jérôme, Brannigan, Grace, Cheng, Wayland W. L.

Source: Nature Communications; 11/17/2022, Vol. 13 Issue 1, p1-16, 16p

Subject Terms: ION channels, LIGAND-gated ion channels, BINDING sites, NEURAL transmission, PHOSPHATIDYLGLYCEROL, PHOSPHOLIPIDS

Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel.

Authors: Mount, Jonathan, Maksaev, Grigory, Summers, Brock T., Fitzpatrick, James A. J., Yuan, Peng

Source: Nature Communications; 11/12/2022, Vol. 13 Issue 1, p1-11, 11p

Subject Terms: ION channels, POTASSIUM channels, POTASSIUM ions

Disease-associated mutations within the yeast DNAJB6 homolog Sis1 slow conformer-specific substrate processing and can be corrected by the modulation of nucleotide exchange factors.

Authors: Bhadra, Ankan K., Rau, Michael J., Daw, Jil A., Fitzpatrick, James A. J., Weihl, Conrad C., True, Heather L.

Source: Nature Communications; 8/5/2022, Vol. 13 Issue 1, p1-14, 14p

Subject Terms: NUCLEOTIDE exchange factors, LIMB-girdle muscular dystrophy, HEAT shock proteins, MOLECULAR chaperones, GENETIC mutation, YEAST, PRIONS

Miswiring of Merkel cell and pruriceptive C fiber drives the itch-scratch cycle.

Authors: Feng, Jing, Zhao, Yonghui, Xie, Zili, Zang, Kaikai, Sviben, Sanja, Hu, Xueming, Fitzpatrick, James A. J., Wen, Lu, Liu, Yifei, Wang, Ting, Lawson, Katy, Liu, Qin, Yan, Yan, Dong, Xinzhong, Han, Liang, Wu, Gregory F., Kim, Brian S., Hu, Hongzhen

Source: Science Translational Medicine; 7/13/2022, Vol. 14 Issue 653, p1-9, 9p

Subject Terms: MERKEL cells, ITCHING, IMMUNOELECTRON microscopy, NERVE endings, MECHANORECEPTORS, ELECTRIC batteries

Molecular Diffusion Through Intercellular Spaces of Synovium In Vitro
Orthopaedic Research Society

Authors: Guang, Young, McGrath, Tom M., Klug, Natalie R., Fitzpatrick, James A. J., Pham, Christine, Setton, Lori A.

Source: Transactions of the annual meeting. 65:2204-2204

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN605551243&indx=1&recIds=ETOCCN605551243

Fluorogenic Dendrons with Multiple Donor Chromophores as Bright Genetically Targeted and Activated Probes.

Authors: Szent-Gyorgyi, Christopher, Schmidt, Brigitte F., Fitzpatrick, James A. J.

Source: Journal of the American Chemical Society; August 18 2010, Vol. 132 Issue 32, p11103-11109, 7p

Singlet Oxygen Leads to Structural Changes to Chloroplasts during their Degradation in the Arabidopsis thaliana plastid ferrochelatase two Mutant.

Authors: Fisher, Karen E, Krishnamoorthy, Praveen, Joens, Matthew S, Chory, Joanne, Fitzpatrick, James A J, Woodson, Jesse D

Source: Plant & Cell Physiology; Feb2022, Vol. 63 Issue 2, p248-264, 17p

Subject Terms: REACTIVE oxygen species, ARABIDOPSIS thaliana, CHLOROPLASTS, PHOTOOXIDATIVE stress

Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins.

Authors: Luke, Cliff J., Markovina, Stephanie, Good, Misty, Wight, Ira E., Thomas, Brian J., Linneman, John M., Lanik, Wyatt E., Koroleva, Olga, Coffman, Maggie R., Miedel, Mark T., Gong, Qingqing, Andress, Arlise, Campos Guerrero, Marlene, Wang, Songyan, Chen, LiYun, Beatty, Wandy L., Hausmann, Kelsey N., White, Frances V., Fitzpatrick, James A. J., Orvedahl, Anthony

Source: Communications Biology; 1/12/2022, Vol. 5 Issue 1, p1-25, 25p

Subject Terms: CELL death, CYSTEINE proteinase inhibitors, SERPINS, EPITHELIAL cells, CAENORHABDITIS elegans

Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis.

Authors: Gustafsson, Jenny K., Davis, Jazmyne E., Rappai, Tracy, McDonald, Keely G., Kulkarni, Devesha H., Knoop, Kathryn A., Hogan, Simon P., Fitzpatrick, James A. J., Lencer, Wayne I., Newberry, Rodney D.

Source: eLife; 11/16/2021, p1-29, 29p