Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study

Authors: Okubadejo, Njideka, Ojo, Oluwadamilola, Abiodun, Oladunni, Achoru, Charles, Agabi, Osigwe, Agulanna, Uchechi, Akinyemi, Rufus, Ali, Mohammed, Ani-Osheku, Ifeyinwa, Arigbodi, Ohwotemu, Bello, Abiodun, Erameh, Cyril, Farombi, Temitope, Fawale, Michael, Imarhiagbe, Frank, Iwuozo, Emmanuel, Komolafe, Morenikeji, Nwani, Paul, Nwazor, Ernest, Nyandaiti, Yakub, Obiabo, Yahaya, Odeniyi, Olanike, Odiase, Francis, Ojini, Francis, Onwuegbuzie, Gerald, Osaigbovo, Godwin, Osemwegie, Nosakhare, Oshinaike, Olajumoke, Otubogun, Folajimi, Oyakhire, Shyngle, Ozomma, Simon, Samuel, Sarah, Taiwo, Funmilola, Wahab, Kolawole, Zubair, Yusuf, Gams Massi, Daniel, Gueumekane Bila lamou, Eric, Njamnshi Nfor, Leonard, Magnerou, Mélanie Annick, Fogang Fogoum, Yannick, Shalash, Ali, El-FawaI, Hassan, Khedr, Eman, Fawi, Gharib, A. Eltantawi, Mohamed, Salama, Mohamed, El-Jaafary, Shaimaa, Hamed, Sharifa, Tafesse Mengesha, Abenet, Alemayehu Ayele, Biniyam, Melka Oda, Dereje, Zenebe Zewde, Yared, Debebe Gelan, Yohanesse, AkpaIu, Albert, Charway-Felli, Augustina, Stephen Sarfo, Fred, Adjei, Patrick, Obese, Vida, Bocoum, Abdoulaye, Koita, Abdou, Oumar Guinto, Cheick, Coulibaly, Toumany, Maiga, Youssoufa, Kone, Zaynab, Bell, Abiodun, Adebowale, Akintunde A., Akpekpe, John, lyagba, Alagoma, Wulgo, Ali Mohammed, Arabambi, Babawale, Agu, Christian, Dike, Franklin, Ishola, Ismail, Abiodun, Kehinde, Ekenze, Oluchi, Agabi Osigwe, Paul, Balarabe, Salisu, Abubakar, Sani, Williams, Uduak, Fall, Maouly, Mamadou Diop, Alassane, Hilaire Dominique, Ewodo Touna, Mochan, Andre, Modi, Girish, Dindayal, Saiesha, Ali Awadelkareem, Eman, Elsayed, Inas, Dahawi, Maha, Awadelkareem, Mosab Ali, Misbah, Sarah, Mushengez, Brighton, Kimambo, Henrika, Msango, Leonard, Adebayo, Philip, OKeng, Kigocha, Diekker, Marieke, URassa, Sarah, Gouider, Riadh, Ben Djebara, Mouna, Gargouri, Amina, Kacem, Imen, Nasri, Amina, Mrabet, Saloua, Sghaier, Ikram, Mkada, Imen, Atadzhanov, Masharip, Chishimba, Lorraine, Rizig, Mie, Jama, Fatumah, Okunoye, Olaitan, Hardy, John, Houlden, Henry, Singleton, Andrew, Nalls, Mike, Shamim, Ejaz, Jonas, Cabell, Williamson, Jared, Hall, Deborah A., Rosenbaum, Marc, Davis, Staci, Dean, Marissa, Cromer, Candace, Smith, Jenna, Ruffrage, Lauren, Richardson, Joseph, Sipma, Rebeka, Xie, Tao, Padmanaban, Manesh, Warren, Natalie, Mercado, Tomas, Disbrow, Elizabeth, Chauppeta, Brian, Thomas-Dean, Fermine, Toms, Jamie, Lofton, Katelyn, Rawls, Ashley, Rizer, Kyle, Black, Nieci, Solle, Justin, O'Grady, Alyssa, Sherer, Todd, Fiske, Brian, Başak, A. Nazlı, Tan, Ai Huey, Noyce, Alastair, Akpalu, Albert, Espay, Alberto, Martínez-Carrasco, Alejandro, Medina, Alex, Zimprich, Alexander, Brice, Alexis, Karimova, Altynay, Hernandez, Alvaro, Illarionova, Anastasia, Quattrone, Andrea, Singleton, Andrew B, Sobering, Andrew K., Vinuela, Angel, Sanyaolu, Arinola, Schumacher-Schuh, Artur F., Kishore, Asha, Ahmad-Annuar, Azlina, Al Mubarak, Bashayer, Tang, Beisha, Pizarro Galleguillos, Benjamin, Jeon, Beomseok, Siddiqi, Bernadette, Casey, Bradford, Mollenhauer, Brit, Carroll, Camille, Rieder, Carlos, Pantazis, Caroline B., Comart, Charisse, Lin, Chin-Hsien, Klein, Christine, Bale, Claire, Shepherd, Claire E, Wegel, Claire, Blauwendraat, Cornelis, Vitale, Dan, Martinez-Ramirez, Daniel, Hall, Deborah, Hernandez, Dena, KP, Divya, Nguyen, Duan, Fon, Edward A., Dadiotis, Efthymios, Riley, Ekemini, Iakovenko, Elena, Stafford, Ellie, Gatto, Emilia M, Valente, Enza Maria, Vollstedt, Eva-Juliane, Faghri, Faraz, Genc, Gencer, Xiromerisiou, Georgia, Hadjigorgiou, Georgios, Hiu-Fai Chan, Germaine, Arboleda, Gonzalo, Kaishibayeva, Gulnaz, Höglinger, Günter, Leonard, Hampton, Madoev, Harutyun, Iwaki, Hirotaka, Chen, Honglei, Wu, Hsiu-Chuan, Shang, Huifang, Morris, Huw R, F. Mata, Ignacio, Keller Sarmiento, Ignacio Juan, Dagklis, Ioannis, Tarnanas, Ioannis, Aasly, Jan O., Hoenicka, Janet, Corvol, Jean-Christophe, Foo, Jia Nee, Guo, Jifeng, Junker, Johanna, Carr, Jonathan, Kim, Jonggeol Jeff, Orozco, Jorge, Jankovic, Joseph, Shulman, Joshua, Hunter, Julie, Solle, Justin C., Murphy, Kaileigh, Nuytemans, Karen, Kieburtz, Karl, Lohmann, Katja, Marek, Kenneth, Mok, Kin Ying, Kumar, Kishore, Levine, Kristin, Chahine, Lana M., Lange, Lara M., Pihlstrøm, Lasse, Screven, Laurel, Stefanis, Leonidas, Shulman, Lisa, Marsili, Luca, Parnetti, Lucilla, Kuhl, Maggie, Funayama, Manabu, Sharma, Manu, Tan, Manuela, Kauffman, Marcelo, Miranda, Marcelo, Bustamante, Maria Leonor, Stamelou, Maria, Periñan Tocino, Maria Teresa, Cornejo-Olivas, Mario, Jimenez del Rio, Marlene, Makarious, Mary B, Koretsky, Mathew, Rodriguez-Violante, Mayela, Ellis, Melina, Avenali, Micol, Rentería, Miguel E., Inca-Martines, Miguel z, Nalls, Mike A., Ibrahim Norlinah, Mohamed, Umair, Muhammad, Ip, Nancy, Louie, Naomi, Cheung, Nelson Yuk-Fai, Mencacci, Niccolò Emanuele, Wood, Nicholas, Williams, Nigel, Hattori, Nobutaka, Abdul Murad, Nor Azian, Ibrahim, Norlinah Mohamed, Monchi, Oury, Öztop Çakmak, Özgür, Öztop Çakmak, Patricio Öztop Çakmak, Lewis, Patrick Alfryn, Pastor, Pau, Reyes-Pérez, Paula, Saffie Awad, Paula, Chana, Pedro, Chan, Phillip, Kung, Pin-Jui, Chan, Piu, Pal, Pramod, Lingappa Kukkle, Prashanth, Ojha, Rajeev, Kaiyrzhanov, Rauan, Krüger, Rejko, Amouri, Rim, Weil, Rimona, Rajan, Roopa, Alcalay, Roy, Wu, Ruey-Meei, Borgohain, Rupam, Sassi, Samia Ben, Khachatryan, Samson, Bandres-Ciga, Sara, El-Sadig, Sarah, Wu, Serena, Groppa, Sergio, Azmin, Shahrul, Lim, Shen-Yang, Ur-Rehman, Shoaib, Ertan, Sibel, Stott, Simon, Jasaitye, Simona, Chowdhury, Sohini, Dumanis, Sonya, Bardien, Soraya, Lubbe, Steven, Koks, Sulev, Dey, Sumit, Foroud, Tatiana, Fon, Ted, Beach, Thomas, Gasser, Thomas, Anderson, Tim, Nguyen, Toan, Schirinzi, Tommaso, Shiraishi, Tomotaka, Pitcher, Toni, Tumas, Vitor, Mohamed, Wael, Kamel, Walaa A., Luo, Wei, Zhou, Xiaopu, Zewde, Yared Z., Song, Yeajin, Wen, Yi, Wu, Yihru, Joong Kim, Yun, Tavadyan, Zaruhi, Fang, Zih-Hua, Ojo, Oluwadamilola Omolara, Crea, Peter Wild, Abiodun, Oladunni Victoria, Levine, Kristin S, Abubakar, Sani Atta, Achoru, Charles Obiora, Adeniji, Olaleye Akinmola, Agabi, Osigwe Paul, Koretsky, Mathew J, Hall, Deborah A, Akinyemi, Rufus Olusola, Ali, Mohammed Wulgo, Shamim, Ejaz A, Padmanaban, Mahesh, Arigbodi, Ohwotemu Michael, Standaert, David G, Bello, Abiodun Hamzat, Dean, Marissa N, Erameh, Cyril Oshomah, Farombi, Temitope Hannah, Fawale, Michael Bimbola, Billingsley, Kimberley J, Imarhiagbe, Frank Aiwansoba, Jerez, Pilar Alvarez, Iwuozo, Emmanuel Uzodinma, Baker, Breeana, Komolafe, Morenikeji Adeyoyin, Malik, Laksh, Nwani, Paul Osemeke, Daida, Kensuke, Nwazor, Ernest Okwundu, Miano-Burkhardt, Abigail, Nyandaiti, Yakub Wilberforce, Obiabo, Yahaya Olugbo, Kluss, Jillian H, Odeniyi, Olanike Adedoyin, Hernandez, Dena G, Odiase, Francis Ehidiamen, Tayebi, Nahid, Ojini, Francis Ibe, Sidranksy, Ellen, Onwuegbuzie, Gerald Awele, D'Souza, Andrea M, Osaigbovo, Godwin Osawaru, Berhe, Bahafta, Reed, Xylena, Oshinaike, Olajumoke Olufemi, Leonard, Hampton L, Otubogun, Folajimi Morenikeji, Alvarado, Chelsea X, Oyakhire, Shyngle Imiewan, Ozomma, Simon Izuchukwu, Samuel, Sarah Chabiri, Taiwo, Funmilola Tolulope, Wahab, Kolawole Wasiu, Zubair, Yusuf Agboola, Kim, Jonggeol Jeffrey, Nalls, Mike A, Heilbron, Karl, Norcliffe-Kaufmann, Lucy, Okubadejo, Njideka Ulunma ^{*, ‡, *}

Source: In The Lancet Neurology November 2023 22(11):1015-1025

Underrepresented Populations in Parkinson's Genetics Research: Current Landscape and Future Directions

Authors: Schumacher‐Schuh, Artur Francisco, Bieger, Andrei, Okunoye, Olaitan, Mok, Kin Ying, Lim, Shen‐Yang, Bardien, Soraya, Ahmad‐Annuar, Azlina, Santos‐Lobato, Bruno Lopes, Strelow, Matheus Zschornack, Salama, Mohamed, Rao, Shilpa C., Zewde, Yared Zenebe, Dindayal, Saiesha, Azar, Jihan, Prashanth, Lingappa Kukkle, Rajan, Roopa, Noyce, Alastair J., Okubadejo, Njideka, Rizig, Mie, Lesage, Suzanne, Mata, Ignacio Fernandez, Gatto, Emilia, Kauffman, Marcelo, Hunter, Julie, Kumar, Kishore, Renteria, Miguel E., Koks, Sulev, Zimprich, Alexander, Schuh, Artur Francisco Schumacher, Santos, Bruno, Rieder, Carlos, Tumas, Vitor, Monchi, Oury, Fon, Ted, Miranda, Marcelo David, Bustamante, Maria Leonor, Olguin, Patricio, Chana, Pedro, Tang, Beisha, Shang, Hui‐Fang, Guo, Ji Feng, Chan, Piu, Luo, Wei, Arboleda, Gonzalo, Orozco, Jorge Luis, Rio, Marlene Jimenez, Hernandez, Alvaro, Ayele, Biniyam, Zenebe, Yared, Brice, Alexis, Corvol, Jean‐Christophe, Illarionova, Anastasia, Mollenhauer, Brit, Klein, Christine, Vollstedt, Eva‐Juliane, Lohmann, Katja, Lange, Lara Mariah, Sharma, Manu, Heutink, Peter, Gasser, Thomas, Fang, Zih‐Hua, Akpalu, Albert, Xiromerisiou, Georgia, Stefanis, Leonidas, Sobering, Andrew, Medina, Alex, Chan, Germaine, Ip, Nancy, Cheung, Nelson Yuk‐Fai, Chan, Phillip, Zhou, XiaoPu, Kishore, Asha, Pal, Pramod, Borgohain, Rupam, Valente, Enza Maria, Avenali, Micol, Schirinzi, Tommaso, Funayama, Manabu, Hattori, Nobu, Shiraishi, Tomotaka, Kruger, Rejko, Tan, Ai Huey, Murad, Nor Azian Abdul, Ibrahim, Norlinah Mohamed, Azmin, Shahrul, Mohamed, Wael, Martinez, Daniel, Violante, Mayela Rodríguez, Anderson, Tim, Pitcher, Toni, Ojo, Oluwadamilola, Aasly, Jan, Pihlstrøm, Lasse, Urrehman, Shoaib, Cornejo‐Olivas, Mario, Vinuela, Angel, Iakovenko, Elena, Foo, Jia Nee, Kim, Yun Joong, Carrasco, Alejandro Martinez, Hoenicka, Janet, Elsadig, Sarah, Lin, Chin‐Shien, Wu, Ruey‐Meei Robin, Wu, Serena, Wu, Yih‐Ru, Sassi, Samia Ben, Genc, Gencer, Basak, Nazli, Çakmak, Özgür Öztop, Ertan, Sibel, Noyce, Alastair, Carroll, Camille, Bale, Claire, Towns, Clodagh, Houlden, Henry, Morris, Huw, Hardy, John, Callanan, Joseph, Mok, Kin, Tan, Manuela, Wood, Nick, Williams, Nigel, Lewis, Patrick, Kaiyrzanov, Rauan, Weil, Rimona, Stott, Simon, Dey, Sumit, O'Grady, Alyssa, Casey, Bradford, Pantazis, Caroline, Wegel, Claire, Vitale, Dan, Hall, Deborah, Shamim, Ejaz, Faghri, Faraz, Leonard, Hampton, Iwaki, Hirotaka, Sarmiento, Ignacio Juan Keller, Kim, Jeff, Shulman, Joshua, Solle, Justin C., Kieburtz, Karl, Marek, Ken, Chahine, Lana, Screven, Laurel, Shulman, Lisa, Kuhl, Maggie, Dean, Marissa, Makarious, Mary, Inca, Miguel, Nalls, Mike, Mencacci, Niccolo, Alcalay, Roy, Murtadha, Ruqaya, Bandres‐Ciga, Sara, Fox, Schuyler, Chowdhury, Sohini, Lubbe, Steven, Xie, Tao, Foroud, Tatiana, Sherer, Todd, Song, Yeajin, Singleton, Andrew, Siddiqi, Bernadette, Fiske, Brian, Blauwendraat, Cornelis, Riley, Ekemini, Nguyen, Duan, Nguyen, Toan, Atadzhanov, Masharip

Source: Movement disorders. 37(8):1593-1604

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Seeking progress in disease modification in Parkinson disease

Authors: Lungu, Codrin, Cedarbaum, Jesse M., Dawson, Ted M., Dorsey, E. Ray, Faraco, Carlos, Federoff, Howard J., Fiske, Brian, Fox, Robert, Goldfine, Andrew M., Kieburtz, Karl, Macklin, Eric A., Matthews, Helen, Rafaloff, Gary, Saunders-Pullman, Rachel, Schor, Nina F., Schwarzschild, Michael A., Sieber, Beth-Anne, Simuni, Tanya, Surmeier, Dalton J., Tamiz, Amir, Werner, Milton H., Wright, Clinton B., Wyse, Richard

Source: In Parkinsonism and Related Disorders September 2021 90:134-141

Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson DiseaseA Randomized Clinical Trial

Authors: Simuni, Tanya, Fiske, Brian, Merchant, Kalpana

Source: JAMA neurology. 78(3):312-320

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN633364162&indx=1&recIds=ETOCRN633364162

Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease

Authors: Lai, Dongbing, Alipanahi, Babak, Fontanillas, Pierre, Schwantes‐An, Tae‐Hwi, Aasly, Jan, Alcalay, Roy N., Beecham, Gary W., Berg, Daniela, Bressman, Susan, Brice, Alexis, Brockman, Kathrin, Clark, Lorraine, Cookson, Mark, Das, Sayantan, Van Deerlin, Vivianna, Follett, Jordan, Farrer, Matthew J., Trinh, Joanne, Gasser, Thomas, Goldwurm, Stefano, Gustavsson, Emil, Klein, Christine, Lang, Anthony E., Langston, J. William, Latourelle, Jeanne, Lynch, Timothy, Marder, Karen, Marras, Connie, Martin, Eden R., McLean, Cory Y., Mejia‐Santana, Helen, Molho, Eric, Myers, Richard H., Nuytemans, Karen, Ozelius, Laurie, Payami, Haydeh, Raymond, Deborah, Rogaeva, Ekaterina, Rogers, Michael P., Ross, Owen A., Samii, Ali, Saunders‐Pullman, Rachel, Schüle, Birgitt, Schulte, Claudia, Scott, William K., Tanner, Caroline, Tolosa, Eduardo, Tomkins, James E., Vilas, Dolores, Trojanowski, John Q., Uitti, Ryan, Vance, Jeffery M., Visanji, Naomi P., Wszolek, Zbigniew K., Zabetian, Cyrus P., Mirelman, Anat, Giladi, Nir, Orr Urtreger, Avi, Cannon, Paul, Fiske, Brian, Foroud, Tatiana

Source: Annals of neurology. 90(1):76-88

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121705203.0x000001&indx=1&recIds=ETOCvdc_100121705203.0x000001

Neurotrophic factors for Parkinson's disease: Current status, progress, and remaining questions. Conclusions from a 2023 workshop.

Authors: Barker, Roger A, Saarma, Mart, Svendsen, Clive N, Morgan, Catherine, Whone, Alan, Fiandaca, Massimo S, Luz, Matthias, Bankiewicz, Krystof S, Fiske, Brian, Isaacs, Lyndsey, Roach, Arthur, Phipps, Thomas, Kordower, Jeffrey H, Lane, Emma L, Huttunen, Henri J, Sullivan, Aideen, O'Keeffe, Gerard, Yartseva, Valeria, Federoff, Howard

Source: Journal of Parkinson's Disease; Nov2024, Vol. 14 Issue 8, p1659-1676, 18p

Subject Terms: GLIAL cell line-derived neurotrophic factor, PARKINSON'S disease, GROWTH factors, NEW trials, GENE therapy

A framework for translating tauopathy therapeutics: Drug discovery to clinical trials.

Authors: Feldman, Howard H., Cummings, Jeffrey L., Boxer, Adam L., Staffaroni, Adam M., Knopman, David S., Sukoff Rizzo, Stacey J., Territo, Paul R., Arnold, Steven E., Ballard, Clive, Beher, Dirk, Boeve, Bradley F., Dacks, Penny A., Diaz, Kristophe, Ewen, Colin, Fiske, Brian, Gonzalez, M. Isabel, Harris, Glenn A., Hoffman, Beth J., Martinez, Terina N., McDade, Eric

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Nov2024, Vol. 20 Issue 11, p8129-8152, 24p

The Parkinson's Disease Genome‐Wide Association Study Locus Browser

Authors: Grenn, Francis P., Kim, Jonggeol J., Makarious, Mary B., Iwaki, Hirotaka, Illarionova, Anastasia, Brolin, Kajsa, Kluss, Jillian H., Schumacher‐Schuh, Artur F., Leonard, Hampton, Faghri, Faraz, Billingsley, Kimberley, Krohn, Lynne, Hall, Ashley, Diez‐Fairen, Monica, Periñán, Maria Teresa, Foo, Jia Nee, Sandor, Cynthia, Webber, Caleb, Fiske, Brian K., Gibbs, J. Raphael, Nalls, Mike A., Singleton, Andrew B., Bandres‐Ciga, Sara, Reed, Xylena, Blauwendraat, Cornelis

Source: Movement disorders. 35(11):2056-2067

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110349403.0x000001&indx=1&recIds=ETOCvdc_100110349403.0x000001

Nonsteroidal Anti‐inflammatory Use and LRRK2 Parkinson's Disease Penetrance

Authors: San Luciano, Marta, Tanner, Caroline M., Meng, Cheryl, Marras, Connie, Goldman, Samuel M., Lang, Anthony E., Tolosa, Eduardo, Schüle, Birgitt, Langston, J. William, Brice, Alexis, Corvol, Jean‐Christophe, Goldwurm, Stefano, Klein, Christine, Brockman, Simone, Berg, Daniela, Brockmann, Kathrin, Ferreira, Joachim J., Tazir, Meriem, Mellick, George D., Sue, Carolyn M., Hasegawa, Kazuko, Tan, Eng King, Bressman, Susan, Saunders‐Pullman, Rachel, Raymond, Deborah, Deik, Andres, Barrett, Matthew James, Cabassa, Jose, Groves, Mark, Hunt, Ann L, Lubarr, Naomi, Miravite, Joan, Palmese, Christina, Sachdev, Rivka, Sarva, Harini, Severt, Lawrence, Shanker, Vicki, Swan, Matthew Carrington, Soto‐Valencia, Jeannie, Johannes, Brooke, Ortega, Robert, Ozelius, Laurie, Alcalay, Roy N, Tang, Ming‐X, Santana, Helen Mejia, Roos, Ernest, Orbe‐Reilly, Martha, Fahn, Stanley, Cote, Lucien, Waters, Cheryl, Mazzoni, Pietro, Ford, Blair, Louis, Elan, Levy, Oren, Rosado, Llency, Ruiz, Diana, Dorovski, Tsvyatko, Clark, Lorraine, Marder, Karen S, Cormier, Florence, Bonnet, Anne‐Marie, Welter, Marie‐Laure, Mesnage, Valerie, Vidailhet, Marie, Roze, Emmanuel, Lacomblez, Lucette, Grabli, David, Mart i Masso, Jose Felix, Martinez, Javier Ruiz, Mondragon Rezola, Elisabet, Alustiza, Ainara Estanga, Pagola, Ana Gorostidi, Pont‐Sunyer, Claustre, Rolan, Dolores Vilas, Fernandez‐Santiago, Ruben, Quintana, Maria, Fernandez, Manel, Maragall, Laura, Hentati, Faycal, Farrer, Matthew, Duda, John, Read, Matt, Middleton, Lefkos, Gibson, Rachel, Trinh, Joanne, Sassi, Samia Ben, Zouari, Mourad, Farhat, Emna, Nabli, Fatma, Aasly, Jan, Warø, Bjørg Johanne, Andersen, Sigrid, Bertoni, John, Carter, Julie, Elmer, Lawrence, Jimenez, Nestor Galvez, Martin, Wayne, Pahwa, Rajesh, Lyons, Kelly, Reich, Stephen, Rodnitzky, Robert, Ramos, Carmen Serrano, Wojcieszek, Joanne, Mirelman, Anat, Gurevich, Tanya, Shira, Anat Bar, Weisz, Mali Gana, Yasinovsky, Kira, Zalis, Maayan, Thaler, Avner, Orr‐Urtreger, Avi, Giladi, Nir, Mountain, Joanna, Mestre, Tiago, Visanji, Naomi, Ghate, Taneera, Singerman, Jennifer, Al Dakheel, Amaal, Connolly, Barbara S, Gasser, Thomas, Conley, Emily Drabant, Mullins, Meghan E, Northover, Carrie, Facheris, Maurizio, Fiske, Brian, Urkowiz, Alison

Source: Movement disorders. 35(10):1755-1764

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108684152.0x000001&indx=1&recIds=ETOCvdc_100108684152.0x000001

Parkinson's Disease Drug Therapies in the Clinical Trial Pipeline: 2024 Update.

Authors: McFarthing, Kevin, Buff, Sue, Rafaloff, Gary, Pitzer, Kenneth, Fiske, Brian, Navangul, Anaya, Beissert, Katelyn, Pilcicka, Aleksandra, Fuest, Rosie, Wyse, Richard K., Stott, Simon R.W.

Source: Journal of Parkinson's Disease; 2024, Vol. 14 Issue 5, p899-912, 14p

Subject Terms: PARKINSON'S disease, THERAPEUTICS, LANGUAGE acquisition, DRUG target, INVESTIGATIONAL therapies

Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation

Authors: Diehl, Frances F., Lewis, Caroline A., Fiske, Brian P., Vander Heiden, Matthew G.

Source: Nature metabolism. 1(9):861-867

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125163576.0x000001&indx=1&recIds=ETOCvdc_100125163576.0x000001

Increased PHGDH expression promotes aberrant melanin accumulation

Authors: Mattaini, Katherine, Sullivan, Mark, Lau, Allison, Fiske, Brian, Bronson, Roderick, Vander Heiden, Matthew

Source: BMC cancer. 19(1):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189313562.0x000001&indx=1&recIds=ETOCvdc_100189313562.0x000001

Twelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson's Disease: The International Linked Clinical Trials Initiative.

Authors: Wyse, Richard K., Isaacs, Tom, Barker, Roger A., Cookson, Mark R., Dawson, Ted M., Devos, David, Dexter, David T., Duffen, Joy, Federoff, Howard, Fiske, Brian, Foltynie, Thomas, Fox, Susan, Greenamyre, J. Timothy, Kieburtz, Karl, Kordower, Jeffrey H., Krainc, Dimitri, Matthews, Helen, Moore, Darren J., Mursaleen, Leah, Schwarzschild, Michael A.

Source: Journal of Parkinson's Disease; 2024, Vol. 14 Issue 4, p657-666, 10p

Subject Terms: PARKINSON'S disease, CLINICAL trials, MEDICAL charities, MOVEMENT disorders, MEDICAL research

Geographic Terms: GRAND Rapids (Mich.)

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Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease

Authors: Dave, Kuldip D., De Silva, Shehan, Sheth, Niketa P., Ramboz, Sylvie, Beck, Melissa J., Quang, Changyu, Switzer, Robert C., III, Ahmad, Syed O., Sunkin, Susan M., Walker, Dan, Cui, Xiaoxia, Fisher, Daniel A., McCoy, Aaron M., Gamber, Kevin, Ding, Xiaodong, Goldberg, Matthew S., Benkovic, Stanley A., Haupt, Meredith, Baptista, Marco A.S., Fiske, Brian K., Sherer, Todd B., Frasier, Mark A.

Source: In Neurobiology of Disease October 2014 70:190-203

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

Authors: Lewis, Caroline A., Parker, Seth J., Fiske, Brian P., McCloskey, Douglas, Gui, Dan Y., Green, Courtney R., Vokes, Natalie I., Feist, Adam M., Vander Heiden, Matthew G., Metallo, Christian M.

Source: In Molecular Cell 17 July 2014 55(2):253-263

PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells

Authors: Israelsen, William J., Dayton, Talya L., Davidson, Shawn M., Fiske, Brian P., Hosios, Aaron M., Bellinger, Gary, Li, Jie, Yu, Yimin, Sasaki, Mika, Horner, James W., Burga, Laura N., Xie, Jianxin, Jurczak, Michael J., DePinho, Ronald A., Clish, Clary B., Jacks, Tyler, Kibbey, Richard G., Wulf, Gerburg M., Di Vizio, Dolores, Mills, Gordon B., Cantley, Lewis C., Vander Heiden, Matthew G.

Source: In Cell 10 October 2013 155(2):397-409