High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

Authors: Nicole A. P. Lieberman, Thaddeus D. Armstrong, Benjamin Chung, Daniel Pfalmer, Christopher M. Hennelly, Austin Haynes, Emily Romeis, Qian-Qiu Wang, Rui-Li Zhang, Cai-Xia Kou, Giulia Ciccarese, Ivano Dal Conte, Marco Cusini, Francesco Drago, Shu-ichi Nakayama, Kenichi Lee, Makoto Ohnishi, Kelika A. Konda, Silver K. Vargas, Maria Eguiluz, Carlos F. Caceres, Jeffrey D. Klausner, Oriol Mitja, Anne Rompalo, Fiona Mulcahy, Edward W. Hook, Irving F. Hoffman, Mitch M. Matoga, Heping Zheng, Bin Yang, Eduardo Lopez-Medina, Lady G. Ramirez, Justin D. Radolf, Kelly L. Hawley, Juan C. Salazar, Sheila A. Lukehart, Arlene C. Seña, Jonathan B. Parr, Lorenzo Giacani, Alexander L. Greninger

Source: Frontiers in Microbiology, Vol 13 (2022)

Subject Terms: Treponema pallidum, syphilis, nanopore, genomics, AlphaFold, trRosetta, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2022.1007056/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/f8331bd84d0e47898e3a5a42a1a23551

Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar.

Authors: Nicole A P Lieberman, Michelle J Lin, Hong Xie, Lasata Shrestha, Tien Nguyen, Meei-Li Huang, Austin M Haynes, Emily Romeis, Qian-Qiu Wang, Rui-Li Zhang, Cai-Xia Kou, Giulia Ciccarese, Ivano Dal Conte, Marco Cusini, Francesco Drago, Shu-Ichi Nakayama, Kenichi Lee, Makoto Ohnishi, Kelika A Konda, Silver K Vargas, Maria Eguiluz, Carlos F Caceres, Jeffrey D Klausner, Oriol Mitjà, Anne Rompalo, Fiona Mulcahy, Edward W Hook, Sheila A Lukehart, Amanda M Casto, Pavitra Roychoudhury, Frank DiMaio, Lorenzo Giacani, Alexander L Greninger

Source: PLoS Neglected Tropical Diseases, Vol 15, Iss 12, p e0010063 (2021)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/f8f88374a8944331bc4a55f2256ab665

CD3ε Expression Defines Functionally Distinct Subsets of Vδ1 T Cells in Patients With Human Immunodeficiency Virus Infection

Authors: Pádraic J. Dunne, Christina O. Maher, Michael Freeley, Katie Dunne, Andreea Petrasca, Judy Orikiiriza, Margaret R. Dunne, Derval Reidy, Siobhan O’Dea, Aisling Loy, Jim Woo, Aideen Long, Thomas R. Rogers, Fiona Mulcahy, Derek G. Doherty

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: human immunodeficiency virus, Vδ1 T cells, CD3ε, interleukin-17, programmed death-1, flow cytometry, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2018.00940/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/c930462f738244bebba9d87e6bd1cf8d

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