Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen—Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design

Authors: Eron, Scott J., Huang, Hongwei, Agafonov, Roman V., Fitzgerald, Mark E., Patel, Joe, Michael, Ryan E., Lee, Tobie D., Hart, Ashley A., Shaulsky, Jodi, Nasveschuk, Christopher G.

Source: ACS chemical biology. 16(11):2228-2243

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628094663&indx=1&recIds=ETOCRN628094663

MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

Authors: Kryukov, Gregory V., Wilson, Frederick H., Ruth, Jason R., Paulk, Joshiawa, Tsherniak, Aviad, Marlow, Sara E., Vazquez, Francisca, Weir, Barbara A., Fitzgerald, Mark E., Tanaka, Minoru, Bielski, Craig M., Scott, Justin M., Dennis, Courtney, Cowley, Glenn S., Boehm, Jesse S., Root, David E., Golub, Todd R., Clish, Clary B., Bradner, James E., Hahn, William C., Garraway, Levi A.

Source: Science, 2016 Mar 01. 351(6278), 1214-1218.

Access URL: http://www.jstor.org/stable/24743195

Diversity-Oriented Synthesis Probe Targets Plasmodium falciparum Cytochrome b Ubiquinone Reduction Site and Synergizes With Oxidation Site Inhibitors

Authors: Lukens, Amanda K., Heidebrecht, Richard W., Mulrooney, Carol, Beaudoin, Jennifer A., Comer, Eamon, Duvall, Jeremy R., Fitzgerald, Mark E., Masi, Daniela, Galinsky, Kevin, Scherer, Christina A., Palmer, Michelle, Munoz, Benito, Foley, Michael, Schreiber, Stuart L., Wiegand, Roger C., Wirth, Dyann F.

Source: The Journal of Infectious Diseases, 2015 Apr 01. 211(7), 1097-1103.

Access URL: http://www.jstor.org/stable/43708798

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Studies directed toward the synthesis of nakadomarin A

Authors: Haimowitz, Thomas, Fitzgerald, Mark E., Winkler, Jeffrey D.

Source: In Tetrahedron Letters 2011 52(17):2162-2164

Chapter 25 - Biohazards: Safety Practices, Operations and Containment Facilities

Authors: Lehner, Noel D.M., Crane, Jonathan T., Mottet, Michael P., Fitzgerald, Mark E.

Source: In Planning and Designing Research Animal Facilities 2009:347-363

Chapter 27 - Introduction to Specifications: General Considerations and Division 1

Authors: Riley, James F., Fitzgerald, Mark E., Lehner, Noel D.M.

Source: In Planning and Designing Research Animal Facilities 2009:377

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Diversity-Oriented Synthesis-FacilitatedMedicinalChemistry: Toward the Development of Novel Antimalarial Agents.

Authors: Comer, Eamon, Beaudoin, Jennifer A., Kato, Nobutaka, Fitzgerald, Mark E., Heidebrecht, Richard W., Lee, Maurice duPont, Masi, Daniela, Mercier, Marion, Mulrooney, Carol, Muncipinto, Giovanni, Rowley, Ann, Crespo-Llado, Keila, Serrano, Adelfa E., Lukens, Amanda K., Wiegand, Roger C., Wirth, Dyann F., Palmer, Michelle A., Foley, Michael A., Munoz, Benito, Scherer, Christina A.

Source: Journal of Medicinal Chemistry; Oct2014, Vol. 57 Issue 20, p8496-8502, 7p

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Back Cover: Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET (ChemMedChem 23/2016).

Authors: Koblan, Luke W., Buckley, Dennis L., Ott, Christopher J., Fitzgerald, Mark E., Ember, Stuart W. J., Zhu, Jin‐Yi, Liu, Shuai, Roberts, Justin M., Remillard, David, Vittori, Sarah, Zhang, Wei, Schonbrunn, Ernst, Bradner, James E.

Source: ChemMedChem; 12/6/2016, Vol. 11 Issue 23, p2638-2638, 1p

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