Efficacy of Adjunctive Infliximab vs Placebo in the Treatment of Adults With Bipolar I/II Depression: A Randomized Clinical Trial.

Authors: McIntyre, Roger S., Subramaniapillai, Mehala, Lee, Yena, Pan, Zihang, Carmona, Nicole E., Shekotikhina, Margarita, Rosenblat, Joshua D., Brietzke, Elisa, Soczynska, Joanna K., Cosgrove, Victoria E., Miller, Shefali, Fischer, Eileen Grace, Kramer, Nicole E., Dunlap, Kiley, Suppes, Trisha, Mansur, Rodrigo B.

Source: JAMA Psychiatry; Aug2019, Vol. 76 Issue 8, p783-790, 8p

Subject Terms: CLINICAL trials, INFLIXIMAB, TUMOR necrosis factors, BIPOLAR disorder, HYPOMANIA, ANTI-inflammatory agents, MEDICAL care surveys, ANTIDEPRESSANTS, RESEARCH, INTRAVENOUS therapy, RESEARCH methodology, EVALUATION research, MEDICAL cooperation, ADULT child abuse victims, COMPARATIVE studies, MENTAL depression, BLIND experiment, PHARMACODYNAMICS, CHEMICAL inhibitors, DISEASE complications

Geographic Terms: CANADA, UNITED States